Alain Munafo

Affiliations

Institute of Pharmacometrics, an Affiliate of Merck KGaA, Lausanne, Switzerland.

Publications (13)

Review of Transporter Substrate, Inhibitor, and Inducer Characteristics of Cladribine.

Clinical pharmacokinetics

Avec: Robert Hermann , Peter Krajcsi , Markus Fluck , Annick Seithel-Keuth , Afrim Bytyqi , Andrew Galazka , Alain Munafo

Mitral valve transcatheter edge-to-edge repair with PASCAL Vs MitraClip: A aystematic teview and meta-analysis.

The Journal of invasive cardiology

Avec: Federico Oliveri , Ibtihal Al Amri , José Montero Cabezas , Brian Bingen , Frank Van Der Kley , Fatih Arslan , Roderick Scherptong , Pietro Mazzarotto , Mario Bollati , Antonella Pepe , Lorenzo Tua , Andrea Bongiorno , Alessandro Fasolino , Francesca Romana Gentile , Davide Colombo , Stefano Ghio , Marco Ferlini , Andrea Munafo

The Clinical Pharmacology of Cladribine Tablets for the Treatment of Relapsing Multiple Sclerosis.

Clinical pharmacokinetics

Avec: Robert Hermann , Mats O Karlsson , Ana M Novakovic , Nadia Terranova , Markus Fluck , Alain Munafo

Cladribine as a Potential Object of Nucleoside Transporter-Based Drug Interactions.

Clinical pharmacokinetics

Avec: Robert Hermann , Peter Krajcsi , Markus Fluck , Annick Seithel-Keuth , Afrim Bytyqi , Andrew Galazka , Alain Munafo

Effects of cladribine tablets on heart rate, atrio-ventricular conduction and cardiac repolarization in patients with relapsing multiple sclerosis.

British journal of clinical pharmacology

Avec: Robert Hermann , Jeffrey S Litwin , Lena E Friberg , Fernando Dangond , Alain Munafo

Model-informed assessment of ethnic sensitivity and dosage justification for Asian populations in the global clinical development and use of cladribine tablets.

Clinical and translational science

Avec: Alain Munafo , Nadia Terranova , Dandan Li , Ping Liu , Karthik Venkatakrishnan

Predicting disease activity in patients with multiple sclerosis: An explainable machine-learning approach in the Mavenclad trials.

CPT: pharmacometrics & systems pharmacology

Avec: Sreetama Basu , Alain Munafo , Ali-Frederic Ben-Amor , Sanjeev Roy , Pascal Girard , Nadia Terranova

Designing phase I oncology dose escalation using dose-exposure-toxicity models as a complementary approach to model-based dose-toxicity models.

CPT: pharmacometrics & systems pharmacology

Avec: Kristyn Pantoja , Shankar Lanke , Alain Munafo , Anja Victor , Christina Habermehl , Armin Schueler , Karthik Venkatakrishnan , Pascal Girard , Kosalaram Goteti

Machine Learning Analysis of Individual Tumor Lesions in Four Metastatic Colorectal Cancer Clinical Studies: Linking Tumor Heterogeneity to Overall Survival.

The AAPS journal

Avec: Diego Vera-Yunca , Pascal Girard , Zinnia P Parra-Guillen , Alain Munafo , Iñaki F Trocóniz , Nadia Terranova

Effects of Postponing Treatment in the Second Year of Cladribine Administration: Clinical Trial Simulation Analysis of Absolute Lymphocyte Counts and Relapse Rate in Patients with Relapsing-Remitting Multiple Sclerosis.

Clinical pharmacokinetics

Avec: Nadia Terranova , Christine Hicking , Fernando Dangond , Alain Munafo

Correction to: The Clinical Pharmacology of Cladribine Tablets for the Treatment of Relapsing Multiple Sclerosis.

Clinical pharmacokinetics

Avec: Robert Hermann , Mats O Karlsson , Ana M Novakovic , Nadia Terranova , Markus Fluck , Alain Munafo

Optimization of dose selection using multiple surrogates of toxicity as a continuous variable in phase I cancer trial.

Contemporary clinical trials

Avec: Se Yoon Lee , Alain Munafo , Pascal Girard , Kosalaram Goteti

Semiautomated Pipeline to Quantify Tumor Evolution From Real-World Positron Emission Tomography/Computed Tomography Imaging.

JCO clinical cancer informatics

Avec: Daniel Abler , Perrine Courlet , Matthieu Dietz , Roberto Gatta , Pascal Girard , Alain Munafo , Alexandre Wicky , Mario Jreige , Monia Guidi , Sofiya Latifyan , Rita De Micheli , Chantal Csajka , John O Prior , Olivier Michielin , Nadia Terranova , Michel A Cuendet

Réseau de co-auteurs

Nadia Terranova 7 collaborations

Robert Hermann 5 collaborations

Pascal Girard 5 collaborations

Markus Fluck 4 collaborations

Peter Krajcsi 2 collaborations

Annick Seithel-Keuth 2 collaborations

Afrim Bytyqi 2 collaborations

Andrew Galazka 2 collaborations

Mats O Karlsson 2 collaborations

Ana M Novakovic 2 collaborations

Fernando Dangond 2 collaborations

Karthik Venkatakrishnan 2 collaborations

Kosalaram Goteti 2 collaborations

Federico Oliveri 1 collaboration

Ibtihal Al Amri 1 collaboration

José Montero Cabezas 1 collaboration

Brian Bingen 1 collaboration

Frank Van Der Kley 1 collaboration

Fatih Arslan 1 collaboration

Roderick Scherptong 1 collaboration

Pietro Mazzarotto 1 collaboration

Mario Bollati 1 collaboration

Antonella Pepe 1 collaboration

Lorenzo Tua 1 collaboration

Andrea Bongiorno 1 collaboration

Alessandro Fasolino 1 collaboration

Francesca Romana Gentile 1 collaboration

Davide Colombo 1 collaboration

Stefano Ghio 1 collaboration

Marco Ferlini 1 collaboration

Andrea Munafo 1 collaboration

Jeffrey S Litwin 1 collaboration

Lena E Friberg 1 collaboration

Dandan Li 1 collaboration

Ping Liu 1 collaboration

Sreetama Basu 1 collaboration

Ali-Frederic Ben-Amor 1 collaboration

Sanjeev Roy 1 collaboration

Kristyn Pantoja 1 collaboration

Shankar Lanke 1 collaboration

Anja Victor 1 collaboration

Christina Habermehl 1 collaboration

Armin Schueler 1 collaboration

Diego Vera-Yunca 1 collaboration

Zinnia P Parra-Guillen 1 collaboration

Iñaki F Trocóniz 1 collaboration

Christine Hicking 1 collaboration

Se Yoon Lee 1 collaboration

Daniel Abler 1 collaboration

Perrine Courlet 1 collaboration

Matthieu Dietz 1 collaboration

Roberto Gatta 1 collaboration

Alexandre Wicky 1 collaboration

Mario Jreige 1 collaboration

Monia Guidi 1 collaboration

Sofiya Latifyan 1 collaboration

Rita De Micheli 1 collaboration

Chantal Csajka 1 collaboration

John O Prior 1 collaboration

Olivier Michielin 1 collaboration

Michel A Cuendet 1 collaboration