Chris R Pudney

Affiliations

Department of Biology and Biochemistry, University of Bath, Bath, UK.

Publications (27)

Switching protein metalloporphyrin binding specificity by design from iron to fluorogenic zinc.

Chemical communications (Cambridge, England)

Avec: Benjamin J Bowen , Adam R McGarrity , Jenn-Yeu A Szeto , Christopher R Pudney , D Dafydd Jones

Reliable

Journal of chemical information and modeling

Avec: Rory M Crean , Christopher R Pudney , David K Cole , Marc W van der Kamp

Waxy- or Putty-Like Materials as a Novel Drug Preparation for Synthetic Cannabinoid Receptor Agonists: Detection in Prisons and In Vitro Cannabinoid Receptor Activity.

Drug testing and analysis

Avec: Axelle Timmerman , Marie H Deventer , Rachael Andrews , Robert Reid , Victoria Marland , Darren Edwards , Christopher R Pudney , Niamh Nic Daéid , Christophe P Stove , Caitlyn Norman

Excitation-Energy-Dependent Molecular Beacon Detects Early Stage Neurotoxic Aβ Aggregates in the Presence of Cortical Neurons.

ACS chemical neuroscience

Avec: Christina E Gulácsy , Richard Meade , Dragana A M Catici , Christian Soeller , G Dan Pantos , D Dafydd Jones , Dominic Alibhai , Mark Jepson , Ventsislav K Valev , Jody M Mason , Robert J Williams , Christopher R Pudney

A Thermodynamic Model for Interpreting Tryptophan Excitation-Energy-Dependent Fluorescence Spectra Provides Insight Into Protein Conformational Sampling and Stability.

Frontiers in molecular biosciences

Avec: A Kwok , I S Camacho , S Winter , M Knight , R M Meade , M W Van der Kamp , A Turner , J O'Hara , J M Mason , A R Jones , V L Arcus , C R Pudney

Structure and

Open biology

Avec: Nehad Noby , Husam Sabah Auhim , Samuel Winter , Harley L Worthy , Amira M Embaby , Hesham Saeed , Ahmed Hussein , Christopher R Pudney , Pierre J Rizkallah , Stephen A Wells , D Dafydd Jones

Glycosylation increases active site rigidity leading to improved enzyme stability and turnover.

The FEBS journal

Avec: Krithika Ramakrishnan , Rachel L Johnson , Samuel D Winter , Harley L Worthy , Christopher Thomas , Diana C Humer , Oliver Spadiut , Sarah H Hindson , Stephen Wells , Andrew H Barratt , Georgina E Menzies , Christopher R Pudney , D Dafydd Jones

Instant Detection of Synthetic Cannabinoids on Physical Matrices, Implemented on a Low-Cost, Ultraportable Device.

Analytical chemistry

Avec: Gyles E Cozier , Rachael C Andrews , Anca Frinculescu , Ranjeet Kumar , Benedict May , Tom Tooth , Peter Collins , Andrew Costello , Tom S F Haines , Tom P Freeman , Ian S Blagbrough , Jennifer Scott , Trevor Shine , Oliver B Sutcliffe , Stephen M Husbands , Jonathan Leach , Richard W Bowman , Christopher R Pudney

Detection and quantification of synthetic cannabinoids in seven illicitly sourced disposable vapes submitted by an individual presenting to a UK drug and alcohol service.

Addiction (Abingdon, England)

Avec: Sam Craft , Peter Sunderland , Molly F Millea , Christopher R Pudney , Oliver B Sutcliffe , Tom P Freeman

Synthetic Cannabinoid Receptor Agonists Detection Using Fluorescence Spectral Fingerprinting.

Analytical chemistry

Avec: Benedict May , Husain A Naqi , Michael Tipping , Jenny Scott , Stephen M Husbands , Ian S Blagbrough , Christopher R Pudney

Conformation control of the histidine kinase BceS of Bacillus subtilis by its cognate ABC-transporter facilitates need-based activation of antibiotic resistance.

Molecular microbiology

Avec: Alan Koh , Marjorie J Gibbon , Marc W Van der Kamp , Christopher R Pudney , Susanne Gebhard

Cooperative Conformational Transitions Underpin the Activation Heat Capacity in the Temperature Dependence of Enzyme Catalysis.

ACS catalysis

Avec: Emma J Walker , Carlin J Hamill , Rory Crean , Michael S Connolly , Annmaree K Warrender , Kirsty L Kraakman , Erica J Prentice , Alistair Steyn-Ross , Moira Steyn-Ross , Christopher R Pudney , Marc W van der Kamp , Louis A Schipper , Adrian J Mulholland , Vickery L Arcus

Exposing the Interplay Between Enzyme Turnover, Protein Dynamics, and the Membrane Environment in Monoamine Oxidase B.

Biochemistry

Avec: Hannah B L Jones , Rory M Crean , Anna Mullen , Emanuele G Kendrick , Steven D Bull , Stephen A Wells , David R Carbery , Fraser MacMillan , Marc W van der Kamp , Christopher R Pudney

Enzyme evolution and the temperature dependence of enzyme catalysis.

Current opinion in structural biology

Avec: Vickery L Arcus , Marc W van der Kamp , Christopher R Pudney , Adrian J Mulholland

Sensing Enzyme Activation Heat Capacity at the Single-Molecule Level Using Gold-Nanorod-Based Optical Whispering Gallery Modes.

ACS applied nano materials

Avec: Sivaraman Subramanian , Hannah B L Jones , Simona Frustaci , Samuel Winter , Marc W van der Kamp , Vickery L Arcus , Christopher R Pudney , Frank Vollmer

Rigidifying a

ACS catalysis

Avec: Sarah A Hindson , H Adrian Bunzel , Bettina Frank , Dimitri A Svistunenko , Christopher Williams , Marc W van der Kamp , Adrian J Mulholland , Christopher R Pudney , J L Ross Anderson

Synthetic cannabinoid receptor agonists are monoamine oxidase-A selective inhibitors.

The FEBS journal

Avec: Sarah A Hindson , Rachael C Andrews , Michael J Danson , Marc W van der Kamp , Amy E Manley , Oliver B Sutcliffe , Tom S F Haines , Tom P Freeman , Jennifer Scott , Stephen M Husbands , Ian S Blagbrough , J L Ross Anderson , David R Carbery , Christopher R Pudney

Constant domain polymorphisms influence monoclonal antibody stability and dynamics.

Protein science : a publication of the Protein Society

Avec: Annmaree K Warrender , Jolyn Pan , Chris R Pudney , Vickery L Arcus , William Kelton

Specificity of bispecific T cell receptors and antibodies targeting peptide-HLA.

The Journal of clinical investigation

Avec: Christopher J Holland , Rory M Crean , Johanne M Pentier , Ben de Wet , Angharad Lloyd , Velupillai Srikannathasan , Nikolai Lissin , Katy A Lloyd , Thomas H Blicher , Paul J Conroy , Miriam Hock , Robert J Pengelly , Thomas E Spinner , Brian Cameron , Elizabeth A Potter , Anitha Jeyanthan , Peter E Molloy , Malkit Sami , Milos Aleksic , Nathaniel Liddy , Ross A Robinson , Stephen Harper , Marco Lepore , Chris R Pudney , Marc W van der Kamp , Pierre J Rizkallah , Bent K Jakobsen , Annelise Vuidepot , David K Cole

Monoclonal antibody stability can be usefully monitored using the excitation-energy-dependent fluorescence edge-shift.

The Biochemical journal

Avec: Michael J Knight , Rachel E Woolley , Anthony Kwok , Stuart Parsons , Hannah B L Jones , Christina E Gulácsy , Polly Phaal , Omar Kassaar , Kieran Dawkins , Elizabeth Rodriguez , Andreia Marques , Leo Bowsher , Stephen A Wells , Andrew Watts , Jean M H van den Elsen , Alison Turner , John O'Hara , Christopher R Pudney

Peptide cargo tunes a network of correlated motions in human leucocyte antigens.

The FEBS journal

Avec: Jade R Hopkins , Rory M Crean , Dragana A M Catici , Andrew K Sewell , Vickery L Arcus , Marc W Van der Kamp , David K Cole , Christopher R Pudney

Chemical Mapping Exposes the Importance of Active Site Interactions in Governing the Temperature Dependence of Enzyme Turnover.

ACS catalysis

Avec: Samuel D Winter , Hannah B L Jones , Dora M Răsădean , Rory M Crean , Michael J Danson , G Dan Pantoş , Gergely Katona , Erica Prentice , Vickery L Arcus , Marc W van der Kamp , Christopher R Pudney

Molecular Rules Underpinning Enhanced Affinity Binding of Human T Cell Receptors Engineered for Immunotherapy.

Molecular therapy oncolytics

Avec: Rory M Crean , Bruce J MacLachlan , Florian Madura , Thomas Whalley , Pierre J Rizkallah , Christopher J Holland , Catriona McMurran , Stephen Harper , Andrew Godkin , Andrew K Sewell , Christopher R Pudney , Marc W van der Kamp , David K Cole

Trends in hospital presentations following analytically confirmed synthetic cannabinoid receptor agonist exposure before and after implementation of the 2016 UK Psychoactive Substances Act.

Addiction (Abingdon, England)

Avec: Sam Craft , Michael Dunn , Dan Vidler , Jane Officer , Ian S Blagbrough , Christopher R Pudney , Graeme Henderson , Ahmed Abouzeid , Paul I Dargan , Michael Eddleston , Jamie Cooper , Simon L Hill , Clair Roper , Tom P Freeman , Simon H L Thomas

Synthetic cannabinoid use in an adult male prison in the UK.

The International journal on drug policy

Avec: Sam Craft , Alice Austin , Tom Tooth , Catherine Glover , Tina Garrett , Ian S Blagbrough , Peter Sunderland , Christopher R Pudney , Tom P Freeman

Photochemical Fingerprinting Is a Sensitive Probe for the Detection of Synthetic Cannabinoid Receptor Agonists; toward Robust Point-of-Care Detection.

Analytical chemistry

Avec: Rachael C Andrews , Benedict May , Federico J Hernández , Gyles E Cozier , Piers A Townsend , Oliver B Sutcliffe , Tom S F Haines , Tom P Freeman , Jennifer Scott , Stephen M Husbands , Ian S Blagbrough , Richard W Bowman , Simon E Lewis , Matthew N Grayson , Rachel Crespo-Otero , David R Carbery , Christopher R Pudney

Delineation of the complete reaction cycle of a natural Diels-Alderase.

Chemical science

Avec: Laurence Maschio , Catherine R Back , Jawaher Alnawah , James I Bowen , Samuel T Johns , Sbusisiwe Z Mbatha , Li-Chen Han , Nicholas R Lees , Katja Zorn , James E M Stach , Martin A Hayes , Marc W van der Kamp , Christopher R Pudney , Steven G Burston , Christine L Willis , Paul R Race

Réseau de co-auteurs

Christopher R Pudney 24 collaborations

Marc W van der Kamp 11 collaborations

Rory M Crean 6 collaborations

Tom P Freeman 6 collaborations

Ian S Blagbrough 6 collaborations

Vickery L Arcus 6 collaborations

D Dafydd Jones 4 collaborations

David K Cole 4 collaborations

Oliver B Sutcliffe 4 collaborations

Stephen M Husbands 4 collaborations

Hannah B L Jones 4 collaborations

Pierre J Rizkallah 3 collaborations

Stephen A Wells 3 collaborations

Rachael C Andrews 3 collaborations

Benedict May 3 collaborations

Tom S F Haines 3 collaborations

Jennifer Scott 3 collaborations

Sam Craft 3 collaborations

Adrian J Mulholland 3 collaborations

David R Carbery 3 collaborations

Christina E Gulácsy 2 collaborations

Dragana A M Catici 2 collaborations

Samuel Winter 2 collaborations

Harley L Worthy 2 collaborations

Samuel D Winter 2 collaborations

Gyles E Cozier 2 collaborations

Tom Tooth 2 collaborations

Richard W Bowman 2 collaborations

Peter Sunderland 2 collaborations

Marc W Van der Kamp 2 collaborations

Annmaree K Warrender 2 collaborations

Sarah A Hindson 2 collaborations

J L Ross Anderson 2 collaborations

Michael J Danson 2 collaborations

Christopher J Holland 2 collaborations

Stephen Harper 2 collaborations

Andrew K Sewell 2 collaborations

Benjamin J Bowen 1 collaboration

Adam R McGarrity 1 collaboration

Jenn-Yeu A Szeto 1 collaboration

Axelle Timmerman 1 collaboration

Marie H Deventer 1 collaboration

Rachael Andrews 1 collaboration

Robert Reid 1 collaboration

Victoria Marland 1 collaboration

Darren Edwards 1 collaboration

Niamh Nic Daéid 1 collaboration

Christophe P Stove 1 collaboration

Caitlyn Norman 1 collaboration

Richard Meade 1 collaboration

Christian Soeller 1 collaboration

G Dan Pantos 1 collaboration

Dominic Alibhai 1 collaboration

Mark Jepson 1 collaboration

Ventsislav K Valev 1 collaboration

Jody M Mason 1 collaboration

Robert J Williams 1 collaboration

A Kwok 1 collaboration

I S Camacho 1 collaboration

S Winter 1 collaboration

M Knight 1 collaboration

R M Meade 1 collaboration

M W Van der Kamp 1 collaboration

A Turner 1 collaboration

J O'Hara 1 collaboration

J M Mason 1 collaboration

A R Jones 1 collaboration

V L Arcus 1 collaboration

C R Pudney 1 collaboration

Nehad Noby 1 collaboration

Husam Sabah Auhim 1 collaboration

Amira M Embaby 1 collaboration

Hesham Saeed 1 collaboration

Ahmed Hussein 1 collaboration

Krithika Ramakrishnan 1 collaboration

Rachel L Johnson 1 collaboration

Christopher Thomas 1 collaboration

Diana C Humer 1 collaboration

Oliver Spadiut 1 collaboration

Sarah H Hindson 1 collaboration

Stephen Wells 1 collaboration

Andrew H Barratt 1 collaboration

Georgina E Menzies 1 collaboration

Anca Frinculescu 1 collaboration

Ranjeet Kumar 1 collaboration

Peter Collins 1 collaboration

Andrew Costello 1 collaboration

Trevor Shine 1 collaboration

Jonathan Leach 1 collaboration

Molly F Millea 1 collaboration

Husain A Naqi 1 collaboration

Michael Tipping 1 collaboration

Jenny Scott 1 collaboration

Alan Koh 1 collaboration

Marjorie J Gibbon 1 collaboration

Susanne Gebhard 1 collaboration

Emma J Walker 1 collaboration

Carlin J Hamill 1 collaboration

Rory Crean 1 collaboration

Michael S Connolly 1 collaboration

Kirsty L Kraakman 1 collaboration

Erica J Prentice 1 collaboration

Alistair Steyn-Ross 1 collaboration

Moira Steyn-Ross 1 collaboration

Louis A Schipper 1 collaboration

Anna Mullen 1 collaboration

Emanuele G Kendrick 1 collaboration

Steven D Bull 1 collaboration

Fraser MacMillan 1 collaboration

Sivaraman Subramanian 1 collaboration

Simona Frustaci 1 collaboration

Frank Vollmer 1 collaboration

H Adrian Bunzel 1 collaboration

Bettina Frank 1 collaboration

Dimitri A Svistunenko 1 collaboration

Christopher Williams 1 collaboration

Amy E Manley 1 collaboration

Jolyn Pan 1 collaboration

William Kelton 1 collaboration

Johanne M Pentier 1 collaboration

Ben de Wet 1 collaboration

Angharad Lloyd 1 collaboration

Velupillai Srikannathasan 1 collaboration

Nikolai Lissin 1 collaboration

Katy A Lloyd 1 collaboration

Thomas H Blicher 1 collaboration

Paul J Conroy 1 collaboration

Miriam Hock 1 collaboration

Robert J Pengelly 1 collaboration

Thomas E Spinner 1 collaboration

Brian Cameron 1 collaboration

Elizabeth A Potter 1 collaboration

Anitha Jeyanthan 1 collaboration

Peter E Molloy 1 collaboration

Malkit Sami 1 collaboration

Milos Aleksic 1 collaboration

Nathaniel Liddy 1 collaboration

Ross A Robinson 1 collaboration

Marco Lepore 1 collaboration

Bent K Jakobsen 1 collaboration

Annelise Vuidepot 1 collaboration

Michael J Knight 1 collaboration

Rachel E Woolley 1 collaboration

Anthony Kwok 1 collaboration

Stuart Parsons 1 collaboration

Polly Phaal 1 collaboration

Omar Kassaar 1 collaboration

Kieran Dawkins 1 collaboration

Elizabeth Rodriguez 1 collaboration

Andreia Marques 1 collaboration

Leo Bowsher 1 collaboration

Andrew Watts 1 collaboration

Jean M H van den Elsen 1 collaboration

Alison Turner 1 collaboration

John O'Hara 1 collaboration

Jade R Hopkins 1 collaboration

Dora M Răsădean 1 collaboration

G Dan Pantoş 1 collaboration

Gergely Katona 1 collaboration

Erica Prentice 1 collaboration

Bruce J MacLachlan 1 collaboration

Florian Madura 1 collaboration

Thomas Whalley 1 collaboration

Catriona McMurran 1 collaboration

Andrew Godkin 1 collaboration

Michael Dunn 1 collaboration

Dan Vidler 1 collaboration

Jane Officer 1 collaboration

Graeme Henderson 1 collaboration

Ahmed Abouzeid 1 collaboration

Paul I Dargan 1 collaboration

Michael Eddleston 1 collaboration

Jamie Cooper 1 collaboration

Simon L Hill 1 collaboration

Clair Roper 1 collaboration

Simon H L Thomas 1 collaboration

Alice Austin 1 collaboration

Catherine Glover 1 collaboration

Tina Garrett 1 collaboration

Federico J Hernández 1 collaboration

Piers A Townsend 1 collaboration

Simon E Lewis 1 collaboration

Matthew N Grayson 1 collaboration

Rachel Crespo-Otero 1 collaboration

Laurence Maschio 1 collaboration

Catherine R Back 1 collaboration

Jawaher Alnawah 1 collaboration

James I Bowen 1 collaboration

Samuel T Johns 1 collaboration

Sbusisiwe Z Mbatha 1 collaboration

Li-Chen Han 1 collaboration

Nicholas R Lees 1 collaboration

Katja Zorn 1 collaboration

James E M Stach 1 collaboration

Martin A Hayes 1 collaboration

Steven G Burston 1 collaboration

Christine L Willis 1 collaboration

Paul R Race 1 collaboration