Simone D Scilabra

Affiliations

Fondazione Ri.MED, Department of Research, IRCCS-ISMETT, Palermo, Italy. sdscilabra@fondazionerimed.com.

Publications (23)

Strategies to Target ADAM17 in Disease: From its Discovery to the iRhom Revolution.

Molecules (Basel, Switzerland)

Avec: Matteo Calligaris , Doretta Cuffaro , Simone Bonelli , Donatella Pia Spanò , Armando Rossello , Elisa Nuti , Simone Dario Scilabra

Investigating the Differential Circulating microRNA Expression in Adolescent Females with Severe Idiopathic Scoliosis: A Proof-of-Concept Observational Clinical Study.

International journal of molecular sciences

Avec: Lavinia Raimondi , Angela De Luca , Alessia Gallo , Fabrizio Perna , Nicola Cuscino , Aurora Cordaro , Viviana Costa , Daniele Bellavia , Cesare Faldini , Simone Dario Scilabra , Gianluca Giavaresi , Angelo Toscano

Quantitative Mass Spectrometry-Based Secretome Analysis as a Tool to Investigate Metalloprotease and TIMP Activity.

Methods in molecular biology (Clifton, N.J.)

Avec: Chun-Yao Yang , Linda Troeberg ,

A top-down approach to uncover the hidden ligandome of low-density lipoprotein receptor-related protein 1 in cartilage.

Matrix biology : journal of the International Society for Matrix Biology

Avec: Kazuhiro Yamamoto , Carsten Scavenius , Maria M Meschis , Abdulrahman M E Gremida , Emilie H Mogensen , Ida B Thøgersen , Simone Bonelli , Anders Jensen , Salvatore Santamaria , Josefin Ahnström , George Bou-Gharios , Jan J Enghild , Hideaki Nagase

iRhom2 regulates ectodomain shedding and surface expression of the major histocompatibility complex (MHC) class I.

Cellular and molecular life sciences : CMLS

Avec: Matteo Calligaris , Donatella P Spanò , Simone Bonelli , Stephan A Müller , Claudia Carcione , Danilo D'apolito , Giandomenico Amico , Monica Miele , Mariangela Di Bella , Giovanni Zito , Elisa Nuti , Armando Rossello , Carl P Blobel , Stefan F Lichtenthaler ,

Functions of 'A disintegrin and metalloproteases (ADAMs)' in the mammalian nervous system.

Cellular and molecular life sciences : CMLS

Avec: Hung-En Hsia , Johanna Tüshaus , Tobias Brummer , Yuanpeng Zheng , Stefan F Lichtenthaler

An In Vitro Model of Glioma Development.

Genes

Avec: Gabriella Schiera , Patrizia Cancemi , Carlo Maria Di Liegro , Flores Naselli , Sara Volpes , Ilenia Cruciata , Paola Sofia Cardinale , Fabiola Vaglica , Matteo Calligaris , Anna Paola Carreca , Roberto Chiarelli , Simone Dario Scilabra , Olga Leone , Fabio Caradonna , Italia Di Liegro

Proteomic analysis and functional validation reveal distinct therapeutic capabilities related to priming of mesenchymal stromal/stem cells with IFN-γ and hypoxia: potential implications for their clinical use.

Frontiers in cell and developmental biology

Avec: Matteo Calligaris , Giovanni Zito , Rosalia Busà , Matteo Bulati , Gioacchin Iannolo , Alessia Gallo , Anna Paola Carreca , Nicola Cuscino , Salvatore Castelbuono , Claudia Carcione , Claudio Centi , Giandomenico Amico , Alessandro Bertani , Cinzia Maria Chinnici , Pier Giulio Conaldi , Simone Dario Scilabra , Vitale Miceli

Development of a Proteomic Workflow for the Identification of Heparan Sulphate Proteoglycan-Binding Substrates of ADAM17.

Proteomics

Avec: Matteo Calligaris , Donatella Pia Spanò , Maria Chiara Puccio , Stephan A Müller , Simone Bonelli , Margot Lo Pinto , Giovanni Zito , Carl P Blobel , Stefan F Lichtenthaler , Linda Troeberg , Simone Dario Scilabra

TIMP-3 facilitates binding of target metalloproteinases to the endocytic receptor LRP-1 and promotes scavenging of MMP-1.

Scientific reports

Avec: Anna P Carreca , Veronica M Pravatà , Matthew Markham , Simone Bonelli , Gillian Murphy , Hideaki Nagase , Linda Troeberg ,

Interleukin 13 (IL-13)-regulated expression of the chondroprotective metalloproteinase ADAM15 is reduced in aging cartilage.

Osteoarthritis and cartilage open

Avec: C Y Yang , A Chanalaris , S Bonelli , O McClurg , G Lorenzatti Hiles , A L Cates , J Miotla Zarebska , T L Vincent , M L Day , S A Müller , S F Lichtenthaler , H Nagase , S D Scilabra , L Troeberg

Tissue Inhibitor of Metalloproteases 3 (TIMP-3): In Vivo Analysis Underpins Its Role as a Master Regulator of Ectodomain Shedding.

Membranes

Avec: Donatella Pia Spanò , Simone Dario Scilabra

Quantitative Proteomics Reveals That ADAM15 Can Have Proteolytic-Independent Functions in the Steady State.

Membranes

Avec: Chun-Yao Yang , Simone Bonelli , Matteo Calligaris , Anna Paola Carreca , Stephan A Müller , Stefan F Lichtenthaler , Linda Troeberg ,

Human Amniotic MSC Response in LPS-Stimulated Ascites from Patients with Cirrhosis: FOXO1 Gene and Th17 Activation in Enhanced Antibacterial Activation.

International journal of molecular sciences

Avec: Mariangela Pampalone , Nicola Cuscino , Gioacchin Iannolo , Giandomenico Amico , Camillo Ricordi , Giampiero Vitale , Claudia Carcione , Salvatore Castelbuono , Simone Dario Scilabra , Claudia Coronnello , Salvatore Gruttadauria , Giada Pietrosi

Novel insights into the multifaceted and tissue-specific roles of the endocytic receptor LRP1.

The Journal of biological chemistry

Avec: Kazuhiro Yamamoto , Simone Bonelli , Anders Jensen , Carsten Scavenius , Jan J Enghild , Dudley K Strickland

Quantitative Proteomics Reveals Changes Induced by TIMP-3 on Cell Membrane Composition and Novel Metalloprotease Substrates.

International journal of molecular sciences

Avec: Anna Paola Carreca , Veronica Maria Pravatà , Danilo D'Apolito , Simone Bonelli , Matteo Calligaris , Elisa Monaca , Stephan A Müller , Stefan F Lichtenthaler , Simone Dario Scilabra

Topical application of a hyaluronic acid-based hydrogel integrated with secretome of human mesenchymal stromal cells for diabetic ulcer repair.

Regenerative therapy

Avec: Fabio Salvatore Palumbo , Matteo Calligaris , Laura Calzà , Calogero Fiorica , Vito Antonio Baldassarro , Anna Paola Carreca , Luca Lorenzini , Alessandro Giuliani , Claudia Carcione , Nicola Cuscino , Giovanna Pitarresi , Simone Dario Scilabra , Pier Giulio Conaldi , Cinzia Maria Chinnici

High-Resolution Secretome Analysis of Chemical Hypoxia Treated Cells Identifies Putative Biomarkers of Chondrosarcoma.

Proteomes

Avec: Donatella Pia Spanò , Simone Bonelli , Matteo Calligaris , Anna Paola Carreca , Claudia Carcione , Giovanni Zito , Aldo Nicosia , Sergio Rizzo , Simone Dario Scilabra

High-resolution proteomics and machine-learning identify protein classifiers of honey made by Sicilian black honeybees (Apis mellifera ssp. sicula).

Food research international (Ottawa, Ont.)

Avec: Giulia Biundo , Matteo Calligaris , Margot Lo Pinto , Danilo D'apolito , Salvatore Pasqua , Giulio Vitale , Giuseppe Gallo , Antonio Palumbo Piccionello ,

The Repertoire of Tissue Inhibitors of Metalloproteases: Evolution, Regulation of Extracellular Matrix Proteolysis, Engineering and Therapeutic Challenges.

Life (Basel, Switzerland)

Avec: Salvatore Costa , Maria Antonietta Ragusa , Gabriele Lo Buglio , Simone Dario Scilabra , Aldo Nicosia

Identification of membrane proteins regulated by ADAM15 by SUSPECS proteomics.

Frontiers in molecular biosciences

Avec: Matteo Calligaris , Chun Y Yang , Simone Bonelli , Donatella Pia Spanò , Stephan A Müller , Stefan F Lichtenthaler , Linda Troeberg ,

Proof-of-Concept Study on the Use of Tangerine-Derived Nanovesicles as siRNA Delivery Vehicles toward Colorectal Cancer Cell Line SW480.

International journal of molecular sciences

Avec: Nima Rabienezhad Ganji , Ornella Urzì , Vincenza Tinnirello , Elisa Costanzo , Giulia Polito , Antonio Palumbo Piccionello , Mauro Manno , Samuele Raccosta , Alessia Gallo , Margot Lo Pinto , Matteo Calligaris , Simone Dario Scilabra , Maria Antonietta Di Bella , Alice Conigliaro , Simona Fontana , Stefania Raimondo , Riccardo Alessandro

Proteomic characterization of ubiquitin carboxyl-terminal hydrolase 19 deficient cells reveals a role for USP19 in secretion of lysosomal proteins.

Molecular & cellular proteomics : MCP

Avec: Simone Bonelli , Margot Lo Pinto , Yihong Ye , Stephan A Mueller , Stefan F Lichtenthaler ,

Réseau de co-auteurs

Matteo Calligaris 12 collaborations

Simone Dario Scilabra 12 collaborations

Simone Bonelli 11 collaborations

Stefan F Lichtenthaler 7 collaborations

Anna Paola Carreca 6 collaborations

Donatella Pia Spanò 5 collaborations

Linda Troeberg 5 collaborations

Stephan A Müller 5 collaborations

Claudia Carcione 5 collaborations

Nicola Cuscino 4 collaborations

Giovanni Zito 4 collaborations

Margot Lo Pinto 4 collaborations

Alessia Gallo 3 collaborations

Giandomenico Amico 3 collaborations

Armando Rossello 2 collaborations

Elisa Nuti 2 collaborations

Chun-Yao Yang 2 collaborations

Kazuhiro Yamamoto 2 collaborations

Carsten Scavenius 2 collaborations

Anders Jensen 2 collaborations

Jan J Enghild 2 collaborations

Hideaki Nagase 2 collaborations

Danilo D'apolito 2 collaborations

Carl P Blobel 2 collaborations

Gioacchin Iannolo 2 collaborations

Salvatore Castelbuono 2 collaborations

Cinzia Maria Chinnici 2 collaborations

Pier Giulio Conaldi 2 collaborations

Aldo Nicosia 2 collaborations

Antonio Palumbo Piccionello 2 collaborations

Doretta Cuffaro 1 collaboration

Lavinia Raimondi 1 collaboration

Angela De Luca 1 collaboration

Fabrizio Perna 1 collaboration

Aurora Cordaro 1 collaboration

Viviana Costa 1 collaboration

Daniele Bellavia 1 collaboration

Cesare Faldini 1 collaboration

Gianluca Giavaresi 1 collaboration

Angelo Toscano 1 collaboration

Maria M Meschis 1 collaboration

Abdulrahman M E Gremida 1 collaboration

Emilie H Mogensen 1 collaboration

Ida B Thøgersen 1 collaboration

Salvatore Santamaria 1 collaboration

Josefin Ahnström 1 collaboration

George Bou-Gharios 1 collaboration

Donatella P Spanò 1 collaboration

Monica Miele 1 collaboration

Mariangela Di Bella 1 collaboration

Hung-En Hsia 1 collaboration

Johanna Tüshaus 1 collaboration

Tobias Brummer 1 collaboration

Yuanpeng Zheng 1 collaboration

Gabriella Schiera 1 collaboration

Patrizia Cancemi 1 collaboration

Carlo Maria Di Liegro 1 collaboration

Flores Naselli 1 collaboration

Sara Volpes 1 collaboration

Ilenia Cruciata 1 collaboration

Paola Sofia Cardinale 1 collaboration

Fabiola Vaglica 1 collaboration

Roberto Chiarelli 1 collaboration

Olga Leone 1 collaboration

Fabio Caradonna 1 collaboration

Italia Di Liegro 1 collaboration

Rosalia Busà 1 collaboration

Matteo Bulati 1 collaboration

Claudio Centi 1 collaboration

Alessandro Bertani 1 collaboration

Vitale Miceli 1 collaboration

Maria Chiara Puccio 1 collaboration

Anna P Carreca 1 collaboration

Veronica M Pravatà 1 collaboration

Matthew Markham 1 collaboration

Gillian Murphy 1 collaboration

C Y Yang 1 collaboration

A Chanalaris 1 collaboration

S Bonelli 1 collaboration

O McClurg 1 collaboration

G Lorenzatti Hiles 1 collaboration

A L Cates 1 collaboration

J Miotla Zarebska 1 collaboration

T L Vincent 1 collaboration

M L Day 1 collaboration

S A Müller 1 collaboration

S F Lichtenthaler 1 collaboration

H Nagase 1 collaboration

S D Scilabra 1 collaboration

L Troeberg 1 collaboration

Mariangela Pampalone 1 collaboration

Camillo Ricordi 1 collaboration

Giampiero Vitale 1 collaboration

Claudia Coronnello 1 collaboration

Salvatore Gruttadauria 1 collaboration

Giada Pietrosi 1 collaboration

Dudley K Strickland 1 collaboration

Veronica Maria Pravatà 1 collaboration

Danilo D'Apolito 1 collaboration

Elisa Monaca 1 collaboration

Fabio Salvatore Palumbo 1 collaboration

Laura Calzà 1 collaboration

Calogero Fiorica 1 collaboration

Vito Antonio Baldassarro 1 collaboration

Luca Lorenzini 1 collaboration

Alessandro Giuliani 1 collaboration

Giovanna Pitarresi 1 collaboration

Sergio Rizzo 1 collaboration

Giulia Biundo 1 collaboration

Salvatore Pasqua 1 collaboration

Giulio Vitale 1 collaboration

Giuseppe Gallo 1 collaboration

Salvatore Costa 1 collaboration

Maria Antonietta Ragusa 1 collaboration

Gabriele Lo Buglio 1 collaboration

Chun Y Yang 1 collaboration

Nima Rabienezhad Ganji 1 collaboration

Ornella Urzì 1 collaboration

Vincenza Tinnirello 1 collaboration

Elisa Costanzo 1 collaboration

Giulia Polito 1 collaboration

Mauro Manno 1 collaboration

Samuele Raccosta 1 collaboration

Maria Antonietta Di Bella 1 collaboration

Alice Conigliaro 1 collaboration

Simona Fontana 1 collaboration

Stefania Raimondo 1 collaboration

Riccardo Alessandro 1 collaboration

Yihong Ye 1 collaboration

Stephan A Mueller 1 collaboration