Costantinos Koumenis

Publications (53)

The PKR-Like Endoplasmic Reticulum Kinase Promotes the Dissemination of Myc-Induced Leukemic Cells.

Molecular cancer research : MCR
Avec: Jun Gui , Kanstantsin V Katlinski , Constantinos Koumenis , J Alan Diehl , Serge Y Fuchs

Design and commissioning of an image-guided small animal radiation platform and quality assurance protocol for integrated proton and x-ray radiobiology research.

Physics in medicine and biology
Avec: Michele M Kim , Peyton Irmen , Khayrullo Shoniyozov , Ioannis I Verginadis , Keith A Cengel , Costantinos Koumenis , James M Metz , Lei Dong , Eric S Diffenderfer

Precision Cardio-Oncology.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine
Avec: Alexandra D Dreyfuss , Paco E Bravo , Constantinos Koumenis , Bonnie Ky

Wnt-mediated endothelial transformation into mesenchymal stem cell-like cells induces chemoresistance in glioblastoma.

Science translational medicine
Avec: Menggui Huang , Duo Zhang , Janet Y Wu , Kun Xing , Eujin Yeo , Chunsheng Li , Lin Zhang , Eric Holland , Lutian Yao , Ling Qin , Zev A Binder , Donald M O'Rourke , Steven Brem , Constantinos Koumenis , Yanqing Gong , Yi Fan

Intercellular pathways of cancer treatment-related cardiotoxicity and their therapeutic implications: The paradigm of radiotherapy.

Pharmacology & therapeutics
Avec: Stella Logotheti , Athanasia Pavlopoulou , Hamid Khoshfekr Rudsari , Anne-Marie Galow , Yağmur Kafali , Efthymios Kyrodimos , Aris I Giotakis , Stephan Marquardt , Anastasia Velalopoulou , Ioannis I Verginadis , Constantinos Koumenis , Thorsten Stiewe , Jerome Zoidakis , Ilangko Balasingham , Robert David , Alexandros G Georgakilas

Loss of AID exacerbates the malignant progression of CLL.

Leukemia
Avec: Avery C Lee , Sai Ravi Pingali , Javier A Pinilla-Ibarz , Michael L Atchison , Constantinos Koumenis , Yair Argon , Andrei Thomas-Tikhonenko , Carl De Trez , Chih-Chi Andrew Hu , Chih-Hang Anthony Tang

Proton FLASH radiotherapy ameliorates radiation-induced salivary gland dysfunction and oral mucositis and increases survival in a mouse model of head and neck cancer.

Molecular cancer therapeutics
Avec: Priyanka Chowdhury , Anastasia Velalopoulou , Ioannis I Verginadis , George Morcos , Phoebe E Loo , Michele M Kim , Seyyedeh Azar Oliaei Motlagh , Khayrullo Shoniyozov , Eric S Diffenderfer , Emilio A Ocampo , Mary Putt , Charles-Antoine Assenmacher , Enrico Radaelli , Jiawei Lu , Ling Qin , Hengxi Liu , Nektaria Maria Leli , Swati Girdhani , Nicolas Denef , Francois Vander Stappen , Keith A Cengel , Theresa M Busch , James M Metz , Lei Dong , Alexander Lin , Constantinos Koumenis

Combination of CHEK1/2 inhibition and ionizing radiation results in abscopal tumor response through increased micronuclei formation.

Oncogene
Avec: Hann-Hsiang Chao , Ilias V Karagounis , Christoforos Thomas , Noëlle B François , Andrea Facciabene , Constantinos Koumenis , Amit Maity

Regulation of autophagy by canonical and non-canonical ER stress responses.

Seminars in cancer biology
Avec: Monika Bhardwaj , Nektaria Maria Leli , Constantinos Koumenis , Ravi K Amaravadi

LGM2605 Reduces Space Radiation-Induced NLRP3 Inflammasome Activation and Damage in In Vitro Lung Vascular Networks.

International journal of molecular sciences
Avec: Shampa Chatterjee , Ralph A Pietrofesa , Kyewon Park , Jian-Qin Tao , Alejandro Carabe-Fernandez , Abigail T Berman , Constantinos Koumenis , Thais Sielecki , Melpo Christofidou-Solomidou

Interleukin 6 Signaling Blockade Exacerbates Acute and Late Injury From Focal Intestinal Irradiation.

International journal of radiation oncology, biology, physics
Avec: Brett I Bell , Sravya Koduri , Carlo Salas Salinas , James Monslow , Ellen Puré , Edgar Ben-Josef , Constantinos Koumenis , Ioannis I Verginadis

Characterization of a high-resolution 2D transmission ion chamber for independent validation of proton pencil beam scanning of conventional and FLASH dose delivery.

Medical physics
Avec: Wei Zou , Eric S Diffenderfer , Kan Ota , Paul Boisseau , Michele M Kim , Yongliang Cai , Stephen M Avery , David J Carlson , Rodney D Wiersma , Alexander Lin , Constantinos Koumenis , Keith A Cengel , James M Metz , Lei Dong , Boonkeng K Teo

A Novel Mouse Model of Radiation-Induced Cardiac Injury Reveals Biological and Radiological Biomarkers of Cardiac Dysfunction with Potential Clinical Relevance.

Clinical cancer research : an official journal of the American Association for Cancer Research
Avec: Alexandra D Dreyfuss , Denisa Goia , Khayrullo Shoniyozov , Swapnil V Shewale , Anastasia Velalopoulou , Susan Mazzoni , Harris Avgousti , Scott D Metzler , Paco E Bravo , Steven J Feigenberg , Bonnie Ky , Ioannis I Verginadis , Constantinos Koumenis

FLASH Proton Radiotherapy Spares Normal Epithelial and Mesenchymal Tissues While Preserving Sarcoma Response.

Cancer research
Avec: Anastasia Velalopoulou , Ilias V Karagounis , Gwendolyn M Cramer , Michele M Kim , Giorgos Skoufos , Denisa Goia , Sarah Hagan , Ioannis I Verginadis , Khayrullo Shoniyozov , June Chiango , Michelle Cerullo , Kelley Varner , Lutian Yao , Ling Qin , Artemis G Hatzigeorgiou , Andy J Minn , Mary Putt , Matthew Lanza , Charles-Antoine Assenmacher , Enrico Radaelli , Jennifer Huck , Eric Diffenderfer , Lei Dong , James Metz , Constantinos Koumenis , Keith A Cengel , Amit Maity , Theresa M Busch

PHGDH-mediated endothelial metabolism drives glioblastoma resistance to chimeric antigen receptor T cell immunotherapy.

Cell metabolism
Avec: Duo Zhang , Albert M Li , Guanghui Hu , Menggui Huang , Fan Yang , Lin Zhang , Kathryn E Wellen , Xiaowei Xu , Crystal S Conn , Wei Zou , Mark Kahn , Seth D Rhoades , Aalim M Weljie , Serge Y Fuchs , Nduka Amankulor , Daniel Yoshor , Jiangbin Ye , Constantinos Koumenis , Yanqing Gong , Yi Fan

Targeting stress induction of GRP78 by cardiac glycoside oleandrin dually suppresses cancer and COVID-19.

Cell & bioscience
Avec: Dat P Ha , Woo-Jin Shin , Ze Liu , Michael E Doche , Roy Lau , Nektaria Maria Leli , Crystal S Conn , Mariangela Russo , Annalisa Lorenzato , Constantinos Koumenis , Min Yu , Shannon M Mumenthaler , Amy S Lee

ER Translocation of the MAPK Pathway Drives Therapy Resistance in BRAF-Mutant Melanoma.

Cancer discovery
Avec: Rani Ojha , Nektaria M Leli , Angelique Onorati , Shengfu Piao , Ioannis I Verginadis , Feven Tameire , Vito W Rebecca , Cynthia I Chude , Sengottuvelan Murugan , Colin Fennelly , Estela Noguera-Ortega , Charleen T Chu , Shujing Liu , Xiaowei Xu , Clemens Krepler , Min Xiao , Wei Xu , Zhi Wei , Dennie T Frederick , Genevieve Boland , Tara C Mitchell , Giorgos C Karakousis , Lynn M Schuchter , Keith T Flaherty , Gao Zhang , Meenhard Herlyn , Constantinos Koumenis , Ravi K Amaravadi

Clinical measures, radiomics, and genomics offer synergistic value in AI-based prediction of overall survival in patients with glioblastoma.

Scientific reports
Avec: Anahita Fathi Kazerooni , Sanjay Saxena , Erik Toorens , Danni Tu , Vishnu Bashyam , Hamed Akbari , Elizabeth Mamourian , Chiharu Sako , Costas Koumenis , Ioannis Verginadis , Ragini Verma , Russell T Shinohara , Arati S Desai , Robert A Lustig , Steven Brem , Suyash Mohan , Stephen J Bagley , Tapan Ganguly , Donald M O'Rourke , Spyridon Bakas , MacLean P Nasrallah , Christos Davatzikos

Activation of p38α stress-activated protein kinase drives the formation of the pre-metastatic niche in the lungs.

Nature cancer
Avec: Jun Gui , Farima Zahedi , Angelica Ortiz , Christina Cho , Kanstantsin V Katlinski , Kevin Alicea-Torres , Jinyang Li , Leslie Todd , Hongru Zhang , Daniel P Beiting , Cindy Sander , John M Kirkwood , Bryan E Snow , Andrew C Wakeham , Tak W Mak , J Alan Diehl , Constantinos Koumenis , Sandra W Ryeom , Ben Z Stanger , Ellen Puré , Dmitry I Gabrilovich , Serge Y Fuchs

Shining a FLASHlight on Ultrahigh Dose-Rate Radiation and Possible Late Toxicity.

Clinical cancer research : an official journal of the American Association for Cancer Research
Avec: Amit Maity , Constantinos Koumenis

Integrating imaging and genomic data for the discovery of distinct glioblastoma subtypes: a joint learning approach.

Scientific reports
Avec: Jun Guo , Anahita Fathi Kazerooni , Erik Toorens , Hamed Akbari , Fanyang Yu , Chiharu Sako , Elizabeth Mamourian , Russell T Shinohara , Constantinos Koumenis , Stephen J Bagley , Jennifer J D Morrissette , Zev A Binder , Steven Brem , Suyash Mohan , Robert A Lustig , Donald M O'Rourke , Tapan Ganguly , Spyridon Bakas , MacLean P Nasrallah , Christos Davatzikos

A phenomenological model of proton FLASH oxygen depletion effects depending on tissue vasculature and oxygen supply.

Frontiers in oncology
Avec: Wei Zou , Haram Kim , Eric S Diffenderfer , David J Carlson , Cameron J Koch , Ying Xiao , BoonKeng K Teo , Michele M Kim , James M Metz , Yi Fan , Amit Maity , Costas Koumenis , Theresa M Busch , Rodney Wiersma , Keith A Cengel , Lei Dong

miR-217 regulates normal and tumor cell fate following induction of Endoplasmic Reticulum Stress.

Molecular cancer research : MCR
Avec: Neekkan Dey , Constantinos Koumenis , Davide Ruggero , Serge Y Fuchs , J Alan Diehl

Early Inflammation and Interferon Signaling Direct Enhanced Intestinal Crypt Regeneration after Proton FLASH Radiotherapy.

bioRxiv : the preprint server for biology
Avec: Tristan L Lim , Clara Morral , Ioannis I Verginadis , Kyle Kim , Leo Luo , Caitlin J Foley , Michele M Kim , Ning Li , Benjamin Yoshor , Kizito Njah , Mary Putt , Seyyedeh Azar Oliaei Motlagh , Anastasia Velalopoulou , Priyanka Chowdhury , Sandra Bicher , Denisa Goia , Christopher J Lengner , Jeffery L Wrana , Constantinos Koumenis , Andy J Minn

Modified C-type natriuretic peptide normalizes tumor vasculature, reinvigorates antitumor immunity, and improves solid tumor therapies.

Science translational medicine
Avec: Zhen Lu , Ioannis Verginadis , Motofumi Kumazoe , Gerardo M Castillo , Yao Yao , Rebecca E Guerra , Sandra Bicher , Menghao You , George McClung , Rong Qiu , Zebin Xiao , Zhen Miao , Subin S George , Daniel P Beiting , Takashi Nojiri , Yasutake Tanaka , Yoshinori Fujimura , Hiroaki Onda , Yui Hatakeyama , Akiko Nishimoto-Ashfield , Katrina Bykova , Wei Guo , Yi Fan , Nikolay M Buynov , J Alan Diehl , Ben Z Stanger , Hirofumi Tachibana , Terence P Gade , Ellen Puré , Constantinos Koumenis , Elijah M Bolotin , Serge Y Fuchs

Gut microbiota modulate dendritic cell antigen presentation and radiotherapy-induced antitumor immune response.

The Journal of clinical investigation
Avec: Mireia Uribe-Herranz , Stavros Rafail , Silvia Beghi , Luis Gil-de-Gómez , Ioannis Verginadis , Kyle Bittinger , Sergey Pustylnikov , Stefano Pierini , Renzo Perales-Linares , Ian A Blair , Clementina A Mesaros , Nathaniel W Snyder , Frederic Bushman , Constantinos Koumenis , Andrea Facciabene

ATF4 couples MYC-dependent translational activity to bioenergetic demands during tumour progression.

Nature cell biology
Avec: Feven Tameire , Ioannis I Verginadis , Nektaria Maria Leli , Christine Polte , Crystal S Conn , Rani Ojha , Carlo Salas Salinas , Frank Chinga , Alexandra M Monroy , Weixuan Fu , Paul Wang , Andrew Kossenkov , Jiangbin Ye , Ravi K Amaravadi , Zoya Ignatova , Serge Y Fuchs , J Alan Diehl , Davide Ruggero , Constantinos Koumenis

Current delivery limitations of proton PBS for FLASH.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
Avec: Wei Zou , Eric S Diffenderfer , Keith A Cengel , Michele M Kim , Steve Avery , Joshua Konzer , Yongliang Cai , Paul Boisseu , Kan Ota , Lingshu Yin , Rodney Wiersma , David J Carlson , Yi Fan , Theresa M Busch , Costas Koumenis , Alexander Lin , James M Metz , BoonKeng K Teo , Lei Dong

Key biological mechanisms involved in high-LET radiation therapies with a focus on DNA damage and repair.

Expert reviews in molecular medicine
Avec: Zacharenia Nikitaki , Anastasia Velalopoulou , Vassiliki Zanni , Ioanna Tremi , Sophia Havaki , Michael Kokkoris , Vassilis G Gorgoulis , Constantinos Koumenis , Alexandros G Georgakilas

Targeting PARP11 to avert immunosuppression and improve CAR T therapy in solid tumors.

Nature cancer
Avec: Hongru Zhang , Pengfei Yu , Vivek S Tomar , Xiangjie Chen , Matthew J Atherton , Zhen Lu , Hong-Guang Zhang , Shifeng Li , Angelica Ortiz , Jun Gui , N Adrian Leu , Fangxue Yan , Andres Blanco , Mirella L Meyer-Ficca , Ralph G Meyer , Daniel P Beiting , Jinyang Li , Selene Nunez-Cruz , Roddy S O'Connor , Lexus R Johnson , Andy J Minn , Subin S George , Constantinos Koumenis , J Alan Diehl , Michael C Milone , Hui Zheng , Serge Y Fuchs

p53 promotes revival stem cells in the regenerating intestine after severe radiation injury.

bioRxiv : the preprint server for biology
Avec: Clara Morral , Arshad Ayyaz , Hsuan-Cheng Kuo , Mardi Fink , Ioannis Verginadis , Andrea R Daniel , Danielle N Burner , Lucy M Driver , Sloane Satow , Stephanie Hasapis , Reem Ghinnagow , Lixia Luo , Yan Ma , Laura D Attardi , Costas Koumenis , Andy J Minn , Jeffrey L Wrana , Chang-Lung Lee , David G Kirsch

Parkin Deficiency Suppresses Antigen Presentation to Promote Tumor Immune Evasion and Immunotherapy Resistance.

Cancer research
Avec: Renzo Perales-Linares , Nektaria Maria Leli , Hesham Mohei , Silvia Beghi , Osvaldo D Rivera , Nektarios Kostopoulos , Andrea Giglio , Subin S George , Mireia Uribe-Herranz , Francesca Costabile , Stefano Pierini , Sergei Pustylnikov , Giorgos Skoufos , Yoseph Barash , Artemis G Hatzigeorgiou , Constantinos Koumenis , Amit Maity , Michael T Lotze , Andrea Facciabene

An immunosuppressive vascular niche drives macrophage polarization and immunotherapy resistance in glioblastoma.

Science advances
Avec: Fan Yang , Md Naushad Akhtar , Duo Zhang , Rakan El-Mayta , Junyoung Shin , Jay F Dorsey , Lin Zhang , Xiaowei Xu , Wei Guo , Stephen J Bagley , Serge Y Fuchs , Constantinos Koumenis , Justin D Lathia , Michael J Mitchell , Yanqing Gong , Yi Fan

FLASH proton radiotherapy mitigates inflammatory and fibrotic pathways and preserves cardiac function in a preclinical mouse model of radiation-induced heart disease.

International journal of radiation oncology, biology, physics
Avec: Kyle Kim , Michele M Kim , Giorgos Skoufos , Eric S Diffenderfer , Seyyedeh Azar Oliaei Motlagh , Michail Kokkorakis , Ilektra Koliaki , George Morcos , Khayrullo Shoniyozov , Joanna Griffin , Artemis G Hatzigeorgiou , James M Metz , Alexander Lin , Steven J Feigenberg , Keith A Cengel , Bonnie Ky , Constantinos Koumenis , Ioannis I Verginadis

The ISR downstream target ATF4 represses long-term memory in a cell type-specific manner.

Proceedings of the National Academy of Sciences of the United States of America
Avec: Niaz Mahmood , Jung-Hyun Choi , Pei You Wu , Sean W Dooling , Trent A Watkins , Ziying Huang , Jesse Lipman , Hanjie Zhao , Anqi Yang , Jake Silversmith , Yanis Inglebert , Constantinos Koumenis , Vijendra Sharma , Jean-Claude Lacaille , Wayne S Sossin , Arkady Khoutorsky , R Anne McKinney , Mauro Costa-Mattioli , Nahum Sonenberg

FLASH proton reirradiation, with or without hypofractionation, mitigates chronic toxicity in the normal murine intestine, skin, and bone.

bioRxiv : the preprint server for biology
Avec: Ioannis I Verginadis , Anastasia Velalopoulou , Michele M Kim , Kyle Kim , Ioannis Paraskevaidis , Brett Bell , Seyyedeh Azar Oliaei Motlagh , Antoneta Karaj , Esha Banerjee , Giovanni Finesso , Charles-Antoine Assenmacher , Enrico Radaelli , Jiawei Lu , Yuewei Lin , Mary E Putt , Eric S Diffenderfer , Chandan Guha , Ling Qin , James M Metz , Amit Maity , Keith A Cengel , Constantinos Koumenis , Theresa M Busch

Author Correction: ATF4 couples MYC-dependent translational activity to bioenergetic demands during tumour progression.

Nature cell biology
Avec: Feven Tameire , Ioannis I Verginadis , Nektaria Maria Leli , Christine Polte , Crystal S Conn , Rani Ojha , Carlo Salas Salinas , Frank Chinga , Alexandra M Monroy , Weixuan Fu , Paul Wang , Andrew Kossenkov , Jiangbin Ye , Ravi K Amaravadi , Zoya Ignatova , Serge Y Fuchs , J Alan Diehl , Davide Ruggero , Constantinos Koumenis

An Interferon-Driven Oxysterol-Based Defense against Tumor-Derived Extracellular Vesicles.

Cancer cell
Avec: Angelica Ortiz , Jun Gui , Farima Zahedi , Pengfei Yu , Christina Cho , Sabyasachi Bhattacharya , Christopher J Carbone , Qiujing Yu , Kanstantsin V Katlinski , Yuliya V Katlinskaya , Simran Handa , Victor Haas , Susan W Volk , Angela K Brice , Kim Wals , Nicholas J Matheson , Robin Antrobus , Sonja Ludwig , Theresa L Whiteside , Cindy Sander , Ahmad A Tarhini , John M Kirkwood , Paul J Lehner , Wei Guo , Hallgeir Rui , Andy J Minn , Constantinos Koumenis , J Alan Diehl , Serge Y Fuchs

Design, Implementation, and in Vivo Validation of a Novel Proton FLASH Radiation Therapy System.

International journal of radiation oncology, biology, physics
Avec: Eric S Diffenderfer , Ioannis I Verginadis , Michele M Kim , Khayrullo Shoniyozov , Anastasia Velalopoulou , Denisa Goia , Mary Putt , Sarah Hagan , Stephen Avery , Kevin Teo , Wei Zou , Alexander Lin , Samuel Swisher-McClure , Cameron Koch , Ann R Kennedy , Andy Minn , Amit Maity , Theresa M Busch , Lei Dong , Costas Koumenis , James Metz , Keith A Cengel

Combination of vasculature targeting, hypofractionated radiotherapy, and immune checkpoint inhibitor elicits potent antitumor immune response and blocks tumor progression.

Journal for immunotherapy of cancer
Avec: Stefano Pierini , Abhishek Mishra , Renzo Perales-Linares , Mireia Uribe-Herranz , Silvia Beghi , Andrea Giglio , Sergei Pustylnikov , Francesca Costabile , Stavros Rafail , Augusto Amici , John G Facciponte , Costantinos Koumenis , Andrea Facciabene

Regulation of intercellular biomolecule transfer-driven tumor angiogenesis and responses to anticancer therapies.

The Journal of clinical investigation
Avec: Zhen Lu , Angelica Ortiz , Ioannis I Verginadis , Amy R Peck , Farima Zahedi , Christina Cho , Pengfei Yu , Rachel M DeRita , Hongru Zhang , Ryan Kubanoff , Yunguang Sun , Andrew T Yaspan , Elise Krespan , Daniel P Beiting , Enrico Radaelli , Sandra W Ryeom , J Alan Diehl , Hallgeir Rui , Constantinos Koumenis , Serge Y Fuchs

Estrogen Receptor β-Mediated Inhibition of Actin-Based Cell Migration Suppresses Metastasis of Inflammatory Breast Cancer.

Cancer research
Avec: Christoforos Thomas , Ilias V Karagounis , Ratnesh K Srivastava , Nicholas Vrettos , Fotis Nikolos , Noëlle Francois , Menggui Huang , Siliang Gong , Qi Long , Sushil Kumar , Constantinos Koumenis , Savitri Krishnamurthy , Naoto T Ueno , Rumela Chakrabarti , Amit Maity

Comparison of FLASH Proton Entrance and the Spread-Out Bragg Peak Dose Regions in the Sparing of Mouse Intestinal Crypts and in a Pancreatic Tumor Model.

Cancers
Avec: Michele M Kim , Ioannis I Verginadis , Denisa Goia , Allison Haertter , Khayrullo Shoniyozov , Wei Zou , Amit Maity , Theresa M Busch , James M Metz , Keith A Cengel , Lei Dong , Costas Koumenis , Eric S Diffenderfer

Loss of p19Arf promotes fibroblast survival during leucine deprivation.

Biology open
Avec: Kerry C Roby , Allyson Lieberman , Bang-Jin Kim , Nicole Zaragoza Rodríguez , Jessica M Posimo , Tiffany Tsang , Ioannis I Verginadis , Ellen Puré , Donita C Brady , Constantinos Koumenis , Sandra Ryeom

A stromal Integrated Stress Response activates perivascular cancer-associated fibroblasts to drive angiogenesis and tumour progression.

Nature cell biology
Avec: Ioannis I Verginadis , Harris Avgousti , James Monslow , Giorgos Skoufos , Frank Chinga , Kyle Kim , Nektaria Maria Leli , Ilias V Karagounis , Brett I Bell , Anastasia Velalopoulou , Carlo Salas Salinas , Victoria S Wu , Yang Li , Jiangbin Ye , David A Scott , Andrei L Osterman , Arjun Sengupta , Aalim Weljie , Menggui Huang , Duo Zhang , Yi Fan , Enrico Radaelli , John W Tobias , Florian Rambow , Panagiotis Karras , Jean-Christophe Marine , Xiaowei Xu , Artemis G Hatzigeorgiou , Sandra Ryeom , J Alan Diehl , Serge Y Fuchs , Ellen Puré , Constantinos Koumenis

p53 promotes revival stem cells in the regenerating intestine after severe radiation injury.

Nature communications
Avec: Clara Morral , Arshad Ayyaz , Hsuan-Cheng Kuo , Mardi Fink , Ioannis I Verginadis , Andrea R Daniel , Danielle N Burner , Lucy M Driver , Sloane Satow , Stephanie Hasapis , Reem Ghinnagow , Lixia Luo , Yan Ma , Laura D Attardi , Constantinos Koumenis , Andy J Minn , Jeffrey L Wrana , Chang-Lung Lee , David G Kirsch

ATF3 and CH25H regulate effector trogocytosis and anti-tumor activities of endogenous and immunotherapeutic cytotoxic T lymphocytes.

Cell metabolism
Avec: Zhen Lu , Noreen McBrearty , Jinyun Chen , Vivek S Tomar , Hongru Zhang , Gianluca De Rosa , Aiwen Tan , Aalim M Weljie , Daniel P Beiting , Zhen Miao , Subin S George , Allison Berger , Gurpanna Saggu , J Alan Diehl , Constantinos Koumenis , Serge Y Fuchs

Induction of the activating transcription factor-4 in the intratumoral CD8+ T cells sustains their viability and anti-tumor activities.

Cancer immunology, immunotherapy : CII
Avec: Zhen Lu , Eun-Ah Bae , Ioannis I Verginadis , Hongru Zhang , Christina Cho , Noreen McBrearty , Subin S George , J Alan Diehl , Constantinos Koumenis , Linda M Bradley , Serge Y Fuchs

Roadmap for precision preclinical x-ray radiation studies.

Physics in medicine and biology
Avec: Frank Verhaegen , Karl T Butterworth , Anthony J Chalmers , Rob P Coppes , Dirk de Ruysscher , Sophie Dobiasch , John D Fenwick , Patrick V Granton , Stefan H J Heijmans , Mark A Hill , Constantinos Koumenis , Kirsten Lauber , Brian Marples , Katia Parodi , Lucas C G G Persoon , Nick Staut , Anna Subiel , Rianne D W Vaes , Stefan van Hoof , Ioannis L Verginadis , Jan J Wilkens , Kaye J Williams , George D Wilson , Ludwig J Dubois

A Novel Ubiquitin Complex Regulates Aneuploid Epithelial Tumors by Moderating an Integrated Stress Response.

Cancer discovery
Avec: Nektaria Maria Leli , Constantinos Koumenis

Updates on radiotherapy-immunotherapy combinations: Proceedings of 6

Oncoimmunology
Avec: Fabiana Gregucci , Sheila Spada , Mary Helen Barcellos-Hoff , Nina Bhardwaj , Charleen Chan Wah Hak , Alba Fiorentino , Chandan Guha , Monica L Guzman , Kevin Harrington , Fernanda G Herrera , Jamie Honeychurch , Theodore Hong , Lorea Iturri , Elisabeth Jaffee , Sana D Karam , Simon R V Knott , Constantinos Koumenis , David Lyden , Ariel E Marciscano , Alan Melcher , Michele Mondini , Anna Mondino , Zachary S Morris , Sean Pitroda , Sergio A Quezada , Laura Santambrogio , Stephen Shiao , John Stagg , Irma Telarovic , Robert Timmerman , Marie-Catherine Vozenin , Ralph Weichselbaum , James Welsh , Anna Wilkins , Chris Xu , Roberta Zappasodi , Weiping Zou , Alexandre Bobard , Sandra Demaria , Lorenzo Galluzzi , Eric Deutsch , Silvia C Formenti

Local Radiation Enhances Systemic CAR T Cell Efficacy by Augmenting Antigen Cross-Presentation and T-cell Infiltration.

Blood advances
Avec: Nektarios Kostopoulos , Francesca Costabile , Elisavet Krimitza , Silvia Beghi , Denisa Goia , Renzo Perales-Linares , George Thyfronitis , Michael J LaRiviere , Elise A Chong , Stephen J Schuster , Amit Maity , Constantinos Koumenis , John P Plastaras , Andrea Facciabene

Proton radiation boosts the efficacy of mesothelin-targeting chimeric antigen receptor T cell therapy in pancreatic cancer.

Proceedings of the National Academy of Sciences of the United States of America
Avec: Uri Amit , Ugur Uslu , Ioannis I Verginadis , Michele M Kim , Seyyedeh Azar Oliaei Motlagh , Eric S Diffenderfer , Charles-Antoine Assenmacher , Sandra Bicher , Sebastian J Atoche , Edgar Ben-Josef , Regina M Young , Carl H June , Constantinos Koumenis

Réseau de co-auteurs

Constantinos Koumenis 45 collaborations
Ioannis I Verginadis 20 collaborations
Serge Y Fuchs 14 collaborations
J Alan Diehl 12 collaborations
Michele M Kim 12 collaborations
Keith A Cengel 10 collaborations
Eric S Diffenderfer 10 collaborations
Amit Maity 10 collaborations
Anastasia Velalopoulou 9 collaborations
James M Metz 8 collaborations
Lei Dong 8 collaborations
Nektaria Maria Leli 8 collaborations
Khayrullo Shoniyozov 7 collaborations
Yi Fan 7 collaborations
Theresa M Busch 7 collaborations
Wei Zou 6 collaborations
Denisa Goia 6 collaborations
Andy J Minn 6 collaborations
Costas Koumenis 6 collaborations
Seyyedeh Azar Oliaei Motlagh 5 collaborations
Enrico Radaelli 5 collaborations
Alexander Lin 5 collaborations
Andrea Facciabene 5 collaborations
Ellen Puré 5 collaborations
Hongru Zhang 5 collaborations
Daniel P Beiting 5 collaborations
Zhen Lu 5 collaborations
Subin S George 5 collaborations
Jun Gui 4 collaborations
Menggui Huang 4 collaborations
Duo Zhang 4 collaborations
Ling Qin 4 collaborations
Mary Putt 4 collaborations
Charles-Antoine Assenmacher 4 collaborations
Ilias V Karagounis 4 collaborations
Ravi K Amaravadi 4 collaborations
Carlo Salas Salinas 4 collaborations
Giorgos Skoufos 4 collaborations
Artemis G Hatzigeorgiou 4 collaborations
Xiaowei Xu 4 collaborations
Crystal S Conn 4 collaborations
Jiangbin Ye 4 collaborations
Ioannis Verginadis 4 collaborations
Angelica Ortiz 4 collaborations
Christina Cho 4 collaborations
Kyle Kim 4 collaborations
Silvia Beghi 4 collaborations
Renzo Perales-Linares 4 collaborations
Kanstantsin V Katlinski 3 collaborations
Bonnie Ky 3 collaborations
Lin Zhang 3 collaborations
Donald M O'Rourke 3 collaborations
Steven Brem 3 collaborations
Yanqing Gong 3 collaborations
David J Carlson 3 collaborations
Rani Ojha 3 collaborations
Feven Tameire 3 collaborations
Stephen J Bagley 3 collaborations
Farima Zahedi 3 collaborations
Davide Ruggero 3 collaborations
Clara Morral 3 collaborations
Sandra Bicher 3 collaborations
Wei Guo 3 collaborations
Mireia Uribe-Herranz 3 collaborations
Stefano Pierini 3 collaborations
Frank Chinga 3 collaborations
Pengfei Yu 3 collaborations
Francesca Costabile 3 collaborations
Alexandra D Dreyfuss 2 collaborations
Paco E Bravo 2 collaborations
Lutian Yao 2 collaborations
Zev A Binder 2 collaborations
Alexandros G Georgakilas 2 collaborations
Priyanka Chowdhury 2 collaborations
George Morcos 2 collaborations
Jiawei Lu 2 collaborations
Christoforos Thomas 2 collaborations
Brett I Bell 2 collaborations
James Monslow 2 collaborations
Edgar Ben-Josef 2 collaborations
Kan Ota 2 collaborations
Yongliang Cai 2 collaborations
Harris Avgousti 2 collaborations
Steven J Feigenberg 2 collaborations
Sarah Hagan 2 collaborations
James Metz 2 collaborations
Fan Yang 2 collaborations
Aalim M Weljie 2 collaborations
Anahita Fathi Kazerooni 2 collaborations
Erik Toorens 2 collaborations
Hamed Akbari 2 collaborations
Elizabeth Mamourian 2 collaborations
Chiharu Sako 2 collaborations
Russell T Shinohara 2 collaborations
Robert A Lustig 2 collaborations
Suyash Mohan 2 collaborations
Tapan Ganguly 2 collaborations
Spyridon Bakas 2 collaborations
MacLean P Nasrallah 2 collaborations
Christos Davatzikos 2 collaborations
Jinyang Li 2 collaborations
Cindy Sander 2 collaborations
John M Kirkwood 2 collaborations
Sandra W Ryeom 2 collaborations
Ben Z Stanger 2 collaborations
BoonKeng K Teo 2 collaborations
Rodney Wiersma 2 collaborations
Zhen Miao 2 collaborations
Stavros Rafail 2 collaborations
Christine Polte 2 collaborations
Alexandra M Monroy 2 collaborations
Weixuan Fu 2 collaborations
Paul Wang 2 collaborations
Andrew Kossenkov 2 collaborations
Zoya Ignatova 2 collaborations
Vivek S Tomar 2 collaborations
Arshad Ayyaz 2 collaborations
Hsuan-Cheng Kuo 2 collaborations
Mardi Fink 2 collaborations
Andrea R Daniel 2 collaborations
Danielle N Burner 2 collaborations
Lucy M Driver 2 collaborations
Sloane Satow 2 collaborations
Stephanie Hasapis 2 collaborations
Reem Ghinnagow 2 collaborations
Lixia Luo 2 collaborations
Yan Ma 2 collaborations
Laura D Attardi 2 collaborations
Jeffrey L Wrana 2 collaborations
Chang-Lung Lee 2 collaborations
David G Kirsch 2 collaborations
Nektarios Kostopoulos 2 collaborations
Andrea Giglio 2 collaborations
Sergei Pustylnikov 2 collaborations
Chandan Guha 2 collaborations
Hallgeir Rui 2 collaborations
Sandra Ryeom 2 collaborations
Noreen McBrearty 2 collaborations
Peyton Irmen 1 collaboration
Janet Y Wu 1 collaboration
Kun Xing 1 collaboration
Eujin Yeo 1 collaboration
Chunsheng Li 1 collaboration
Eric Holland 1 collaboration
Stella Logotheti 1 collaboration
Athanasia Pavlopoulou 1 collaboration
Hamid Khoshfekr Rudsari 1 collaboration
Anne-Marie Galow 1 collaboration
Yağmur Kafali 1 collaboration
Efthymios Kyrodimos 1 collaboration
Aris I Giotakis 1 collaboration
Stephan Marquardt 1 collaboration
Thorsten Stiewe 1 collaboration
Jerome Zoidakis 1 collaboration
Ilangko Balasingham 1 collaboration
Robert David 1 collaboration
Avery C Lee 1 collaboration
Sai Ravi Pingali 1 collaboration
Javier A Pinilla-Ibarz 1 collaboration
Michael L Atchison 1 collaboration
Yair Argon 1 collaboration
Andrei Thomas-Tikhonenko 1 collaboration
Carl De Trez 1 collaboration
Chih-Chi Andrew Hu 1 collaboration
Chih-Hang Anthony Tang 1 collaboration
Phoebe E Loo 1 collaboration
Emilio A Ocampo 1 collaboration
Hengxi Liu 1 collaboration
Swati Girdhani 1 collaboration
Nicolas Denef 1 collaboration
Francois Vander Stappen 1 collaboration
Hann-Hsiang Chao 1 collaboration
Noëlle B François 1 collaboration
Monika Bhardwaj 1 collaboration
Shampa Chatterjee 1 collaboration
Ralph A Pietrofesa 1 collaboration
Kyewon Park 1 collaboration
Jian-Qin Tao 1 collaboration
Alejandro Carabe-Fernandez 1 collaboration
Abigail T Berman 1 collaboration
Thais Sielecki 1 collaboration
Melpo Christofidou-Solomidou 1 collaboration
Sravya Koduri 1 collaboration
Paul Boisseau 1 collaboration
Stephen M Avery 1 collaboration
Rodney D Wiersma 1 collaboration
Boonkeng K Teo 1 collaboration
Swapnil V Shewale 1 collaboration
Susan Mazzoni 1 collaboration
Scott D Metzler 1 collaboration
Gwendolyn M Cramer 1 collaboration
June Chiango 1 collaboration
Michelle Cerullo 1 collaboration
Kelley Varner 1 collaboration
Matthew Lanza 1 collaboration
Jennifer Huck 1 collaboration
Eric Diffenderfer 1 collaboration
Albert M Li 1 collaboration
Guanghui Hu 1 collaboration
Kathryn E Wellen 1 collaboration
Mark Kahn 1 collaboration
Seth D Rhoades 1 collaboration
Nduka Amankulor 1 collaboration
Daniel Yoshor 1 collaboration
Dat P Ha 1 collaboration
Woo-Jin Shin 1 collaboration
Ze Liu 1 collaboration
Michael E Doche 1 collaboration
Roy Lau 1 collaboration
Mariangela Russo 1 collaboration
Annalisa Lorenzato 1 collaboration
Min Yu 1 collaboration
Shannon M Mumenthaler 1 collaboration
Amy S Lee 1 collaboration
Nektaria M Leli 1 collaboration
Angelique Onorati 1 collaboration
Shengfu Piao 1 collaboration
Vito W Rebecca 1 collaboration
Cynthia I Chude 1 collaboration
Sengottuvelan Murugan 1 collaboration
Colin Fennelly 1 collaboration
Estela Noguera-Ortega 1 collaboration
Charleen T Chu 1 collaboration
Shujing Liu 1 collaboration
Clemens Krepler 1 collaboration
Min Xiao 1 collaboration
Wei Xu 1 collaboration
Zhi Wei 1 collaboration
Dennie T Frederick 1 collaboration
Genevieve Boland 1 collaboration
Tara C Mitchell 1 collaboration
Giorgos C Karakousis 1 collaboration
Lynn M Schuchter 1 collaboration
Keith T Flaherty 1 collaboration
Gao Zhang 1 collaboration
Meenhard Herlyn 1 collaboration
Sanjay Saxena 1 collaboration
Danni Tu 1 collaboration
Vishnu Bashyam 1 collaboration
Ragini Verma 1 collaboration
Arati S Desai 1 collaboration
Kevin Alicea-Torres 1 collaboration
Leslie Todd 1 collaboration
Bryan E Snow 1 collaboration
Andrew C Wakeham 1 collaboration
Tak W Mak 1 collaboration
Dmitry I Gabrilovich 1 collaboration
Jun Guo 1 collaboration
Fanyang Yu 1 collaboration
Jennifer J D Morrissette 1 collaboration
Haram Kim 1 collaboration
Cameron J Koch 1 collaboration
Ying Xiao 1 collaboration
Neekkan Dey 1 collaboration
Tristan L Lim 1 collaboration
Leo Luo 1 collaboration
Caitlin J Foley 1 collaboration
Ning Li 1 collaboration
Benjamin Yoshor 1 collaboration
Kizito Njah 1 collaboration
Christopher J Lengner 1 collaboration
Jeffery L Wrana 1 collaboration
Motofumi Kumazoe 1 collaboration
Gerardo M Castillo 1 collaboration
Yao Yao 1 collaboration
Rebecca E Guerra 1 collaboration
Menghao You 1 collaboration
George McClung 1 collaboration
Rong Qiu 1 collaboration
Zebin Xiao 1 collaboration
Takashi Nojiri 1 collaboration
Yasutake Tanaka 1 collaboration
Yoshinori Fujimura 1 collaboration
Hiroaki Onda 1 collaboration
Yui Hatakeyama 1 collaboration
Akiko Nishimoto-Ashfield 1 collaboration
Katrina Bykova 1 collaboration
Nikolay M Buynov 1 collaboration
Hirofumi Tachibana 1 collaboration
Terence P Gade 1 collaboration
Elijah M Bolotin 1 collaboration
Luis Gil-de-Gómez 1 collaboration
Kyle Bittinger 1 collaboration
Sergey Pustylnikov 1 collaboration
Ian A Blair 1 collaboration
Clementina A Mesaros 1 collaboration
Nathaniel W Snyder 1 collaboration
Frederic Bushman 1 collaboration
Steve Avery 1 collaboration
Joshua Konzer 1 collaboration
Paul Boisseu 1 collaboration
Lingshu Yin 1 collaboration
Zacharenia Nikitaki 1 collaboration
Vassiliki Zanni 1 collaboration
Ioanna Tremi 1 collaboration
Sophia Havaki 1 collaboration
Michael Kokkoris 1 collaboration
Vassilis G Gorgoulis 1 collaboration
Xiangjie Chen 1 collaboration
Matthew J Atherton 1 collaboration
Hong-Guang Zhang 1 collaboration
Shifeng Li 1 collaboration
N Adrian Leu 1 collaboration
Fangxue Yan 1 collaboration
Andres Blanco 1 collaboration
Mirella L Meyer-Ficca 1 collaboration
Ralph G Meyer 1 collaboration
Selene Nunez-Cruz 1 collaboration
Roddy S O'Connor 1 collaboration
Lexus R Johnson 1 collaboration
Michael C Milone 1 collaboration
Hui Zheng 1 collaboration
Hesham Mohei 1 collaboration
Osvaldo D Rivera 1 collaboration
Yoseph Barash 1 collaboration
Michael T Lotze 1 collaboration
Md Naushad Akhtar 1 collaboration
Rakan El-Mayta 1 collaboration
Junyoung Shin 1 collaboration
Jay F Dorsey 1 collaboration
Justin D Lathia 1 collaboration
Michael J Mitchell 1 collaboration
Michail Kokkorakis 1 collaboration
Ilektra Koliaki 1 collaboration
Joanna Griffin 1 collaboration
Niaz Mahmood 1 collaboration
Jung-Hyun Choi 1 collaboration
Pei You Wu 1 collaboration
Sean W Dooling 1 collaboration
Trent A Watkins 1 collaboration
Ziying Huang 1 collaboration
Jesse Lipman 1 collaboration
Hanjie Zhao 1 collaboration
Anqi Yang 1 collaboration
Jake Silversmith 1 collaboration
Yanis Inglebert 1 collaboration
Vijendra Sharma 1 collaboration
Jean-Claude Lacaille 1 collaboration
Wayne S Sossin 1 collaboration
Arkady Khoutorsky 1 collaboration
R Anne McKinney 1 collaboration
Mauro Costa-Mattioli 1 collaboration
Nahum Sonenberg 1 collaboration
Ioannis Paraskevaidis 1 collaboration
Brett Bell 1 collaboration
Antoneta Karaj 1 collaboration
Esha Banerjee 1 collaboration
Giovanni Finesso 1 collaboration
Yuewei Lin 1 collaboration
Mary E Putt 1 collaboration
Sabyasachi Bhattacharya 1 collaboration
Christopher J Carbone 1 collaboration
Qiujing Yu 1 collaboration
Yuliya V Katlinskaya 1 collaboration
Simran Handa 1 collaboration
Victor Haas 1 collaboration
Susan W Volk 1 collaboration
Angela K Brice 1 collaboration
Kim Wals 1 collaboration
Nicholas J Matheson 1 collaboration
Robin Antrobus 1 collaboration
Sonja Ludwig 1 collaboration
Theresa L Whiteside 1 collaboration
Ahmad A Tarhini 1 collaboration
Paul J Lehner 1 collaboration
Stephen Avery 1 collaboration
Kevin Teo 1 collaboration
Samuel Swisher-McClure 1 collaboration
Cameron Koch 1 collaboration
Ann R Kennedy 1 collaboration
Andy Minn 1 collaboration
Abhishek Mishra 1 collaboration
Augusto Amici 1 collaboration
John G Facciponte 1 collaboration
Amy R Peck 1 collaboration
Rachel M DeRita 1 collaboration
Ryan Kubanoff 1 collaboration
Yunguang Sun 1 collaboration
Andrew T Yaspan 1 collaboration
Elise Krespan 1 collaboration
Ratnesh K Srivastava 1 collaboration
Nicholas Vrettos 1 collaboration
Fotis Nikolos 1 collaboration
Noëlle Francois 1 collaboration
Siliang Gong 1 collaboration
Qi Long 1 collaboration
Sushil Kumar 1 collaboration
Savitri Krishnamurthy 1 collaboration
Naoto T Ueno 1 collaboration
Rumela Chakrabarti 1 collaboration
Allison Haertter 1 collaboration
Kerry C Roby 1 collaboration
Allyson Lieberman 1 collaboration
Bang-Jin Kim 1 collaboration
Nicole Zaragoza Rodríguez 1 collaboration
Jessica M Posimo 1 collaboration
Tiffany Tsang 1 collaboration
Donita C Brady 1 collaboration
Victoria S Wu 1 collaboration
Yang Li 1 collaboration
David A Scott 1 collaboration
Andrei L Osterman 1 collaboration
Arjun Sengupta 1 collaboration
Aalim Weljie 1 collaboration
John W Tobias 1 collaboration
Florian Rambow 1 collaboration
Panagiotis Karras 1 collaboration
Jean-Christophe Marine 1 collaboration
Jinyun Chen 1 collaboration
Gianluca De Rosa 1 collaboration
Aiwen Tan 1 collaboration
Allison Berger 1 collaboration
Gurpanna Saggu 1 collaboration
Eun-Ah Bae 1 collaboration
Linda M Bradley 1 collaboration
Frank Verhaegen 1 collaboration
Karl T Butterworth 1 collaboration
Anthony J Chalmers 1 collaboration
Rob P Coppes 1 collaboration
Dirk de Ruysscher 1 collaboration
Sophie Dobiasch 1 collaboration
John D Fenwick 1 collaboration
Patrick V Granton 1 collaboration
Stefan H J Heijmans 1 collaboration
Mark A Hill 1 collaboration
Kirsten Lauber 1 collaboration
Brian Marples 1 collaboration
Katia Parodi 1 collaboration
Lucas C G G Persoon 1 collaboration
Nick Staut 1 collaboration
Anna Subiel 1 collaboration
Rianne D W Vaes 1 collaboration
Stefan van Hoof 1 collaboration
Ioannis L Verginadis 1 collaboration
Jan J Wilkens 1 collaboration
Kaye J Williams 1 collaboration
George D Wilson 1 collaboration
Ludwig J Dubois 1 collaboration
Fabiana Gregucci 1 collaboration
Sheila Spada 1 collaboration
Mary Helen Barcellos-Hoff 1 collaboration
Nina Bhardwaj 1 collaboration
Charleen Chan Wah Hak 1 collaboration
Alba Fiorentino 1 collaboration
Monica L Guzman 1 collaboration
Kevin Harrington 1 collaboration
Fernanda G Herrera 1 collaboration
Jamie Honeychurch 1 collaboration
Theodore Hong 1 collaboration
Lorea Iturri 1 collaboration
Elisabeth Jaffee 1 collaboration
Sana D Karam 1 collaboration
Simon R V Knott 1 collaboration
David Lyden 1 collaboration
Ariel E Marciscano 1 collaboration
Alan Melcher 1 collaboration
Michele Mondini 1 collaboration
Anna Mondino 1 collaboration
Zachary S Morris 1 collaboration
Sean Pitroda 1 collaboration
Sergio A Quezada 1 collaboration
Laura Santambrogio 1 collaboration
Stephen Shiao 1 collaboration
John Stagg 1 collaboration
Irma Telarovic 1 collaboration
Robert Timmerman 1 collaboration
Marie-Catherine Vozenin 1 collaboration
Ralph Weichselbaum 1 collaboration
James Welsh 1 collaboration
Anna Wilkins 1 collaboration
Chris Xu 1 collaboration
Roberta Zappasodi 1 collaboration
Weiping Zou 1 collaboration
Alexandre Bobard 1 collaboration
Sandra Demaria 1 collaboration
Lorenzo Galluzzi 1 collaboration
Eric Deutsch 1 collaboration
Silvia C Formenti 1 collaboration
Elisavet Krimitza 1 collaboration
George Thyfronitis 1 collaboration
Michael J LaRiviere 1 collaboration
Elise A Chong 1 collaboration
Stephen J Schuster 1 collaboration
John P Plastaras 1 collaboration
Uri Amit 1 collaboration
Ugur Uslu 1 collaboration
Sebastian J Atoche 1 collaboration
Regina M Young 1 collaboration
Carl H June 1 collaboration