Ali Roghanian

Affiliations

Koch Institute for Integrative Cancer Research and Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts. a.roghanian@soton.ac.uk aroghani@mit.edu jchen@mit.edu.
Antibody and Vaccine Group, Centre for Cancer Immunology, Cancer Sciences Unit, Faculty of Medicine, University of Southampton, Southampton, United Kingdom.
Cancer Research UK Centre, University of Southampton, Southampton, United Kindgom.

ORCID: 0000-0003-1316-4218

Publications (7)

Cyclophosphamide Enhances Cancer Antibody Immunotherapy in the Resistant Bone Marrow Niche by Modulating Macrophage FcγR Expression.

Cancer immunology research

Avec: Ali Roghanian , Guangan Hu , Christopher Fraser , Maneesh Singh , Russell B Foxall , Matthew J Meyer , Emma Lees , Heather Huet , Martin J Glennie , Stephen A Beers , Sean H Lim , Margaret Ashton-Key , Stephen M Thirdborough , Mark S Cragg , Jianzhu Chen

LILRB3 (ILT5) is a myeloid cell checkpoint that elicits profound immunomodulation.

JCI insight

Avec: Muchaala Yeboah , Charys Papagregoriou , Des C Jones , H T Claude Chan , Guangan Hu , Justine S McPartlan , Torbjörn Schiött , Ulrika Mattson , C Ian Mockridge , Ulla-Carin Tornberg , Björn Hambe , Anne Ljungars , Mikael Mattsson , Ivo Tews , Martin J Glennie , Stephen M Thirdborough , John Trowsdale , Björn Frendeus , Jianzhu Chen , Mark S Cragg , Ali Roghanian

FcγRIIB controls antibody-mediated target cell depletion by ITIM-independent mechanisms.

Cell reports

Avec: Alexander P Simpson , Ali Roghanian , Robert J Oldham , H T Claude Chan , Christine A Penfold , Hyung J Kim , Tatyana Inzhelevskaya , C Ian Mockridge , Kerry L Cox , Yury D Bogdanov , Sonya James , Alison L Tutt , Daniel Rycroft , Peter Morley , Lekh N Dahal , Ingrid Teige , Björn Frendeus , Stephen A Beers , Mark S Cragg

Towards a better understanding of human iNKT cell subpopulations for improved clinical outcomes.

Frontiers in immunology

Avec: Alex Look , Daniel Burns , Ivo Tews , Ali Roghanian , Salah Mansour

Human leukocyte immunoglobulin-like receptors in health and disease.

Frontiers in immunology

Avec: Silvia Redondo-García , Christopher Barritt , Charys Papagregoriou , Muchaala Yeboah , Björn Frendeus , Mark S Cragg , Ali Roghanian

HIF activation enhances FcγRIIb expression on mononuclear phagocytes impeding tumor targeting antibody immunotherapy.

Journal of experimental & clinical cancer research : CR

Avec: Khiyam Hussain , Rena Liu , Rosanna C G Smith , Kri T J Müller , Mohammadmersad Ghorbani , Sofia Macari , Kirstie L S Cleary , Robert J Oldham , Russell B Foxall , Sonya James , Steven G Booth , Tom Murray , Lekh N Dahal , Chantal E Hargreaves , Robert S Kemp , Jemma Longley , James Douglas , Hannah Markham , Serena J Chee , Richard J Stopforth , Ali Roghanian , Matthew J Carter , Christian H Ottensmeier , Bjorn Frendéus , Ramsey I Cutress , Ruth R French , Martin J Glennie , Jonathan C Strefford , Stephen M Thirdborough , Stephen A Beers , Mark S Cragg

Human inhibitory leukocyte Ig-like receptors: from immunotolerance to immunotherapy.

JCI insight

Avec: Calvin D De Louche , Ali Roghanian

Réseau de co-auteurs

Mark S Cragg 5 collaborations

Martin J Glennie 3 collaborations

Stephen A Beers 3 collaborations

Stephen M Thirdborough 3 collaborations

Björn Frendeus 3 collaborations

Guangan Hu 2 collaborations

Russell B Foxall 2 collaborations

Jianzhu Chen 2 collaborations

Muchaala Yeboah 2 collaborations

Charys Papagregoriou 2 collaborations

H T Claude Chan 2 collaborations

C Ian Mockridge 2 collaborations

Ivo Tews 2 collaborations

Robert J Oldham 2 collaborations

Sonya James 2 collaborations

Lekh N Dahal 2 collaborations

Christopher Fraser 1 collaboration

Maneesh Singh 1 collaboration

Matthew J Meyer 1 collaboration

Emma Lees 1 collaboration

Heather Huet 1 collaboration

Sean H Lim 1 collaboration

Margaret Ashton-Key 1 collaboration

Des C Jones 1 collaboration

Justine S McPartlan 1 collaboration

Torbjörn Schiött 1 collaboration

Ulrika Mattson 1 collaboration

Ulla-Carin Tornberg 1 collaboration

Björn Hambe 1 collaboration

Anne Ljungars 1 collaboration

Mikael Mattsson 1 collaboration

John Trowsdale 1 collaboration

Alexander P Simpson 1 collaboration

Christine A Penfold 1 collaboration

Hyung J Kim 1 collaboration

Tatyana Inzhelevskaya 1 collaboration

Kerry L Cox 1 collaboration

Yury D Bogdanov 1 collaboration

Alison L Tutt 1 collaboration

Daniel Rycroft 1 collaboration

Peter Morley 1 collaboration

Ingrid Teige 1 collaboration

Alex Look 1 collaboration

Daniel Burns 1 collaboration

Salah Mansour 1 collaboration

Silvia Redondo-García 1 collaboration

Christopher Barritt 1 collaboration

Khiyam Hussain 1 collaboration

Rena Liu 1 collaboration

Rosanna C G Smith 1 collaboration

Kri T J Müller 1 collaboration

Mohammadmersad Ghorbani 1 collaboration

Sofia Macari 1 collaboration

Kirstie L S Cleary 1 collaboration

Steven G Booth 1 collaboration

Tom Murray 1 collaboration

Chantal E Hargreaves 1 collaboration

Robert S Kemp 1 collaboration

Jemma Longley 1 collaboration

James Douglas 1 collaboration

Hannah Markham 1 collaboration

Serena J Chee 1 collaboration

Richard J Stopforth 1 collaboration

Matthew J Carter 1 collaboration

Christian H Ottensmeier 1 collaboration

Bjorn Frendéus 1 collaboration

Ramsey I Cutress 1 collaboration

Ruth R French 1 collaboration

Jonathan C Strefford 1 collaboration

Calvin D De Louche 1 collaboration