Cris Kamperschroer

Affiliations

Department of Immunotoxicology, Pfizer Inc., 558 Eastern Point Road, Groton, Connecticut, 06340, USA.

Publications (13)

A Translational Quantitative Systems Pharmacology Model for CD3 Bispecific Molecules: Application to Quantify T Cell-Mediated Tumor Cell Killing by P-Cadherin LP DART

The AAPS journal

Avec: Alison Betts , Nahor Haddish-Berhane , Dhaval K Shah , Piet H van der Graaf , Frank Barletta , Lindsay King , Tracey Clark , Cris Kamperschroer , Adam Root , Andrea Hooper , Xiaoying Chen

Preclinical Efficacy and Safety Comparison of CD3 Bispecific and ADC Modalities Targeting BCMA for the Treatment of Multiple Myeloma.

Molecular cancer therapeutics

Avec: Siler H Panowski , Tracy C Kuo , Yi Zhang , Amy Chen , Tao Geng , Laura Aschenbrenner , Cris Kamperschroer , Edward Pascua , Wei Chen , Kathy Delaria , Santiago Farias , Marjorie Bateman , Russell G Dushin , Sherman M Chin , Thomas J Van Blarcom , Yik Andy Yeung , Kevin C Lindquist , Allison G Chunyk , Bing Kuang , Bora Han , Michael Mirsky , Ingrid Pardo , Bernard Buetow , Thomas G Martin , Jeffrey L Wolf , David Shelton , Arvind Rajpal , Pavel Strop , Javier Chaparro-Riggers , Barbra J Sasu

A Modeling Framework to Characterize Cytokine Release upon T-Cell-Engaging Bispecific Antibody Treatment: Methodology and Opportunities.

Clinical and translational science

Avec: Xiaoying Chen , Cris Kamperschroer , Gilbert Wong , Dawei Xuan

A Novel GUCY2C-CD3 T-Cell Engaging Bispecific Construct (PF-07062119) for the Treatment of Gastrointestinal Cancers.

Clinical cancer research : an official journal of the American Association for Cancer Research

Avec: Divya Mathur , Adam R Root , Bozena Bugaj-Gaweda , Stephanie Bisulco , Xingzhi Tan , Wei Fang , Jessica C Kearney , Justin Lucas , Magali Guffroy , Jonathan Golas , Cynthia M Rohde , Chad Stevens , Cris Kamperschroer , Kerry Kelleher , Rosemary F Lawrence-Henderson , Erik Upeslacis , Johnny Yao , Jatin Narula , Edward R LaVallie , Diane R Fernandez , Bernard S Buetow , Edward Rosfjord , Laird Bloom , Lindsay E King , Lioudmila Tchistiakova , Anhco Nguyen , Puja Sapra

Summary of a workshop on preclinical and translational safety assessment of CD3 bispecifics.

Journal of immunotoxicology

Avec: Cris Kamperschroer , Jacintha Shenton , Hervé Lebrec , John K Leighton , Paul A Moore , Oliver Thomas

Current approaches to evaluate the function of cytotoxic T-cells in non-human primates.

Journal of immunotoxicology

Avec: Cris Kamperschroer , Brendon Frank , Caroline Genell , Hervé Lebrec , Shermaine Mitchell-Ryan , Brigitte Molinier , Courtni Newsome , Marie-Soleil Piche , Daniel Weinstock , Mark Collinge , Wendy Freebern , Daniel Rubio

Correction to: A Translational Quantitative Systems Pharmacology Model for CD3 Bispecific Molecules: Application to Quantify T Cell-Mediated Tumor Cell Killing by P-Cadherin LP DART®.

The AAPS journal

Avec: Alison Betts , Nahor Haddish-Berhane , Dhaval K Shah , Piet H van der Graaf , Frank Barletta , Lindsay King , Tracey Clark , Cris Kamperschroer , Adam Root , Andrea Hooper , Xiaoying Chen

Pharmacologic Properties and Preclinical Activity of Sasanlimab, A High-affinity Engineered Anti-Human PD-1 Antibody.

Molecular cancer therapeutics

Avec: Amir A Al-Khami , Sawsan Youssef , Yasmina Abdiche , HoangKim Nguyen , Joyce Chou , Christopher R Kimberlin , Sherman M Chin , Cris Kamperschroer , Bart Jessen , Brent Kern , Natalija Budimir , Christopher P Dillon , Allison Xu , Jerry D Clark , Jeffrey Chou , Eugenia Kraynov , Arvind Rajpal , John C Lin , Shahram Salek-Ardakani

Nonclinical Investigation of Cytokine Mitigation Strategies for T-cell-Engaging Bispecifics in the Cynomolgus Macaque.

Journal of immunotherapy (Hagerstown, Md. : 1997)

Avec: Cris Kamperschroer , Magali Guffroy , Amy Shen , Melba Dokmanovich , Makeida Stubbs , Lynn M O'Donnell

Utilization of lipopolysaccharide challenge in cynomolgus macaques to assess IL-10 receptor antagonism.

Journal of immunotoxicology

Avec: Cris Kamperschroer , Richard Goldstein , Patricia A Schneider , Bing Kuang , Michael D Eisenbraun

Industry experiences with immune-mediated findings in biotherapeutic nonclinical toxicology studies.

Regulatory toxicology and pharmacology : RTP

Avec: Timothy K MacLachlan , Sven Kronenberg , Nikki Marshall , Laura Andrews , Shawn Jay Berens , Frederic Brouta , Birgit Fogal , Wendy Freebern , Danuta Herzyk , Cris Kamperschroer , Andrea Kiessling , Marlowe Schneidkraut , Curtis Maier

A Phase 1 Dose-Escalation Study of PF-06671008, a Bispecific T-Cell-Engaging Therapy Targeting P-Cadherin in Patients With Advanced Solid Tumors.

Frontiers in immunology

Avec: James J Harding , Ignacio Garrido-Laguna , Xiaoying Chen , Cynthia Basu , Afshin Dowlati , Alison Forgie , Andrea T Hooper , Cris Kamperschroer , Steven I Max , Allison Moreau , Megan Shannon , Gilbert Y Wong , David S Hong

Cold Agglutinin Disease in a Rhesus Macaque (

Comparative medicine

Avec: Cris Kamperschroer , Karrie Tartaro , Laurie Goodchild , Chelsea Menke , Ashley Artrip , Harshan Pisharath

Réseau de co-auteurs

Xiaoying Chen 4 collaborations

Alison Betts 2 collaborations

Nahor Haddish-Berhane 2 collaborations

Dhaval K Shah 2 collaborations

Piet H van der Graaf 2 collaborations

Frank Barletta 2 collaborations

Lindsay King 2 collaborations

Tracey Clark 2 collaborations

Adam Root 2 collaborations

Andrea Hooper 2 collaborations

Sherman M Chin 2 collaborations

Bing Kuang 2 collaborations

Arvind Rajpal 2 collaborations

Magali Guffroy 2 collaborations

Hervé Lebrec 2 collaborations

Wendy Freebern 2 collaborations

Siler H Panowski 1 collaboration

Tracy C Kuo 1 collaboration

Yi Zhang 1 collaboration

Amy Chen 1 collaboration

Tao Geng 1 collaboration

Laura Aschenbrenner 1 collaboration

Edward Pascua 1 collaboration

Wei Chen 1 collaboration

Kathy Delaria 1 collaboration

Santiago Farias 1 collaboration

Marjorie Bateman 1 collaboration

Russell G Dushin 1 collaboration

Thomas J Van Blarcom 1 collaboration

Yik Andy Yeung 1 collaboration

Kevin C Lindquist 1 collaboration

Allison G Chunyk 1 collaboration

Bora Han 1 collaboration

Michael Mirsky 1 collaboration

Ingrid Pardo 1 collaboration

Bernard Buetow 1 collaboration

Thomas G Martin 1 collaboration

Jeffrey L Wolf 1 collaboration

David Shelton 1 collaboration

Pavel Strop 1 collaboration

Javier Chaparro-Riggers 1 collaboration

Barbra J Sasu 1 collaboration

Gilbert Wong 1 collaboration

Dawei Xuan 1 collaboration

Divya Mathur 1 collaboration

Adam R Root 1 collaboration

Bozena Bugaj-Gaweda 1 collaboration

Stephanie Bisulco 1 collaboration

Xingzhi Tan 1 collaboration

Wei Fang 1 collaboration

Jessica C Kearney 1 collaboration

Justin Lucas 1 collaboration

Jonathan Golas 1 collaboration

Cynthia M Rohde 1 collaboration

Chad Stevens 1 collaboration

Kerry Kelleher 1 collaboration

Rosemary F Lawrence-Henderson 1 collaboration

Erik Upeslacis 1 collaboration

Johnny Yao 1 collaboration

Jatin Narula 1 collaboration

Edward R LaVallie 1 collaboration

Diane R Fernandez 1 collaboration

Bernard S Buetow 1 collaboration

Edward Rosfjord 1 collaboration

Laird Bloom 1 collaboration

Lindsay E King 1 collaboration

Lioudmila Tchistiakova 1 collaboration

Anhco Nguyen 1 collaboration

Puja Sapra 1 collaboration

Jacintha Shenton 1 collaboration

John K Leighton 1 collaboration

Paul A Moore 1 collaboration

Oliver Thomas 1 collaboration

Brendon Frank 1 collaboration

Caroline Genell 1 collaboration

Shermaine Mitchell-Ryan 1 collaboration

Brigitte Molinier 1 collaboration

Courtni Newsome 1 collaboration

Marie-Soleil Piche 1 collaboration

Daniel Weinstock 1 collaboration

Mark Collinge 1 collaboration

Daniel Rubio 1 collaboration

Amir A Al-Khami 1 collaboration

Sawsan Youssef 1 collaboration

Yasmina Abdiche 1 collaboration

HoangKim Nguyen 1 collaboration

Joyce Chou 1 collaboration

Christopher R Kimberlin 1 collaboration

Bart Jessen 1 collaboration

Brent Kern 1 collaboration

Natalija Budimir 1 collaboration

Christopher P Dillon 1 collaboration

Allison Xu 1 collaboration

Jerry D Clark 1 collaboration

Jeffrey Chou 1 collaboration

Eugenia Kraynov 1 collaboration

John C Lin 1 collaboration

Shahram Salek-Ardakani 1 collaboration

Amy Shen 1 collaboration

Melba Dokmanovich 1 collaboration

Makeida Stubbs 1 collaboration

Lynn M O'Donnell 1 collaboration

Richard Goldstein 1 collaboration

Patricia A Schneider 1 collaboration

Michael D Eisenbraun 1 collaboration

Timothy K MacLachlan 1 collaboration

Sven Kronenberg 1 collaboration

Nikki Marshall 1 collaboration

Laura Andrews 1 collaboration

Shawn Jay Berens 1 collaboration

Frederic Brouta 1 collaboration

Birgit Fogal 1 collaboration

Danuta Herzyk 1 collaboration

Andrea Kiessling 1 collaboration

Marlowe Schneidkraut 1 collaboration

Curtis Maier 1 collaboration

James J Harding 1 collaboration

Ignacio Garrido-Laguna 1 collaboration

Cynthia Basu 1 collaboration

Afshin Dowlati 1 collaboration

Alison Forgie 1 collaboration

Andrea T Hooper 1 collaboration

Steven I Max 1 collaboration

Allison Moreau 1 collaboration

Megan Shannon 1 collaboration

Gilbert Y Wong 1 collaboration

David S Hong 1 collaboration

Karrie Tartaro 1 collaboration

Laurie Goodchild 1 collaboration

Chelsea Menke 1 collaboration

Ashley Artrip 1 collaboration

Harshan Pisharath 1 collaboration