Alfredo Quijano-Rubio

Affiliations

Department of Biochemistry and Institute for Protein Design, University of Washington, Seattle, WA, USA.
Department of Bioengineering, University of Washington, Seattle, WA, USA.
Monod Bio, Inc., Seattle, WA, USA.

ORCID: 0000-0003-1567-9530

Publications (14)

A split, conditionally active mimetic of IL-2 reduces the toxicity of systemic cytokine therapy.

Nature biotechnology

Avec: Alfredo Quijano-Rubio , Aladdin M Bhuiyan , Huilin Yang , Isabel Leung , Elisa Bello , Lestat R Ali , Kevin Zhangxu , Jilliane Perkins , Jung-Ho Chun , Wentao Wang , Marc J Lajoie , Rashmi Ravichandran , Yun-Huai Kuo , Stephanie K Dougan , Stanley R Riddell , Jamie B Spangler , Michael Dougan , Daniel-Adriano Silva , David Baker

De novo design of tunable, pH-driven conformational changes.

Science (New York, N.Y.)

Avec: Scott E Boyken , Mark A Benhaim , Florian Busch , Mengxuan Jia , Matthew J Bick , Heejun Choi , Jason C Klima , Zibo Chen , Carl Walkey , Alexander Mileant , Aniruddha Sahasrabuddhe , Kathy Y Wei , Edgar A Hodge , Sarah Byron , Alfredo Quijano-Rubio , Banumathi Sankaran , Neil P King , Jennifer Lippincott-Schwartz , Vicki H Wysocki , Kelly K Lee , David Baker

De novo design of modular and tunable protein biosensors.

Nature

Avec: Alfredo Quijano-Rubio , Hsien-Wei Yeh , Jooyoung Park , Hansol Lee , Robert A Langan , Scott E Boyken , Marc J Lajoie , Longxing Cao , Cameron M Chow , Marcos C Miranda , Jimin Wi , Hyo Jeong Hong , Lance Stewart , Byung-Ha Oh , David Baker

A memory switch for plant synthetic biology based on the phage ϕC31 integration system.

Nucleic acids research

Avec: Joan Miquel Bernabé-Orts , Alfredo Quijano-Rubio , Marta Vazquez-Vilar , Javier Mancheño-Bonillo , Victor Moles-Casas , Sara Selma , Silvia Gianoglio , Antonio Granell , Diego Orzaez

Detection of antibodies neutralizing historical and emerging SARS-CoV-2 strains using a thermodynamically coupled de novo biosensor system.

bioRxiv : the preprint server for biology

Avec: Jason Z Zhang , Hsien-Wei Yeh , Alexandra C Walls , Basile I M Wicky , Kaiti Sprouse , Laura A VanBlargan , Rebecca Treger , Alfredo Quijano-Rubio , Minh N Pham , John C Kraft , Ian C Haydon , Wei Yang , Michelle DeWitt , Cameron Chow , Lauren Carter , Mark H Wener , Lance Stewart , David Veesler , Michael S Diamond , David Baker

The advent of de novo proteins for cancer immunotherapy.

Current opinion in chemical biology

Avec: Alfredo Quijano-Rubio , Umut Y Ulge , Carl D Walkey , Daniel-Adriano Silva

bioRxiv : the preprint server for biology

Avec: Alfredo Quijano-Rubio , Hsien-Wei Yeh , Jooyoung Park , Hansol Lee , Robert A Langan , Scott E Boyken , Marc J Lajoie , Longxing Cao , Cameron M Chow , Marcos C Miranda , Jimin Wi , Hyo Jeong Hong , Lance Stewart , Byung-Ha Oh , David Baker

De novo design of potent and selective mimics of IL-2 and IL-15.

Nature

Avec: Daniel-Adriano Silva , Shawn Yu , Umut Y Ulge , Jamie B Spangler , Kevin M Jude , Carlos Labão-Almeida , Lestat R Ali , Alfredo Quijano-Rubio , Mikel Ruterbusch , Isabel Leung , Tamara Biary , Stephanie J Crowley , Enrique Marcos , Carl D Walkey , Brian D Weitzner , Fátima Pardo-Avila , Javier Castellanos , Lauren Carter , Lance Stewart , Stanley R Riddell , Marion Pepper , Gonçalo J L Bernardes , Michael Dougan , K Christopher Garcia , David Baker

A copper switch for inducing CRISPR/Cas9-based transcriptional activation tightly regulates gene expression in Nicotiana benthamiana.

BMC biotechnology

Avec: Elena Garcia-Perez , Borja Diego-Martin , Alfredo Quijano-Rubio , Elena Moreno-Giménez , Sara Selma , Diego Orzaez , Marta Vazquez-Vilar

Production of Volatile Moth Sex Pheromones in Transgenic

Biodesign research

Avec: Rubén Mateos-Fernández , Elena Moreno-Giménez , Silvia Gianoglio , Alfredo Quijano-Rubio , Jose Gavaldá-García , Lucía Estellés , Alba Rubert , José Luis Rambla , Marta Vazquez-Vilar , Estefanía Huet , Asunción Fernández-Del-Carmen , Ana Espinosa-Ruiz , Mojca Juteršek , Sandra Vacas , Ismael Navarro , Vicente Navarro-Llopis , Jaime Primo , Diego Orzáez

Design of cell-type-specific hyperstable IL-4 mimetics via modular de novo scaffolds.

Nature chemical biology

Avec: Huilin Yang , Umut Y Ulge , Alfredo Quijano-Rubio , Zachary J Bernstein , David R Maestas , Jung-Ho Chun , Wentao Wang , Jian-Xin Lin , Kevin M Jude , Srujan Singh , Brian T Orcutt-Jahns , Peng Li , Jody Mou , Liam Chung , Yun-Huai Kuo , Yasmin H Ali , Aaron S Meyer , Warren L Grayson , Nicola M Heller , K Christopher Garcia , Warren J Leonard , Daniel-Adriano Silva , Jennifer H Elisseeff , David Baker , Jamie B Spangler

Designed protein logic to target cells with precise combinations of surface antigens.

Science (New York, N.Y.)

Avec: Marc J Lajoie , Scott E Boyken , Alexander I Salter , Jilliane Bruffey , Anusha Rajan , Robert A Langan , Audrey Olshefsky , Vishaka Muhunthan , Matthew J Bick , Mesfin Gewe , Alfredo Quijano-Rubio , JayLee Johnson , Garreck Lenz , Alisha Nguyen , Suzie Pun , Colin E Correnti , Stanley R Riddell , David Baker

Thermodynamically coupled biosensors for detecting neutralizing antibodies against SARS-CoV-2 variants.

Nature biotechnology

Avec: Jason Z Zhang , Hsien-Wei Yeh , Alexandra C Walls , Basile I M Wicky , Kaitlin R Sprouse , Laura A VanBlargan , Rebecca Treger , Alfredo Quijano-Rubio , Minh N Pham , John C Kraft , Ian C Haydon , Wei Yang , Michelle DeWitt , John E Bowen , Cameron M Chow , Lauren Carter , Rashmi Ravichandran , Mark H Wener , Lance Stewart , David Veesler , Michael S Diamond , Alexander L Greninger , David M Koelle , David Baker

Reshaping de Novo Protein Switches into Bioresponsive Materials for Biomarker, Toxin, and Viral Detection.

Advanced materials (Deerfield Beach, Fla.)

Avec: Luciana d'Amone , Giusy Matzeu , Alfredo Quijano-Rubio , Gregory P Callahan , Bradley Napier , David Baker , Fiorenzo G Omenetto

Réseau de co-auteurs

David Baker 10 collaborations

Lance Stewart 5 collaborations

Marc J Lajoie 4 collaborations

Daniel-Adriano Silva 4 collaborations

Scott E Boyken 4 collaborations

Hsien-Wei Yeh 4 collaborations

Stanley R Riddell 3 collaborations

Jamie B Spangler 3 collaborations

Robert A Langan 3 collaborations

Cameron M Chow 3 collaborations

Marta Vazquez-Vilar 3 collaborations

Lauren Carter 3 collaborations

Umut Y Ulge 3 collaborations

Huilin Yang 2 collaborations

Isabel Leung 2 collaborations

Lestat R Ali 2 collaborations

Jung-Ho Chun 2 collaborations

Wentao Wang 2 collaborations

Rashmi Ravichandran 2 collaborations

Yun-Huai Kuo 2 collaborations

Michael Dougan 2 collaborations

Matthew J Bick 2 collaborations

Jooyoung Park 2 collaborations

Hansol Lee 2 collaborations

Longxing Cao 2 collaborations

Marcos C Miranda 2 collaborations

Jimin Wi 2 collaborations

Hyo Jeong Hong 2 collaborations

Byung-Ha Oh 2 collaborations

Sara Selma 2 collaborations

Silvia Gianoglio 2 collaborations

Diego Orzaez 2 collaborations

Jason Z Zhang 2 collaborations

Alexandra C Walls 2 collaborations

Basile I M Wicky 2 collaborations

Laura A VanBlargan 2 collaborations

Rebecca Treger 2 collaborations

Minh N Pham 2 collaborations

John C Kraft 2 collaborations

Ian C Haydon 2 collaborations

Wei Yang 2 collaborations

Michelle DeWitt 2 collaborations

Mark H Wener 2 collaborations

David Veesler 2 collaborations

Michael S Diamond 2 collaborations

Carl D Walkey 2 collaborations

Kevin M Jude 2 collaborations

K Christopher Garcia 2 collaborations

Elena Moreno-Giménez 2 collaborations

Aladdin M Bhuiyan 1 collaboration

Elisa Bello 1 collaboration

Kevin Zhangxu 1 collaboration

Jilliane Perkins 1 collaboration

Stephanie K Dougan 1 collaboration

Mark A Benhaim 1 collaboration

Florian Busch 1 collaboration

Mengxuan Jia 1 collaboration

Heejun Choi 1 collaboration

Jason C Klima 1 collaboration

Zibo Chen 1 collaboration

Carl Walkey 1 collaboration

Alexander Mileant 1 collaboration

Aniruddha Sahasrabuddhe 1 collaboration

Kathy Y Wei 1 collaboration

Edgar A Hodge 1 collaboration

Sarah Byron 1 collaboration

Banumathi Sankaran 1 collaboration

Neil P King 1 collaboration

Jennifer Lippincott-Schwartz 1 collaboration

Vicki H Wysocki 1 collaboration

Kelly K Lee 1 collaboration

Joan Miquel Bernabé-Orts 1 collaboration

Javier Mancheño-Bonillo 1 collaboration

Victor Moles-Casas 1 collaboration

Antonio Granell 1 collaboration

Kaiti Sprouse 1 collaboration

Cameron Chow 1 collaboration

Shawn Yu 1 collaboration

Carlos Labão-Almeida 1 collaboration

Mikel Ruterbusch 1 collaboration

Tamara Biary 1 collaboration

Stephanie J Crowley 1 collaboration

Enrique Marcos 1 collaboration

Brian D Weitzner 1 collaboration

Fátima Pardo-Avila 1 collaboration

Javier Castellanos 1 collaboration

Marion Pepper 1 collaboration

Gonçalo J L Bernardes 1 collaboration

Elena Garcia-Perez 1 collaboration

Borja Diego-Martin 1 collaboration

Rubén Mateos-Fernández 1 collaboration

Jose Gavaldá-García 1 collaboration

Lucía Estellés 1 collaboration

Alba Rubert 1 collaboration

José Luis Rambla 1 collaboration

Estefanía Huet 1 collaboration

Asunción Fernández-Del-Carmen 1 collaboration

Ana Espinosa-Ruiz 1 collaboration

Mojca Juteršek 1 collaboration

Sandra Vacas 1 collaboration

Ismael Navarro 1 collaboration

Vicente Navarro-Llopis 1 collaboration

Jaime Primo 1 collaboration

Diego Orzáez 1 collaboration

Zachary J Bernstein 1 collaboration

David R Maestas 1 collaboration

Jian-Xin Lin 1 collaboration

Srujan Singh 1 collaboration

Brian T Orcutt-Jahns 1 collaboration

Peng Li 1 collaboration

Jody Mou 1 collaboration

Liam Chung 1 collaboration

Yasmin H Ali 1 collaboration

Aaron S Meyer 1 collaboration

Warren L Grayson 1 collaboration

Nicola M Heller 1 collaboration

Warren J Leonard 1 collaboration

Jennifer H Elisseeff 1 collaboration

Alexander I Salter 1 collaboration

Jilliane Bruffey 1 collaboration

Anusha Rajan 1 collaboration

Audrey Olshefsky 1 collaboration

Vishaka Muhunthan 1 collaboration

Mesfin Gewe 1 collaboration

JayLee Johnson 1 collaboration

Garreck Lenz 1 collaboration

Alisha Nguyen 1 collaboration

Suzie Pun 1 collaboration

Colin E Correnti 1 collaboration

Kaitlin R Sprouse 1 collaboration

John E Bowen 1 collaboration

Alexander L Greninger 1 collaboration

David M Koelle 1 collaboration

Luciana d'Amone 1 collaboration

Giusy Matzeu 1 collaboration

Gregory P Callahan 1 collaboration

Bradley Napier 1 collaboration

Fiorenzo G Omenetto 1 collaboration