Daichi Shigemizu

Affiliations

Medical Genome Center, National Center for Geriatrics and Gerontology, Obu, Japan.
Laboratory for Medical Science Mathematics, RIKEN Center for Integrative Medical Science, Yokohama, Japan.
Department of Medical Science Mathematics, Medical Research Institute, Tokyo Medical and Dental University (TMDU), Tokyo, Japan.

Publications (23)

Identification of intermediate-sized deletions and inference of their impact on gene expression in a human population.

Genome medicine

Avec: Jing Hao Wong , Daichi Shigemizu , Yukiko Yoshii , Shintaro Akiyama , Azusa Tanaka , Hidewaki Nakagawa , Shu Narumiya , Akihiro Fujimoto

A rare functional variant of SHARPIN attenuates the inflammatory response and associates with increased risk of late-onset Alzheimer's disease.

Molecular medicine (Cambridge, Mass.)

Avec: Yuya Asanomi , Daichi Shigemizu , Akinori Miyashita , Risa Mitsumori , Taiki Mori , Norikazu Hara , Kaoru Ito , Shumpei Niida , Takeshi Ikeuchi , Kouichi Ozaki

A functional variant of SHARPIN confers increased risk of late-onset Alzheimer's disease.

Journal of human genetics

Avec: Yuya Asanomi , Daichi Shigemizu , Shintaro Akiyama , Akinori Miyashita , Risa Mitsumori , Norikazu Hara , Takeshi Ikeuchi , Shumpei Niida , Kouichi Ozaki

Bigram-PGK: phosphoglycerylation prediction using the technique of bigram probabilities of position specific scoring matrix.

BMC molecular and cell biology

Avec: Abel Chandra , Alok Sharma , Abdollah Dehzangi , Daichi Shigemizu , Tatsuhiko Tsunoda

Ethnic and trans-ethnic genome-wide association studies identify new loci influencing Japanese Alzheimer's disease risk.

Translational psychiatry

Avec: Daichi Shigemizu , Risa Mitsumori , Shintaro Akiyama , Akinori Miyashita , Takashi Morizono , Sayuri Higaki , Yuya Asanomi , Norikazu Hara , Gen Tamiya , Kengo Kinoshita , Takeshi Ikeuchi , Shumpei Niida , Kouichi Ozaki

Lower DNA methylation levels in CpG island shores of CR1, CLU, and PICALM in the blood of Japanese Alzheimer's disease patients.

PloS one

Avec: Risa Mitsumori , Kazuya Sakaguchi , Daichi Shigemizu , Taiki Mori , Shintaro Akiyama , Kouichi Ozaki , Shumpei Niida , Nobuyoshi Shimoda

Identification of potential blood biomarkers for early diagnosis of Alzheimer's disease through RNA sequencing analysis.

Alzheimer's research & therapy

Avec: Daichi Shigemizu , Taiki Mori , Shintaro Akiyama , Sayuri Higaki , Hiroshi Watanabe , Takashi Sakurai , Shumpei Niida , Kouichi Ozaki

A comparison of machine learning classifiers for dementia with Lewy bodies using miRNA expression data.

BMC medical genomics

Avec: Daichi Shigemizu , Shintaro Akiyama , Yuya Asanomi , Keith A Boroevich , Alok Sharma , Tatsuhiko Tsunoda , Takashi Sakurai , Kouichi Ozaki , Takahiro Ochiya , Shumpei Niida

Whole-genome sequencing reveals novel ethnicity-specific rare variants associated with Alzheimer's disease.

Molecular psychiatry

Avec: Daichi Shigemizu , Yuya Asanomi , Shintaro Akiyama , Risa Mitsumori , Shumpei Niida , Kouichi Ozaki

Association between circulating levels of CXCL9 and CXCL10 and physical frailty in older adults.

Gerontology

Avec: Jiaqi Li , Tohru Hosoyama , Daichi Shigemizu , Mikako Yasuoka , Kaori Kinoshita , Keisuke Maeda , Marie Takemura , Yasumoto Matsui , Hidenori Arai , Shosuke Satake

The HLA-DRB109:01-DQB103:03 haplotype is associated with the risk for late-onset Alzheimer's disease in APOE [Formula: see text]4-negative Japanese adults.

npj aging

Avec: Daichi Shigemizu , Koya Fukunaga , Akiko Yamakawa , Mutsumi Suganuma , Kosuke Fujita , Tetsuaki Kimura , Ken Watanabe , Taisei Mushiroda , Takashi Sakurai , Shumpei Niida , Kouichi Ozaki

GlyStruct: glycation prediction using structural properties of amino acid residues.

BMC bioinformatics

Avec: Hamendra Manhar Reddy , Alok Sharma , Abdollah Dehzangi , Daichi Shigemizu , Abel Avitesh Chandra , Tatushiko Tsunoda

JAMIR-eQTL: Japanese genome-wide identification of microRNA expression quantitative trait loci across dementia types.

Database : the journal of biological databases and curation

Avec: Shintaro Akiyama , Sayuri Higaki , Takahiro Ochiya , Kouichi Ozaki , Shumpei Niida , Daichi Shigemizu

Dementia subtype prediction models constructed by penalized regression methods for multiclass classification using serum microRNA expression data.

Scientific reports

Avec: Yuya Asanomi , Daichi Shigemizu , Shintaro Akiyama , Takashi Sakurai , Kouichi Ozaki , Takahiro Ochiya , Shumpei Niida

Classification and deep-learning-based prediction of Alzheimer disease subtypes by using genomic data.

Translational psychiatry

Avec: Daichi Shigemizu , Shintaro Akiyama , Mutsumi Suganuma , Motoki Furutani , Akiko Yamakawa , Yukiko Nakano , Kouichi Ozaki , Shumpei Niida

Identification of potential blood-based biomarkers for frailty by using an integrative approach.

Gerontology

Avec: Mutsumi Suganuma , Motoki Furutani , Tohru Hosoyama , Risa Mitsumori , Rei Otsuka , Marie Takemura , Yasumoto Matsui , Yukiko Nakano , Shumpei Niida , Kouichi Ozaki , Shosuke Satake , Daichi Shigemizu

DeepInsight: A methodology to transform a non-image data to an image for convolution neural network architecture.

Scientific reports

Avec: Alok Sharma , Edwin Vans , Daichi Shigemizu , Keith A Boroevich , Tatsuhiko Tsunoda

Risk prediction models for dementia constructed by supervised principal component analysis using miRNA expression data.

Communications biology

Avec: Daichi Shigemizu , Shintaro Akiyama , Yuya Asanomi , Keith A Boroevich , Alok Sharma , Tatsuhiko Tsunoda , Kana Matsukuma , Makiko Ichikawa , Hiroko Sudo , Satoko Takizawa , Takashi Sakurai , Kouichi Ozaki , Takahiro Ochiya , Shumpei Niida

Prognosis prediction model for conversion from mild cognitive impairment to Alzheimer's disease created by integrative analysis of multi-omics data.

Alzheimer's research & therapy

Avec: Daichi Shigemizu , Shintaro Akiyama , Sayuri Higaki , Taiki Sugimoto , Takashi Sakurai , Keith A Boroevich , Alok Sharma , Tatsuhiko Tsunoda , Takahiro Ochiya , Shumpei Niida , Kouichi Ozaki

Whole-genome sequencing with long reads reveals complex structure and origin of structural variation in human genetic variations and somatic mutations in cancer.

Genome medicine

Avec: Akihiro Fujimoto , Jing Hao Wong , Yukiko Yoshii , Shintaro Akiyama , Azusa Tanaka , Hitomi Yagi , Daichi Shigemizu , Hidewaki Nakagawa , Masashi Mizokami , Mihoko Shimada

Network-based meta-analysis and the candidate gene association studies reveal novel ethnicity-specific variants in MFSD3 and MRPL43 associated with dementia with Lewy bodies.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics

Avec: Daichi Shigemizu , Yuya Asanomi , Shintaro Akiyama , Sayuri Higaki , Takashi Sakurai , Kengo Ito , Shumpei Niida , Kouichi Ozaki

Identification of potential blood biomarkers for early diagnosis of Alzheimer's disease through immune landscape analysis.

npj aging

Avec: Daichi Shigemizu , Shintaro Akiyama , Risa Mitsumori , Shumpei Niida , Kouichi Ozaki

RNA-Sequencing Analysis Identification of Potential Biomarkers for Diagnosis of Sarcopenia.

The journals of gerontology. Series A, Biological sciences and medical sciences

Avec: Motoki Furutani , Mutsumi Suganuma , Shintaro Akiyama , Risa Mitsumori , Marie Takemura , Yasumoto Matsui , Shosuke Satake , Yukiko Nakano , Shumpei Niida , Kouichi Ozaki , Tohru Hosoyama , Daichi Shigemizu

Réseau de co-auteurs

Shumpei Niida 17 collaborations

Kouichi Ozaki 17 collaborations

Shintaro Akiyama 16 collaborations

Yuya Asanomi 8 collaborations

Risa Mitsumori 8 collaborations

Takashi Sakurai 7 collaborations

Alok Sharma 6 collaborations

Tatsuhiko Tsunoda 5 collaborations

Sayuri Higaki 5 collaborations

Takahiro Ochiya 5 collaborations

Keith A Boroevich 4 collaborations

Mutsumi Suganuma 4 collaborations

Akinori Miyashita 3 collaborations

Taiki Mori 3 collaborations

Norikazu Hara 3 collaborations

Takeshi Ikeuchi 3 collaborations

Tohru Hosoyama 3 collaborations

Marie Takemura 3 collaborations

Yasumoto Matsui 3 collaborations

Shosuke Satake 3 collaborations

Motoki Furutani 3 collaborations

Yukiko Nakano 3 collaborations

Jing Hao Wong 2 collaborations

Yukiko Yoshii 2 collaborations

Azusa Tanaka 2 collaborations

Hidewaki Nakagawa 2 collaborations

Akihiro Fujimoto 2 collaborations

Abdollah Dehzangi 2 collaborations

Akiko Yamakawa 2 collaborations

Shu Narumiya 1 collaboration

Kaoru Ito 1 collaboration

Abel Chandra 1 collaboration

Takashi Morizono 1 collaboration

Gen Tamiya 1 collaboration

Kengo Kinoshita 1 collaboration

Kazuya Sakaguchi 1 collaboration

Nobuyoshi Shimoda 1 collaboration

Hiroshi Watanabe 1 collaboration

Jiaqi Li 1 collaboration

Mikako Yasuoka 1 collaboration

Kaori Kinoshita 1 collaboration

Keisuke Maeda 1 collaboration

Hidenori Arai 1 collaboration

Koya Fukunaga 1 collaboration

Kosuke Fujita 1 collaboration

Tetsuaki Kimura 1 collaboration

Ken Watanabe 1 collaboration

Taisei Mushiroda 1 collaboration

Hamendra Manhar Reddy 1 collaboration

Abel Avitesh Chandra 1 collaboration

Tatushiko Tsunoda 1 collaboration

Rei Otsuka 1 collaboration

Edwin Vans 1 collaboration

Kana Matsukuma 1 collaboration

Makiko Ichikawa 1 collaboration

Hiroko Sudo 1 collaboration

Satoko Takizawa 1 collaboration

Taiki Sugimoto 1 collaboration

Hitomi Yagi 1 collaboration

Masashi Mizokami 1 collaboration

Mihoko Shimada 1 collaboration

Kengo Ito 1 collaboration