School of Ophthalmology and Optometry, The Eye Hospital of Wenzhou Medical University, No. 270, Xueyuan Road, Wenzhou, Zhejiang 325027, China. higuchi@wmu.edu.cn chenhao@mail.eye.ac.cn and Department of Chemical and Materials Engineering, National Central University, No. 300, Jhongda Rd, Jhongli, Taoyuan 32001, Taiwan. higuchi@ncu.edu.tw.