Christopher J Podracky

Affiliations

Merkin Institute of Transformative Technologies in Healthcare, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Howard Hughes Medical Institute, Harvard University, Cambridge, MA, USA.
Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA, USA.

Publications (5)

The developing toolkit of continuous directed evolution.

Nature chemical biology

Avec: Mary S Morrison , Christopher J Podracky , David R Liu

Insights into the Autoproteolytic Processing and Catalytic Mechanism of the

Biochemistry

Avec: Brianne M Dudiak , Kenneth R Maksimchuk , Maria M Bednar , Christopher J Podracky , Jonathan M Burg , Tri M Nguyen , Felix O Nwogbo , Raphael H Valdivia , Dewey G McCafferty

Base editing of haematopoietic stem cells rescues sickle cell disease in mice.

Nature

Avec: Gregory A Newby , Jonathan S Yen , Kaitly J Woodard , Thiyagaraj Mayuranathan , Cicera R Lazzarotto , Yichao Li , Heather Sheppard-Tillman , Shaina N Porter , Yu Yao , Kalin Mayberry , Kelcee A Everette , Yoonjeong Jang , Christopher J Podracky , Elizabeth Thaman , Christophe Lechauve , Akshay Sharma , Jordana M Henderson , Michelle F Richter , Kevin T Zhao , Shannon M Miller , Tina Wang , Luke W Koblan , Anton P McCaffrey , John F Tisdale , Theodosia A Kalfa , Shondra M Pruett-Miller , Shengdar Q Tsai , Mitchell J Weiss , David R Liu

Programmable deletion, replacement, integration and inversion of large DNA sequences with twin prime editing.

Nature biotechnology

Avec: Andrew V Anzalone , Xin D Gao , Christopher J Podracky , Andrew T Nelson , Luke W Koblan , Aditya Raguram , Jonathan M Levy , Jaron A M Mercer , David R Liu

Laboratory evolution of a sortase enzyme that modifies amyloid-β protein.

Nature chemical biology

Avec: Christopher J Podracky , Chihui An , Alexandra DeSousa , Brent M Dorr , Dominic M Walsh , David R Liu

Réseau de co-auteurs

David R Liu 4 collaborations

Luke W Koblan 2 collaborations

Mary S Morrison 1 collaboration

Brianne M Dudiak 1 collaboration

Kenneth R Maksimchuk 1 collaboration

Maria M Bednar 1 collaboration

Jonathan M Burg 1 collaboration

Tri M Nguyen 1 collaboration

Felix O Nwogbo 1 collaboration

Raphael H Valdivia 1 collaboration

Dewey G McCafferty 1 collaboration

Gregory A Newby 1 collaboration

Jonathan S Yen 1 collaboration

Kaitly J Woodard 1 collaboration

Thiyagaraj Mayuranathan 1 collaboration

Cicera R Lazzarotto 1 collaboration

Yichao Li 1 collaboration

Heather Sheppard-Tillman 1 collaboration

Shaina N Porter 1 collaboration

Yu Yao 1 collaboration

Kalin Mayberry 1 collaboration

Kelcee A Everette 1 collaboration

Yoonjeong Jang 1 collaboration

Elizabeth Thaman 1 collaboration

Christophe Lechauve 1 collaboration

Akshay Sharma 1 collaboration

Jordana M Henderson 1 collaboration

Michelle F Richter 1 collaboration

Kevin T Zhao 1 collaboration

Shannon M Miller 1 collaboration

Tina Wang 1 collaboration

Anton P McCaffrey 1 collaboration

John F Tisdale 1 collaboration

Theodosia A Kalfa 1 collaboration

Shondra M Pruett-Miller 1 collaboration

Shengdar Q Tsai 1 collaboration

Mitchell J Weiss 1 collaboration

Andrew V Anzalone 1 collaboration

Xin D Gao 1 collaboration

Andrew T Nelson 1 collaboration

Aditya Raguram 1 collaboration

Jonathan M Levy 1 collaboration

Jaron A M Mercer 1 collaboration

Chihui An 1 collaboration

Alexandra DeSousa 1 collaboration

Brent M Dorr 1 collaboration

Dominic M Walsh 1 collaboration