Wolfgang Fischle

Affiliations

Biological and Environmental Science and Engineering Division, King Abdullah University of Science and Technology Thuwal 23955 Saudi Arabia wolfgang.fischle@kaust.edu.sa.
Laboratory of Chromatin Biochemistry, Max Planck Institute for Biophysical Chemistry 37077 Göttingen Germany.

Publications (14)

Examining histone modification crosstalk using immobilized libraries established from ligation-ready nucleosomes.

Chemical science

Avec: Diego Aparicio Pelaz , Zhadyra Yerkesh , Sören Kirchgäßner , Henriette Mahler , Vladlena Kharchenko , Dulat Azhibek , Mariusz Jaremko , Henning D Mootz , Łukasz Jaremko , Dirk Schwarzer ,

Unconventional metabolites in chromatin regulation.

Bioscience reports

Avec: Liubov Gapa , Huda Alfardus ,

Multimodal interactions drive chromatin phase separation and compaction.

Proceedings of the National Academy of Sciences of the United States of America

Avec: Tina Ukmar-Godec , Maria-Sol Cima-Omori , Zhadyra Yerkesh , Karthik Eswara , Taekyung Yu , Reshma Ramesh , Gwladys Riviere , Alain Ibanez de Opakua , Markus Zweckstetter

A new approach for quantifying epigenetic landscapes.

The Journal of biological chemistry

Avec:

CRISPR-broad: combined design of multi-targeting gRNAs and broad, multiplex target finding.

Scientific reports

Avec: Alaguraj Veluchamy , Kaian Teles ,

Molecular basis of hUHRF1 allosteric activation for synergistic histone modification binding by PI5P.

Science advances

Avec: Papita Mandal , Karthik Eswara , Zhadyra Yerkesh , Vladlena Kharchenko , Levani Zandarashvili , Kacper Szczepski , Dalila Bensaddek , Łukasz Jaremko , Ben E Black ,

PfAP2-MRP DNA-binding protein is a master regulator of parasite pathogenesis during malaria parasite blood stages.

bioRxiv : the preprint server for biology

Avec: Amit Kumar Subudhi , Judith L Green , Rohit Satyam , Todd Lenz , Rahul P Salunke , Muhammad Shuaib , Ioannis Isaioglou , Steven Abel , Mohit Gupta , Luke Esau , Tobias Mourier , Raushan Nugmanova , Sara Mfarrej , Rupali Sivapurkar , Zenaida Stead , Fathia Ben Rached , Yogesh Otswal , Rachid Sougrat , Ashraf Dada , Abdullah Fuaad Kadamany , Jasmeen Merzaban , Ellen Knuepfer , David J P Ferguson , Ishaan Gupta , Karine G Le Roch , Anthony A Holder , Arnab Pain

Analysis of protein-DNA interactions in chromatin by UV induced cross-linking and mass spectrometry.

Nature communications

Avec: Alexandra Stützer , Luisa M Welp , Monika Raabe , Timo Sachsenberg , Christin Kappert , Alexander Wulf , Andy M Lau , Stefan-Sebastian David , Aleksandar Chernev , Katharina Kramer , Argyris Politis , Oliver Kohlbacher , Henning Urlaub

Elevated NSD3 histone methylation activity drives squamous cell lung cancer.

Nature

Avec: Gang Yuan , Natasha M Flores , Simone Hausmann , Shane M Lofgren , Vladlena Kharchenko , Maria Angulo-Ibanez , Deepanwita Sengupta , Xiaoyin Lu , Iwona Czaban , Dulat Azhibek , Silvestre Vicent , Mariusz Jaremko , Bingliang Fang , Ignacio I Wistuba , Katrin F Chua , Jack A Roth , John D Minna , Ning-Yi Shao , Łukasz Jaremko , Pawel K Mazur , Or Gozani

Nuclear localization and phosphorylation modulate pathological effects of alpha-synuclein.

Human molecular genetics

Avec: Raquel Pinho , Isabel Paiva , Kristina Gotovac Jercic , Luis Fonseca-Ornelas , Ellen Gerhardt , Christiane Fahlbusch , Paula Garcia-Esparcia , Cemil Kerimoglu , Maria A S Pavlou , Anna Villar-Piqué , Éva Szego , Tomás Lopes da Fonseca , Francesca Odoardi , Szabolcs Soeroes , Ana Cristina Rego , Jens C Schwamborn , Thomas Meyer , Sebastian Kügler , Isidre Ferrer , Johannes Attems , André Fischer , Stefan Becker , Markus Zweckstetter , Fran Borovecki , Tiago F Outeiro

Alternative splicing and allosteric regulation modulate the chromatin binding of UHRF1.

Nucleic acids research

Avec: Maria Tauber , Sarah Kreuz , Alexander Lemak , Papita Mandal , Zhadyra Yerkesh , Alaguraj Veluchamy , Bothayna Al-Gashgari , Abrar Aljahani , Lorena V Cortés-Medina , Dulat Azhibek , Lixin Fan , Michelle S Ong , Shili Duan , Scott Houliston , Cheryl H Arrowsmith ,

NSD2 dimethylation at H3K36 promotes lung adenocarcinoma pathogenesis.

Molecular cell

Avec: Deepanwita Sengupta , Liyong Zeng , Yumei Li , Simone Hausmann , Debopam Ghosh , Gang Yuan , Thuyen N Nguyen , Ruitu Lyu , Marcello Caporicci , Ana Morales Benitez , Garry L Coles , Vladlena Kharchenko , Iwona Czaban , Dulat Azhibek , Mariusz Jaremko , Ignacio I Wistuba , Julien Sage , Łukasz Jaremko , Wei Li , Pawel K Mazur , Or Gozani

Modulation of the microhomology-mediated end joining pathway suppresses large deletions and enhances homology-directed repair following CRISPR-Cas9-induced DNA breaks.

BMC biology

Avec: Baolei Yuan , Chongwei Bi , Yeteng Tian , Jincheng Wang , Yiqing Jin , Khaled Alsayegh , Muhammad Tehseen , Gang Yi , Xuan Zhou , Yanjiao Shao , Fernanda Vargas Romero , Juan Carlos Izpisua Belmonte , Samir Hamdan , Yanyi Huang , Mo Li

DNA-binding protein PfAP2-P regulates parasite pathogenesis during malaria parasite blood stages.

Nature microbiology

Avec: Amit Kumar Subudhi , Judith L Green , Rohit Satyam , Rahul P Salunke , Todd Lenz , Muhammad Shuaib , Ioannis Isaioglou , Steven Abel , Mohit Gupta , Luke Esau , Tobias Mourier , Raushan Nugmanova , Sara Mfarrej , Rupali Shivapurkar , Zenaida Stead , Fathia Ben Rached , Yogesh Ostwal , Rachid Sougrat , Ashraf Dada , Abdullah Fuaad Kadamany , Jasmeen Merzaban , Ellen Knuepfer , David J P Ferguson , Ishaan Gupta , Karine G Le Roch , Anthony A Holder , Arnab Pain

Réseau de co-auteurs

Zhadyra Yerkesh 4 collaborations

Vladlena Kharchenko 4 collaborations

Dulat Azhibek 4 collaborations

Łukasz Jaremko 4 collaborations

Mariusz Jaremko 3 collaborations

Karthik Eswara 2 collaborations

Markus Zweckstetter 2 collaborations

Alaguraj Veluchamy 2 collaborations

Papita Mandal 2 collaborations

Amit Kumar Subudhi 2 collaborations

Judith L Green 2 collaborations

Rohit Satyam 2 collaborations

Todd Lenz 2 collaborations

Rahul P Salunke 2 collaborations

Muhammad Shuaib 2 collaborations

Ioannis Isaioglou 2 collaborations

Steven Abel 2 collaborations

Mohit Gupta 2 collaborations

Luke Esau 2 collaborations

Tobias Mourier 2 collaborations

Raushan Nugmanova 2 collaborations

Sara Mfarrej 2 collaborations

Zenaida Stead 2 collaborations

Fathia Ben Rached 2 collaborations

Rachid Sougrat 2 collaborations

Ashraf Dada 2 collaborations

Abdullah Fuaad Kadamany 2 collaborations

Jasmeen Merzaban 2 collaborations

Ellen Knuepfer 2 collaborations

David J P Ferguson 2 collaborations

Ishaan Gupta 2 collaborations

Karine G Le Roch 2 collaborations

Anthony A Holder 2 collaborations

Arnab Pain 2 collaborations

Gang Yuan 2 collaborations

Simone Hausmann 2 collaborations

Deepanwita Sengupta 2 collaborations

Iwona Czaban 2 collaborations

Ignacio I Wistuba 2 collaborations

Pawel K Mazur 2 collaborations

Or Gozani 2 collaborations

Diego Aparicio Pelaz 1 collaboration

Sören Kirchgäßner 1 collaboration

Henriette Mahler 1 collaboration

Henning D Mootz 1 collaboration

Dirk Schwarzer 1 collaboration

Liubov Gapa 1 collaboration

Huda Alfardus 1 collaboration

Tina Ukmar-Godec 1 collaboration

Maria-Sol Cima-Omori 1 collaboration

Taekyung Yu 1 collaboration

Reshma Ramesh 1 collaboration

Gwladys Riviere 1 collaboration

Alain Ibanez de Opakua 1 collaboration

Kaian Teles 1 collaboration

Levani Zandarashvili 1 collaboration

Kacper Szczepski 1 collaboration

Dalila Bensaddek 1 collaboration

Ben E Black 1 collaboration

Rupali Sivapurkar 1 collaboration

Yogesh Otswal 1 collaboration

Alexandra Stützer 1 collaboration

Luisa M Welp 1 collaboration

Monika Raabe 1 collaboration

Timo Sachsenberg 1 collaboration

Christin Kappert 1 collaboration

Alexander Wulf 1 collaboration

Andy M Lau 1 collaboration

Stefan-Sebastian David 1 collaboration

Aleksandar Chernev 1 collaboration

Katharina Kramer 1 collaboration

Argyris Politis 1 collaboration

Oliver Kohlbacher 1 collaboration

Henning Urlaub 1 collaboration

Natasha M Flores 1 collaboration

Shane M Lofgren 1 collaboration

Maria Angulo-Ibanez 1 collaboration

Xiaoyin Lu 1 collaboration

Silvestre Vicent 1 collaboration

Bingliang Fang 1 collaboration

Katrin F Chua 1 collaboration

Jack A Roth 1 collaboration

John D Minna 1 collaboration

Ning-Yi Shao 1 collaboration

Raquel Pinho 1 collaboration

Isabel Paiva 1 collaboration

Kristina Gotovac Jercic 1 collaboration

Luis Fonseca-Ornelas 1 collaboration

Ellen Gerhardt 1 collaboration

Christiane Fahlbusch 1 collaboration

Paula Garcia-Esparcia 1 collaboration

Cemil Kerimoglu 1 collaboration

Maria A S Pavlou 1 collaboration

Anna Villar-Piqué 1 collaboration

Éva Szego 1 collaboration

Tomás Lopes da Fonseca 1 collaboration

Francesca Odoardi 1 collaboration

Szabolcs Soeroes 1 collaboration

Ana Cristina Rego 1 collaboration

Jens C Schwamborn 1 collaboration

Thomas Meyer 1 collaboration

Sebastian Kügler 1 collaboration

Isidre Ferrer 1 collaboration

Johannes Attems 1 collaboration

André Fischer 1 collaboration

Stefan Becker 1 collaboration

Fran Borovecki 1 collaboration

Tiago F Outeiro 1 collaboration

Maria Tauber 1 collaboration

Sarah Kreuz 1 collaboration

Alexander Lemak 1 collaboration

Bothayna Al-Gashgari 1 collaboration

Abrar Aljahani 1 collaboration

Lorena V Cortés-Medina 1 collaboration

Lixin Fan 1 collaboration

Michelle S Ong 1 collaboration

Shili Duan 1 collaboration

Scott Houliston 1 collaboration

Cheryl H Arrowsmith 1 collaboration

Liyong Zeng 1 collaboration

Yumei Li 1 collaboration

Debopam Ghosh 1 collaboration

Thuyen N Nguyen 1 collaboration

Ruitu Lyu 1 collaboration

Marcello Caporicci 1 collaboration

Ana Morales Benitez 1 collaboration

Garry L Coles 1 collaboration

Julien Sage 1 collaboration

Wei Li 1 collaboration

Baolei Yuan 1 collaboration

Chongwei Bi 1 collaboration

Yeteng Tian 1 collaboration

Jincheng Wang 1 collaboration

Yiqing Jin 1 collaboration

Khaled Alsayegh 1 collaboration

Muhammad Tehseen 1 collaboration

Gang Yi 1 collaboration

Xuan Zhou 1 collaboration

Yanjiao Shao 1 collaboration

Fernanda Vargas Romero 1 collaboration

Juan Carlos Izpisua Belmonte 1 collaboration

Samir Hamdan 1 collaboration

Yanyi Huang 1 collaboration

Mo Li 1 collaboration

Rupali Shivapurkar 1 collaboration

Yogesh Ostwal 1 collaboration