V P Hytönen

Affiliations

Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
Fimlab Laboratories, Tampere, Finland.

Publications (38)

Biochemical and structural characterisation of a protozoan beta-carbonic anhydrase from

Journal of enzyme inhibition and medicinal chemistry

Avec: Linda J Urbański , Anna Di Fiore , Latifeh Azizi , Vesa P Hytönen , Marianne Kuuslahti , Martina Buonanno , Simona M Monti , Andrea Angeli , Reza Zolfaghari Emameh , Claudiu T Supuran , Giuseppina De Simone , Seppo Parkkila

Rotavirus Inner Capsid VP6 Acts as an Adjuvant in Formulations with Particulate Antigens Only.

Vaccines

Avec: Suvi Heinimäki , Kirsi Tamminen , Vesa P Hytönen , Maria Malm , Vesna Blazevic

(Strept)avidin as a template for ligands other than biotin: An overview.

Methods in enzymology

Avec: Vesa P Hytönen

Cell Adhesion by Integrins.

Physiological reviews

Avec: Michael Bachmann , Sampo Kukkurainen , Vesa P Hytönen , Bernhard Wehrle-Haller

Molecular features of steroid-binding antidins and their use for assaying serum progesterone.

PloS one

Avec: Nitin Agrawal , Soili I Lehtonen , Meri Uusi-Mäkelä , Purvi Jain , Sari Viitala , Juha A E Määttä , Niklas Kähkönen , Latifeh Azizi , Tiina A Riihimäki , Markku S Kulomaa , Mark S Johnson , Vesa P Hytönen , Tomi T Airenne

Activation of the β-carbonic anhydrase from the protozoan pathogen

Journal of enzyme inhibition and medicinal chemistry

Avec: Andrea Angeli , Linda J Urbański , Vesa P Hytönen , Seppo Parkkila , Claudiu T Supuran

Cancer associated talin point mutations disorganise cell adhesion and migration.

Scientific reports

Avec: Latifeh Azizi , Alana R Cowell , Vasyl V Mykuliak , Benjamin T Goult , Paula Turkki , Vesa P Hytönen

Extrusion-Based Bioprinting of Multilayered Nanocellulose Constructs for Cell Cultivation Using

ACS omega

Avec: Anum Rasheed , Latifeh Azizi , Paula Turkki , Marika Janka , Vesa P Hytönen , Sampo Tuukkanen

Modular vaccine platform based on the norovirus-like particle.

Journal of nanobiotechnology

Avec: Vili Lampinen , Suvi Heinimäki , Olli H Laitinen , Marko Pesu , Minna M Hankaniemi , Vesna Blazevic , Vesa P Hytönen

The production and biochemical characterization of α-carbonic anhydrase from Lactobacillus rhamnosus GG.

Applied microbiology and biotechnology

Avec: Linda J Urbański , Silvia Bua , Andrea Angeli , Reza Zolfaghari Emameh , Harlan R Barker , Marianne Kuuslahti , Vesa P Hytönen , Seppo Parkkila , Claudiu T Supuran

DNA-origami-directed virus capsid polymorphism.

Nature nanotechnology

Avec: Iris Seitz , Sharon Saarinen , Esa-Pekka Kumpula , Donna McNeale , Eduardo Anaya-Plaza , Vili Lampinen , Vesa P Hytönen , Frank Sainsbury , Jeroen J L M Cornelissen , Veikko Linko , Juha T Huiskonen , Mauri A Kostiainen

SpyTag/SpyCatcher display of influenza M2e peptide on norovirus-like particle provides stronger immunization than direct genetic fusion.

Frontiers in cellular and infection microbiology

Avec: Vili Lampinen , Stina Gröhn , Saana Soppela , Vesna Blazevic , Vesa P Hytönen , Minna M Hankaniemi

A hexavalent Coxsackievirus B vaccine is highly immunogenic and has a strong protective capacity in mice and nonhuman primates.

Science advances

Avec: V M Stone , M M Hankaniemi , O H Laitinen , A B Sioofy-Khojine , A Lin , I M Diaz Lozano , M A Mazur , V Marjomäki , K Loré , H Hyöty , M Flodström-Tullberg

Combination of three virus-derived nanoparticles as a vaccine against enteric pathogens; enterovirus, norovirus and rotavirus.

Vaccine

Avec: Suvi Heinimäki , Minna M Hankaniemi , Amir-Babak Sioofy-Khojine , Olli H Laitinen , Heikki Hyöty , Vesa P Hytönen , Timo Vesikari , Vesna Blazevic

Intelectin 3 is dispensable for resistance against a mycobacterial infection in zebrafish (Danio rerio).

Scientific reports

Avec: Markus J T Ojanen , Meri I E Uusi-Mäkelä , Sanna-Kaisa E Harjula , Anni K Saralahti , Kaisa E Oksanen , Niklas Kähkönen , Juha A E Määttä , Vesa P Hytönen , Marko Pesu , Mika Rämet

The F1 loop of the talin head domain acts as a gatekeeper in integrin activation and clustering.

Journal of cell science

Avec: Sampo Kukkurainen , Latifeh Azizi , Pingfeng Zhang , Marie-Claude Jacquier , Mo Baikoghli , Magdaléna von Essen , Anne Tuukkanen , Mikko Laitaoja , Xiaonan Liu , Rolle Rahikainen , Adam Orłowski , Janne Jänis , Juha A E Määttä , Markku Varjosalo , Ilpo Vattulainen , Tomasz Róg , Dmitri Svergun , R Holland Cheng , Jinhua Wu , Vesa P Hytönen , Bernhard Wehrle-Haller

Correction: Saarinen, N.V.V., et al. Multiplexed High-Throughput Serological Assay for Human Enteroviruses.

Microorganisms

Avec: Niila V V Saarinen , Jussi Lehtonen , Riitta Veijola , Johanna Lempainen , Mikael Knip , Heikki Hyöty , Olli H Laitinen , Vesa P Hytönen

Structural and functional analysis of LIM domain-dependent recruitment of paxillin to αvβ3 integrin-positive focal adhesions.

Communications biology

Avec: Marta Ripamonti , Nicolas Liaudet , Latifeh Azizi , Daniel Bouvard , Vesa P Hytönen , Bernhard Wehrle-Haller

Crystal structure of the FERM-folded talin head reveals the determinants for integrin binding.

Proceedings of the National Academy of Sciences of the United States of America

Avec: Pingfeng Zhang , Latifeh Azizi , Sampo Kukkurainen , Tong Gao , Mo Baikoghli , Marie-Claude Jacquier , Yijuan Sun , Juha A E Määttä , R Holland Cheng , Bernhard Wehrle-Haller , Vesa P Hytönen , Jinhua Wu

Biochemical and Biophysical Characterization of Carbonic Anhydrase VI from Human Milk and Saliva.

The protein journal

Avec: Alma Yrjänäinen , Maarit S Patrikainen , Latifeh Azizi , Martti E E Tolvanen , Mikko Laitaoja , Janne Jänis , Vesa P Hytönen , Alessio Nocentini , Claudiu T Supuran , Seppo Parkkila

Structural mechanism for inhibition of PP2A-B56α and oncogenicity by CIP2A.

Nature communications

Avec: Karolina Pavic , Nikhil Gupta , Judit Domènech Omella , Rita Derua , Anna Aakula , Riikka Huhtaniemi , Juha A Määttä , Nico Höfflin , Juha Okkeri , Zhizhi Wang , Otto Kauko , Roosa Varjus , Henrik Honkanen , Daniel Abankwa , Maja Köhn , Vesa P Hytönen , Wenqing Xu , Jakob Nilsson , Rebecca Page , Veerle Janssens , Alexander Leitner , Jukka Westermarck

Visible light-induced specific protein reaction delineates early stages of cell adhesion.

bioRxiv : the preprint server for biology

Avec: Rolle Rahikainen , Susan K Vester , Paula Turkki , Chasity P Janosko , Alexander Deiters , Vesa P Hytönen , Mark Howarth

Experimental VLP vaccine displaying a furin antigen elicits production of autoantibodies and is well tolerated in mice.

Nanoscale advances

Avec: Vili Lampinen , Markus J T Ojanen , Fernanda Muñoz Caro , Stina Gröhn , Minna M Hankaniemi , Marko Pesu , Vesa P Hytönen

Inhibition of the newly discovered β‑carbonic anhydrase from the protozoan pathogen Trichomonas vaginalis with inorganic anions and small molecules.

Journal of inorganic biochemistry

Avec: Linda J Urbański , Andrea Angeli , Vesa P Hytönen , Anna Di Fiore , Seppo Parkkila , Giuseppina De Simone , Claudiu T Supuran

Competitive binding assay for biotin and biotin derivatives, based on avidin and biotin-4-fluorescein.

Methods in enzymology

Avec: Elke Oberbichler , Maria Wiesauer , Eva Schlögl , Jessica Stangl , Felix Faschinger , Günther Knör , Hermann J Gruber , Vesa P Hytönen

A comparative study of the effect of UV and formalin inactivation on the stability and immunogenicity of a Coxsackievirus B1 vaccine.

Vaccine

Avec: Minna M Hankaniemi , Virginia M Stone , Amir-Babak Sioofy-Khojine , Suvi Heinimäki , Varpu Marjomäki , Heikki Hyöty , Vesna Blazevic , Olli H Laitinen , Malin Flodström-Tullberg , Vesa P Hytönen

Formalin treatment increases the stability and immunogenicity of coxsackievirus B1 VLP vaccine.

Antiviral research

Avec: Minna M Hankaniemi , Virginia M Stone , Tanja Andrejeff , Suvi Heinimäki , Amir-Babak Sioofy-Khojine , Varpu Marjomäki , Heikki Hyöty , Vesna Blazevic , Malin Flodström-Tullberg , Vesa P Hytönen , Olli H Laitinen

Talin-mediated force transmission and talin rod domain unfolding independently regulate adhesion signaling.

Journal of cell science

Avec: Rolle Rahikainen , Tiina Öhman , Paula Turkki , Markku Varjosalo , Vesa P Hytönen

Mechanical Unfolding of Proteins-A Comparative Nonequilibrium Molecular Dynamics Study.

Biophysical journal

Avec: Vasyl V Mykuliak , Mateusz Sikora , Jonathan J Booth , Marek Cieplak , Dmitrii V Shalashilin , Vesa P Hytönen

Surface Modification of Bioactive Glass Promotes Cell Attachment and Spreading.

ACS omega

Avec: Latifeh Azizi , Paula Turkki , Ngoc Huynh , Jonathan M Massera , Vesa P Hytönen

Biochemical and structural characterization of beta-carbonic anhydrase from the parasite Trichomonas vaginalis.

Journal of molecular medicine (Berlin, Germany)

Avec: Linda J Urbański , Andrea Angeli , Vasyl V Mykuliak , Latifeh Azizi , Marianne Kuuslahti , Vesa P Hytönen , Claudiu T Supuran , Seppo Parkkila

Molecular dynamics simulations reveal how vinculin refolds partially unfolded talin rod helices to stabilize them against mechanical force.

PLoS computational biology

Avec: Vasyl V Mykuliak , Rolle Rahikainen , Neil J Ball , Giovanni Bussi , Benjamin T Goult , Vesa P Hytönen

The mechanical cell - the role of force dependencies in synchronising protein interaction networks.

Journal of cell science

Avec: Benjamin T Goult , Magdaléna von Essen , Vesa P Hytönen

Assessment of Enterovirus Antibodies during Early Childhood Using a Multiplex Immunoassay.

Microbiology spectrum

Avec: N V V Jouppila , J Lehtonen , E Seppälä , L Puustinen , S Oikarinen , O H Laitinen , M Knip , H Hyöty ,

Tensin-2 interactomics reveals interaction with GAPDH and a phosphorylation-mediated regulatory role in glycolysis.

Scientific reports

Avec: Paula Turkki , Iftekhar Chowdhury , Tiina Öhman , Latifeh Azizi , Markku Varjosalo , Vesa P Hytönen

Modern Tools for Rapid Diagnostics of Antimicrobial Resistance.

Frontiers in cellular and infection microbiology

Avec: Antti Vasala , Vesa P Hytönen , Olli H Laitinen

Antibody Responses against Enterovirus Proteases are Potential Markers for an Acute Infection.

Viruses

Avec: Niila V V Saarinen , Virginia M Stone , Minna M Hankaniemi , Magdalena A Mazur , Tytti Vuorinen , Malin Flodström-Tullberg , Heikki Hyöty , Vesa P Hytönen , Olli H Laitinen

Structural Insight into CVB3-VLP Non-Adjuvanted Vaccine.

Microorganisms

Avec: Minna M Hankaniemi , Mo A Baikoghli , Virginia M Stone , Li Xing , Outi Väätäinen , Saana Soppela , Amirbabak Sioofy-Khojine , Niila V V Saarinen , Tingwei Ou , Brandon Anson , Heikki Hyöty , Varpu Marjomäki , Malin Flodström-Tullberg , R Holland Cheng , Vesa P Hytönen , Olli H Laitinen

Réseau de co-auteurs

Vesa P Hytönen 36 collaborations

Latifeh Azizi 11 collaborations

Olli H Laitinen 8 collaborations

Minna M Hankaniemi 8 collaborations

Claudiu T Supuran 6 collaborations

Seppo Parkkila 6 collaborations

Vesna Blazevic 6 collaborations

Paula Turkki 6 collaborations

Heikki Hyöty 6 collaborations

Linda J Urbański 5 collaborations

Andrea Angeli 5 collaborations

Suvi Heinimäki 5 collaborations

Bernhard Wehrle-Haller 4 collaborations

Juha A E Määttä 4 collaborations

Vasyl V Mykuliak 4 collaborations

Vili Lampinen 4 collaborations

Rolle Rahikainen 4 collaborations

Virginia M Stone 4 collaborations

Malin Flodström-Tullberg 4 collaborations

Marianne Kuuslahti 3 collaborations

Sampo Kukkurainen 3 collaborations

Benjamin T Goult 3 collaborations

Marko Pesu 3 collaborations

Amir-Babak Sioofy-Khojine 3 collaborations

Markku Varjosalo 3 collaborations

R Holland Cheng 3 collaborations

Niila V V Saarinen 3 collaborations

Varpu Marjomäki 3 collaborations

Anna Di Fiore 2 collaborations

Reza Zolfaghari Emameh 2 collaborations

Giuseppina De Simone 2 collaborations

Niklas Kähkönen 2 collaborations

Stina Gröhn 2 collaborations

Saana Soppela 2 collaborations

O H Laitinen 2 collaborations

H Hyöty 2 collaborations

Markus J T Ojanen 2 collaborations

Pingfeng Zhang 2 collaborations

Marie-Claude Jacquier 2 collaborations

Mo Baikoghli 2 collaborations

Magdaléna von Essen 2 collaborations

Mikko Laitaoja 2 collaborations

Janne Jänis 2 collaborations

Jinhua Wu 2 collaborations

Tiina Öhman 2 collaborations

Martina Buonanno 1 collaboration

Simona M Monti 1 collaboration

Kirsi Tamminen 1 collaboration

Maria Malm 1 collaboration

Michael Bachmann 1 collaboration

Nitin Agrawal 1 collaboration

Soili I Lehtonen 1 collaboration

Meri Uusi-Mäkelä 1 collaboration

Purvi Jain 1 collaboration

Sari Viitala 1 collaboration

Tiina A Riihimäki 1 collaboration

Markku S Kulomaa 1 collaboration

Mark S Johnson 1 collaboration

Tomi T Airenne 1 collaboration

Alana R Cowell 1 collaboration

Anum Rasheed 1 collaboration

Marika Janka 1 collaboration

Sampo Tuukkanen 1 collaboration

Silvia Bua 1 collaboration

Harlan R Barker 1 collaboration

Iris Seitz 1 collaboration

Sharon Saarinen 1 collaboration

Esa-Pekka Kumpula 1 collaboration

Donna McNeale 1 collaboration

Eduardo Anaya-Plaza 1 collaboration

Frank Sainsbury 1 collaboration

Jeroen J L M Cornelissen 1 collaboration

Veikko Linko 1 collaboration

Juha T Huiskonen 1 collaboration

Mauri A Kostiainen 1 collaboration

V M Stone 1 collaboration

M M Hankaniemi 1 collaboration

A B Sioofy-Khojine 1 collaboration

A Lin 1 collaboration

I M Diaz Lozano 1 collaboration

M A Mazur 1 collaboration

V Marjomäki 1 collaboration

K Loré 1 collaboration

M Flodström-Tullberg 1 collaboration

Timo Vesikari 1 collaboration

Meri I E Uusi-Mäkelä 1 collaboration

Sanna-Kaisa E Harjula 1 collaboration

Anni K Saralahti 1 collaboration

Kaisa E Oksanen 1 collaboration

Mika Rämet 1 collaboration

Anne Tuukkanen 1 collaboration

Xiaonan Liu 1 collaboration

Adam Orłowski 1 collaboration

Ilpo Vattulainen 1 collaboration

Tomasz Róg 1 collaboration

Dmitri Svergun 1 collaboration

Jussi Lehtonen 1 collaboration

Riitta Veijola 1 collaboration

Johanna Lempainen 1 collaboration

Mikael Knip 1 collaboration

Marta Ripamonti 1 collaboration

Nicolas Liaudet 1 collaboration

Daniel Bouvard 1 collaboration

Tong Gao 1 collaboration

Yijuan Sun 1 collaboration

Alma Yrjänäinen 1 collaboration

Maarit S Patrikainen 1 collaboration

Martti E E Tolvanen 1 collaboration

Alessio Nocentini 1 collaboration

Karolina Pavic 1 collaboration

Nikhil Gupta 1 collaboration

Judit Domènech Omella 1 collaboration

Rita Derua 1 collaboration

Anna Aakula 1 collaboration

Riikka Huhtaniemi 1 collaboration

Juha A Määttä 1 collaboration

Nico Höfflin 1 collaboration

Juha Okkeri 1 collaboration

Zhizhi Wang 1 collaboration

Otto Kauko 1 collaboration

Roosa Varjus 1 collaboration

Henrik Honkanen 1 collaboration

Daniel Abankwa 1 collaboration

Maja Köhn 1 collaboration

Wenqing Xu 1 collaboration

Jakob Nilsson 1 collaboration

Rebecca Page 1 collaboration

Veerle Janssens 1 collaboration

Alexander Leitner 1 collaboration

Jukka Westermarck 1 collaboration

Susan K Vester 1 collaboration

Chasity P Janosko 1 collaboration

Alexander Deiters 1 collaboration

Mark Howarth 1 collaboration

Fernanda Muñoz Caro 1 collaboration

Elke Oberbichler 1 collaboration

Maria Wiesauer 1 collaboration

Eva Schlögl 1 collaboration

Jessica Stangl 1 collaboration

Felix Faschinger 1 collaboration

Günther Knör 1 collaboration

Hermann J Gruber 1 collaboration

Tanja Andrejeff 1 collaboration

Mateusz Sikora 1 collaboration

Jonathan J Booth 1 collaboration

Marek Cieplak 1 collaboration

Dmitrii V Shalashilin 1 collaboration

Ngoc Huynh 1 collaboration

Jonathan M Massera 1 collaboration

Neil J Ball 1 collaboration

Giovanni Bussi 1 collaboration

N V V Jouppila 1 collaboration

J Lehtonen 1 collaboration

E Seppälä 1 collaboration

L Puustinen 1 collaboration

S Oikarinen 1 collaboration

M Knip 1 collaboration

Iftekhar Chowdhury 1 collaboration

Antti Vasala 1 collaboration

Magdalena A Mazur 1 collaboration

Tytti Vuorinen 1 collaboration

Mo A Baikoghli 1 collaboration

Li Xing 1 collaboration

Outi Väätäinen 1 collaboration

Amirbabak Sioofy-Khojine 1 collaboration

Tingwei Ou 1 collaboration

Brandon Anson 1 collaboration