Stephanie Portelli

Affiliations

Systems and Computational Biology, Bio21 Institute, University of Melbourne, Melbourne, Victoria, Australia.
Computational Biology and Clinical Informatics, Baker Heart and Diabetes Institute, Melbourne, Victoria, Australia.

Publications (15)

Structure-guided machine learning prediction of drug resistance mutations in Abelson 1 kinase.

Computational and structural biotechnology journal

Avec: Yunzhuo Zhou , Megan Pat , Carlos H M Rodrigues , Thanh-Binh Nguyen , Douglas E V Pires , David B Ascher

Exploring the effects of missense mutations on protein thermodynamics through structure-based approaches: findings from the CAGI6 challenges.

Human genetics

Avec: Carlos H M Rodrigues , David B Ascher

Distinguishing between PTEN clinical phenotypes through mutation analysis.

Computational and structural biotechnology journal

Avec: Lucy Barr , Alex G C de Sá , Douglas E V Pires , David B Ascher

Definition of the immune evasion-replication interface of rabies virus P protein.

PLoS pathogens

Avec: Jingyu Zhan , Angela R Harrison , Thanh Binh Nguyen , Isshu Kojima , Siqiong Zheng , Fei Yan , Tatsunori Masatani , Stephen M Rawlinson , Ashish Sethi , Naoto Ito , David B Ascher , Gregory W Moseley , Paul R Gooley

AI-Driven Enhancements in Drug Screening and Optimization.

Methods in molecular biology (Clifton, N.J.)

Avec: Adam Serghini , David B Ascher

Computational saturation mutagenesis to predict structural consequences of systematic mutations in the beta subunit of RNA polymerase in

Computational and structural biotechnology journal

Avec: Sundeep Chaitanya Vedithi , Carlos H M Rodrigues , Marcin J Skwark , Madhusmita Das , David B Ascher , Tom L Blundell , Sony Malhotra

Prediction of rifampicin resistance beyond the RRDR using structure-based machine learning approaches.

Scientific reports

Avec: Yoochan Myung , Nicholas Furnham , Sundeep Chaitanya Vedithi , Douglas E V Pires , David B Ascher

toxCSM: comprehensive prediction of small molecule toxicity profiles.

Briefings in bioinformatics

Avec: Alex G C de Sá , Yangyang Long , Douglas E V Pires , David B Ascher

Laser Measurement and Numerical Simulation of Elastomer Stopper Motion during High-Altitude Shipping of Pharmaceutical Syringes.

PDA journal of pharmaceutical science and technology

Avec: Kirk Roffi , Naveed Siddiqui , Samantha Portelli , Divya Sharma , Jennifer Juneau , Parag Kolhe , Advait Badkar

Identifying Innate Resistance Hotspots for SARS-CoV-2 Antivirals Using In Silico Protein Techniques.

Genes

Avec: Ruby Heaton , David B Ascher

Exploring Protein Supersecondary Structure Through Changes in Protein Folding, Stability, and Flexibility.

Methods in molecular biology (Clifton, N.J.)

Avec: Douglas E V Pires , Carlos H M Rodrigues , Amanda T S Albanaz , Malancha Karmakar , Yoochan Myung , Joicymara Xavier , Eleni-Maria Michanetzi , David B Ascher

MTR3D-AF2: Expanding the coverage of spatially derived missense tolerance scores across the human proteome using AlphaFold2.

Protein science : a publication of the Protein Society

Avec: Aaron S Kovacs , Michael Silk , Carlos H M Rodrigues , David B Ascher

A metabolic signature for NADSYN1-dependent congenital NAD deficiency disorder.

The Journal of clinical investigation

Avec: Justin O Szot , Hartmut Cuny , Ella Mma Martin , Delicia Z Sheng , Kavitha Iyer , Vivien Nguyen , Jessica M Gereis , Dimuthu Alankarage , David Chitayat , Karen Chong , Ingrid M Wentzensen , Catherine Vincent-Delormé , Alban Lermine , Emma Burkitt-Wright , Weizhen Ji , Lauren Jeffries , Lynn S Pais , Tiong Y Tan , James Pitt , Cheryl A Wise , Helen Wright , Israel D Andrews , Brianna Pruniski , Theresa A Grebe , Nicole Corsten-Janssen , Katelijne Bouman , Cathryn Poulton , Supraja Prakash , Boris Keren , Natasha J Brown , Matthew F Hunter , Oliver Heath , Saquib A Lakhani , John H McDermott , David B Ascher , Gavin Chapman , Kayleigh Bozon , Sally L Dunwoodie

Characterization on the oncogenic effect of the missense mutations of p53 via machine learning.

Briefings in bioinformatics

Avec: Qisheng Pan , Thanh Binh Nguyen , David B Ascher

Rifaximin prophylaxis causes resistance to the last-resort antibiotic daptomycin.

Nature

Avec: Adrianna M Turner , Lucy Li , Ian R Monk , Jean Y H Lee , Danielle J Ingle , Norelle L Sherry , Nicole Isles , Torsten Seemann , Liam K Sharkey , Calum J Walsh , Gavin E Reid , Shuai Nie , Bart A Eijkelkamp , Natasha E Holmes , Brennan Collis , Sara Vogrin , Andreas Hiergeist , Daniela Weber , Andre Gessner , Ernst Holler , David B Ascher , Sebastian Duchene , Nichollas E Scott , Timothy P Stinear , Jason C Kwong , Claire L Gorrie , Benjamin P Howden , Glen P Carter

Réseau de co-auteurs

David B Ascher 14 collaborations

Carlos H M Rodrigues 5 collaborations

Douglas E V Pires 5 collaborations

Alex G C de Sá 2 collaborations

Thanh Binh Nguyen 2 collaborations

Sundeep Chaitanya Vedithi 2 collaborations

Yoochan Myung 2 collaborations

Yunzhuo Zhou 1 collaboration

Megan Pat 1 collaboration

Thanh-Binh Nguyen 1 collaboration

Lucy Barr 1 collaboration

Jingyu Zhan 1 collaboration

Angela R Harrison 1 collaboration

Isshu Kojima 1 collaboration

Siqiong Zheng 1 collaboration

Fei Yan 1 collaboration

Tatsunori Masatani 1 collaboration

Stephen M Rawlinson 1 collaboration

Ashish Sethi 1 collaboration

Naoto Ito 1 collaboration

Gregory W Moseley 1 collaboration

Paul R Gooley 1 collaboration

Adam Serghini 1 collaboration

Marcin J Skwark 1 collaboration

Madhusmita Das 1 collaboration

Tom L Blundell 1 collaboration

Sony Malhotra 1 collaboration

Nicholas Furnham 1 collaboration

Yangyang Long 1 collaboration

Kirk Roffi 1 collaboration

Naveed Siddiqui 1 collaboration

Samantha Portelli 1 collaboration

Divya Sharma 1 collaboration

Jennifer Juneau 1 collaboration

Parag Kolhe 1 collaboration

Advait Badkar 1 collaboration

Ruby Heaton 1 collaboration

Amanda T S Albanaz 1 collaboration

Malancha Karmakar 1 collaboration

Joicymara Xavier 1 collaboration

Eleni-Maria Michanetzi 1 collaboration

Aaron S Kovacs 1 collaboration

Michael Silk 1 collaboration

Justin O Szot 1 collaboration

Hartmut Cuny 1 collaboration

Ella Mma Martin 1 collaboration

Delicia Z Sheng 1 collaboration

Kavitha Iyer 1 collaboration

Vivien Nguyen 1 collaboration

Jessica M Gereis 1 collaboration

Dimuthu Alankarage 1 collaboration

David Chitayat 1 collaboration

Karen Chong 1 collaboration

Ingrid M Wentzensen 1 collaboration

Catherine Vincent-Delormé 1 collaboration

Alban Lermine 1 collaboration

Emma Burkitt-Wright 1 collaboration

Weizhen Ji 1 collaboration

Lauren Jeffries 1 collaboration

Lynn S Pais 1 collaboration

Tiong Y Tan 1 collaboration

James Pitt 1 collaboration

Cheryl A Wise 1 collaboration

Helen Wright 1 collaboration

Israel D Andrews 1 collaboration

Brianna Pruniski 1 collaboration

Theresa A Grebe 1 collaboration

Nicole Corsten-Janssen 1 collaboration

Katelijne Bouman 1 collaboration

Cathryn Poulton 1 collaboration

Supraja Prakash 1 collaboration

Boris Keren 1 collaboration

Natasha J Brown 1 collaboration

Matthew F Hunter 1 collaboration

Oliver Heath 1 collaboration

Saquib A Lakhani 1 collaboration

John H McDermott 1 collaboration

Gavin Chapman 1 collaboration

Kayleigh Bozon 1 collaboration

Sally L Dunwoodie 1 collaboration

Qisheng Pan 1 collaboration

Adrianna M Turner 1 collaboration

Lucy Li 1 collaboration

Ian R Monk 1 collaboration

Jean Y H Lee 1 collaboration

Danielle J Ingle 1 collaboration

Norelle L Sherry 1 collaboration

Nicole Isles 1 collaboration

Torsten Seemann 1 collaboration

Liam K Sharkey 1 collaboration

Calum J Walsh 1 collaboration

Gavin E Reid 1 collaboration

Shuai Nie 1 collaboration

Bart A Eijkelkamp 1 collaboration

Natasha E Holmes 1 collaboration

Brennan Collis 1 collaboration

Sara Vogrin 1 collaboration

Andreas Hiergeist 1 collaboration

Daniela Weber 1 collaboration

Andre Gessner 1 collaboration

Ernst Holler 1 collaboration

Sebastian Duchene 1 collaboration

Nichollas E Scott 1 collaboration

Timothy P Stinear 1 collaboration

Jason C Kwong 1 collaboration

Claire L Gorrie 1 collaboration

Benjamin P Howden 1 collaboration

Glen P Carter 1 collaboration