Brooke Szczesny

Affiliations

Department of Medicine, Johns Hopkins University, Baltimore, MD, USA.

Publications (13)

Multi-omics in nasal epithelium reveals three axes of dysregulation for asthma risk in the African Diaspora populations.

Nature communications

Avec: Brooke Szczesny , Meher Preethi Boorgula , Sameer Chavan , Monica Campbell , Randi K Johnson , Kai Kammers , Emma E Thompson , Madison S Cox , Gautam Shankar , Corey Cox , Andréanne Morin , Wendy Lorizio , Michelle Daya , Samir N P Kelada , Terri H Beaty , Ayo P Doumatey , Alvaro A Cruz , Harold Watson , Edward T Naureckas , B Louise Giles , Ganiyu A Arinola , Olumide Sogaolu , Adegoke G Falade , Nadia N Hansel , Ivana V Yang , Christopher O Olopade , Charles N Rotimi , R Clive Landis , Camila A Figueiredo , Matthew C Altman , Eimear Kenny , Ingo Ruczinski , Andrew H Liu , Carole Ober , Margaret A Taub , Kathleen C Barnes , Rasika A Mathias

African-specific alleles modify risk for asthma at the 17q12-q21 locus in African Americans.

Genome medicine

Avec: Charles Washington , Matthew Dapas , Arjun Biddanda , Kevin M Magnaye , Ivy Aneas , Britney A Helling , Brooke Szczesny , Meher Preethi Boorgula , Margaret A Taub , Eimear Kenny , Rasika A Mathias , Kathleen C Barnes , Auteur inconnu , Gurjit K Khurana Hershey , Carolyn M Kercsmar , Jessica D Gereige , Melanie Makhija , Rebecca S Gruchalla , Michelle A Gill , Andrew H Liu , Deepa Rastogi , William Busse , Peter J Gergen , Cynthia M Visness , Diane R Gold , Tina Hartert , Christine C Johnson , Robert F Lemanske , Fernando D Martinez , Rachel L Miller , Dennis Ownby , Christine M Seroogy , Anne L Wright , Edward M Zoratti , Leonard B Bacharier , Meyer Kattan , George T O'Connor , Robert A Wood , Marcelo A Nobrega , Matthew C Altman , Daniel J Jackson , James E Gern , Christopher G McKennan , Carole Ober

Ligand-induced gene activation is associated with oxidative genome damage whose repair is required for transcription.

Proceedings of the National Academy of Sciences of the United States of America

Avec: Shiladitya Sengupta , Haibo Wang , Chunying Yang , Bartosz Szczesny , Muralidhar L Hegde , Sankar Mitra

The PARP inhibitor olaparib exerts beneficial effects in mice subjected to cecal ligature and puncture and in cells subjected to oxidative stress without impairing DNA integrity: A potential opportunity for repurposing a clinically used oncological drug for the experimental therapy of sepsis.

Pharmacological research

Avec: Akbar Ahmad , Juliana de Camargo Vieira , Aline Haas de Mello , Thais Martins de Lima , Suely Kubo Ariga , Denise Frediani Barbeiro , Hermes Vieira Barbeiro , Bartosz Szczesny , Gábor Törö , Nadiya Druzhyna , Elisa B Randi , Michela Marcatti , Tracy Toliver-Kinsky , András Kiss , Lucas Liaudet , Reinaldo Salomao , Francisco Garcia Soriano , Csaba Szabo

Protocol for inducing varying TBI severity in a mouse model using a closed-head, weight-drop, impact-induced acceleration mechanism.

STAR protocols

Avec: Javier Allende Labastida , Massoud Motamedi , Ping Wu , Bartosz Szczesny

Effects of the Poly(ADP-Ribose) Polymerase Inhibitor Olaparib in Cerulein-Induced Pancreatitis.

Shock (Augusta, Ga.)

Avec: Akbar Ahmad , Aline Haas De Mello , Bartosz Szczesny , Gábor Törö , Michela Marcatti , Nadiya Druzhyna , Lucas Liaudet , Stefano Tarantini , Reinaldo Salomao , Francisco Garcia Soriano , Csaba Szabo

Frontiers in microbiology

Avec: Angela Marie C Ferelli , Samantha Bolten , Brooke Szczesny , Shirley A Micallef

Quantification of Circulating Cell Free Mitochondrial DNA in Extracellular Vesicles with PicoGreen™ in Liquid Biopsies: Fast Assessment of Disease/Trauma Severity.

Cells

Avec: Michela Marcatti , Jamal Saada , Ikenna Okereke , Charles E Wade , Stefan H Bossmann , Massoud Motamedi , Bartosz Szczesny

Oxidative stress induces Z-DNA-binding protein 1-dependent activation of microglia via mtDNA released from retinal pigment epithelial cells.

The Journal of biological chemistry

Avec: Jamal Saada , Ryan J McAuley , Michela Marcatti , Tony Zifeng Tang , Massoud Motamedi , Bartosz Szczesny

Serum amyloid A and mitochondrial DNA in extracellular vesicles are novel markers for detecting traumatic brain injury in a mouse model.

iScience

Avec: Tony Z Tang , Yingxin Zhao , Deepesh Agarwal , Aabila Tharzeen , Igor Patrikeev , Yuanyi Zhang , Jana DeJesus , Stefan H Bossmann , Balasubramaniam Natarajan , Massoud Motamedi , Bartosz Szczesny

Cardiac Dysfunction after Burn Injury: Role of the AMPK-SIRT1-PGC1α-NFE2L2-ARE Pathway.

Journal of the American College of Surgeons

Avec: Jake J Wen , Claire B Cummins , Bartosz Szczesny , Ravi S Radhakrishnan

Non-Invasive Evaluation of Retinal Vascular Alterations in a Mouse Model of Optic Neuritis Using Laser Speckle Flowgraphy and Optical Coherence Tomography Angiography.

Cells

Avec: Seth E Buscho , Fan Xia , Shuizhen Shi , Jonathan L Lin , Bartosz Szczesny , Wenbo Zhang , Massoud Motamedi , Hua Liu

In vitro reconstitution reveals a key role of human mitochondrial EXOG in RNA primer processing.

Nucleic acids research

Avec: Anna Karlowicz , Andrzej B Dubiel , Jolanta Czerwinska , Adela Bledea , Piotr Purzycki , Marta Grzelewska , Ryan J McAuley , Roman J Szczesny , Gabriela Brzuska , Ewelina Krol , Bartosz Szczesny , Michal R Szymanski

Réseau de co-auteurs

Bartosz Szczesny 10 collaborations

Massoud Motamedi 5 collaborations

Michela Marcatti 4 collaborations

Meher Preethi Boorgula 2 collaborations

Matthew C Altman 2 collaborations

Eimear Kenny 2 collaborations

Andrew H Liu 2 collaborations

Carole Ober 2 collaborations

Margaret A Taub 2 collaborations

Kathleen C Barnes 2 collaborations

Rasika A Mathias 2 collaborations

Akbar Ahmad 2 collaborations

Gábor Törö 2 collaborations

Nadiya Druzhyna 2 collaborations

Lucas Liaudet 2 collaborations

Reinaldo Salomao 2 collaborations

Francisco Garcia Soriano 2 collaborations

Csaba Szabo 2 collaborations

Jamal Saada 2 collaborations

Stefan H Bossmann 2 collaborations

Ryan J McAuley 2 collaborations

Sameer Chavan 1 collaboration

Monica Campbell 1 collaboration

Randi K Johnson 1 collaboration

Kai Kammers 1 collaboration

Emma E Thompson 1 collaboration

Madison S Cox 1 collaboration

Gautam Shankar 1 collaboration

Corey Cox 1 collaboration

Andréanne Morin 1 collaboration

Wendy Lorizio 1 collaboration

Michelle Daya 1 collaboration

Samir N P Kelada 1 collaboration

Terri H Beaty 1 collaboration

Ayo P Doumatey 1 collaboration

Alvaro A Cruz 1 collaboration

Harold Watson 1 collaboration

Edward T Naureckas 1 collaboration

B Louise Giles 1 collaboration

Ganiyu A Arinola 1 collaboration

Olumide Sogaolu 1 collaboration

Adegoke G Falade 1 collaboration

Nadia N Hansel 1 collaboration

Ivana V Yang 1 collaboration

Christopher O Olopade 1 collaboration

Charles N Rotimi 1 collaboration

R Clive Landis 1 collaboration

Camila A Figueiredo 1 collaboration

Ingo Ruczinski 1 collaboration

Charles Washington 1 collaboration

Matthew Dapas 1 collaboration

Arjun Biddanda 1 collaboration

Kevin M Magnaye 1 collaboration

Ivy Aneas 1 collaboration

Britney A Helling 1 collaboration

None None 1 collaboration

Gurjit K Khurana Hershey 1 collaboration

Carolyn M Kercsmar 1 collaboration

Jessica D Gereige 1 collaboration

Melanie Makhija 1 collaboration

Rebecca S Gruchalla 1 collaboration

Michelle A Gill 1 collaboration

Deepa Rastogi 1 collaboration

William Busse 1 collaboration

Peter J Gergen 1 collaboration

Cynthia M Visness 1 collaboration

Diane R Gold 1 collaboration

Tina Hartert 1 collaboration

Christine C Johnson 1 collaboration

Robert F Lemanske 1 collaboration

Fernando D Martinez 1 collaboration

Rachel L Miller 1 collaboration

Dennis Ownby 1 collaboration

Christine M Seroogy 1 collaboration

Anne L Wright 1 collaboration

Edward M Zoratti 1 collaboration

Leonard B Bacharier 1 collaboration

Meyer Kattan 1 collaboration

George T O'Connor 1 collaboration

Robert A Wood 1 collaboration

Marcelo A Nobrega 1 collaboration

Daniel J Jackson 1 collaboration

James E Gern 1 collaboration

Christopher G McKennan 1 collaboration

Shiladitya Sengupta 1 collaboration

Haibo Wang 1 collaboration

Chunying Yang 1 collaboration

Muralidhar L Hegde 1 collaboration

Sankar Mitra 1 collaboration

Juliana de Camargo Vieira 1 collaboration

Aline Haas de Mello 1 collaboration

Thais Martins de Lima 1 collaboration

Suely Kubo Ariga 1 collaboration

Denise Frediani Barbeiro 1 collaboration

Hermes Vieira Barbeiro 1 collaboration

Elisa B Randi 1 collaboration

Tracy Toliver-Kinsky 1 collaboration

András Kiss 1 collaboration

Javier Allende Labastida 1 collaboration

Ping Wu 1 collaboration

Aline Haas De Mello 1 collaboration

Stefano Tarantini 1 collaboration

Angela Marie C Ferelli 1 collaboration

Samantha Bolten 1 collaboration

Shirley A Micallef 1 collaboration

Ikenna Okereke 1 collaboration

Charles E Wade 1 collaboration

Tony Zifeng Tang 1 collaboration

Tony Z Tang 1 collaboration

Yingxin Zhao 1 collaboration

Deepesh Agarwal 1 collaboration

Aabila Tharzeen 1 collaboration

Igor Patrikeev 1 collaboration

Yuanyi Zhang 1 collaboration

Jana DeJesus 1 collaboration

Balasubramaniam Natarajan 1 collaboration

Jake J Wen 1 collaboration

Claire B Cummins 1 collaboration

Ravi S Radhakrishnan 1 collaboration

Seth E Buscho 1 collaboration

Fan Xia 1 collaboration

Shuizhen Shi 1 collaboration

Jonathan L Lin 1 collaboration

Wenbo Zhang 1 collaboration

Hua Liu 1 collaboration

Anna Karlowicz 1 collaboration

Andrzej B Dubiel 1 collaboration

Jolanta Czerwinska 1 collaboration

Adela Bledea 1 collaboration

Piotr Purzycki 1 collaboration

Marta Grzelewska 1 collaboration

Roman J Szczesny 1 collaboration

Gabriela Brzuska 1 collaboration

Ewelina Krol 1 collaboration

Michal R Szymanski 1 collaboration