Adam Skepner

Affiliations

Center for Development of Therapeutics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.

ORCID: 0000-0001-9523-2127

Publications (6)

Optimizing the Cell Painting assay for image-based profiling.

Nature protocols

Avec: Beth A Cimini , Srinivas Niranj Chandrasekaran , Maria Kost-Alimova , Lisa Miller , Amy Goodale , Briana Fritchman , Patrick Byrne , Sakshi Garg , Nasim Jamali , David J Logan , John B Concannon , Charles-Hugues Lardeau , Elizabeth Mouchet , Shantanu Singh , Hamdah Shafqat Abbasi , Peter Aspesi , Justin D Boyd , Tamara Gilbert , David Gnutt , Santosh Hariharan , Desiree Hernandez , Gisela Hormel , Karolina Juhani , Michelle Melanson , Lewis H Mervin , Tiziana Monteverde , James E Pilling , Adam Skepner , Susanne E Swalley , Anita Vrcic , Erin Weisbart , Guy Williams , Shan Yu , Bolek Zapiec , Anne E Carpenter

Three million images and morphological profiles of cells treated with matched chemical and genetic perturbations.

Nature methods

Avec: Srinivas Niranj Chandrasekaran , Beth A Cimini , Amy Goodale , Lisa Miller , Maria Kost-Alimova , Nasim Jamali , John G Doench , Briana Fritchman , Adam Skepner , Michelle Melanson , Alexandr A Kalinin , John Arevalo , Marzieh Haghighi , Juan C Caicedo , Daniel Kuhn , Desiree Hernandez , James Berstler , Hamdah Shafqat-Abbasi , David E Root , Susanne E Swalley , Sakshi Garg , Shantanu Singh , Anne E Carpenter

Molecular basis for substrate recruitment to the PRMT5 methylosome.

Molecular cell

Avec: Kathleen M Mulvaney , Christa Blomquist , Nischal Acharya , Ruitong Li , Matthew J Ranaghan , Meghan O'Keefe , Diego J Rodriguez , Michael J Young , Devishi Kesar , Debjani Pal , Matthew Stokes , Alissa J Nelson , Sidharth S Jain , Annan Yang , Zachary Mullin-Bernstein , Josie Columbus , Fazli K Bozal , Adam Skepner , Donald Raymond , Salvatore LaRussa , David C McKinney , Yelena Freyzon , Yossef Baidi , Dale Porter , Andrew J Aguirre , Alessandra Ianari , Brian McMillan , William R Sellers

nELISA: A high-throughput, high-plex platform enables quantitative profiling of the secretome.

bioRxiv : the preprint server for biology

Avec: Milad Dagher , Grant Ongo , Nathaniel Robichaud , Jinglin Kong , Woojong Rho , Ivan Teahulos , Arya Tavakoli , Samantha Bovaird , Shahem Merjaneh , Andrew Tan , Kiran Edwardson , Christelle Scheepers , Andy Ng , Andy Hajjar , Baly Sow , Michael Vrouvides , Andy Lee , Philippe DeCorwin-Martin , Shafqat Rasool , JiaMin Huang , Yu Han , Timothy Erps , Spencer Coffin , Srinivas Niranj Chandrasekaran , Lisa Miller , Maria Kost-Alimova , Adam Skepner , Shantanu Singh , Anne E Carpenter , Jeffrey Munzar , David Juncker

Discovery of a First-in-Class Inhibitor of the PRMT5-Substrate Adaptor Interaction.

Journal of medicinal chemistry

Avec: David C McKinney , Brian J McMillan , Matthew J Ranaghan , Jamie A Moroco , Merissa Brousseau , Zachary Mullin-Bernstein , Meghan O'Keefe , Patrick McCarren , Michael F Mesleh , Kathleen M Mulvaney , Foxy Robinson , Ritu Singh , Besnik Bajrami , Florence F Wagner , Robert Hilgraf , Martin J Drysdale , Arthur J Campbell , Adam Skepner , David E Timm , Dale Porter , Virendar K Kaushik , William R Sellers , Alessandra Ianari

Identification of Small Molecule Inhibitors of PPM1D Using a Novel Drug Discovery Platform.

bioRxiv : the preprint server for biology

Avec: Wei Jiang , Subrata Shaw , Jason Rush , Nancy Dumont , John Kim , Ritu Singh , Adam Skepner , Carol Khodier , Cerise Raffier , Ni Yan , Cameron Schluter , Xiao Yu , Mateusz Szuchnicki , Murugappan Sathappa , Josephine Kahn , Adam S Sperling , David C McKinney , Alexandra E Gould , Colin W Garvie , Peter G Miller

Réseau de co-auteurs

Srinivas Niranj Chandrasekaran 3 collaborations

Maria Kost-Alimova 3 collaborations

Lisa Miller 3 collaborations

Shantanu Singh 3 collaborations

Anne E Carpenter 3 collaborations

David C McKinney 3 collaborations

Beth A Cimini 2 collaborations

Amy Goodale 2 collaborations

Briana Fritchman 2 collaborations

Sakshi Garg 2 collaborations

Nasim Jamali 2 collaborations

Desiree Hernandez 2 collaborations

Michelle Melanson 2 collaborations

Susanne E Swalley 2 collaborations

Kathleen M Mulvaney 2 collaborations

Matthew J Ranaghan 2 collaborations

Meghan O'Keefe 2 collaborations

Zachary Mullin-Bernstein 2 collaborations

Dale Porter 2 collaborations

Alessandra Ianari 2 collaborations

William R Sellers 2 collaborations

Ritu Singh 2 collaborations

Patrick Byrne 1 collaboration

David J Logan 1 collaboration

John B Concannon 1 collaboration

Charles-Hugues Lardeau 1 collaboration

Elizabeth Mouchet 1 collaboration

Hamdah Shafqat Abbasi 1 collaboration

Peter Aspesi 1 collaboration

Justin D Boyd 1 collaboration

Tamara Gilbert 1 collaboration

David Gnutt 1 collaboration

Santosh Hariharan 1 collaboration

Gisela Hormel 1 collaboration

Karolina Juhani 1 collaboration

Lewis H Mervin 1 collaboration

Tiziana Monteverde 1 collaboration

James E Pilling 1 collaboration

Anita Vrcic 1 collaboration

Erin Weisbart 1 collaboration

Guy Williams 1 collaboration

Shan Yu 1 collaboration

Bolek Zapiec 1 collaboration

John G Doench 1 collaboration

Alexandr A Kalinin 1 collaboration

John Arevalo 1 collaboration

Marzieh Haghighi 1 collaboration

Juan C Caicedo 1 collaboration

Daniel Kuhn 1 collaboration

James Berstler 1 collaboration

Hamdah Shafqat-Abbasi 1 collaboration

David E Root 1 collaboration

Christa Blomquist 1 collaboration

Nischal Acharya 1 collaboration

Ruitong Li 1 collaboration

Diego J Rodriguez 1 collaboration

Michael J Young 1 collaboration

Devishi Kesar 1 collaboration

Debjani Pal 1 collaboration

Matthew Stokes 1 collaboration

Alissa J Nelson 1 collaboration

Sidharth S Jain 1 collaboration

Annan Yang 1 collaboration

Josie Columbus 1 collaboration

Fazli K Bozal 1 collaboration

Donald Raymond 1 collaboration

Salvatore LaRussa 1 collaboration

Yelena Freyzon 1 collaboration

Yossef Baidi 1 collaboration

Andrew J Aguirre 1 collaboration

Brian McMillan 1 collaboration

Milad Dagher 1 collaboration

Grant Ongo 1 collaboration

Nathaniel Robichaud 1 collaboration

Jinglin Kong 1 collaboration

Woojong Rho 1 collaboration

Ivan Teahulos 1 collaboration

Arya Tavakoli 1 collaboration

Samantha Bovaird 1 collaboration

Shahem Merjaneh 1 collaboration

Andrew Tan 1 collaboration

Kiran Edwardson 1 collaboration

Christelle Scheepers 1 collaboration

Andy Ng 1 collaboration

Andy Hajjar 1 collaboration

Baly Sow 1 collaboration

Michael Vrouvides 1 collaboration

Andy Lee 1 collaboration

Philippe DeCorwin-Martin 1 collaboration

Shafqat Rasool 1 collaboration

JiaMin Huang 1 collaboration

Yu Han 1 collaboration

Timothy Erps 1 collaboration

Spencer Coffin 1 collaboration

Jeffrey Munzar 1 collaboration

David Juncker 1 collaboration

Brian J McMillan 1 collaboration

Jamie A Moroco 1 collaboration

Merissa Brousseau 1 collaboration

Patrick McCarren 1 collaboration

Michael F Mesleh 1 collaboration

Foxy Robinson 1 collaboration

Besnik Bajrami 1 collaboration

Florence F Wagner 1 collaboration

Robert Hilgraf 1 collaboration

Martin J Drysdale 1 collaboration

Arthur J Campbell 1 collaboration

David E Timm 1 collaboration

Virendar K Kaushik 1 collaboration

Wei Jiang 1 collaboration

Subrata Shaw 1 collaboration

Jason Rush 1 collaboration

Nancy Dumont 1 collaboration

John Kim 1 collaboration

Carol Khodier 1 collaboration

Cerise Raffier 1 collaboration

Ni Yan 1 collaboration

Cameron Schluter 1 collaboration

Xiao Yu 1 collaboration

Mateusz Szuchnicki 1 collaboration

Murugappan Sathappa 1 collaboration

Josephine Kahn 1 collaboration

Adam S Sperling 1 collaboration

Alexandra E Gould 1 collaboration

Colin W Garvie 1 collaboration

Peter G Miller 1 collaboration