Andre Lechel

Affiliations

Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany.

Publications (21)

Author Correction: Epigenetic stress responses induce muscle stem-cell ageing by Hoxa9 developmental signals.

Nature

Avec: Simon Schwörer , Friedrich Becker , Christian Feller , Ali H Baig , Ute Köber , Henriette Henze , Johann M Kraus , Beibei Xin , André Lechel , Daniel B Lipka , Christy S Varghese , Manuel Schmidt , Remo Rohs , Ruedi Aebersold , Kay L Medina , Hans A Kestler , Francesco Neri , Julia von Maltzahn , Stefan Tümpel , K Lenhard Rudolph

Pancreatic cancer-derived organoids - a disease modeling tool to predict drug response.

United European gastroenterology journal

Avec: Pierre-Olivier Frappart , Karolin Walter , Johann Gout , Alica K Beutel , Mareen Morawe , Frank Arnold , Markus Breunig , Thomas Fe Barth , Ralf Marienfeld , Lucas Schulte , Thomas Ettrich , Thilo Hackert , Michael Svinarenko , Reinhild Rösler , Sebastian Wiese , Heike Wiese , Lukas Perkhofer , Martin Müller , André Lechel , Bruno Sainz , Patrick C Hermann , Thomas Seufferlein , Alexander Kleger

Remodelling and Improvements in Organoid Technology to Study Liver Carcinogenesis in a Dish.

Stem cells international

Avec: Umesh Tharehalli , Michael Svinarenko , André Lechel

Aneuploidy-inducing gene knockdowns overlap with cancer mutations and identify Orp3 as a B-cell lymphoma suppressor.

Oncogene

Avec: Sospeter N Njeru , Johann Kraus , Jitendra K Meena , André Lechel , Sarah-Fee Katz , Mukesh Kumar , Uwe Knippschild , Anca Azoitei , Felix Wezel , Christian Bolenz , Frank Leithäuser , André Gollowitzer , Omid Omrani , Christian Hoischen , Andreas Koeberle , Hans A Kestler , Cagatay Günes , K Lenhard Rudolph

p53-Independent Induction of p21 Fails to Control Regeneration and Hepatocarcinogenesis in a Murine Liver Injury Model.

Cellular and molecular gastroenterology and hepatology

Avec: Laura Elisa Buitrago-Molina , Silke Marhenke , Diana Becker , Robert Geffers , Timo Itzel , Andreas Teufel , Hartmut Jaeschke , André Lechel , Kristian Unger , Jovana Markovic , Amar Deep Sharma , Jens U Marquardt , Michael Saborowski , Anna Saborowski , Arndt Vogel

Telomeres and Telomerase in the Development of Liver Cancer.

Cancers

Avec: Lena In der Stroth , Umesh Tharehalli , Cagatay Günes , André Lechel

Author Correction: Cdkn1a deletion improves stem cell function and lifespan of mice with dysfunctional telomeres without accelerating cancer formation.

Nature genetics

Avec: Aaheli Roy Choudhury , Zhenyu Ju , Meta W Djojosubroto , Andrea Schienke , Andre Lechel , Sonja Schaetzlein , Hong Jiang , Anna Stepczynska , Chunfang Wang , Jan Buer , Han-Woong Lee , Thomas von Zglinicki , Arnold Ganser , Peter Schirmacher , Hiromitsu Nakauchi , K Lenhard Rudolph

IFN-γ treatment protocol for MHC-I

Journal for immunotherapy of cancer

Avec: Katja Stifter , Jana Krieger , Leonie Ruths , Johann Gout , Medhanie Mulaw , Andre Lechel , Alexander Kleger , Thomas Seufferlein , Martin Wagner , Reinhold Schirmbeck

Synergistic targeting and resistance to PARP inhibition in DNA damage repair-deficient pancreatic cancer.

Gut

Avec: Johann Gout , Lukas Perkhofer , Mareen Morawe , Frank Arnold , Michaela Ihle , Stephanie Biber , Sebastian Lange , Elodie Roger , Johann M Kraus , Katja Stifter , Stephan A Hahn , Andrea Zamperone , Thomas Engleitner , Martin Müller , Karolin Walter , Eva Rodriguez-Aznar , Bruno Sainz , Patrick C Hermann , Elisabeth Hessmann , Sebastian Müller , Ninel Azoitei , André Lechel , Stefan Liebau , Martin Wagner , Diane M Simeone , Hans A Kestler , Thomas Seufferlein , Lisa Wiesmüller , Roland Rad , Pierre-Olivier Frappart , Alexander Kleger

Protein Kinase D1, Reduced in Human Pancreatic Tumors, Increases Secretion of Small Extracellular Vesicles From Cancer Cells That Promote Metastasis to Lung in Mice.

Gastroenterology

Avec: Milena Armacki , Sandra Polaschek , Mareike Waldenmaier , Mareen Morawe , Claudia Ruhland , Rebecca Schmid , André Lechel , Umesh Tharehalli , Christoph Steup , Yasin Bektas , Hongxia Li , Johann M Kraus , Hans A Kestler , Stephan Kruger , Steffen Ormanns , Paul Walther , Tim Eiseler , Thomas Seufferlein

An IKK/NF-κB Activation/p53 Deletion Sequence Drives Liver Carcinogenesis and Tumor Differentiation.

Cancers

Avec: Michael Svinarenko , Sarah-Fee Katz , Umesh Tharehalli , Medhanie A Mulaw , Harald J Maier , Yoshiaki Sunami , Sarah K Fischer , Yuexin Chen , Sabine Heurich , Lena Erkert , Andrea Tannapfel , Thomas Wirth , Reinhold Schirmbeck , Thomas Seufferlein , André Lechel

Small Extracellular Vesicles Propagate the Inflammatory Response After Trauma.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Avec: Tanja Seibold , Jonathan Schönfelder , Florian Weeber , André Lechel , Milena Armacki , Mareike Waldenmaier , Christoph Wille , Annette Palmer , Rebecca Halbgebauer , Ebru Karasu , Markus Huber-Lang , Miriam Kalbitz , Peter Radermacher , Stephan Paschke , Thomas Seufferlein , Tim Eiseler

Telomerase and Pluripotency Factors Jointly Regulate Stemness in Pancreatic Cancer Stem Cells.

Cancers

Avec: Karolin Walter , Eva Rodriguez-Aznar , Monica S Ventura Ferreira , Pierre-Olivier Frappart , Tabea Dittrich , Kanishka Tiwary , Sabine Meessen , Laura Lerma , Nora Daiss , Lucas-Alexander Schulte , Zeynab Najafova , Frank Arnold , Valentyn Usachov , Ninel Azoitei , Mert Erkan , Andre Lechel , Tim H Brümmendorf , Thomas Seufferlein , Alexander Kleger , Enrique Tabarés , Cagatay Günes , Steven A Johnsen , Fabian Beier , Bruno Sainz , Patrick C Hermann

Molecular features and vulnerabilities of recurrent chordomas.

Journal of experimental & clinical cancer research : CR

Avec: Carolin Seeling , André Lechel , Michael Svinarenko , Peter Möller , Thomas F E Barth , Kevin Mellert

CARD9 Forms an Alternative CBM Complex in Richter Syndrome.

Cancers

Avec: Julia Maier , André Lechel , Ralf Marienfeld , Thomas F E Barth , Peter Möller , Kevin Mellert

Elevated Hedgehog activity contributes to attenuated DNA damage responses in aged hematopoietic cells.

Leukemia

Avec: Annika Scheffold , Ali H Baig , Zhiyang Chen , Sarah E von Löhneysen , Friedrich Becker , Yohei Morita , Alush I Avila , Marco Groth , André Lechel , Florian Schmid , Johann M Kraus , Hans A Kestler , Stephan Stilgenbauer , Melanie Philipp , Martin D Burkhalter

Iron at the Interface of Hepatocellular Carcinoma.

International journal of molecular sciences

Avec: Rossana Paganoni , André Lechel , Maja Vujic Spasic

RINT1 Regulates SUMOylation and the DNA Damage Response to Preserve Cellular Homeostasis in Pancreatic Cancer.

Cancer research

Avec: Frank Arnold , Johann Gout , Heike Wiese , Stephanie E Weissinger , Elodie Roger , Lukas Perkhofer , Karolin Walter , Jeanette Scheible , Caterina Prelli Bozzo , André Lechel , Thomas J Ettrich , Ninel Azoitei , Li Hao , Axel Fürstberger , Ewa K Kaminska , Konstantin M J Sparrer , Volker Rasche , Sebastian Wiese , Hans A Kestler , Peter Möller , Thomas Seufferlein , Pierre-Olivier Frappart , Alexander Kleger

Functional Genomic Screening During Somatic Cell Reprogramming Identifies DKK3 as a Roadblock of Organ Regeneration.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Avec: Frank Arnold , Pallavi U Mahaddalkar , Johann M Kraus , Xiaowei Zhong , Wendy Bergmann , Dharini Srinivasan , Johann Gout , Elodie Roger , Alica K Beutel , Eugen Zizer , Umesh Tharehalli , Nora Daiss , Ronan Russell , Lukas Perkhofer , Rupert Oellinger , Qiong Lin , Ninel Azoitei , Frank-Ulrich Weiss , Markus M Lerch , Stefan Liebau , Sarah-Fee Katz , André Lechel , Roland Rad , Thomas Seufferlein , Hans A Kestler , Michael Ott , Amar Deep Sharma , Patrick C Hermann , Alexander Kleger

Loss of SUV420H2-Dependent Chromatin Compaction Drives Right-Sided Colon Cancer Progression.

Gastroenterology

Avec: Verawan Boonsanay , Mohammed H Mosa , Mario Looso , Dieter Weichenhan , Fatih Ceteci , Lorenz Pudelko , Andre Lechel , Christian S Michel , Carsten Künne , Henner F Farin , Christoph Plass , Florian R Greten

CD8 T cell-mediated depletion of HBV surface-antigen-expressing, bilineal-differentiated liver carcinoma cells generates highly aggressive escape variants.

Oncoimmunology

Avec: Na Qiu , Akshaya Srikanth , Medhanie Mulaw , Umesh Tharehalli , Shanthiya Selvachandran , Martin Wagner , Thomas Seufferlein , Katja Stifter , André Lechel , Reinhold Schirmbeck

Réseau de co-auteurs

André Lechel 17 collaborations

Thomas Seufferlein 10 collaborations

Hans A Kestler 7 collaborations

Alexander Kleger 6 collaborations

Umesh Tharehalli 6 collaborations

Johann M Kraus 5 collaborations

Johann Gout 5 collaborations

Frank Arnold 5 collaborations

Pierre-Olivier Frappart 4 collaborations

Karolin Walter 4 collaborations

Michael Svinarenko 4 collaborations

Lukas Perkhofer 4 collaborations

Patrick C Hermann 4 collaborations

Ninel Azoitei 4 collaborations

K Lenhard Rudolph 3 collaborations

Mareen Morawe 3 collaborations

Bruno Sainz 3 collaborations

Sarah-Fee Katz 3 collaborations

Cagatay Günes 3 collaborations

Katja Stifter 3 collaborations

Martin Wagner 3 collaborations

Reinhold Schirmbeck 3 collaborations

Elodie Roger 3 collaborations

Peter Möller 3 collaborations

Friedrich Becker 2 collaborations

Ali H Baig 2 collaborations

Alica K Beutel 2 collaborations

Ralf Marienfeld 2 collaborations

Sebastian Wiese 2 collaborations

Heike Wiese 2 collaborations

Martin Müller 2 collaborations

Amar Deep Sharma 2 collaborations

Medhanie Mulaw 2 collaborations

Eva Rodriguez-Aznar 2 collaborations

Stefan Liebau 2 collaborations

Roland Rad 2 collaborations

Milena Armacki 2 collaborations

Mareike Waldenmaier 2 collaborations

Tim Eiseler 2 collaborations

Nora Daiss 2 collaborations

Thomas F E Barth 2 collaborations

Kevin Mellert 2 collaborations

Simon Schwörer 1 collaboration

Christian Feller 1 collaboration

Ute Köber 1 collaboration

Henriette Henze 1 collaboration

Beibei Xin 1 collaboration

Daniel B Lipka 1 collaboration

Christy S Varghese 1 collaboration

Manuel Schmidt 1 collaboration

Remo Rohs 1 collaboration

Ruedi Aebersold 1 collaboration

Kay L Medina 1 collaboration

Francesco Neri 1 collaboration

Julia von Maltzahn 1 collaboration

Stefan Tümpel 1 collaboration

Markus Breunig 1 collaboration

Thomas Fe Barth 1 collaboration

Lucas Schulte 1 collaboration

Thomas Ettrich 1 collaboration

Thilo Hackert 1 collaboration

Reinhild Rösler 1 collaboration

Sospeter N Njeru 1 collaboration

Johann Kraus 1 collaboration

Jitendra K Meena 1 collaboration

Mukesh Kumar 1 collaboration

Uwe Knippschild 1 collaboration

Anca Azoitei 1 collaboration

Felix Wezel 1 collaboration

Christian Bolenz 1 collaboration

Frank Leithäuser 1 collaboration

André Gollowitzer 1 collaboration

Omid Omrani 1 collaboration

Christian Hoischen 1 collaboration

Andreas Koeberle 1 collaboration

Laura Elisa Buitrago-Molina 1 collaboration

Silke Marhenke 1 collaboration

Diana Becker 1 collaboration

Robert Geffers 1 collaboration

Timo Itzel 1 collaboration

Andreas Teufel 1 collaboration

Hartmut Jaeschke 1 collaboration

Kristian Unger 1 collaboration

Jovana Markovic 1 collaboration

Jens U Marquardt 1 collaboration

Michael Saborowski 1 collaboration

Anna Saborowski 1 collaboration

Arndt Vogel 1 collaboration

Lena In der Stroth 1 collaboration

Aaheli Roy Choudhury 1 collaboration

Zhenyu Ju 1 collaboration

Meta W Djojosubroto 1 collaboration

Andrea Schienke 1 collaboration

Sonja Schaetzlein 1 collaboration

Hong Jiang 1 collaboration

Anna Stepczynska 1 collaboration

Chunfang Wang 1 collaboration

Jan Buer 1 collaboration

Han-Woong Lee 1 collaboration

Thomas von Zglinicki 1 collaboration

Arnold Ganser 1 collaboration

Peter Schirmacher 1 collaboration

Hiromitsu Nakauchi 1 collaboration

Jana Krieger 1 collaboration

Leonie Ruths 1 collaboration

Michaela Ihle 1 collaboration

Stephanie Biber 1 collaboration

Sebastian Lange 1 collaboration

Stephan A Hahn 1 collaboration

Andrea Zamperone 1 collaboration

Thomas Engleitner 1 collaboration

Elisabeth Hessmann 1 collaboration

Sebastian Müller 1 collaboration

Diane M Simeone 1 collaboration

Lisa Wiesmüller 1 collaboration

Sandra Polaschek 1 collaboration

Claudia Ruhland 1 collaboration

Rebecca Schmid 1 collaboration

Christoph Steup 1 collaboration

Yasin Bektas 1 collaboration

Hongxia Li 1 collaboration

Stephan Kruger 1 collaboration

Steffen Ormanns 1 collaboration

Paul Walther 1 collaboration

Medhanie A Mulaw 1 collaboration

Harald J Maier 1 collaboration

Yoshiaki Sunami 1 collaboration

Sarah K Fischer 1 collaboration

Yuexin Chen 1 collaboration

Sabine Heurich 1 collaboration

Lena Erkert 1 collaboration

Andrea Tannapfel 1 collaboration

Thomas Wirth 1 collaboration

Tanja Seibold 1 collaboration

Jonathan Schönfelder 1 collaboration

Florian Weeber 1 collaboration

Christoph Wille 1 collaboration

Annette Palmer 1 collaboration

Rebecca Halbgebauer 1 collaboration

Ebru Karasu 1 collaboration

Markus Huber-Lang 1 collaboration

Miriam Kalbitz 1 collaboration

Peter Radermacher 1 collaboration

Stephan Paschke 1 collaboration

Monica S Ventura Ferreira 1 collaboration

Tabea Dittrich 1 collaboration

Kanishka Tiwary 1 collaboration

Sabine Meessen 1 collaboration

Laura Lerma 1 collaboration

Lucas-Alexander Schulte 1 collaboration

Zeynab Najafova 1 collaboration

Valentyn Usachov 1 collaboration

Mert Erkan 1 collaboration

Tim H Brümmendorf 1 collaboration

Enrique Tabarés 1 collaboration

Steven A Johnsen 1 collaboration

Fabian Beier 1 collaboration

Carolin Seeling 1 collaboration

Julia Maier 1 collaboration

Annika Scheffold 1 collaboration

Zhiyang Chen 1 collaboration

Sarah E von Löhneysen 1 collaboration

Yohei Morita 1 collaboration

Alush I Avila 1 collaboration

Marco Groth 1 collaboration

Florian Schmid 1 collaboration

Stephan Stilgenbauer 1 collaboration

Melanie Philipp 1 collaboration

Martin D Burkhalter 1 collaboration

Rossana Paganoni 1 collaboration

Maja Vujic Spasic 1 collaboration

Stephanie E Weissinger 1 collaboration

Jeanette Scheible 1 collaboration

Caterina Prelli Bozzo 1 collaboration

Thomas J Ettrich 1 collaboration

Li Hao 1 collaboration

Axel Fürstberger 1 collaboration

Ewa K Kaminska 1 collaboration

Konstantin M J Sparrer 1 collaboration

Volker Rasche 1 collaboration

Pallavi U Mahaddalkar 1 collaboration

Xiaowei Zhong 1 collaboration

Wendy Bergmann 1 collaboration

Dharini Srinivasan 1 collaboration

Eugen Zizer 1 collaboration

Ronan Russell 1 collaboration

Rupert Oellinger 1 collaboration

Qiong Lin 1 collaboration

Frank-Ulrich Weiss 1 collaboration

Markus M Lerch 1 collaboration

Michael Ott 1 collaboration

Verawan Boonsanay 1 collaboration

Mohammed H Mosa 1 collaboration

Mario Looso 1 collaboration

Dieter Weichenhan 1 collaboration

Fatih Ceteci 1 collaboration

Lorenz Pudelko 1 collaboration

Christian S Michel 1 collaboration

Carsten Künne 1 collaboration

Henner F Farin 1 collaboration

Christoph Plass 1 collaboration

Florian R Greten 1 collaboration

Na Qiu 1 collaboration

Akshaya Srikanth 1 collaboration

Shanthiya Selvachandran 1 collaboration