Vassilios Bavetsias

Affiliations

Cancer Research UK Cancer Therapeutics Unit, The Institute of Cancer Research, London, United Kingdom.

Publications (5)

Metabolism of the dual FLT-3/Aurora kinase inhibitor CCT241736 in preclinical and human in vitro models: Implication for the choice of toxicology species.

European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences

Avec: Francesca L Wood , Sam Shepherd , Angela Hayes , Manjuan Liu , Katia Grira , Yi Mok , Butrus Atrash , Amir Faisal , Spiros Linardopoulos , Julian Blagg , Florence I Raynaud

Design, Synthesis and Characterization of Covalent KDM5 Inhibitors.

Angewandte Chemie (International ed. in English)

Avec: Saleta Vazquez-Rodriguez , Miranda Wright , Catherine M Rogers , Adam P Cribbs , Srikannathasan Velupillai , Martin Philpott , Henry Lee , James E Dunford , Kilian V M Huber , Matthew B Robers , James D Vasta , Marie-Laetitia Thezenas , Sarah Bonham , Benedikt Kessler , James Bennett , Oleg Fedorov , Florence Raynaud , Adam Donovan , Julian Blagg , Udo Oppermann , Chas Bountra , Akane Kawamura , Paul E Brennan

CCT245718, a dual FLT3/Aurora A inhibitor overcomes D835Y-mediated resistance to FLT3 inhibitors in acute myeloid leukaemia cells.

British journal of cancer

Avec: Muhammad Usama Tariq , Muhammad Furqan , Hira Parveen , Rahim Ullah , Muhammad Muddassar , Rahman Shah Zaib Saleem , Spiros Linardopoulos , Amir Faisal

Quizartinib-resistant FLT3-ITD acute myeloid leukemia cells are sensitive to the FLT3-Aurora kinase inhibitor CCT241736.

Blood advances

Avec: Andrew S Moore , Amir Faisal , Grace W Y Mak , Farideh Miraki-Moud , Melanie Valenti , Gary Box , Albert Hallsworth , Alexis de Haven Brandon , Cristina P R Xavier , Randal Stronge , Andrew D J Pearson , Julian Blagg , Florence I Raynaud , Rajesh Chopra , Suzanne A Eccles , David C Taussig , Spiros Linardopoulos

C8-substituted pyrido[3,4-d]pyrimidin-4(3H)-ones: Studies towards the identification of potent, cell penetrant Jumonji C domain containing histone lysine demethylase 4 subfamily (KDM4) inhibitors, compound profiling in cell-based target engagement assays.

European journal of medicinal chemistry

Avec: Yann-Vaï Le Bihan , Rachel M Lanigan , Butrus Atrash , Mark G McLaughlin , Srikannathasan Velupillai , Andrew G Malcolm , Katherine S England , Gian Filippo Ruda , N Yi Mok , Anthony Tumber , Kathy Tomlin , Harry Saville , Erald Shehu , Craig McAndrew , LeAnne Carmichael , James M Bennett , Fiona Jeganathan , Paul Eve , Adam Donovan , Angela Hayes , Francesca Wood , Florence I Raynaud , Oleg Fedorov , Paul E Brennan , Rosemary Burke , Rob L M van Montfort , Olivia W Rossanese , Julian Blagg ,

Réseau de co-auteurs

Julian Blagg 4 collaborations

Amir Faisal 3 collaborations

Spiros Linardopoulos 3 collaborations

Florence I Raynaud 3 collaborations

Angela Hayes 2 collaborations

Butrus Atrash 2 collaborations

Srikannathasan Velupillai 2 collaborations

Oleg Fedorov 2 collaborations

Adam Donovan 2 collaborations

Paul E Brennan 2 collaborations

Francesca L Wood 1 collaboration

Sam Shepherd 1 collaboration

Manjuan Liu 1 collaboration

Katia Grira 1 collaboration

Yi Mok 1 collaboration

Saleta Vazquez-Rodriguez 1 collaboration

Miranda Wright 1 collaboration

Catherine M Rogers 1 collaboration

Adam P Cribbs 1 collaboration

Martin Philpott 1 collaboration

Henry Lee 1 collaboration

James E Dunford 1 collaboration

Kilian V M Huber 1 collaboration

Matthew B Robers 1 collaboration

James D Vasta 1 collaboration

Marie-Laetitia Thezenas 1 collaboration

Sarah Bonham 1 collaboration

Benedikt Kessler 1 collaboration

James Bennett 1 collaboration

Florence Raynaud 1 collaboration

Udo Oppermann 1 collaboration

Chas Bountra 1 collaboration

Akane Kawamura 1 collaboration

Muhammad Usama Tariq 1 collaboration

Muhammad Furqan 1 collaboration

Hira Parveen 1 collaboration

Rahim Ullah 1 collaboration

Muhammad Muddassar 1 collaboration

Rahman Shah Zaib Saleem 1 collaboration

Andrew S Moore 1 collaboration

Grace W Y Mak 1 collaboration

Farideh Miraki-Moud 1 collaboration

Melanie Valenti 1 collaboration

Gary Box 1 collaboration

Albert Hallsworth 1 collaboration

Alexis de Haven Brandon 1 collaboration

Cristina P R Xavier 1 collaboration

Randal Stronge 1 collaboration

Andrew D J Pearson 1 collaboration

Rajesh Chopra 1 collaboration

Suzanne A Eccles 1 collaboration

David C Taussig 1 collaboration

Yann-Vaï Le Bihan 1 collaboration

Rachel M Lanigan 1 collaboration

Mark G McLaughlin 1 collaboration

Andrew G Malcolm 1 collaboration

Katherine S England 1 collaboration

Gian Filippo Ruda 1 collaboration

N Yi Mok 1 collaboration

Anthony Tumber 1 collaboration

Kathy Tomlin 1 collaboration

Harry Saville 1 collaboration

Erald Shehu 1 collaboration

Craig McAndrew 1 collaboration

LeAnne Carmichael 1 collaboration

James M Bennett 1 collaboration

Fiona Jeganathan 1 collaboration

Paul Eve 1 collaboration

Francesca Wood 1 collaboration

Rosemary Burke 1 collaboration

Rob L M van Montfort 1 collaboration

Olivia W Rossanese 1 collaboration