Toshiaki Sawatani

Affiliations

Department of Pharmacology, School of Pharmaceutical Sciences, University of Shizuoka, Shizuoka, 422-8526, Japan.

Publications (35)

The sialidase inhibitor 2,3-dehydro-2-deoxy-N-acetylneuraminic acid is a glucose-dependent potentiator of insulin secretion.

Scientific reports

Avec: Akira Minami , Yuka Fujita , Sumika Shimba , Mako Shiratori , Yukiko K Kaneko , Tadamune Otsubo , Kiyoshi Ikeda , Hiroaki Kanazawa , Yasuyo Mikami , Risa Sekita , Yuuki Kurebayashi , Tadanobu Takahashi , Taeko Miyagi , Tomohisa Ishikawa , Takashi Suzuki

Time-dependent changes in plasma xanthine oxidoreductase during hospitalization of acute heart failure.

ESC heart failure

Avec: Hirotake Okazaki , Akihiro Shirakabe , Masato Matsushita , Yusaku Shibata , Shota Shigihara , Tomofumi Sawatani , Kenichi Tani , Kazutaka Kiuchi , Yusuke Otsuka , Takayo Murase , Takashi Nakamura , Nobuaki Kobayashi , Noritake Hata , Kuniya Asai , Wataru Shimizu

DNAJC3 deficiency induces β-cell mitochondrial apoptosis and causes syndromic young-onset diabetes.

European journal of endocrinology

Avec: Maria Lytrivi , Valérie Senée , Paraskevi Salpea , Federica Fantuzzi , Anne Philippi , Baroj Abdulkarim , Sandra Marín-Cañas , Nathalie Pachera , Anne Degavre , Pratibha Singh , Céline Derbois , Doris Lechner , Laurence Ladrière , Mariana Igoillo-Esteve , Cristina Cosentino , Lorella Marselli , Jean-François Deleuze , Piero Marchetti , Décio L Eizirik , Marc Nicolino , Annabelle Chaussenot , Cécile Julier , Miriam Cnop

Clinical significance of the N-terminal pro-brain natriuretic peptide and B-type natriuretic peptide ratio in the acute phase of acute heart failure.

European heart journal. Acute cardiovascular care

Avec: Tomofumi Sawatani , Akihiro Shirakabe , Hirotake Okazaki , Masato Matsushita , Yusaku Shibata , Shota Shigihara , Yusuke Otsuka , Kazutaka Kiuchi , Nobuaki Kobayashi , Noritake Hata , Wataru Shimizu , Kuniya Asai

YIPF5 mutations cause neonatal diabetes and microcephaly through endoplasmic reticulum stress.

The Journal of clinical investigation

Avec: Elisa De Franco , Maria Lytrivi , Hazem Ibrahim , Hossam Montaser , Matthew N Wakeling , Federica Fantuzzi , Kashyap Patel , Céline Demarez , Ying Cai , Mariana Igoillo-Esteve , Cristina Cosentino , Väinö Lithovius , Helena Vihinen , Eija Jokitalo , Thomas W Laver , Matthew B Johnson , Hadis Shakeri , Nathalie Pachera , Belma Haliloglu , Mehmet Nuri Ozbek , Edip Unal , Ruken Yıldırım , Tushar Godbole , Melek Yildiz , Banu Aydin , Angeline Bilheu , Ikuo Suzuki , Sarah E Flanagan , Pierre Vanderhaeghen , Valérie Senée , Cécile Julier , Piero Marchetti , Decio L Eizirik , Sian Ellard , Jonna Saarimäki-Vire , Timo Otonkoski , Miriam Cnop , Andrew T Hattersley

The Prognostic Impact of Hospital Transfer after Admission due to Acute Heart Failure.

International heart journal

Avec: Kazutaka Kiuchi , Akihiro Shirakabe , Hirotake Okazaki , Masato Matsushita , Yusaku Shibata , Shota Shigihara , Suguru Nishigoori , Tomofumi Sawatani , Yusuke Otsuka , Hiroto Kokubun , Tomoyo Miyakuni , Nobuaki Kobayashi , Kuniya Asai , Wataru Shimizu

Evaluation of Plasma Xanthine Oxidoreductase (XOR) Activity in Patients with Cardiopulmonary Arrest.

International heart journal

Avec: Yusaku Shibata , Akihiro Shirakabe , Hirotake Okazaki , Masato Matsushita , Shota Shigihara , Suguru Nishigoori , Tomofumi Sawatani , Kazutaka Kiuchi , Masahito Takahashi , Takayo Murase , Takashi Nakamura , Nobuaki Kobayashi , Kuniya Asai

Clinical Significance of the Fibrosis-4 Index in Patients with Acute Heart Failure Requiring Intensive Care.

International heart journal

Avec: Akihiro Shirakabe , Hirotake Okazaki , Masato Matsushita , Yusaku Shibata , Shota Shigihara , Suguru Nishigoori , Tomofumi Sawatani , Kenichi Tani , Kazutaka Kiuchi , Yusuke Otsuka , Masanori Atsukawa , Norio Itokawa , Taeang Arai , Nobuaki Kobayashi , Kuniya Asai , Wataru Shimizu

Mining the transcriptome of target tissues of autoimmune and degenerative pancreatic β-cell and brain diseases to discover therapies.

iScience

Avec: Xiaoyan Yi , Bianca Marmontel de Souza , Florian Szymczak , Lorella Marselli , Piero Marchetti , Miriam Cnop , Decio L Eizirik

Clinical Significance of the Triglyceride-Glucose Index in Patients Requiring Nonsurgical Intensive Care.

International heart journal

Avec: Suguru Nishigoori , Akihiro Shirakabe , Hirotake Okazaki , Masato Matsushita , Yusaku Shibata , Shota Shigihara , Tomofumi Sawatani , Kenichi Tani , Kazutaka Kiuchi , Nobuaki Kobayashi , Kuniya Asai

Dual effect of reduced type I diacylglycerol kinase activity on insulin secretion from MIN6 β-cells.

Journal of pharmacological sciences

Avec: Yukiko K Kaneko , Tomohisa Ishikawa

The prognostic impact of the serum heart-type fatty acid-binding protein level in patients with sepsis who were admitted to the non-surgical intensive-care unit.

Heart and vessels

Avec: Kenichi Tani , Akihiro Shirakabe , Nobuaki Kobayashi , Hirotake Okazaki , Masato Matsushita , Yusaku Shibata , Shota Shigihara , Tomofumi Sawatani , Yusuke Otsuka , Tsutomu Takayasu , Miwako Asano , Akiko Nomura , Noritake Hata , Kuniya Asai , Wataru Shimizu

Time-Dependent Changes in N-Terminal Pro-Brain Natriuretic Peptide and B-Type Natriuretic Peptide Ratio During Hospitalization for Acute Heart Failure.

International heart journal

Avec: Tomofumi Sawatani , Akihiro Shirakabe , Hirotake Okazaki , Masato Matsushita , Yusaku Shibata , Shota Shigihara , Suguru Nishigoori , Nozomi Sasamoto , Kazutaka Kiuchi , Nobuaki Kobayashi , Wataru Shimizu , Kuniya Asai

GLP-1R agonists demonstrate potential to treat Wolfram syndrome in human preclinical models.

Diabetologia

Avec: Vyron Gorgogietas , Bahareh Rajaei , Chae Heeyoung , Bruno J Santacreu , Sandra Marín-Cañas , Paraskevi Salpea , Anyishai Musuaya , María N Arroyo , Cristina Moreno-Castro , Khadija Benabdallah , Celine Demarez , Sanna Toivonen , Cristina Cosentino , Nathalie Pachera , Maria Lytrivi , Ying Cai , Lode Carnel , Cris Brown , Fumihiko Urano , Piero Marchetti , Patrick Gilon , Decio L Eizirik , Miriam Cnop , Mariana Igoillo-Esteve

Organ dysfunction, injury, and failure in cardiogenic shock.

Journal of intensive care

Avec: Akihiro Shirakabe , Masato Matsushita , Yusaku Shibata , Shota Shighihara , Suguru Nishigoori , Tomofumi Sawatani , Kazutaka Kiuchi , Kuniya Asai

LncRNA ARGI Contributes to Virus-Induced Pancreatic β Cell Inflammation Through Transcriptional Activation of IFN-Stimulated Genes.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Avec: Itziar González-Moro , Koldo Garcia-Etxebarria , Luis Manuel Mendoza , Nora Fernández-Jiménez , Jon Mentxaka , Ane Olazagoitia-Garmendia , María Nicol Arroyo , Cristina Moreno-Castro , Chiara Vinci , Anne Op de Beek , Miriam Cnop , Mariana Igoillo-Esteve , Izortze Santin

Thoracoscopic esophageal drainage for tracheal compression due to mucocele after esophagogastric bypass: a case report.

Surgical case reports

Avec: Takeshi Yamashita , Koji Otsuka , Satoru Goto , Tomotake Ariyoshi , Kentaro Motegi , Masahiro Kohmoto , Akira Saito , Koichiro Fujimasa , Yoshihito Sato , Rei Kato , Tetsuo Sawatani , Masahiko Murakami

Ten-year trends in non-surgical patients requiring intensive care: Long-term prognostic differences by year of admission.

Journal of cardiology

Avec: Shota Shigihara , Akihiro Shirakabe , Masato Matsushita , Suguru Nishigoori , Tomofumi Sawatani , Kenichi Tani , Kazutaka Kiuchi , Riku Toguchi , Shohei Kawakami , Yu Michiura , Mana Sawahata , Nobuaki Kobayashi , Kuniya Asai

Worsening renal failure in patients with acute heart failure: the importance of cardiac biomarkers.

ESC heart failure

Avec: Akihiro Shirakabe , Noritake Hata , Nobuaki Kobayashi , Hirotake Okazaki , Masato Matsushita , Yusaku Shibata , Saori Uchiyama , Tomofumi Sawatani , Kuniya Asai , Wataru Shimizu

The prognostic impact of the uric acid level in patients who require cardiovascular intensive care - is serum uric acid a surrogate biomarker for critical patients in the non-surgical intensive care unit?

European heart journal. Acute cardiovascular care

Avec: Yusaku Shibata , Akihiro Shirakabe , Hirotake Okazaki , Masato Matsushita , Tomofumi Sawatani , Saori Uchiyama , Kenichi Tani , Nobuaki Kobayashi , Toshiaki Otsuka , Noritake Hata , Kuniya Asai , Wataru Shimizu

Plasma xanthine oxidoreductase activity in patients with decompensated acute heart failure requiring intensive care.

ESC heart failure

Avec: Hirotake Okazaki , Akihiro Shirakabe , Masato Matsushita , Yusaku Shibata , Tomofumi Sawatani , Saori Uchiyama , Kennichi Tani , Takayo Murase , Takashi Nakamura , Tsutomu Takayasu , Miwako Asano , Nobuaki Kobayashi , Noritake Hata , Kuniya Asai , Wataru Shimizu

Successful Treatment of Thrombocytopenia, Anasarca, Fever, Reticulin Myelofibrosis/Renal Insufficiency, and Organomegaly Syndrome Using Plasma Exchange Followed by Rituximab in the Intensive Care Unit.

Journal of medical cases

Avec: Yusuke Otsuka , Akihiro Shirakabe , Toshio Asayama , Hirotake Okazaki , Yusaku Shibata , Shota Shigihara , Tomofumi Sawatani , Norio Yokose , Kuniya Asai

[Lateral Port Site Hernia Following Robot Assisted Laparoscopic Radical Prostatectomy : A Case Report and Literature Review].

Hinyokika kiyo. Acta urologica Japonica

Avec: Shunsuke Hori , Hideo Otsuki , Tetsuo Sawatani , Mitsuru/Nakajima Oshiro , Yozo Mitsui

Type III procollagen peptide level can indicate liver dysfunction associated with volume overload in acute heart failure.

ESC heart failure

Avec: Akihiro Shirakabe , Hirotake Okazaki , Masato Matsushita , Yusaku Shibata , Shota Shigihara , Suguru Nishigoori , Tomofumi Sawatani , Nozomi Sasamoto , Kazutaka Kiuchi , Masanori Atsukawa , Norio Itokawa , Taeang Arai , Nobuaki Kobayashi , Kuniya Asai

Effect of sacubitril/valsartan on natriuretic peptide in patients with compensated heart failure.

Heart and vessels

Avec: Akihiro Shirakabe , Masato Matsushita , Tomofumi Sawatani , Satsuki Noma , Tsutomu Takayasu , Hideki Kanai , Miwako Asano , Akiko Nomura , Kuniya Asai

Late Kidney Injury After Admission to Intensive Care Unit for Acute Heart Failure.

International heart journal

Avec: Masaki Morooka , Akihiro Shirakabe , Hirotake Okazaki , Masato Matsushita , Shota Shigihara , Suguru Nishigoori , Tomofumi Sawatani , Kenichi Tani , Kazutaka Kiuchi , Shohei Kawakami , Yu Michiura , Shogo Kamitani , Nobuaki Kobayashi , Kuniya Asai

Towards a Functional Cure for Diabetes Using Stem Cell-Derived Beta Cells: Are We There Yet?

Cells

Avec: Stephanie Bourgeois , Annelore Van Mulders , Nico De Leu , Yves Heremans , Harry Heimberg , Miriam Cnop , Willem Staels

TRPV2 channels mediate insulin secretion induced by cell swelling in mouse pancreatic β-cells.

American journal of physiology. Cell physiology

Avec: Yukiko K Kaneko , Isao Doutsu , Ai Ogawa , Tomohisa Ishikawa

[Involvement of Diacylglycerol Kinase on the Regulation of Insulin Secretion in Pancreatic β-Cells during Type 2 Diabetes].

Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan

Avec: Yukiko K Kaneko , Tomohisa Ishikawa

Fibrinogen-to-Albumin Ratio in Patients with Acute Heart Failure.

International heart journal

Avec: Tomofumi Sawatani , Akihiro Shirakabe , Shota Shighihara , Suguru Nishigoori , Kazutaka Kiuchi , Kenichi Tani , Shohei Kawakami , Yu Michiura , Shogo Kamitani , Toshiaki Otsuka , Nobuaki Kobayashi , Kuniya Asai

Inhibition of the type 1 diabetes candidate gene PTPN2 aggravates TNF-α-induced human beta cell dysfunction and death.

Diabetologia

Avec: Arturo Roca-Rivada , Sandra Marín-Cañas , Maikel L Colli , Chiara Vinci , Lorella Marselli , Miriam Cnop , Piero Marchetti , Decio L Eizirik

Trends in Sudden Death Following Admission for Acute Heart Failure.

The American journal of cardiology

Avec: Suguru Nishigoori , Akihiro Shirakabe , Hirotake Okazaki , Masato Matsushita , Yusaku Shibata , Shota Shighihara , Tomofumi Sawatani , Kazutaka Kiuchi , Nozomi Sasamoto , Nobuaki Kobayashi , Wataru Shimizu , Kuniya Asai

EndoC-βH5 cells are storable and ready-to-use human pancreatic beta cells with physiological insulin secretion.

Molecular metabolism

Avec: Bruno Blanchi , Marion Taurand , Claire Colace , Sofia Thomaidou , Charlotte Audeoud , Federica Fantuzzi , Sevda Gheibi , Joan Sabadell-Basallote , Fransje W J Boot , Thibault Chantier , Aline Piet , Charlotte Cavanihac , Marion Pilette , Adélie Balguerie , Hamza Olleik , Françoise Carlotti , Miriam Ejarque , Malin Fex , Hindrik Mulder , Miriam Cnop , Decio L Eizirik , Ouardane Jouannot , Anne-Lise Gaffuri , Paul Czernichow , Arnaud Zaldumbide , Raphaël Scharfmann , Philippe Ravassard

Inferring regulators of cell identity in the human adult pancreas.

NAR genomics and bioinformatics

Avec: Lotte Vanheer , Federica Fantuzzi , San Kit To , Andrea Schiavo , Matthias Van Haele , Tessa Ostyn , Tine Haesen , Xiaoyan Yi , Adrian Janiszewski , Joel Chappell , Adrien Rihoux , Tania Roskams , Francois Pattou , Julie Kerr-Conte , Miriam Cnop , Vincent Pasque

Timing and Degree of Acute Kidney Injury in Patients Requiring Non-Surgical Intensive Care.

Circulation journal : official journal of the Japanese Circulation Society

Avec: Akihiro Shirakabe , Hirotake Okazaki , Masato Matsushita , Yusaku Shibata , Shota Shigihara , Suguru Nishigoori , Tomofumi Sawatani , Kenichi Tani , Kazutaka Kiuchi , Nobuaki Kobayashi , Kuniya Asai

Réseau de co-auteurs

Akihiro Shirakabe 20 collaborations

Tomofumi Sawatani 20 collaborations

Kuniya Asai 20 collaborations

Masato Matsushita 18 collaborations

Nobuaki Kobayashi 17 collaborations

Hirotake Okazaki 16 collaborations

Yusaku Shibata 16 collaborations

Kazutaka Kiuchi 14 collaborations

Shota Shigihara 13 collaborations

Suguru Nishigoori 12 collaborations

Wataru Shimizu 10 collaborations

Kenichi Tani 9 collaborations

Miriam Cnop 9 collaborations

Yusuke Otsuka 6 collaborations

Noritake Hata 6 collaborations

Piero Marchetti 5 collaborations

Decio L Eizirik 5 collaborations

Yukiko K Kaneko 4 collaborations

Tomohisa Ishikawa 4 collaborations

Federica Fantuzzi 4 collaborations

Mariana Igoillo-Esteve 4 collaborations

Takayo Murase 3 collaborations

Takashi Nakamura 3 collaborations

Maria Lytrivi 3 collaborations

Sandra Marín-Cañas 3 collaborations

Nathalie Pachera 3 collaborations

Cristina Cosentino 3 collaborations

Lorella Marselli 3 collaborations

Tsutomu Takayasu 3 collaborations

Miwako Asano 3 collaborations

Nozomi Sasamoto 3 collaborations

Shota Shighihara 3 collaborations

Shohei Kawakami 3 collaborations

Yu Michiura 3 collaborations

Saori Uchiyama 3 collaborations

Valérie Senée 2 collaborations

Paraskevi Salpea 2 collaborations

Cécile Julier 2 collaborations

Ying Cai 2 collaborations

Masanori Atsukawa 2 collaborations

Norio Itokawa 2 collaborations

Taeang Arai 2 collaborations

Xiaoyan Yi 2 collaborations

Akiko Nomura 2 collaborations

Cristina Moreno-Castro 2 collaborations

Chiara Vinci 2 collaborations

Tetsuo Sawatani 2 collaborations

Toshiaki Otsuka 2 collaborations

Shogo Kamitani 2 collaborations

Akira Minami 1 collaboration

Yuka Fujita 1 collaboration

Sumika Shimba 1 collaboration

Mako Shiratori 1 collaboration

Tadamune Otsubo 1 collaboration

Kiyoshi Ikeda 1 collaboration

Hiroaki Kanazawa 1 collaboration

Yasuyo Mikami 1 collaboration

Risa Sekita 1 collaboration

Yuuki Kurebayashi 1 collaboration

Tadanobu Takahashi 1 collaboration

Taeko Miyagi 1 collaboration

Takashi Suzuki 1 collaboration

Anne Philippi 1 collaboration

Baroj Abdulkarim 1 collaboration

Anne Degavre 1 collaboration

Pratibha Singh 1 collaboration

Céline Derbois 1 collaboration

Doris Lechner 1 collaboration

Laurence Ladrière 1 collaboration

Jean-François Deleuze 1 collaboration

Décio L Eizirik 1 collaboration

Marc Nicolino 1 collaboration

Annabelle Chaussenot 1 collaboration

Elisa De Franco 1 collaboration

Hazem Ibrahim 1 collaboration

Hossam Montaser 1 collaboration

Matthew N Wakeling 1 collaboration

Kashyap Patel 1 collaboration

Céline Demarez 1 collaboration

Väinö Lithovius 1 collaboration

Helena Vihinen 1 collaboration

Eija Jokitalo 1 collaboration

Thomas W Laver 1 collaboration

Matthew B Johnson 1 collaboration

Hadis Shakeri 1 collaboration

Belma Haliloglu 1 collaboration

Mehmet Nuri Ozbek 1 collaboration

Edip Unal 1 collaboration

Ruken Yıldırım 1 collaboration

Tushar Godbole 1 collaboration

Melek Yildiz 1 collaboration

Banu Aydin 1 collaboration

Angeline Bilheu 1 collaboration

Ikuo Suzuki 1 collaboration

Sarah E Flanagan 1 collaboration

Pierre Vanderhaeghen 1 collaboration

Sian Ellard 1 collaboration

Jonna Saarimäki-Vire 1 collaboration

Timo Otonkoski 1 collaboration

Andrew T Hattersley 1 collaboration

Hiroto Kokubun 1 collaboration

Tomoyo Miyakuni 1 collaboration

Masahito Takahashi 1 collaboration

Bianca Marmontel de Souza 1 collaboration

Florian Szymczak 1 collaboration

Vyron Gorgogietas 1 collaboration

Bahareh Rajaei 1 collaboration

Chae Heeyoung 1 collaboration

Bruno J Santacreu 1 collaboration

Anyishai Musuaya 1 collaboration

María N Arroyo 1 collaboration

Khadija Benabdallah 1 collaboration

Celine Demarez 1 collaboration

Sanna Toivonen 1 collaboration

Lode Carnel 1 collaboration

Cris Brown 1 collaboration

Fumihiko Urano 1 collaboration

Patrick Gilon 1 collaboration

Itziar González-Moro 1 collaboration

Koldo Garcia-Etxebarria 1 collaboration

Luis Manuel Mendoza 1 collaboration

Nora Fernández-Jiménez 1 collaboration

Jon Mentxaka 1 collaboration

Ane Olazagoitia-Garmendia 1 collaboration

María Nicol Arroyo 1 collaboration

Anne Op de Beek 1 collaboration

Izortze Santin 1 collaboration

Takeshi Yamashita 1 collaboration

Koji Otsuka 1 collaboration

Satoru Goto 1 collaboration

Tomotake Ariyoshi 1 collaboration

Kentaro Motegi 1 collaboration

Masahiro Kohmoto 1 collaboration

Akira Saito 1 collaboration

Koichiro Fujimasa 1 collaboration

Yoshihito Sato 1 collaboration

Rei Kato 1 collaboration

Masahiko Murakami 1 collaboration

Riku Toguchi 1 collaboration

Mana Sawahata 1 collaboration

Kennichi Tani 1 collaboration

Toshio Asayama 1 collaboration

Norio Yokose 1 collaboration

Shunsuke Hori 1 collaboration

Hideo Otsuki 1 collaboration

Mitsuru/Nakajima Oshiro 1 collaboration

Yozo Mitsui 1 collaboration

Satsuki Noma 1 collaboration

Hideki Kanai 1 collaboration

Masaki Morooka 1 collaboration

Stephanie Bourgeois 1 collaboration

Annelore Van Mulders 1 collaboration

Nico De Leu 1 collaboration

Yves Heremans 1 collaboration

Harry Heimberg 1 collaboration

Willem Staels 1 collaboration

Isao Doutsu 1 collaboration

Ai Ogawa 1 collaboration

Arturo Roca-Rivada 1 collaboration

Maikel L Colli 1 collaboration

Bruno Blanchi 1 collaboration

Marion Taurand 1 collaboration

Claire Colace 1 collaboration

Sofia Thomaidou 1 collaboration

Charlotte Audeoud 1 collaboration

Sevda Gheibi 1 collaboration

Joan Sabadell-Basallote 1 collaboration

Fransje W J Boot 1 collaboration

Thibault Chantier 1 collaboration

Aline Piet 1 collaboration

Charlotte Cavanihac 1 collaboration

Marion Pilette 1 collaboration

Adélie Balguerie 1 collaboration

Hamza Olleik 1 collaboration

Françoise Carlotti 1 collaboration

Miriam Ejarque 1 collaboration

Malin Fex 1 collaboration

Hindrik Mulder 1 collaboration

Ouardane Jouannot 1 collaboration

Anne-Lise Gaffuri 1 collaboration

Paul Czernichow 1 collaboration

Arnaud Zaldumbide 1 collaboration

Raphaël Scharfmann 1 collaboration

Philippe Ravassard 1 collaboration

Lotte Vanheer 1 collaboration

San Kit To 1 collaboration

Andrea Schiavo 1 collaboration

Matthias Van Haele 1 collaboration

Tessa Ostyn 1 collaboration

Tine Haesen 1 collaboration

Adrian Janiszewski 1 collaboration

Joel Chappell 1 collaboration

Adrien Rihoux 1 collaboration

Tania Roskams 1 collaboration

Francois Pattou 1 collaboration

Julie Kerr-Conte 1 collaboration

Vincent Pasque 1 collaboration