Thomas J Macartney

Affiliations

Medical Research Council Protein Phosphorylation and Ubiquitylation Unit, University of Dundee, Dundee, UK.

Publications (9)

Targeting Endogenous K-RAS for Degradation through the Affinity-Directed Protein Missile System.

Cell chemical biology

Avec: Sascha Röth , Agnieszka Konopacka , Kwok-Ho Chan , Houjiang Zhou , Markus A Queisser , Gopal P Sapkota

FAM83D directs protein kinase CK1α to the mitotic spindle for proper spindle positioning.

EMBO reports

Avec: Luke J Fulcher , Zhengcheng He , Lin Mei , Nicola T Wood , Alan R Prescott , Arlene J Whigham , Joby Varghese , Robert Gourlay , Graeme Ball , Rosemary Clarke , David G Campbell , Christopher A Maxwell , Gopal P Sapkota

A conserved ATG2-GABARAP family interaction is critical for phagophore formation.

EMBO reports

Avec: Mihaela Bozic , Luuk van den Bekerom , Beth A Milne , Nicola Goodman , Lisa Roberston , Alan R Prescott , Nina Dawe , David G McEwan

Harnessing nanobodies for target protein degradation through the Affinity-directed PROtein Missile (AdPROM) system.

Methods in enzymology

Avec: Bill Carton , Sascha Röth , Gopal P Sapkota

Identification of KLHDC2 as an efficient proximity-induced degrader of K-RAS, STK33, β-catenin, and FoxP3.

Cell chemical biology

Avec: Sascha Röth , Nur Mehpare Kocaturk , Preethi S Sathyamurthi , Bill Carton , Matthew Watt , Kwok-Ho Chan , Albert Isidro-Llobet , Agnieszka Konopacka , Markus A Queisser , Gopal P Sapkota

A novel FAM83G variant from palmoplantar keratoderma patient disrupts WNT signalling via loss of FAM83G-CK1α interaction.

Open biology

Avec: Lorraine Glennie , Marta Codina Solà , Mar Xunclà , Gloria Aparicio Español , Elena Garcia-Arumí , Eduardo Fidel Tizzano , Nicola T Wood , Amaia Lasa-Aranzasti , Gopal P Sapkota

FAM83F regulates canonical Wnt signalling through an interaction with CK1α.

Life science alliance

Avec: Karen Dunbar , Rebecca A Jones , Kevin Dingwell , James C Smith , Gopal P Sapkota

IMiDs induce FAM83F degradation via an interaction with CK1α to attenuate Wnt signalling.

Life science alliance

Avec: Karen Dunbar , Gopal P Sapkota

Targeted dephosphorylation of TFEB promotes its nuclear translocation.

iScience

Avec: Jin-Feng Zhao , Natalia Shpiro , Gajanan Sathe , Abigail Brewer , Nicola T Wood , Florentina Negoita , Kei Sakamoto , Gopal P Sapkota

Réseau de co-auteurs

Gopal P Sapkota 8 collaborations

Sascha Röth 3 collaborations

Nicola T Wood 3 collaborations

Agnieszka Konopacka 2 collaborations

Kwok-Ho Chan 2 collaborations

Markus A Queisser 2 collaborations

Alan R Prescott 2 collaborations

Bill Carton 2 collaborations

Karen Dunbar 2 collaborations

Houjiang Zhou 1 collaboration

Luke J Fulcher 1 collaboration

Zhengcheng He 1 collaboration

Lin Mei 1 collaboration

Arlene J Whigham 1 collaboration

Joby Varghese 1 collaboration

Robert Gourlay 1 collaboration

Graeme Ball 1 collaboration

Rosemary Clarke 1 collaboration

David G Campbell 1 collaboration

Christopher A Maxwell 1 collaboration

Mihaela Bozic 1 collaboration

Luuk van den Bekerom 1 collaboration

Beth A Milne 1 collaboration

Nicola Goodman 1 collaboration

Lisa Roberston 1 collaboration

Nina Dawe 1 collaboration

David G McEwan 1 collaboration

Nur Mehpare Kocaturk 1 collaboration

Preethi S Sathyamurthi 1 collaboration

Matthew Watt 1 collaboration

Albert Isidro-Llobet 1 collaboration

Lorraine Glennie 1 collaboration

Marta Codina Solà 1 collaboration

Mar Xunclà 1 collaboration

Gloria Aparicio Español 1 collaboration

Elena Garcia-Arumí 1 collaboration

Eduardo Fidel Tizzano 1 collaboration

Amaia Lasa-Aranzasti 1 collaboration

Rebecca A Jones 1 collaboration

Kevin Dingwell 1 collaboration

James C Smith 1 collaboration

Jin-Feng Zhao 1 collaboration

Natalia Shpiro 1 collaboration

Gajanan Sathe 1 collaboration

Abigail Brewer 1 collaboration

Florentina Negoita 1 collaboration

Kei Sakamoto 1 collaboration