Takayuki Doi

Affiliations

Graduate School of Pharmaceutical Sciences, Tohoku University, 6-3 Aza-aoba, Aramaki, Aoba-ku, Sendai, 980-8578, Japan.

ORCID: http://orcid.org/0000-0002-8306-6819

Publications (25)

[Clinical Evaluation of the Efficacy and Adverse Effects of Nivolumab Treatment for Patients with Advanced Gastric Cancer].

Gan to kagaku ryoho. Cancer & chemotherapy

Avec: Atsuki Ohta , Shuhei Komatsu , Ryota Tsuji , Sachie Tanaka , Tatsuya Kumano , Kenichiro Imura , Katsumi Shimomura , Jun Ikeda , Fumihiro Taniguchi , Toshifumi Doi , Shinya Yamada , Naoya Tomatsuri , Norimasa Yoshida , Yasuhiro Shioaki

Scalable Total Syntheses and Structure-Activity Relationships of Haouamines A, B, and Their Derivatives as Stable Formate Salts.

Chemistry (Weinheim an der Bergstrasse, Germany)

Avec: Hirokazu Tsukamoto , Saki Nakamura , Akito Tomida ,

PRC2 Components Maintain DNA Hypermethylation of the Upstream Promoter and Regulate Robo4 Expression in Endothelial Cells.

Biological & pharmaceutical bulletin

Avec: Kohei Izawa , Keisuke Shirakura , Koji Kakiuchi , Nobuaki Funahashi , Naoki Maekawa , Nobumasa Hino , Toru Tanaka , Takefumi Doi , Yoshiaki Okada

Biomolecules

Avec: Chitose Maruyama , Yukiko Chinone , Shusuke Sato , Fumitaka Kudo , Kosuke Ohsawa , Junya Kubota , Junko Hashimoto , Ikuko Kozone , Kazuo Shin-Ya , Tadashi Eguchi , Yoshimitsu Hamano

The caudate nucleus contributes causally to decisions that balance reward and uncertain visual information.

eLife

Avec: Takahiro Doi , Yunshu Fan , Joshua I Gold , Long Ding

Recombinant thrombomodulin protects against LPS-induced acute respiratory distress syndrome via preservation of pulmonary endothelial glycocalyx.

British journal of pharmacology

Avec: Kodai Suzuki , Hideshi Okada , Genzou Takemura , Chihiro Takada , Hiroyuki Tomita , Hirohisa Yano , Isamu Muraki , Ryogen Zaikokuji , Ayumi Kuroda , Hirotsugu Fukuda , Ayane Nishio , Shigeo Takashima , Akio Suzuki , Nagisa Miyazaki , Tetsuya Fukuta , Noriaki Yamada , Takatomo Watanabe , Tomoaki Doi , Takahiro Yoshida , Keisuke Kumada , Hiroaki Ushikoshi , Shozo Yoshida , Shinji Ogura

A spontaneous middle ear adenocarcinoma characterized by abundant eosinophilic matrix in a young male Crl:CD(SD) rat.

Journal of toxicologic pathology

Avec: Hiroko Kokoshima , Naoaki Yamada , Yumi Wako , Takuya Doi , Minoru Tsuchitani

Model Informed Dosing Regimen and Phase I Results of the Anti-PD-1 Antibody Budigalimab (ABBV-181).

Clinical and translational science

Avec: John Powderly , Alexander Spira , Shunsuke Kondo , Toshihiko Doi , Jason J Luke , Drew Rasco , Bo Gao , Minna Tanner , Philippe A Cassier , Anas Gazzah , Antoine Italiano , Diego Tosi , Daniel E Afar , Apurvasena Parikh , Benjamin Engelhardt , Stefan Englert , Stacie L Lambert , Sreeneeranj Kasichayanula , Sven Mensing , Rajeev Menon , Gregory Vosganian , Anthony Tolcher

A single pretreatment with clofibric acid attenuates carbon tetrachloride-induced necrosis, but not steatosis, in rat liver.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association

Avec: Yoshihiro Yamakawa , Takaaki Doi , Yoshizumi Naitou , Hiroshi Kawai , Atsushi Mitsumoto , Naomi Kudo , Yoichi Kawashima

Effects of comorbid physical frailty and low muscle mass on incident disability in community-dwelling older adults: A 24-month follow-up longitudinal study.

Maturitas

Avec: Hideaki Ishii , Kota Tsutsumimoto , Takehiko Doi , Sho Nakakubo , Minji Kim , Satoshi Kurita , Hiroyuki Shimada

Transgenic animal models of congenital diaphragmatic hernia: a comprehensive overview of candidate genes and signaling pathways.

Pediatric surgery international

Avec: Hiroki Nakamura , Takashi Doi , Prem Puri , Florian Friedmacher

Neutrophil Elastase Inhibition Ameliorates Endotoxin-induced Myocardial Injury Accompanying Degradation of Cardiac Capillary Glycocalyx.

Shock (Augusta, Ga.)

Avec: Tetsuya Fukuta , Hideshi Okada , Genzou Takemura , Kodai Suzuki , Chihiro Takada , Hiroyuki Tomita , Akio Suzuki , Kazumasa Oda , Akihiro Uchida , Saori Matsuo , Hirotsugu Fukuda , Hirohisa Yano , Isamu Muraki , Ryogen Zaikokuji , Ayumi Kuroda , Ayane Nishio , So Sampei , Nagisa Miyazaki , Yasuaki Hotta , Noriaki Yamada , Takatomo Watanabe , Kentaro Morishita , Tomoaki Doi , Takahiro Yoshida , Hiroaki Ushikoshi , Shozo Yoshida , Yoichi Maekawa , Shinji Ogura

Positive effect of dapagliflozin on left ventricular longitudinal function for type 2 diabetic mellitus patients with chronic heart failure.

Cardiovascular diabetology

Avec: Hidekazu Tanaka , Fumitaka Soga , Kazuhiro Tatsumi , Yasuhide Mochizuki , Hiroyuki Sano , Hiromi Toki , Kensuke Matsumoto , Junya Shite , Hideyuki Takaoka , Tomofumi Doi , Ken-Ichi Hirata

[Analysis of the Environmental Factor of a Patient Falls in Department of Radiology-Proposal of Scientific Analysis Method in Patient Safety].

Nihon Hoshasen Gijutsu Gakkai zasshi

Avec: Tsukasa Doi , Makoto Nagayoshi , Yuya Yamatani , Eiji Yamada , Yoshihiro Matsuura , Tadashi Miyanishi , Masahiro Hashida

[The Actual Condition of Fall Accident and Suggestion of Improvement for Accident Prevention in the Department of Radiology].

Nihon Hoshasen Gijutsu Gakkai zasshi

Avec: Yuya Yamatani , Tsukasa Doi , Tadashi Miyanishi , Makoto Nagayoshi , Eiji Yamada , Yoshihiro Matsuura , Masahiro Hashida

Improvement of Blood Pressure Control by Adherence Check in Patients With Apparent Treatment-Resistant Hypertension: A Case Series.

Clinical medicine insights. Case reports

Avec: Keiko Hosohata , Ayaka Inada , Saki Oyama , Takashi Doi , Iku Niinomi , Tomohito Wakabayashi , Mayako Uchida , Kazunori Iwanaga , Hiroyuki Matsuoka

Imatinib in combination with phosphoinositol kinase inhibitor buparlisib in patients with gastrointestinal stromal tumour who failed prior therapy with imatinib and sunitinib: a Phase 1b, multicentre study.

British journal of cancer

Avec: Hans Gelderblom , Robin L Jones , Suzanne George , Claudia Valverde Morales , Charlotte Benson , Jean-Yves Blay , Daniel J Renouf , Toshihiko Doi , Axel Le Cesne , Michael Leahy , Sabine Hertle , Paola Aimone , Ulrike Brandt , Patrick Schӧffski

The Impact of Molecular Subtype on Efficacy of Chemotherapy and Checkpoint Inhibition in Advanced Gastric Cancer.

Clinical cancer research : an official journal of the American Association for Cancer Research

Avec: Yohei Kubota , Akihito Kawazoe , Akinori Sasaki , Saori Mishima , Kentaro Sawada , Yoshiaki Nakamura , Daisuke Kotani , Yasutoshi Kuboki , Hiroya Taniguchi , Takashi Kojima , Toshihiko Doi , Takayuki Yoshino , Genichiro Ishii , Takeshi Kuwata , Kohei Shitara

Enhanced tumor response to radiotherapy after PD-1 blockade in metastatic gastric cancer.

Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association

Avec: Akinori Sasaki , Yoshiaki Nakamura , Yosuke Togashi , Hirofumi Kuno , Hidehiro Hojo , Shunichiro Kageyama , Naoki Nakamura , Kenji Takashima , Tomohiro Kadota , Yusuke Yoda , Saori Mishima , Kentaro Sawada , Daisuke Kotani , Akihito Kawazoe , Yasutoshi Kuboki , Hiroya Taniguchi , Takashi Kojima , Toshihiko Doi , Takayuki Yoshino , Tomonori Yano , Tatsushi Kobayashi , Tetsuo Akimoto , Hiroyoshi Nishikawa , Kohei Shitara

Characterization and phase I study of CLR457, an orally bioavailable pan-class I PI3-kinase inhibitor.

Investigational new drugs

Avec: James J Harding , Todd M Bauer , Daniel S W Tan , Philippe L Bedard , Jordi Rodon , Toshihiko Doi , Christian Schnell , Varsha Iyer , Fabienne Baffert , Rajkumar Radhakrishnan , Claire Fabre , Dejan Juric

T-Cell-Inflamed Gene-Expression Profile, Programmed Death Ligand 1 Expression, and Tumor Mutational Burden Predict Efficacy in Patients Treated With Pembrolizumab Across 20 Cancers: KEYNOTE-028.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Avec: Patrick A Ott , Yung-Jue Bang , Sarina A Piha-Paul , Albiruni R Abdul Razak , Jaafar Bennouna , Jean-Charles Soria , Hope S Rugo , Roger B Cohen , Bert H O'Neil , Janice M Mehnert , Juanita Lopez , Toshihiko Doi , Emilie M J van Brummelen , Razvan Cristescu , Ping Yang , Kenneth Emancipator , Karen Stein , Mark Ayers , Andrew K Joe , Jared K Lunceford

Clinical significance of soluble forms of immune checkpoint molecules in advanced esophageal cancer.

Medical oncology (Northwood, London, England)

Avec: Juichiro Yoshida , Takeshi Ishikawa , Toshifumi Doi , Takayuki Ota , Tomoyo Yasuda , Tetsuya Okayama , Naoyuki Sakamoto , Ken Inoue , Osamu Dohi , Naohisa Yoshida , Kazuhiro Kamada , Kazuhiko Uchiyama , Tomohisa Takagi , Hideyuki Konishi , Yuji Naito , Yoshito Itoh

Development and validation of Comprehensive Gait Assessment using InerTial Sensor score (C-GAITS score) derived from acceleration and angular velocity data at heel and lower trunk among community-dwelling older adults.

Journal of neuroengineering and rehabilitation

Avec: Shogo Misu , Tsuyoshi Asai , Takehiko Doi , Ryuichi Sawa , Yuya Ueda , Shunsuke Murata , Takashi Saito , Taiki Sugimoto , Tsunenori Isa , Yamato Tsuboi , Minoru Yamada , Rei Ono

Effect of depression and anxiety on health-related quality of life outcomes and patient satisfaction after surgery for cervical compressive myelopathy.

Journal of neurosurgery. Spine

Avec: Toru Doi , Hideki Nakamoto , Koji Nakajima , Shima Hirai , Yusuke Sato , So Kato , Yuki Taniguchi , Yoshitaka Matsubayashi , Ko Matsudaira , Katsushi Takeshita , Sakae Tanaka , Yasushi Oshima

First-in-human phase 1 study of IT1208, a defucosylated humanized anti-CD4 depleting antibody, in patients with advanced solid tumors.

Journal for immunotherapy of cancer

Avec: Kohei Shitara , Satoshi Ueha , Shigeyuki Shichino , Hiroyasu Aoki , Haru Ogiwara , Tetsuya Nakatsura , Toshihiro Suzuki , Manami Shimomura , Toshiaki Yoshikawa , Kayoko Shoda , Shigehisa Kitano , Makiko Yamashita , Takayuki Nakayama , Akihiro Sato , Sakiko Kuroda , Masashi Wakabayashi , Shogo Nomura , Shoji Yokochi , Satoru Ito , Kouji Matsushima , Toshihiko Doi

Réseau de co-auteurs

Toshihiko Doi 7 collaborations

Kohei Shitara 3 collaborations

Toshifumi Doi 2 collaborations

Kodai Suzuki 2 collaborations

Hideshi Okada 2 collaborations

Genzou Takemura 2 collaborations

Chihiro Takada 2 collaborations

Hiroyuki Tomita 2 collaborations

Hirohisa Yano 2 collaborations

Isamu Muraki 2 collaborations

Ryogen Zaikokuji 2 collaborations

Ayumi Kuroda 2 collaborations

Hirotsugu Fukuda 2 collaborations

Ayane Nishio 2 collaborations

Akio Suzuki 2 collaborations

Nagisa Miyazaki 2 collaborations

Tetsuya Fukuta 2 collaborations

Noriaki Yamada 2 collaborations

Takatomo Watanabe 2 collaborations

Tomoaki Doi 2 collaborations

Takahiro Yoshida 2 collaborations

Hiroaki Ushikoshi 2 collaborations

Shozo Yoshida 2 collaborations

Shinji Ogura 2 collaborations

Takehiko Doi 2 collaborations

Takashi Doi 2 collaborations

Tsukasa Doi 2 collaborations

Makoto Nagayoshi 2 collaborations

Yuya Yamatani 2 collaborations

Eiji Yamada 2 collaborations

Yoshihiro Matsuura 2 collaborations

Tadashi Miyanishi 2 collaborations

Masahiro Hashida 2 collaborations

Akihito Kawazoe 2 collaborations

Akinori Sasaki 2 collaborations

Saori Mishima 2 collaborations

Kentaro Sawada 2 collaborations

Yoshiaki Nakamura 2 collaborations

Daisuke Kotani 2 collaborations

Yasutoshi Kuboki 2 collaborations

Hiroya Taniguchi 2 collaborations

Takashi Kojima 2 collaborations

Takayuki Yoshino 2 collaborations

Atsuki Ohta 1 collaboration

Shuhei Komatsu 1 collaboration

Ryota Tsuji 1 collaboration

Sachie Tanaka 1 collaboration

Tatsuya Kumano 1 collaboration

Kenichiro Imura 1 collaboration

Katsumi Shimomura 1 collaboration

Jun Ikeda 1 collaboration

Fumihiro Taniguchi 1 collaboration

Shinya Yamada 1 collaboration

Naoya Tomatsuri 1 collaboration

Norimasa Yoshida 1 collaboration

Yasuhiro Shioaki 1 collaboration

Hirokazu Tsukamoto 1 collaboration

Saki Nakamura 1 collaboration

Akito Tomida 1 collaboration

Kohei Izawa 1 collaboration

Keisuke Shirakura 1 collaboration

Koji Kakiuchi 1 collaboration

Nobuaki Funahashi 1 collaboration

Naoki Maekawa 1 collaboration

Nobumasa Hino 1 collaboration

Toru Tanaka 1 collaboration

Takefumi Doi 1 collaboration

Yoshiaki Okada 1 collaboration

Chitose Maruyama 1 collaboration

Yukiko Chinone 1 collaboration

Shusuke Sato 1 collaboration

Fumitaka Kudo 1 collaboration

Kosuke Ohsawa 1 collaboration

Junya Kubota 1 collaboration

Junko Hashimoto 1 collaboration

Ikuko Kozone 1 collaboration

Kazuo Shin-Ya 1 collaboration

Tadashi Eguchi 1 collaboration

Yoshimitsu Hamano 1 collaboration

Takahiro Doi 1 collaboration

Yunshu Fan 1 collaboration

Joshua I Gold 1 collaboration

Long Ding 1 collaboration

Shigeo Takashima 1 collaboration

Keisuke Kumada 1 collaboration

Hiroko Kokoshima 1 collaboration

Naoaki Yamada 1 collaboration

Yumi Wako 1 collaboration

Takuya Doi 1 collaboration

Minoru Tsuchitani 1 collaboration

John Powderly 1 collaboration

Alexander Spira 1 collaboration

Shunsuke Kondo 1 collaboration

Jason J Luke 1 collaboration

Drew Rasco 1 collaboration

Bo Gao 1 collaboration

Minna Tanner 1 collaboration

Philippe A Cassier 1 collaboration

Anas Gazzah 1 collaboration

Antoine Italiano 1 collaboration

Diego Tosi 1 collaboration

Daniel E Afar 1 collaboration

Apurvasena Parikh 1 collaboration

Benjamin Engelhardt 1 collaboration

Stefan Englert 1 collaboration

Stacie L Lambert 1 collaboration

Sreeneeranj Kasichayanula 1 collaboration

Sven Mensing 1 collaboration

Rajeev Menon 1 collaboration

Gregory Vosganian 1 collaboration

Anthony Tolcher 1 collaboration

Yoshihiro Yamakawa 1 collaboration

Takaaki Doi 1 collaboration

Yoshizumi Naitou 1 collaboration

Hiroshi Kawai 1 collaboration

Atsushi Mitsumoto 1 collaboration

Naomi Kudo 1 collaboration

Yoichi Kawashima 1 collaboration

Hideaki Ishii 1 collaboration

Kota Tsutsumimoto 1 collaboration

Sho Nakakubo 1 collaboration

Minji Kim 1 collaboration

Satoshi Kurita 1 collaboration

Hiroyuki Shimada 1 collaboration

Hiroki Nakamura 1 collaboration

Prem Puri 1 collaboration

Florian Friedmacher 1 collaboration

Kazumasa Oda 1 collaboration

Akihiro Uchida 1 collaboration

Saori Matsuo 1 collaboration

So Sampei 1 collaboration

Yasuaki Hotta 1 collaboration

Kentaro Morishita 1 collaboration

Yoichi Maekawa 1 collaboration

Hidekazu Tanaka 1 collaboration

Fumitaka Soga 1 collaboration

Kazuhiro Tatsumi 1 collaboration

Yasuhide Mochizuki 1 collaboration

Hiroyuki Sano 1 collaboration

Hiromi Toki 1 collaboration

Kensuke Matsumoto 1 collaboration

Junya Shite 1 collaboration

Hideyuki Takaoka 1 collaboration

Tomofumi Doi 1 collaboration

Ken-Ichi Hirata 1 collaboration

Keiko Hosohata 1 collaboration

Ayaka Inada 1 collaboration

Saki Oyama 1 collaboration

Iku Niinomi 1 collaboration

Tomohito Wakabayashi 1 collaboration

Mayako Uchida 1 collaboration

Kazunori Iwanaga 1 collaboration

Hiroyuki Matsuoka 1 collaboration

Hans Gelderblom 1 collaboration

Robin L Jones 1 collaboration

Suzanne George 1 collaboration

Claudia Valverde Morales 1 collaboration

Charlotte Benson 1 collaboration

None Jean-Yves Blay 1 collaboration

Daniel J Renouf 1 collaboration

Axel Le Cesne 1 collaboration

Michael Leahy 1 collaboration

Sabine Hertle 1 collaboration

Paola Aimone 1 collaboration

Ulrike Brandt 1 collaboration

Patrick Schӧffski 1 collaboration

Yohei Kubota 1 collaboration

Genichiro Ishii 1 collaboration

Takeshi Kuwata 1 collaboration

Yosuke Togashi 1 collaboration

Hirofumi Kuno 1 collaboration

Hidehiro Hojo 1 collaboration

Shunichiro Kageyama 1 collaboration

Naoki Nakamura 1 collaboration

Kenji Takashima 1 collaboration

Tomohiro Kadota 1 collaboration

Yusuke Yoda 1 collaboration

Tomonori Yano 1 collaboration

Tatsushi Kobayashi 1 collaboration

Tetsuo Akimoto 1 collaboration

Hiroyoshi Nishikawa 1 collaboration

James J Harding 1 collaboration

Todd M Bauer 1 collaboration

Daniel S W Tan 1 collaboration

Philippe L Bedard 1 collaboration

Jordi Rodon 1 collaboration

Christian Schnell 1 collaboration

Varsha Iyer 1 collaboration

Fabienne Baffert 1 collaboration

Rajkumar Radhakrishnan 1 collaboration

Claire Fabre 1 collaboration

Dejan Juric 1 collaboration

Patrick A Ott 1 collaboration

Yung-Jue Bang 1 collaboration

Sarina A Piha-Paul 1 collaboration

Albiruni R Abdul Razak 1 collaboration

Jaafar Bennouna 1 collaboration

Jean-Charles Soria 1 collaboration

Hope S Rugo 1 collaboration

Roger B Cohen 1 collaboration

Bert H O'Neil 1 collaboration

Janice M Mehnert 1 collaboration

Juanita Lopez 1 collaboration

Emilie M J van Brummelen 1 collaboration

Razvan Cristescu 1 collaboration

Ping Yang 1 collaboration

Kenneth Emancipator 1 collaboration

Karen Stein 1 collaboration

Mark Ayers 1 collaboration

Andrew K Joe 1 collaboration

Jared K Lunceford 1 collaboration

Juichiro Yoshida 1 collaboration

Takeshi Ishikawa 1 collaboration

Takayuki Ota 1 collaboration

Tomoyo Yasuda 1 collaboration

Tetsuya Okayama 1 collaboration

Naoyuki Sakamoto 1 collaboration

Ken Inoue 1 collaboration

Osamu Dohi 1 collaboration

Naohisa Yoshida 1 collaboration

Kazuhiro Kamada 1 collaboration

Kazuhiko Uchiyama 1 collaboration

Tomohisa Takagi 1 collaboration

Hideyuki Konishi 1 collaboration

Yuji Naito 1 collaboration

Yoshito Itoh 1 collaboration

Shogo Misu 1 collaboration

Tsuyoshi Asai 1 collaboration

Ryuichi Sawa 1 collaboration

Yuya Ueda 1 collaboration

Shunsuke Murata 1 collaboration

Takashi Saito 1 collaboration

Taiki Sugimoto 1 collaboration

Tsunenori Isa 1 collaboration

Yamato Tsuboi 1 collaboration

Minoru Yamada 1 collaboration

Rei Ono 1 collaboration

Toru Doi 1 collaboration

Hideki Nakamoto 1 collaboration

Koji Nakajima 1 collaboration

Shima Hirai 1 collaboration

Yusuke Sato 1 collaboration

So Kato 1 collaboration

Yuki Taniguchi 1 collaboration

Yoshitaka Matsubayashi 1 collaboration

Ko Matsudaira 1 collaboration

Katsushi Takeshita 1 collaboration

Sakae Tanaka 1 collaboration

Yasushi Oshima 1 collaboration

Satoshi Ueha 1 collaboration

Shigeyuki Shichino 1 collaboration

Hiroyasu Aoki 1 collaboration

Haru Ogiwara 1 collaboration

Tetsuya Nakatsura 1 collaboration

Toshihiro Suzuki 1 collaboration

Manami Shimomura 1 collaboration

Toshiaki Yoshikawa 1 collaboration

Kayoko Shoda 1 collaboration

Shigehisa Kitano 1 collaboration

Makiko Yamashita 1 collaboration

Takayuki Nakayama 1 collaboration

Akihiro Sato 1 collaboration

Sakiko Kuroda 1 collaboration

Masashi Wakabayashi 1 collaboration

Shogo Nomura 1 collaboration

Shoji Yokochi 1 collaboration

Satoru Ito 1 collaboration

Kouji Matsushima 1 collaboration