Alexander Schepsky

Affiliations

Stem Cell Research Unit, Biomedical Center, University of Iceland, 101 Reykjavik, Iceland.

ORCID: 0000-0003-3671-477X

Publications (6)

Aminopeptidase Expression in Multiple Myeloma Associates with Disease Progression and Sensitivity to Melflufen.

Cancers

Avec: Juho J Miettinen , Romika Kumari , Gunnhildur Asta Traustadottir , Maiju-Emilia Huppunen , Philipp Sergeev , Muntasir M Majumder , Alexander Schepsky , Thorarinn Gudjonsson , Juha Lievonen , Despina Bazou , Paul Dowling , Peter O Gorman , Ana Slipicevic , Pekka Anttila , Raija Silvennoinen , Nina N Nupponen , Fredrik Lehmann , Caroline A Heckman

Tuning Transcription Factor Availability through Acetylation-Mediated Genomic Redistribution.

Molecular cell

Avec: Pakavarin Louphrasitthiphol , Robert Siddaway , Alessia Loffreda , Vivian Pogenberg , Hans Friedrichsen , Alexander Schepsky , Zhiqiang Zeng , Min Lu , Thomas Strub , Rasmus Freter , Richard Lisle , Eda Suer , Benjamin Thomas , Benjamin Schuster-Böckler , Panagis Filippakopoulos , Mark Middleton , Xin Lu , E Elizabeth Patton , Irwin Davidson , Jean-Philippe Lambert , Matthias Wilmanns , Eiríkur Steingrímsson , Davide Mazza , Colin R Goding

ECM1 secreted by HER2-overexpressing breast cancer cells promotes formation of a vascular niche accelerating cancer cell migration and invasion.

Laboratory investigation; a journal of technical methods and pathology

Avec: Sophie Sarah Steinhaeuser , Erika Morera , Zuzana Budkova , Alexander Schepsky , Qiong Wang , Ottar Rolfsson , Angela Riedel , Aileen Krueger , Bylgja Hilmarsdottir , Gunhild Mari Maelandsmo , Bryndis Valdimarsdottir , Anna Karen Sigurdardottir , Bjarni Agnar Agnarsson , Jon Gunnlaugur Jonasson , Saevar Ingthorsson , Gunnhildur Asta Traustadottir , Thordur Oskarsson , Thorarinn Gudjonsson

Melflufen, a peptide-conjugated alkylator, is an efficient anti-neo-plastic drug in breast cancer cell lines.

Cancer medicine

Avec: Alexander Schepsky , Gunnhildur Asta Traustadottir , Jon Petur Joelsson , Saevar Ingthorsson , Jennifer Kricker , Jon Thor Bergthorsson , Arni Asbjarnarson , Thorkell Gudjonsson , Nina Nupponen , Ana Slipicevic , Fredrik Lehmann , Thorarinn Gudjonsson

Subcellular localization and stability of MITF are modulated by the bHLH-Zip domain.

Pigment cell & melanoma research

Avec: Valerie Fock , Sigurdur Runar Gudmundsson , Hilmar Orn Gunnlaugsson , Jon August Stefansson , Vivien Ionasz , Alexander Schepsky , Jade Viarigi , Indridi Einar Reynisson , Vivian Pogenberg , Matthias Wilmanns , Margret Helga Ogmundsdottir , Eirikur Steingrimsson

Acetylation reprograms MITF target selectivity and residence time.

Nature communications

Avec: Pakavarin Louphrasitthiphol , Alessia Loffreda , Vivian Pogenberg , Sarah Picaud , Alexander Schepsky , Hans Friedrichsen , Zhiqiang Zeng , Anahita Lashgari , Benjamin Thomas , E Elizabeth Patton , Matthias Wilmanns , Panagis Filippakopoulos , Jean-Philippe Lambert , Eiríkur Steingrímsson , Davide Mazza , Colin R Goding

Réseau de co-auteurs

Gunnhildur Asta Traustadottir 3 collaborations

Thorarinn Gudjonsson 3 collaborations

Vivian Pogenberg 3 collaborations

Matthias Wilmanns 3 collaborations

Ana Slipicevic 2 collaborations

Fredrik Lehmann 2 collaborations

Pakavarin Louphrasitthiphol 2 collaborations

Alessia Loffreda 2 collaborations

Hans Friedrichsen 2 collaborations

Zhiqiang Zeng 2 collaborations

Benjamin Thomas 2 collaborations

Panagis Filippakopoulos 2 collaborations

E Elizabeth Patton 2 collaborations

Jean-Philippe Lambert 2 collaborations

Eiríkur Steingrímsson 2 collaborations

Davide Mazza 2 collaborations

Colin R Goding 2 collaborations

Saevar Ingthorsson 2 collaborations

Juho J Miettinen 1 collaboration

Romika Kumari 1 collaboration

Maiju-Emilia Huppunen 1 collaboration

Philipp Sergeev 1 collaboration

Muntasir M Majumder 1 collaboration

Juha Lievonen 1 collaboration

Despina Bazou 1 collaboration

Paul Dowling 1 collaboration

Peter O Gorman 1 collaboration

Pekka Anttila 1 collaboration

Raija Silvennoinen 1 collaboration

Nina N Nupponen 1 collaboration

Caroline A Heckman 1 collaboration

Robert Siddaway 1 collaboration

Min Lu 1 collaboration

Thomas Strub 1 collaboration

Rasmus Freter 1 collaboration

Richard Lisle 1 collaboration

Eda Suer 1 collaboration

Benjamin Schuster-Böckler 1 collaboration

Mark Middleton 1 collaboration

Xin Lu 1 collaboration

Irwin Davidson 1 collaboration

Sophie Sarah Steinhaeuser 1 collaboration

Erika Morera 1 collaboration

Zuzana Budkova 1 collaboration

Qiong Wang 1 collaboration

Ottar Rolfsson 1 collaboration

Angela Riedel 1 collaboration

Aileen Krueger 1 collaboration

Bylgja Hilmarsdottir 1 collaboration

Gunhild Mari Maelandsmo 1 collaboration

Bryndis Valdimarsdottir 1 collaboration

Anna Karen Sigurdardottir 1 collaboration

Bjarni Agnar Agnarsson 1 collaboration

Jon Gunnlaugur Jonasson 1 collaboration

Thordur Oskarsson 1 collaboration

Jon Petur Joelsson 1 collaboration

Jennifer Kricker 1 collaboration

Jon Thor Bergthorsson 1 collaboration

Arni Asbjarnarson 1 collaboration

Thorkell Gudjonsson 1 collaboration

Nina Nupponen 1 collaboration

Valerie Fock 1 collaboration

Sigurdur Runar Gudmundsson 1 collaboration

Hilmar Orn Gunnlaugsson 1 collaboration

Jon August Stefansson 1 collaboration

Vivien Ionasz 1 collaboration

Jade Viarigi 1 collaboration

Indridi Einar Reynisson 1 collaboration

Margret Helga Ogmundsdottir 1 collaboration

Eirikur Steingrimsson 1 collaboration

Sarah Picaud 1 collaboration

Anahita Lashgari 1 collaboration