Thomas Blankenstein

Affiliations

Max-Delbrück-Center for Molecular Medicine (MDC), Robert-Rössle-Straße 10, 13092 Berlin, Germany.
Institute of Immunology, Charité Campus Buch, 13092 Berlin, Germany.

Publications (24)

CD28 Co-Stimulus Achieves Superior CAR T Cell Effector Function against Solid Tumors Than 4-1BB Co-Stimulus.

Cancers

Avec: Ana Textor , Laura Grunewald , Kathleen Anders , Anika Klaus , Silke Schwiebert , Annika Winkler , Maria Stecklum , Jana Rolff , Anton G Henssen , Uta E Höpken , Angelika Eggert , Johannes H Schulte , Michael C Jensen , Annette Künkele

In vitro proteasome processing of neo-splicetopes does not predict their presentation in vivo.

eLife

Avec: Gerald Willimsky , Christin Beier , Lena Immisch , George Papafotiou , Vivian Scheuplein , Andrean Goede , Hermann-Georg Holzhütter , Peter M Kloetzel

H3.3K27M mutation is not a suitable target for immunotherapy in HLA-A2

Journal for immunotherapy of cancer

Avec: Lena Immisch , George Papafotiou , Oliver Popp , Philipp Mertins , Gerald Willimsky

Rapid single-cell identification of Epstein-Barr virus-specific T-cell receptors for cellular therapy.

Cytotherapy

Avec: María Fernanda Lammoglia Cobo , Carlotta Welters , Leonie Rosenberger , Matthias Leisegang , Kerstin Dietze , Christian Pircher , Livius Penter , Regina Gary , Lars Bullinger , Anna Takvorian , Andreas Moosmann , Klaus Dornmair , Thomas Kammertöns , Armin Gerbitz , Leo Hansmann

A phase I study of MAGE-A1-targeted T1367 T-cell receptor-based cell therapy in patients with advanced multiple myeloma.

Haematologica

Avec: Josefine Krüger , Matthias Obenaus , Igor Wolfgang Blau , Dana Hoser , Martin Vaegler , Hana Rauschenbach , Ioannis Anagnostopoulos , Korinna Jöhrens , Vivian Scheuplein , Elisa Kieback , Judith Böhme , Ann-Christin Von Brünneck , Jan Krönke , Antonia Busse , Gerald Willimsky , Antonio Pezzutto , Ulrich Keller , Axel Nogai

Immune Phenotypes and Target Antigens of Clonally Expanded Bone Marrow T Cells in Treatment-Naïve Multiple Myeloma.

Cancer immunology research

Avec: Carlotta Welters , María Fernanda Lammoglia Cobo , Christian Alexander Stein , Meng-Tung Hsu , Amin Ben Hamza , Livius Penter , Xiaojing Chen , Christopher Buccitelli , Oliver Popp , Philipp Mertins , Kerstin Dietze , Lars Bullinger , Andreas Moosmann , Eric Blanc , Dieter Beule , Armin Gerbitz , Julian Strobel , Holger Hackstein , Hans-Peter Rahn , Klaus Dornmair , Leo Hansmann

Virus-reactive T cells expanded in aplastic anemia eliminate hematopoietic progenitor cells by molecular mimicry.

Blood

Avec: Amin Ben Hamza , Carlotta Welters , Serena Stadler , Monika Brüggemann , Kerstin Dietze , Olaf Brauns , Tim H Brümmendorf , Thomas H Winkler , Lars Bullinger , Leonie Rosenberger , Matthias Leisegang , Thomas Kammertöns , Wolfgang Herr , Andreas Moosmann , Julian Strobel , Holger Hackstein , Klaus Dornmair , Fabian Beier , Leo Hansmann

Identification and ranking of recurrent neo-epitopes in cancer.

BMC medical genomics

Avec: Eric Blanc , Manuel Holtgrewe , Arunraj Dhamodaran , Clemens Messerschmidt , Gerald Willimsky , Dieter Beule

Regulation of LCoR and RIP140 expression in cervical intraepithelial neoplasia and correlation with CIN progression and dedifferentiation.

Journal of cancer research and clinical oncology

Avec: Tilman L R Vogelsang , Elisa Schmoeckel , Christina Kuhn , Mina Temelkov , Helene Heidegger , Theresa Maria Kolben , Thomas Kolben , Sven Mahner , Doris Mayr , Udo Jeschke , Aurelia Vattai

The role of CD4 T cells in rejection of solid tumors.

Current opinion in immunology

Avec: Lucia Poncette , Julia Bluhm ,

Long-term in vitro expansion ensures increased yield of central memory T cells as perspective for manufacturing challenges.

International journal of cancer

Avec: Stefanie Herda , Andreas Heimann , Benedikt Obermayer , Elisa Ciraolo , Stefanie Althoff , Josefine Ruß , Corinna Grunert , Antonia Busse , Lars Bullinger , Antonio Pezzutto , Dieter Beule , Il-Kang Na

IFN-γ-dependent tumor-antigen cross-presentation by lymphatic endothelial cells promotes their killing by T cells and inhibits metastasis.

Science advances

Avec: Laure Garnier , Robert Pick , Julien Montorfani , Mengzhu Sun , Dale Brighouse , Nicolas Liaudet , Thomas Kammertoens , Nicolas Page , Jeremiah Bernier-Latamani , Ngoc Lan Tran , Tatiana V Petrova , Doron Merkler , Christoph Scheiermann , Stéphanie Hugues

IFNγ binding to extracellular matrix prevents fatal systemic toxicity.

Nature immunology

Avec: Josephine Kemna , Evelyne Gout , Leon Daniau , Jessica Lao , Kristoffer Weißert , Sandra Ammann , Ralf Kühn , Matthias Richter , Christine Molenda , Anje Sporbert , Dario Zocholl , Robert Klopfleisch , Anja Schütz , Hugues Lortat-Jacob , Peter Aichele , Thomas Kammertoens ,

Interferon-γ Receptor Signaling in Dendritic Cells Restrains Spontaneous Proliferation of CD4

Frontiers in immunology

Avec: Laura Knop , Charlotte Frommer , Diana Stoycheva , Katrin Deiser , Ulrich Kalinke , Thomas Kammertoens , Ildiko Rita Dunay , Thomas Schüler

Effective NY-ESO-1-specific MHC II-restricted T cell receptors from antigen-negative hosts enhance tumor regression.

The Journal of clinical investigation

Avec: Lucia Poncette , Xiaojing Chen , Felix Km Lorenz ,

MRI hip findings in asymptomatic professional rugby players, ballet dancers, and age-matched controls.

Clinical radiology

Avec: T Blankenstein , A Grainger , B Dube , R Evans , P Robinson

Adjuvant radiotherapy and local recurrence in vulvar cancer - a subset analysis of the AGO-CaRE-1 study.

Gynecologic oncology

Avec: Linn Woelber , Katharina Prieske , Christine Zu Eulenburg , Stefanie Corradini , Cordula Petersen , Mareike Bommert , Felix Hilpert , Nikolaus de Gregorio , Severine Iborra , Jalid Sehouli , Atanas Ignatov , Peter Hillemanns , Sophie Fuerst , Hans-Georg Strauss , Klaus Baumann , Matthias W Beckmann , Alexander Mustea , Sven Mahner , Anna Jaeger

Isolation of Neoantigen-Specific Human T Cell Receptors from Different Human and Murine Repertoires.

Cancers

Avec: Corinna Grunert , Gerald Willimsky , Caroline Anna Peuker , Simone Rhein , Leo Hansmann , Eric Blanc , Dieter Beule , Ulrich Keller , Antonio Pezzutto , Antonia Busse

Trauma radiology teaching for foundation doctors working within the Scottish Trauma Network improves radiology requests and patient safety: a multidepartmental quality improvement project.

Postgraduate medical journal

Avec: Sara Caterina Maria O'Rourke , Daniel Christmas , Tom Blankenstein

Localization-associated immune phenotypes of clonally expanded tumor-infiltrating T cells and distribution of their target antigens in rectal cancer.

Oncoimmunology

Avec: Livius Penter , Kerstin Dietze , Julia Ritter , Maria Fernanda Lammoglia Cobo , Josefin Garmshausen , Felix Aigner , Lars Bullinger , Holger Hackstein , Sandra Wienzek-Lischka , Michael Hummel , Klaus Dornmair , Leo Hansmann

SigsPack, a package for cancer mutational signatures.

BMC bioinformatics

Avec: Franziska Schumann , Eric Blanc , Clemens Messerschmidt , Antonia Busse , Dieter Beule

Targeting the recurrent Rac1P29S neoepitope in melanoma with heterologous high-affinity T cell receptors.

Frontiers in immunology

Avec: Lena Immisch , George Papafotiou , Nerea Gallarín Delgado , Vivian Scheuplein , Annette Paschen , Gerald Willimsky

Generation of TGFβR2(-1) neoantigen-specific HLA-DR4-restricted T cell receptors for cancer therapy.

Journal for immunotherapy of cancer

Avec: Natalia Plewa , Lucia Poncette ,

HLA-C*04:09N is expressed at the cell surface and triggers peptide-specific T-cell activation.

Haematologica

Avec: Carlotta Welters , Marthe-Lina Welters , Serena Stadler , Lars Bullinger , Julian Strobel , Holger Hackstein , Arunraj Dhamodaran , Leo Hansmann

Réseau de co-auteurs

Gerald Willimsky 6 collaborations

Lars Bullinger 6 collaborations

Leo Hansmann 6 collaborations

Dieter Beule 5 collaborations

Carlotta Welters 4 collaborations

Kerstin Dietze 4 collaborations

Klaus Dornmair 4 collaborations

Antonia Busse 4 collaborations

Eric Blanc 4 collaborations

Holger Hackstein 4 collaborations

Lena Immisch 3 collaborations

George Papafotiou 3 collaborations

Vivian Scheuplein 3 collaborations

Livius Penter 3 collaborations

Andreas Moosmann 3 collaborations

Antonio Pezzutto 3 collaborations

Julian Strobel 3 collaborations

Lucia Poncette 3 collaborations

Thomas Kammertoens 3 collaborations

Oliver Popp 2 collaborations

Philipp Mertins 2 collaborations

María Fernanda Lammoglia Cobo 2 collaborations

Leonie Rosenberger 2 collaborations

Matthias Leisegang 2 collaborations

Thomas Kammertöns 2 collaborations

Armin Gerbitz 2 collaborations

Ulrich Keller 2 collaborations

Amin Ben Hamza 2 collaborations

Xiaojing Chen 2 collaborations

Serena Stadler 2 collaborations

Arunraj Dhamodaran 2 collaborations

Clemens Messerschmidt 2 collaborations

Sven Mahner 2 collaborations

Corinna Grunert 2 collaborations

Ana Textor 1 collaboration

Laura Grunewald 1 collaboration

Kathleen Anders 1 collaboration

Anika Klaus 1 collaboration

Silke Schwiebert 1 collaboration

Annika Winkler 1 collaboration

Maria Stecklum 1 collaboration

Jana Rolff 1 collaboration

Anton G Henssen 1 collaboration

Uta E Höpken 1 collaboration

Angelika Eggert 1 collaboration

Johannes H Schulte 1 collaboration

Michael C Jensen 1 collaboration

Annette Künkele 1 collaboration

Christin Beier 1 collaboration

Andrean Goede 1 collaboration

Hermann-Georg Holzhütter 1 collaboration

Peter M Kloetzel 1 collaboration

Christian Pircher 1 collaboration

Regina Gary 1 collaboration

Anna Takvorian 1 collaboration

Josefine Krüger 1 collaboration

Matthias Obenaus 1 collaboration

Igor Wolfgang Blau 1 collaboration

Dana Hoser 1 collaboration

Martin Vaegler 1 collaboration

Hana Rauschenbach 1 collaboration

Ioannis Anagnostopoulos 1 collaboration

Korinna Jöhrens 1 collaboration

Elisa Kieback 1 collaboration

Judith Böhme 1 collaboration

Ann-Christin Von Brünneck 1 collaboration

Jan Krönke 1 collaboration

Axel Nogai 1 collaboration

Christian Alexander Stein 1 collaboration

Meng-Tung Hsu 1 collaboration

Christopher Buccitelli 1 collaboration

Hans-Peter Rahn 1 collaboration

Monika Brüggemann 1 collaboration

Olaf Brauns 1 collaboration

Tim H Brümmendorf 1 collaboration

Thomas H Winkler 1 collaboration

Wolfgang Herr 1 collaboration

Fabian Beier 1 collaboration

Manuel Holtgrewe 1 collaboration

Tilman L R Vogelsang 1 collaboration

Elisa Schmoeckel 1 collaboration

Christina Kuhn 1 collaboration

Mina Temelkov 1 collaboration

Helene Heidegger 1 collaboration

Theresa Maria Kolben 1 collaboration

Thomas Kolben 1 collaboration

Doris Mayr 1 collaboration

Udo Jeschke 1 collaboration

Aurelia Vattai 1 collaboration

Julia Bluhm 1 collaboration

Stefanie Herda 1 collaboration

Andreas Heimann 1 collaboration

Benedikt Obermayer 1 collaboration

Elisa Ciraolo 1 collaboration

Stefanie Althoff 1 collaboration

Josefine Ruß 1 collaboration

Il-Kang Na 1 collaboration

Laure Garnier 1 collaboration

Robert Pick 1 collaboration

Julien Montorfani 1 collaboration

Mengzhu Sun 1 collaboration

Dale Brighouse 1 collaboration

Nicolas Liaudet 1 collaboration

Nicolas Page 1 collaboration

Jeremiah Bernier-Latamani 1 collaboration

Ngoc Lan Tran 1 collaboration

Tatiana V Petrova 1 collaboration

Doron Merkler 1 collaboration

Christoph Scheiermann 1 collaboration

Stéphanie Hugues 1 collaboration

Josephine Kemna 1 collaboration

Evelyne Gout 1 collaboration

Leon Daniau 1 collaboration

Jessica Lao 1 collaboration

Kristoffer Weißert 1 collaboration

Sandra Ammann 1 collaboration

Ralf Kühn 1 collaboration

Matthias Richter 1 collaboration

Christine Molenda 1 collaboration

Anje Sporbert 1 collaboration

Dario Zocholl 1 collaboration

Robert Klopfleisch 1 collaboration

Anja Schütz 1 collaboration

Hugues Lortat-Jacob 1 collaboration

Peter Aichele 1 collaboration

Laura Knop 1 collaboration

Charlotte Frommer 1 collaboration

Diana Stoycheva 1 collaboration

Katrin Deiser 1 collaboration

Ulrich Kalinke 1 collaboration

Ildiko Rita Dunay 1 collaboration

Thomas Schüler 1 collaboration

Felix Km Lorenz 1 collaboration

T Blankenstein 1 collaboration

A Grainger 1 collaboration

B Dube 1 collaboration

R Evans 1 collaboration

P Robinson 1 collaboration

Linn Woelber 1 collaboration

Katharina Prieske 1 collaboration

Christine Zu Eulenburg 1 collaboration

Stefanie Corradini 1 collaboration

Cordula Petersen 1 collaboration

Mareike Bommert 1 collaboration

Felix Hilpert 1 collaboration

Nikolaus de Gregorio 1 collaboration

Severine Iborra 1 collaboration

Jalid Sehouli 1 collaboration

Atanas Ignatov 1 collaboration

Peter Hillemanns 1 collaboration

Sophie Fuerst 1 collaboration

Hans-Georg Strauss 1 collaboration

Klaus Baumann 1 collaboration

Matthias W Beckmann 1 collaboration

Alexander Mustea 1 collaboration

Anna Jaeger 1 collaboration

Caroline Anna Peuker 1 collaboration

Simone Rhein 1 collaboration

Sara Caterina Maria O'Rourke 1 collaboration

Daniel Christmas 1 collaboration

Tom Blankenstein 1 collaboration

Julia Ritter 1 collaboration

Maria Fernanda Lammoglia Cobo 1 collaboration

Josefin Garmshausen 1 collaboration

Felix Aigner 1 collaboration

Sandra Wienzek-Lischka 1 collaboration

Michael Hummel 1 collaboration

Franziska Schumann 1 collaboration

Nerea Gallarín Delgado 1 collaboration

Annette Paschen 1 collaboration

Natalia Plewa 1 collaboration

Marthe-Lina Welters 1 collaboration