Tyler Malys

Affiliations

DMS Applied Information and Management Sciences, Frederick National Laboratory for Cancer Research, Frederick, Maryland, USA.

Publications (9)

Antibody-mediated depletion of viral reservoirs is limited in SIV-infected macaques treated early with antiretroviral therapy.

The Journal of clinical investigation

Avec: Adrienne E Swanstrom , Taina T Immonen , Kelli Oswald , Cathi Pyle , James A Thomas , William J Bosche , Lorna Silipino , Michael Hull , Laura Newman , Vicky Coalter , Adam Wiles , Rodney Wiles , Jacob Kiser , David R Morcock , Rebecca Shoemaker , Randy Fast , Matthew W Breed , Joshua Kramer , Duncan Donohue , Christine M Fennessey , Charles M Trubey , Claire Deleage , Jacob D Estes , Jeffrey D Lifson , Brandon F Keele , Gregory Q Del Prete

PKM2 dictates the poised chromatin state of

NAR cancer

Avec: Madhura R Pandkar , Adarsh Raveendran , Kajal Biswas , Srinivas Abhishek Mutnuru , Jharna Mishra , Atul Samaiya , Alexander Y Mitrophanov , Shyam K Sharan , Sanjeev Shukla

Sequencing-based functional assays for classification of BRCA2 variants in mouse ESCs.

Cell reports methods

Avec: Kajal Biswas , Alexander Y Mitrophanov , Sounak Sahu , Teresa Sullivan , Eileen Southon , Darryl Nousome , Susan Reid , Sakshi Narula , Julia Smolen , Trisha Sengupta , Maximilian Riedel-Topper , Medha Kapoor , Anav Babbar , Stacey Stauffer , Linda Cleveland , Mayank Tandon , Shyam K Sharan

Multicolor flow cytometry-based immunophenotyping for preclinical characterization of nanotechnology-based formulations: an insight into structure activity relationship and nanoparticle biocompatibility profiles.

Frontiers in allergy

Avec: Hannah S Newton , Jenny Zhang , Duncan Donohue , Ragi Unnithan , Edward Cedrone , Jie Xu , Alison Vermilya , Jeffrey D Clogston , Marina A Dobrovolskaia

Gynecologic Cancer InterGroup CA125 response has a high negative predictive value for CHK1 inhibitor RECIST response in recurrent ovarian cancer.

Scientific reports

Avec: Kristen R Ibanez , Duncan Donohue , Jung-Min Lee

Mismatch repair protein MLH1 suppresses replicative stress in BRCA2 deficient breast tumors.

The Journal of clinical investigation

Avec: Satheesh K Sengodan , Xiaoju Hu , Vaishnavi Peddibhotla , Kuppusamy Balamurugan , Alexander Y Mitrophanov , Lois McKennett , Suhas S Kharat , Rahul Sanawar , Vinod Kumar Singh , Mary E Albaugh , Sandra S Burkett , Yongmei Zhao , Bao Tran , Esta Sterneck , Subhajyoti De , Shyam K Sharan

The CHK1 inhibitor prexasertib in BRCA wild-type platinum-resistant recurrent high-grade serous ovarian carcinoma: a phase 2 trial.

Nature communications

Avec: Elena Giudice , Tzu-Ting Huang , Jayakumar R Nair , Grant Zurcher , Ann McCoy , Darryl Nousome , Marc R Radke , Elizabeth M Swisher , Stanley Lipkowitz , Kristen Ibanez , Duncan Donohue , Min-Jung Lee , Bernadette Redd , Elliot Levy , Shraddha Rastogi , Nahoko Sato , Jane B Trepel , Jung-Min Lee

TLR7 agonist administration to SIV-infected macaques receiving early initiated cART does not induce plasma viremia.

JCI insight

Avec: Gregory Q Del Prete , W Gregory Alvord , Yuan Li , Claire Deleage , Mukta Nag , Kelli Oswald , James A Thomas , Cathi Pyle , William J Bosche , Vicky Coalter , Adam Wiles , Rodney Wiles , Brian Berkemeier , Michael Hull , Elizabeth Chipriano , Lorna Silipino , Randy Fast , Jacob Kiser , Rebecca Kiser , Joshua Kramer , Matthew W Breed , Charles M Trubey , Jacob D Estes , Tiffany L Barnes , Joseph Hesselgesser , Romas Geleziunas , Jeffrey D Lifson

Saturation genome editing of 11 codons and exon 13 of BRCA2 coupled with chemotherapeutic drug response accurately determines pathogenicity of variants.

PLoS genetics

Avec: Sounak Sahu , Teresa L Sullivan , Alexander Y Mitrophanov , Mélissa Galloux , Darryl Nousome , Eileen Southon , Dylan Caylor , Arun Prakash Mishra , Christine N Evans , Michelle E Clapp , Sandra Burkett , Raj Chari , Kajal Biswas , Shyam K Sharan

Réseau de co-auteurs

Duncan Donohue 4 collaborations

Alexander Y Mitrophanov 4 collaborations

Shyam K Sharan 4 collaborations

Kajal Biswas 3 collaborations

Darryl Nousome 3 collaborations

Kelli Oswald 2 collaborations

Cathi Pyle 2 collaborations

James A Thomas 2 collaborations

William J Bosche 2 collaborations

Lorna Silipino 2 collaborations

Michael Hull 2 collaborations

Vicky Coalter 2 collaborations

Adam Wiles 2 collaborations

Rodney Wiles 2 collaborations

Jacob Kiser 2 collaborations

Randy Fast 2 collaborations

Matthew W Breed 2 collaborations

Joshua Kramer 2 collaborations

Charles M Trubey 2 collaborations

Claire Deleage 2 collaborations

Jacob D Estes 2 collaborations

Jeffrey D Lifson 2 collaborations

Gregory Q Del Prete 2 collaborations

Sounak Sahu 2 collaborations

Eileen Southon 2 collaborations

Jung-Min Lee 2 collaborations

Adrienne E Swanstrom 1 collaboration

Taina T Immonen 1 collaboration

Laura Newman 1 collaboration

David R Morcock 1 collaboration

Rebecca Shoemaker 1 collaboration

Christine M Fennessey 1 collaboration

Brandon F Keele 1 collaboration

Madhura R Pandkar 1 collaboration

Adarsh Raveendran 1 collaboration

Srinivas Abhishek Mutnuru 1 collaboration

Jharna Mishra 1 collaboration

Atul Samaiya 1 collaboration

Sanjeev Shukla 1 collaboration

Teresa Sullivan 1 collaboration

Susan Reid 1 collaboration

Sakshi Narula 1 collaboration

Julia Smolen 1 collaboration

Trisha Sengupta 1 collaboration

Maximilian Riedel-Topper 1 collaboration

Medha Kapoor 1 collaboration

Anav Babbar 1 collaboration

Stacey Stauffer 1 collaboration

Linda Cleveland 1 collaboration

Mayank Tandon 1 collaboration

Hannah S Newton 1 collaboration

Jenny Zhang 1 collaboration

Ragi Unnithan 1 collaboration

Edward Cedrone 1 collaboration

Jie Xu 1 collaboration

Alison Vermilya 1 collaboration

Jeffrey D Clogston 1 collaboration

Marina A Dobrovolskaia 1 collaboration

Kristen R Ibanez 1 collaboration

Satheesh K Sengodan 1 collaboration

Xiaoju Hu 1 collaboration

Vaishnavi Peddibhotla 1 collaboration

Kuppusamy Balamurugan 1 collaboration

Lois McKennett 1 collaboration

Suhas S Kharat 1 collaboration

Rahul Sanawar 1 collaboration

Vinod Kumar Singh 1 collaboration

Mary E Albaugh 1 collaboration

Sandra S Burkett 1 collaboration

Yongmei Zhao 1 collaboration

Bao Tran 1 collaboration

Esta Sterneck 1 collaboration

Subhajyoti De 1 collaboration

Elena Giudice 1 collaboration

Tzu-Ting Huang 1 collaboration

Jayakumar R Nair 1 collaboration

Grant Zurcher 1 collaboration

Ann McCoy 1 collaboration

Marc R Radke 1 collaboration

Elizabeth M Swisher 1 collaboration

Stanley Lipkowitz 1 collaboration

Kristen Ibanez 1 collaboration

Min-Jung Lee 1 collaboration

Bernadette Redd 1 collaboration

Elliot Levy 1 collaboration

Shraddha Rastogi 1 collaboration

Nahoko Sato 1 collaboration

Jane B Trepel 1 collaboration

W Gregory Alvord 1 collaboration

Yuan Li 1 collaboration

Mukta Nag 1 collaboration

Brian Berkemeier 1 collaboration

Elizabeth Chipriano 1 collaboration

Rebecca Kiser 1 collaboration

Tiffany L Barnes 1 collaboration

Joseph Hesselgesser 1 collaboration

Romas Geleziunas 1 collaboration

Teresa L Sullivan 1 collaboration

Mélissa Galloux 1 collaboration

Dylan Caylor 1 collaboration

Arun Prakash Mishra 1 collaboration

Christine N Evans 1 collaboration

Michelle E Clapp 1 collaboration

Sandra Burkett 1 collaboration

Raj Chari 1 collaboration