Christian Dienemann

Affiliations
  • Department of Molecular Biology, Max Planck Institute for Biophysical Chemistry, Göttingen, Germany.

Publications (40)

Nucleosome-bound SOX2 and SOX11 structures elucidate pioneer factor function.

Nature
Avec: Svetlana O Dodonova , Fangjie Zhu , Christian Dienemann , Jussi Taipale , Patrick Cramer

Structural basis of TFIIH activation for nucleotide excision repair.

Nature communications
Avec: Goran Kokic , Aleksandar Chernev , Dimitry Tegunov , Christian Dienemann , Henning Urlaub , Patrick Cramer

Mechanism of SARS-CoV-2 polymerase stalling by remdesivir.

Nature communications
Avec: Goran Kokic , Hauke S Hillen , Dimitry Tegunov , Christian Dienemann , Florian Seitz , Jana Schmitzova , Lucas Farnung , Aaron Siewert , Claudia Höbartner , Patrick Cramer

Histone H1 binding to nucleosome arrays depends on linker DNA length and trajectory.

Nature structural & molecular biology
Avec: Marco Dombrowski , Maik Engeholm , Christian Dienemann , Svetlana Dodonova , Patrick Cramer

The 3D structure of lipidic fibrils of α-synuclein.

Nature communications
Avec: Benedikt Frieg , Leif Antonschmidt , Christian Dienemann , James A Geraets , Eszter E Najbauer , Dirk Matthes , Bert L de Groot , Loren B Andreas , Stefan Becker , Christian Griesinger , Gunnar F Schröder

Structural basis of SNAPc-dependent snRNA transcription initiation by RNA polymerase II.

Nature structural & molecular biology
Avec: Srinivasan Rengachari , Sandra Schilbach , Thangavelu Kaliyappan , Jerome Gouge , Kristina Zumer , Juliane Schwarz , Henning Urlaub , Christian Dienemann , Alessandro Vannini , Patrick Cramer

Yeast PIC-Mediator structure with RNA polymerase II C-terminal domain.

Proceedings of the National Academy of Sciences of the United States of America
Avec: Sandra Schilbach , Haibo Wang , Christian Dienemann , Patrick Cramer

Resolution of transcription-induced hexasome-nucleosome complexes by Chd1 and FACT.

Molecular cell
Avec: Maik Engeholm , Johann J Roske , Elisa Oberbeckmann , Christian Dienemann , Michael Lidschreiber , Patrick Cramer , Lucas Farnung

Structure of RNA polymerase II pre-initiation complex at 2.9 Å defines initial DNA opening.

Cell
Avec: Sandra Schilbach , Shintaro Aibara , Christian Dienemann , Frauke Grabbe , Patrick Cramer

Structural basis of RNA processing by human mitochondrial RNase P.

Nature structural & molecular biology
Avec: Arjun Bhatta , Christian Dienemann , Patrick Cramer , Hauke S Hillen

Multi-particle cryo-EM refinement with M visualizes ribosome-antibiotic complex at 3.5 Å in cells.

Nature methods
Avec: Dimitry Tegunov , Liang Xue , Christian Dienemann , Patrick Cramer , Julia Mahamid

Mechanism of molnupiravir-induced SARS-CoV-2 mutagenesis.

Nature structural & molecular biology
Avec: Florian Kabinger , Carina Stiller , Jana Schmitzová , Christian Dienemann , Goran Kokic , Hauke S Hillen , Claudia Höbartner , Patrick Cramer

Neutralization of SARS-CoV-2 by highly potent, hyperthermostable, and mutation-tolerant nanobodies.

The EMBO journal
Avec: Thomas Güttler , Metin Aksu , Antje Dickmanns , Kim M Stegmann , Kathrin Gregor , Renate Rees , Waltraud Taxer , Oleh Rymarenko , Jürgen Schünemann , Christian Dienemann , Philip Gunkel , Bianka Mussil , Jens Krull , Ulrike Teichmann , Uwe Groß , Volker C Cordes , Matthias Dobbelstein , Dirk Görlich

HHT-Related Epistaxis and Pregnancy-A Retrospective Survey and Recommendations for Management from an Otorhinolaryngology Perspective.

Journal of clinical medicine
Avec: Kornelia E C Andorfer , Caroline T Seebauer , Carolin Dienemann , Steven C Marcrum , René Fischer , Christopher Bohr , Thomas S Kühnel

Structure of H3K36-methylated nucleosome-PWWP complex reveals multivalent cross-gyre binding.

Nature structural & molecular biology
Avec: Haibo Wang , Lucas Farnung , Christian Dienemann , Patrick Cramer

Structural Basis of Poxvirus Transcription: Transcribing and Capping Vaccinia Complexes.

Cell
Avec: Hauke S Hillen , Julia Bartuli , Clemens Grimm , Christian Dienemann , Kristina Bedenk , Aladar A Szalay , Utz Fischer , Patrick Cramer

Structure of replicating SARS-CoV-2 polymerase.

Nature
Avec: Hauke S Hillen , Goran Kokic , Lucas Farnung , Christian Dienemann , Dimitry Tegunov , Patrick Cramer

Cryo-EM structure of mammalian RNA polymerase II in complex with human RPAP2.

Communications biology
Avec: Isaac Fianu , Christian Dienemann , Shintaro Aibara , Sandra Schilbach , Patrick Cramer

Structure of an inactive RNA polymerase II dimer.

Nucleic acids research
Avec: Shintaro Aibara , Christian Dienemann , Patrick Cramer

Structural mechanisms of autoinhibition and substrate recognition by the ubiquitin ligase HACE1.

Nature structural & molecular biology
Avec: Jonas Düring , Madita Wolter , Julia J Toplak , Camilo Torres , Olexandr Dybkov , Thornton J Fokkens , Katherine E Bohnsack , Henning Urlaub , Wieland Steinchen , Christian Dienemann , Sonja Lorenz

Quaternary structure of patient-homogenate amplified α-synuclein fibrils modulates seeding of endogenous α-synuclein.

Communications biology
Avec: Benedikt Frieg , James A Geraets , Timo Strohäker , Christian Dienemann , Panagiota Mavroeidi , Byung Chul Jung , Woojin S Kim , Seung-Jae Lee , Maria Xilouri , Markus Zweckstetter , Gunnar F Schröder

Structural insights into human co-transcriptional capping.

Molecular cell
Avec: Gaurika Garg , Christian Dienemann , Lucas Farnung , Juliane Schwarz , Andreas Linden , Henning Urlaub , Patrick Cramer

Structure of the transcription coactivator SAGA.

Nature
Avec: Haibo Wang , Christian Dienemann , Alexandra Stützer , Henning Urlaub , Alan C M Cheung , Patrick Cramer

Structure of SWI/SNF chromatin remodeller RSC bound to a nucleosome.

Nature
Avec: Felix R Wagner , Christian Dienemann , Haibo Wang , Alexandra Stützer , Dimitry Tegunov , Henning Urlaub , Patrick Cramer

Promoter Distortion and Opening in the RNA Polymerase II Cleft.

Molecular cell
Avec: Christian Dienemann , Björn Schwalb , Sandra Schilbach , Patrick Cramer

Structure of the human Mediator-RNA polymerase II pre-initiation complex.

Nature
Avec: Srinivasan Rengachari , Sandra Schilbach , Shintaro Aibara , Christian Dienemann , Patrick Cramer

Structure of the transcribing RNA polymerase II-Elongin complex.

Nature structural & molecular biology
Avec: Ying Chen , Goran Kokic , Christian Dienemann , Olexandr Dybkov , Henning Urlaub , Patrick Cramer

Structural basis of transcription reduction by a promoter-proximal +1 nucleosome.

Molecular cell
Avec: Julio Abril-Garrido , Christian Dienemann , Frauke Grabbe , Taras Velychko , Michael Lidschreiber , Haibo Wang , Patrick Cramer

Regulation of 3' splice site selection after step 1 of splicing by spliceosomal C* proteins.

Science advances
Avec: Olexandr Dybkov , Marco Preußner , Leyla El Ayoubi , Vivi-Yun Feng , Caroline Harnisch , Kilian Merz , Paula Leupold , Peter Yudichev , Dmitry E Agafonov , Cindy L Will , Cyrille Girard , Christian Dienemann , Henning Urlaub , Berthold Kastner , Florian Heyd , Reinhard Lührmann

Impact of distinct FG nucleoporin repeats on Nup98 self-association.

Nature communications
Avec: Alain Ibáñez de Opakua , Christian F Pantoja , Maria-Sol Cima-Omori , Christian Dienemann , Markus Zweckstetter

Structural Basis of Poxvirus Transcription: Vaccinia RNA Polymerase Complexes.

Cell
Avec: Clemens Grimm , Hauke S Hillen , Kristina Bedenk , Julia Bartuli , Simon Neyer , Qian Zhang , Alexander Hüttenhofer , Matthias Erlacher , Christian Dienemann , Andreas Schlosser , Henning Urlaub , Bettina Böttcher , Aladar A Szalay , Patrick Cramer , Utz Fischer

Biospektrum : Zeitschrift der Gesellschaft fur Biologishe Chemie (GBCH) und der Vereinigung fur Allgemeine und Angewandte Mikrobiologie (VAAM)
Avec: Patrick Cramer , Goran Kokic , Christian Dienemann , Claudia Höbartner , Hauke S Hillen

The structure of a dimeric form of SARS-CoV-2 polymerase.

Communications biology
Avec: Florian A Jochheim , Dimitry Tegunov , Hauke S Hillen , Jana Schmitzová , Goran Kokic , Christian Dienemann , Patrick Cramer

Structural basis of Integrator-mediated transcription regulation.

Science (New York, N.Y.)
Avec: Isaac Fianu , Ying Chen , Christian Dienemann , Olexandr Dybkov , Andreas Linden , Henning Urlaub , Patrick Cramer

Allosteric transcription stimulation by RNA polymerase II super elongation complex.

Molecular cell
Avec: Ying Chen , Seychelle M Vos , Christian Dienemann , Momchil Ninov , Henning Urlaub , Patrick Cramer

The clinical drug candidate anle138b binds in a cavity of lipidic α-synuclein fibrils.

Nature communications
Avec: Leif Antonschmidt , Dirk Matthes , Rıza Dervişoğlu , Benedikt Frieg , Christian Dienemann , Andrei Leonov , Evgeny Nimerovsky , Vrinda Sant , Sergey Ryazanov , Armin Giese , Gunnar F Schröder , Stefan Becker , Bert L de Groot , Christian Griesinger , Loren B Andreas

Molecular interactions of FG nucleoporin repeats at high resolution.

Nature chemistry
Avec: Alain Ibáñez de Opakua , James A Geraets , Benedikt Frieg , Christian Dienemann , Adriana Savastano , Marija Rankovic , Maria-Sol Cima-Omori , Gunnar F Schröder , Markus Zweckstetter

Structural basis of catalytic activation in human splicing.

Nature
Avec: Jana Schmitzová , Constantin Cretu , Christian Dienemann , Henning Urlaub , Vladimir Pena

Cryo-EM structures of lipidic fibrils of amyloid-β (1-40).

Nature communications
Avec: Benedikt Frieg , Mookyoung Han , Karin Giller , Christian Dienemann , Dietmar Riedel , Stefan Becker , Loren B Andreas , Christian Griesinger , Gunnar F Schröder

Three-step mechanism of promoter escape by RNA polymerase II.

Molecular cell
Avec: Yumeng Zhan , Frauke Grabbe , Elisa Oberbeckmann , Christian Dienemann , Patrick Cramer

Réseau de co-auteurs

Patrick Cramer 29 collaborations
Henning Urlaub 12 collaborations
Hauke S Hillen 8 collaborations
Goran Kokic 7 collaborations
Dimitry Tegunov 6 collaborations
Sandra Schilbach 6 collaborations
Lucas Farnung 5 collaborations
Benedikt Frieg 5 collaborations
Gunnar F Schröder 5 collaborations
Haibo Wang 5 collaborations
Shintaro Aibara 4 collaborations
Olexandr Dybkov 4 collaborations
Claudia Höbartner 3 collaborations
James A Geraets 3 collaborations
Loren B Andreas 3 collaborations
Stefan Becker 3 collaborations
Christian Griesinger 3 collaborations
Frauke Grabbe 3 collaborations
Jana Schmitzová 3 collaborations
Markus Zweckstetter 3 collaborations
Ying Chen 3 collaborations
Maik Engeholm 2 collaborations
Leif Antonschmidt 2 collaborations
Dirk Matthes 2 collaborations
Bert L de Groot 2 collaborations
Srinivasan Rengachari 2 collaborations
Juliane Schwarz 2 collaborations
Elisa Oberbeckmann 2 collaborations
Michael Lidschreiber 2 collaborations
Julia Bartuli 2 collaborations
Clemens Grimm 2 collaborations
Kristina Bedenk 2 collaborations
Aladar A Szalay 2 collaborations
Utz Fischer 2 collaborations
Isaac Fianu 2 collaborations
Andreas Linden 2 collaborations
Alexandra Stützer 2 collaborations
Alain Ibáñez de Opakua 2 collaborations
Maria-Sol Cima-Omori 2 collaborations
Svetlana O Dodonova 1 collaboration
Fangjie Zhu 1 collaboration
Jussi Taipale 1 collaboration
Aleksandar Chernev 1 collaboration
Florian Seitz 1 collaboration
Jana Schmitzova 1 collaboration
Aaron Siewert 1 collaboration
Marco Dombrowski 1 collaboration
Svetlana Dodonova 1 collaboration
Eszter E Najbauer 1 collaboration
Thangavelu Kaliyappan 1 collaboration
Jerome Gouge 1 collaboration
Kristina Zumer 1 collaboration
Alessandro Vannini 1 collaboration
Johann J Roske 1 collaboration
Arjun Bhatta 1 collaboration
Liang Xue 1 collaboration
Julia Mahamid 1 collaboration
Florian Kabinger 1 collaboration
Carina Stiller 1 collaboration
Thomas Güttler 1 collaboration
Metin Aksu 1 collaboration
Antje Dickmanns 1 collaboration
Kim M Stegmann 1 collaboration
Kathrin Gregor 1 collaboration
Renate Rees 1 collaboration
Waltraud Taxer 1 collaboration
Oleh Rymarenko 1 collaboration
Jürgen Schünemann 1 collaboration
Philip Gunkel 1 collaboration
Bianka Mussil 1 collaboration
Jens Krull 1 collaboration
Ulrike Teichmann 1 collaboration
Uwe Groß 1 collaboration
Volker C Cordes 1 collaboration
Matthias Dobbelstein 1 collaboration
Dirk Görlich 1 collaboration
Kornelia E C Andorfer 1 collaboration
Caroline T Seebauer 1 collaboration
Carolin Dienemann 1 collaboration
Steven C Marcrum 1 collaboration
René Fischer 1 collaboration
Christopher Bohr 1 collaboration
Thomas S Kühnel 1 collaboration
Jonas Düring 1 collaboration
Madita Wolter 1 collaboration
Julia J Toplak 1 collaboration
Camilo Torres 1 collaboration
Thornton J Fokkens 1 collaboration
Katherine E Bohnsack 1 collaboration
Wieland Steinchen 1 collaboration
Sonja Lorenz 1 collaboration
Timo Strohäker 1 collaboration
Panagiota Mavroeidi 1 collaboration
Byung Chul Jung 1 collaboration
Woojin S Kim 1 collaboration
Seung-Jae Lee 1 collaboration
Maria Xilouri 1 collaboration
Gaurika Garg 1 collaboration
Alan C M Cheung 1 collaboration
Felix R Wagner 1 collaboration
Björn Schwalb 1 collaboration
Julio Abril-Garrido 1 collaboration
Taras Velychko 1 collaboration
Marco Preußner 1 collaboration
Leyla El Ayoubi 1 collaboration
Vivi-Yun Feng 1 collaboration
Caroline Harnisch 1 collaboration
Kilian Merz 1 collaboration
Paula Leupold 1 collaboration
Peter Yudichev 1 collaboration
Dmitry E Agafonov 1 collaboration
Cindy L Will 1 collaboration
Cyrille Girard 1 collaboration
Berthold Kastner 1 collaboration
Florian Heyd 1 collaboration
Reinhard Lührmann 1 collaboration
Christian F Pantoja 1 collaboration
Simon Neyer 1 collaboration
Qian Zhang 1 collaboration
Alexander Hüttenhofer 1 collaboration
Matthias Erlacher 1 collaboration
Andreas Schlosser 1 collaboration
Bettina Böttcher 1 collaboration
Florian A Jochheim 1 collaboration
Seychelle M Vos 1 collaboration
Momchil Ninov 1 collaboration
Rıza Dervişoğlu 1 collaboration
Andrei Leonov 1 collaboration
Evgeny Nimerovsky 1 collaboration
Vrinda Sant 1 collaboration
Sergey Ryazanov 1 collaboration
Armin Giese 1 collaboration
Adriana Savastano 1 collaboration
Marija Rankovic 1 collaboration
Constantin Cretu 1 collaboration
Vladimir Pena 1 collaboration
Mookyoung Han 1 collaboration
Karin Giller 1 collaboration
Dietmar Riedel 1 collaboration
Yumeng Zhan 1 collaboration