Carolin Helten

Affiliations

Division of Cardiology, Pulmonology, and Vascular Medicine, Heinrich Heine University Medical Center Düsseldorf, Düsseldorf, Germany.

Publications (28)

A novel mechanism of ACE inhibition-associated enhanced platelet reactivity: disproof of the ARB-MI paradox?

European journal of clinical pharmacology

Avec: Carolin Helten , Philipp Mourikis , Lisa Dannenberg , René M'Pembele , Kajetan Trojovsky , Aysel Ayhan , Christina Kohlmorgen , Maria Grandoch , Bodo Levkau , Verena Veulemans , Tobias Petzold , Thomas Hohlfeld , Malte Kelm , Tobias Zeus , Amin Polzin

Platelet Reactivity in Patients on Aspirin and Clopidogrel Therapy Measured by a New Bedside Whole-Blood Assay.

Journal of cardiovascular pharmacology

Avec: Amin Polzin , Carolin Helten , Lisa Dannenberg , Philipp Mourikis , David Naguib , Alina Achilles , Betül Knoop , Saif Zako , Susanne Rehder , Klaus Görlinger , Bodo Levkau , Tobias Zeus , Malte Kelm , Thomas Hohlfeld , Till Hoffmann

Enhanced Platelet Reactivity under Aspirin Medication and Major Adverse Cardiac and Cerebrovascular Events in Patients with Coronary Artery Disease.

Pharmacology

Avec: Lisa Dannenberg , Daniel Metzen , Saif Zako , Martin Pöhl , Philipp Mourikis , Carolin Helten , Kajetan Trojovsky , David Naguib , Daniel Konsek , Betül Knoop , Aysel Ayhan , Thomas Hohlfeld , Tobias Petzold , Bodo Levkau , Verena Veulemans , Tobias Zeus , Malte Kelm , Amin Polzin

Dose reduction, oral application, and order of intake to preserve aspirin antiplatelet effects in dipyrone co-medicated chronic artery disease patients.

European journal of clinical pharmacology

Avec: Lisa Dannenberg , Tobias Petzold , Alina Achilles , David Naguib , Saif Zako , Carolin Helten , René M'Pembele , Philipp Mourikis , Yanina Podsvyadek , Maria Grandoch , Bodo Levkau , Tobias Zeus , Malte Kelm , Thomas Hohlfeld , Amin Polzin

Sphingosine-1-phosphate: A mediator of the ARB-MI paradox?

International journal of cardiology

Avec: Amin Polzin , Carolin Helten , Lisa Dannenberg , Tina Müller , Markus Gräler , Malte Kelm , Bodo Levkau

Platelet reactivity is higher in e-cigarette vaping as compared to traditional smoking.

International journal of cardiology

Avec: Daniel Metzen , René M'Pembele , Saif Zako , Philipp Mourikis , Carolin Helten , Dorothee Zikeli , Samantha Ahlbrecht , Denis Ignatov , Aysel Ayhan , Ragnar Huhn , Tobias Zeus , Bodo Levkau , Tobias Petzold , Malte Kelm , Lisa Dannenberg , Amin Polzin

TAVR: nemesis of NOACs?

Journal of thrombosis and thrombolysis

Avec: Amin Polzin , Carolin Helten , Daniel Metzen , Saif Zako , Verena Veulemans , Malte Kelm , Tobias Zeus

Rivaroxaban Reduces Arterial Thrombosis by Inhibition of FXa-Driven Platelet Activation via Protease Activated Receptor-1.

Circulation research

Avec: Tobias Petzold , Manuela Thienel , Lisa Dannenberg , Philipp Mourikis , Carolin Helten , Aysel Ayhan , René M'Pembele , Alina Achilles , Kajetan Trojovky , Daniel Konsek , Zhe Zhang , Ron Regenauer , Joachim Pircher , Andreas Ehrlich , Enzo Lüsebrink , Leo Nicolai , Thomas J Stocker , Richard Brandl , Franz Röschenthaler , Jan Strecker , Inas Saleh , Michael Spannagl , Christoph H Mayr , Herbert B Schiller , Christian Jung , Norbert Gerdes , Till Hoffmann , Bodo Levkau , Thomas Hohlfeld , Tobias Zeus , Christian Schulz , Malte Kelm , Amin Polzin

Excess Mortality in Aspirin and Dipyrone (Metamizole) Co-Medicated in Patients With Cardiovascular Disease: A Nationwide Study.

Journal of the American Heart Association

Avec: Amin Polzin , Lisa Dannenberg , Carolin Helten , Martin Pöhl , Daniel Metzen , Philipp Mourikis , Christof Dücker , Ursula Marschall , Helmut L'Hoest , Beata Hennig , Saif Zako , Kajetan Trojovsky , Tobias Petzold , Christian Jung , Bodo Levkau , Tobias Zeus , Karsten Schrör , Thomas Hohlfeld , Malte Kelm

MTX Treatment Does Not Improve Outcome in Mice with AMI.

Pharmacology

Avec: Lisa Dannenberg , Kajetan Trojovsky , Aysel Ayhan , Carolin Helten , Saif Zako , René M'Pembele , Philipp Mourikis , Marcel Benkhoff , Denis Ignatov , Theresia Sarabhai , Tobias Petzold , Ragnar Huhn-Wientgen , Tobias Zeus , Malte Kelm , Bodo Levkau , Amin Polzin

High On-Treatment Platelet Reactivity: Aspirin versus Clopidogrel.

Pharmacology

Avec: René M'Pembele , Samantha Ahlbrecht , Carolin Helten , Philipp Mourikis , David Naguib , Saif Zako , Kajetan Trojovsky , Ragnar Huhn , Tobias Petzold , Thomas Hohlfeld , Tobias Zeus , Malte Kelm , Lisa Dannenberg , Amin Polzin

Revealing concealed cardioprotection by platelet Mfsd2b-released S1P in human and murine myocardial infarction.

Nature communications

Avec: Amin Polzin , Lisa Dannenberg , Marcel Benkhoff , Maike Barcik , Carolin Helten , Philipp Mourikis , Samantha Ahlbrecht , Laura Wildeis , Justus Ziese , Dorothee Zikeli , Daniel Metzen , Hao Hu , Leonard Baensch , Nathalie H Schröder , Petra Keul , Sarah Weske , Philipp Wollnitzke , Dragos Duse , Süreyya Saffak , Mareike Cramer , Florian Bönner , Tina Müller , Markus H Gräler , Tobias Zeus , Malte Kelm , Bodo Levkau

Risk prediction of bleeding and MACCE by PRECISE-DAPT score post-PCI.

International journal of cardiology. Heart & vasculature

Avec: Lisa Dannenberg , Shazia Afzal , Natalia Czychy , René M'Pembele , Saif Zako , Carolin Helten , Philipp Mourikis , Dorothee Zikeli , Samantha Ahlbrecht , Kajetan Trojovsky , Marcel Benkhoff , Maike Barcik , Georg Wolff , Tobias Zeus , Malte Kelm , Amin Polzin

Aspirin I.V. Loading during Elective Percutaneous Coronary Intervention.

Pharmacology

Avec: David Naguib , Carolin Helten , Saif Zako , Philipp Mourikis , René M'Pembele , Kajetan Trojovsky , Samantha Ahlbrecht , Dorothee Zikeli , Tobias Zeus , Malte Kelm , Lisa Dannenberg , Amin Polzin

Sphingosine-1-phosphate improves outcome of no-reflow acute myocardial infarction via sphingosine-1-phosphate receptor 1.

ESC heart failure

Avec: Amin Polzin , Lisa Dannenberg , Marcel Benkhoff , Maike Barcik , Petra Keul , Aysel Ayhan , Sarah Weske , Samantha Ahlbrecht , Kajetan Trojovsky , Carolin Helten , Sebastian Haberkorn , Ulrich Flögel , Tobias Zeus , Tina Müller , Markus H Gräler , Malte Kelm , Bodo Levkau

Targeting Sphingosine-1-Phosphate Signaling to Prevent the Progression of Aortic Valve Disease.

Circulation

Avec: Marcel Benkhoff , Maike Barcik , Philipp Mourikis , Jana Dahlmanns , Paulina Kahmann , Philipp Wollnitzke , Moritz Hering , Tim Huckenbeck , Julia Hoppe , Nina Semleit , Jennifer Deister-Jonas , Saif Zako , Jasmin Seel , Cristina Coman , Mareike Barth , Mareike Cramer , Carolin Helten , Laura Wildeis , Hao Hu , Gabrielle Al-Kassis , Daniel Metzen , Julia Hesse , Jessica Weber , Lisa Dannenberg , Payam Akhyari , Artur Lichtenberg , Christine Quast , Norbert Gerdes , Tobias Zeus , Oliver Borst , Malte Kelm , Tobias Petzold , Robert Ahrends , Bodo Levkau , Amin Polzin

Antiplatelet effects of aspirin and clopidogrel after left atrial appendage (LAA) occluder implantation.

International journal of cardiology

Avec: Lisa Dannenberg , Philipp Mourikis , David Naguib , Saif Zako , Carolin Helten , René M'Pembele , Kajetan Trojovsky , Daniel Konsek , Georg Wolff , Maximilian Brockmeyer , Volker Schulze , Bodo Levkau , Thomas Hohlfeld , Tobias Zeus , Malte Kelm , Amin Polzin

Aspirin antiplatelet effects are associated with body weight.

Vascular pharmacology

Avec: Philipp Mourikis , Saif Zako , Lisa Dannenberg , Carolin Helten , David Naguib , Thomas Hohlfeld , Tobias Petzold , Bodo Levkau , Tobias Zeus , Malte Kelm , Amin Polzin

Impact of Transcatheter Aortic Valve Implantation on Thrombin Generation and Platelet Function.

Thrombosis and haemostasis

Avec: Philipp Mourikis , Lisa Dannenberg , Saif Zako , Carolin Helten , René M'Pembele , Hannah Richter , Thomas Hohlfeld , Christian Jung , Tobias Zeus , Malte Kelm , Verena Veulemans , Amin Polzin

Rivaroxaban attenuates neutrophil maturation in the bone marrow niche.

Basic research in cardiology

Avec: R Schneckmann , M Döring , S Gerfer , S Gorressen , S Heitmeier , C Helten , A Polzin , C Jung , M Kelm , A C Fender , U Flögel , M Grandoch

Malondialdehyde Assay in the Evaluation of Aspirin Antiplatelet Effects.

Pharmacology

Avec: Amin Polzin , Lisa Dannenberg , Theresa Schneider , Betül Knoop , David Naguib , Carolin Helten , Martin Pöhl , Malte Kelm , Tobias Zeus , Thomas Hohlfeld

Platelet reactivity in patients with chronic kidney disease and hemodialysis.

Journal of thrombosis and thrombolysis

Avec: Philipp Mourikis , Carolin Helten , Lisa Dannenberg , Thomas Hohlfeld , Johannes Stegbauer , Tobias Petzold , Bodo Levkau , Tobias Zeus , Malte Kelm , Amin Polzin

Cardioprotection by very mild hypothermia in mice.

Cardiovascular diagnosis and therapy

Avec: Betül Knoop , David Naguib , Lisa Dannenberg , Carolin Helten , Saif Zako , Christian Jung , Bodo Levkau , Maria Grandoch , Malte Kelm , Tobias Zeus , Amin Polzin

Non-vitamin K oral anticoagulants (NOAC) and the risk of myocardial infarction: Differences between factor IIa and factor Xa inhibition?

Pharmacology & therapeutics

Avec: Amin Polzin , Lisa Dannenberg , Georg Wolff , Carolin Helten , Alina Achilles , Thomas Hohlfeld , Tobias Zeus , Malte Kelm , Steffen Massberg , Tobias Petzold

Safety and efficacy of Tirofiban in STEMI-patients.

International journal of cardiology

Avec: Lisa Dannenberg , Georg Wolff , David Naguib , Martin Pöhl , Saif Zako , Carolin Helten , Philipp Mourikis , Bodo Levkau , Thomas Hohlfeld , Tobias Zeus , Malte Kelm , Volker Schulze , Amin Polzin

Dapagliflozin reduces thrombin generation and platelet activation: implications for cardiovascular risk reduction in type 2 diabetes mellitus.

Diabetologia

Avec: Christina Kohlmorgen , Stephen Gerfer , Kathrin Feldmann , Sören Twarock , Sonja Hartwig , Stefan Lehr , Meike Klier , Irena Krüger , Carolin Helten , Petra Keul , Sabine Kahl , Amin Polzin , Margitta Elvers , Ulrich Flögel , Malte Kelm , Bodo Levkau , Michael Roden , Jens W Fischer , Maria Grandoch

Staphylococcus aureus increases platelet reactivity in patients with infective endocarditis.

Scientific reports

Avec: Amin Polzin , Lisa Dannenberg , René M'Pembele , Philipp Mourikis , David Naguib , Saif Zako , Carolin Helten , Tobias Petzold , Bodo Levkau , Thomas Hohlfeld , Mareike Barth , Tobias Zeus , Stephan Sixt , Ragnar Huhn , Payam Akhyari , Artur Lichtenberg , Malte Kelm , Till Hoffmann

Heparin dosing in patients with Impella-supported cardiogenic shock.

International journal of cardiology

Avec: Christophe Vandenbriele , René M'Pembele , Lisa Dannenberg , Daniel Metzen , Saif Zako , Carolin Helten , Philipp Mourikis , Denis Ignatov , Ragnar Huhn , Tim Balthazar , Tom Adriaenssens , Thomas Vanassche , Bart Meyns , Vasileios Panoulas , Maria Monteagudo-Vela , Deepa Arachchillage , Stefan Janssens , Clemens Scherer , Martin Orban , Tobias Petzold , Patrick Horn , Christian Jung , Tobias Zeus , Susanna Price , Ralf Westenfeld , Malte Kelm , Amin Polzin

Réseau de co-auteurs

Malte Kelm 27 collaborations

Amin Polzin 27 collaborations

Lisa Dannenberg 25 collaborations

Tobias Zeus 25 collaborations

Philipp Mourikis 20 collaborations

Bodo Levkau 19 collaborations

Saif Zako 18 collaborations

Thomas Hohlfeld 15 collaborations

Tobias Petzold 14 collaborations

René M'Pembele 12 collaborations

David Naguib 11 collaborations

Kajetan Trojovsky 9 collaborations

Daniel Metzen 7 collaborations

Aysel Ayhan 6 collaborations

Samantha Ahlbrecht 6 collaborations

Christian Jung 5 collaborations

Marcel Benkhoff 5 collaborations

Maria Grandoch 4 collaborations

Verena Veulemans 4 collaborations

Alina Achilles 4 collaborations

Betül Knoop 4 collaborations

Martin Pöhl 4 collaborations

Dorothee Zikeli 4 collaborations

Ragnar Huhn 4 collaborations

Maike Barcik 4 collaborations

Georg Wolff 4 collaborations

Till Hoffmann 3 collaborations

Daniel Konsek 3 collaborations

Tina Müller 3 collaborations

Denis Ignatov 3 collaborations

Petra Keul 3 collaborations

Christina Kohlmorgen 2 collaborations

Norbert Gerdes 2 collaborations

Laura Wildeis 2 collaborations

Hao Hu 2 collaborations

Sarah Weske 2 collaborations

Philipp Wollnitzke 2 collaborations

Mareike Cramer 2 collaborations

Markus H Gräler 2 collaborations

Ulrich Flögel 2 collaborations

Mareike Barth 2 collaborations

Payam Akhyari 2 collaborations

Artur Lichtenberg 2 collaborations

Volker Schulze 2 collaborations

Susanne Rehder 1 collaboration

Klaus Görlinger 1 collaboration

Yanina Podsvyadek 1 collaboration

Markus Gräler 1 collaboration

Manuela Thienel 1 collaboration

Kajetan Trojovky 1 collaboration

Zhe Zhang 1 collaboration

Ron Regenauer 1 collaboration

Joachim Pircher 1 collaboration

Andreas Ehrlich 1 collaboration

Enzo Lüsebrink 1 collaboration

Leo Nicolai 1 collaboration

Thomas J Stocker 1 collaboration

Richard Brandl 1 collaboration

Franz Röschenthaler 1 collaboration

Jan Strecker 1 collaboration

Inas Saleh 1 collaboration

Michael Spannagl 1 collaboration

Christoph H Mayr 1 collaboration

Herbert B Schiller 1 collaboration

Christian Schulz 1 collaboration

Christof Dücker 1 collaboration

Ursula Marschall 1 collaboration

Helmut L'Hoest 1 collaboration

Beata Hennig 1 collaboration

Karsten Schrör 1 collaboration

Theresia Sarabhai 1 collaboration

Ragnar Huhn-Wientgen 1 collaboration

Justus Ziese 1 collaboration

Leonard Baensch 1 collaboration

Nathalie H Schröder 1 collaboration

Dragos Duse 1 collaboration

Süreyya Saffak 1 collaboration

Florian Bönner 1 collaboration

Shazia Afzal 1 collaboration

Natalia Czychy 1 collaboration

Sebastian Haberkorn 1 collaboration

Jana Dahlmanns 1 collaboration

Paulina Kahmann 1 collaboration

Moritz Hering 1 collaboration

Tim Huckenbeck 1 collaboration

Julia Hoppe 1 collaboration

Nina Semleit 1 collaboration

Jennifer Deister-Jonas 1 collaboration

Jasmin Seel 1 collaboration

Cristina Coman 1 collaboration

Gabrielle Al-Kassis 1 collaboration

Julia Hesse 1 collaboration

Jessica Weber 1 collaboration

Christine Quast 1 collaboration

Oliver Borst 1 collaboration

Robert Ahrends 1 collaboration

Maximilian Brockmeyer 1 collaboration

Hannah Richter 1 collaboration

R Schneckmann 1 collaboration

M Döring 1 collaboration

S Gerfer 1 collaboration

S Gorressen 1 collaboration

S Heitmeier 1 collaboration

C Helten 1 collaboration

A Polzin 1 collaboration

C Jung 1 collaboration

M Kelm 1 collaboration

A C Fender 1 collaboration

U Flögel 1 collaboration

M Grandoch 1 collaboration

Theresa Schneider 1 collaboration

Johannes Stegbauer 1 collaboration

Steffen Massberg 1 collaboration

Stephen Gerfer 1 collaboration

Kathrin Feldmann 1 collaboration

Sören Twarock 1 collaboration

Sonja Hartwig 1 collaboration

Stefan Lehr 1 collaboration

Meike Klier 1 collaboration

Irena Krüger 1 collaboration

Sabine Kahl 1 collaboration

Margitta Elvers 1 collaboration

Michael Roden 1 collaboration

Jens W Fischer 1 collaboration

Stephan Sixt 1 collaboration

Christophe Vandenbriele 1 collaboration

Tim Balthazar 1 collaboration

Tom Adriaenssens 1 collaboration

Thomas Vanassche 1 collaboration

Bart Meyns 1 collaboration

Vasileios Panoulas 1 collaboration

Maria Monteagudo-Vela 1 collaboration

Deepa Arachchillage 1 collaboration

Stefan Janssens 1 collaboration

Clemens Scherer 1 collaboration

Martin Orban 1 collaboration

Patrick Horn 1 collaboration

Susanna Price 1 collaboration

Ralf Westenfeld 1 collaboration