Silvana Zanlungo

Affiliations

Department of Gastroenterology, Faculty of Medicine, Pontificia Universidad Católica de Chile, Av. Libertador Bernardo O'Higgins 340, Santiago 8331150, Chile.

Publications (20)

c-Abl Phosphorylates MFN2 to Regulate Mitochondrial Morphology in Cells under Endoplasmic Reticulum and Oxidative Stress, Impacting Cell Survival and Neurodegeneration.

Antioxidants (Basel, Switzerland)

Avec: Alexis Martinez , Cristian M Lamaizon , Cristian Valls , Fabien Llambi , Nancy Leal , Patrick Fitzgerald , Cliff Guy , Marcin M Kamiński , Nibaldo C Inestrosa , Brigitte van Zundert , Gonzalo I Cancino , Andrés E Dulcey , Juan J Marugan , Claudio Hetz , Douglas R Green , Alejandra R Alvarez

c-Abl Activation Linked to Autophagy-Lysosomal Dysfunction Contributes to Neurological Impairment in Niemann-Pick Type A Disease.

Frontiers in cell and developmental biology

Avec: Tamara Marín , Andrés E Dulcey , Fabián Campos , Catalina de la Fuente , Mariana Acuña , Juan Castro , Claudio Pinto , María José Yañez , Cristian Cortez , David W McGrath , Pablo J Sáez , Kirill Gorshkov , Wei Zheng , Noel Southall , Maria Carmo-Fonseca , Juan Marugán , Alejandra R Alvarez ,

Autophagy Induced by Toll-like Receptor Ligands Regulates Antigen Extraction and Presentation by B Cells.

Cells

Avec: Jonathan Lagos , Sara Sagadiev , Jheimmy Diaz , Juan Pablo Bozo , Fanny Guzman , Caroline Stefani , Mridu Acharya , Maria Isabel Yuseff

Exploring the lutein therapeutic potential in steatotic liver disease: mechanistic insights and future directions.

Frontiers in pharmacology

Avec: Elisa Balboa , Faride Saud , Claudia Parra-Ruiz , Marjorie de la Fuente , Glauben Landskron ,

Lysosome motility and distribution: Relevance in health and disease.

Biochimica et biophysica acta. Molecular basis of disease

Avec: Juan Esteban Oyarzún , Jonathan Lagos , Mary Carmen Vázquez , Cristian Valls , Catalina De la Fuente , María Isabel Yuseff , Alejandra R Alvarez ,

Genistein Activates Transcription Factor EB and Corrects Niemann-Pick C Phenotype.

International journal of molecular sciences

Avec: Graciela Argüello , Elisa Balboa , Pablo J Tapia , Juan Castro , María José Yañez , Pamela Mattar , Rodrigo Pulgar ,

Prophylactic treatment with the c-Abl inhibitor, neurotinib, diminishes neuronal damage and the convulsive state in pilocarpine-induced mice.

Cell reports

Avec: América Chandía-Cristi , Daniela A Gutiérrez , Andrés E Dulcey , Marcelo Lara , Lina Vargas , Yi-Han Lin , Pablo Jimenez-Muñoz , Gabriela Larenas , Xin Xu , Amy Wang , Ashley Owens , Christopher Dextras , YuChi Chen , Claudio Pinto , Tamara Marín , Hugo Almarza-Salazar , Keryma Acevedo , Gonzalo I Cancino , Xin Hu , Patricio Rojas , Marc Ferrer , Noel Southall , Mark J Henderson , Juan J Marugan , Alejandra Álvarez R

c-Abl kinase at the crossroads of healthy synaptic remodeling and synaptic dysfunction in neurodegenerative diseases.

Neural regeneration research

Avec: Daniela A Gutiérrez , América Chandía-Cristi , María José Yáñez , Alejandra R Álvarez

Finding pathogenic commonalities between Niemann-Pick type C and other lysosomal storage disorders: Opportunities for shared therapeutic interventions.

Biochimica et biophysica acta. Molecular basis of disease

Avec: M J Yañez , T Marín , E Balboa , A D Klein , A R Alvarez , S Zanlungo

Proteomic Analysis of Niemann-Pick Type C Hepatocytes Reveals Potential Therapeutic Targets for Liver Damage.

Cells

Avec: Elisa Balboa , Tamara Marín , Juan Esteban Oyarzún , Pablo S Contreras , Robert Hardt , Thea van den Bosch , Alejandra R Alvarez , Boris Rebolledo-Jaramillo , Andres D Klein , Dominic Winter ,

A Mouse Systems Genetics Approach Reveals Common and Uncommon Genetic Modifiers of Hepatic Lysosomal Enzyme Activities and Glycosphingolipids.

International journal of molecular sciences

Avec: Anyelo Durán , David A Priestman , Macarena Las Heras , Boris Rebolledo-Jaramillo , Valeria Olguín , Juan F Calderón , Jaime Gutiérrez , Frances M Platt , Andrés D Klein

c-Abl tyrosine kinase down-regulation as target for memory improvement in Alzheimer's disease.

Frontiers in aging neuroscience

Avec: Rilda León , Daniela A Gutiérrez , Claudio Pinto , Cristian Morales , Catalina de la Fuente , Cristóbal Riquelme , Bastián I Cortés , Adrián González-Martin , David Chamorro , Nelson Espinosa , Pablo Fuentealba , Gonzalo I Cancino , Andrés E Dulcey , Juan J Marugan , Alejandra Álvarez Rojas

Understanding the phenotypic variability in Niemann-Pick disease type C (NPC): a need for precision medicine.

NPJ genomic medicine

Avec: Macarena Las Heras , Benjamín Szenfeld , Rami A Ballout , Emanuele Buratti , Andrea Dardis , Andrés D Klein

c-Abl Inhibition Activates TFEB and Promotes Cellular Clearance in a Lysosomal Disorder.

iScience

Avec: Pablo S Contreras , Pablo J Tapia , Lila González-Hódar , Ivana Peluso , Chiara Soldati , Gennaro Napolitano , Maria Matarese , Macarena Las Heras , Cristian Valls , Alexis Martinez , Elisa Balboa , Juan Castro , Nancy Leal , Frances M Platt , Andrzej Sobota , Dominic Winter , Andrés D Klein , Diego L Medina , Andrea Ballabio , Alejandra R Alvarez ,

c-Abl activates RIPK3 signaling in Gaucher disease.

Biochimica et biophysica acta. Molecular basis of disease

Avec: M J Yañez , F Campos , T Marín , A D Klein , A H Futerman , A R Alvarez , S Zanlungo

Lack of Annexin A6 Exacerbates Liver Dysfunction and Reduces Lifespan of Niemann-Pick Type C Protein-Deficient Mice.

The American journal of pathology

Avec: Elsa Meneses-Salas , Marta Garcia-Forn , Carla Castany-Pladevall , Albert Lu , Alba Fajardo , Jaimy Jose , Mohamed Wahba , Marta Bosch , Albert Pol , Francesc Tebar , Andrés D Klein , Esther Pérez-Navarro , Thomas Grewal , Carlos Enrich , Carles Rentero

Complement Component C3 Participates in Early Stages of Niemann-Pick C Mouse Liver Damage.

International journal of molecular sciences

Avec: Andrés D Klein , Javier González de la Vega ,

Identification of genetic modifiers of murine hepatic β-glucocerebrosidase activity.

Biochemistry and biophysics reports

Avec: Anyelo Durán , Boris Rebolledo-Jaramillo , Valeria Olguin , Marcelo Rojas-Herrera , Macarena Las Heras , Juan F Calderón , David A Priestman , Frances M Platt , Andrés D Klein

Alterations in Lysosome Homeostasis in Lipid-Related Disorders: Impact on Metabolic Tissues and Immune Cells.

Frontiers in cell and developmental biology

Avec: Fernanda Cabrera-Reyes , Claudia Parra-Ruiz , María Isabel Yuseff ,

Neuronopathic Gaucher disease: Beyond lysosomal dysfunction.

Frontiers in molecular neuroscience

Avec: Nohela B Arévalo , Cristian M Lamaizon , Viviana A Cavieres , Patricia V Burgos , Alejandra R Álvarez , María J Yañez ,

Réseau de co-auteurs

Andrés D Klein 6 collaborations

Alejandra R Alvarez 5 collaborations

Andrés E Dulcey 4 collaborations

Elisa Balboa 4 collaborations

Macarena Las Heras 4 collaborations

Cristian Valls 3 collaborations

Gonzalo I Cancino 3 collaborations

Juan J Marugan 3 collaborations

Tamara Marín 3 collaborations

Juan Castro 3 collaborations

Claudio Pinto 3 collaborations

Daniela A Gutiérrez 3 collaborations

Boris Rebolledo-Jaramillo 3 collaborations

Frances M Platt 3 collaborations

Alexis Martinez 2 collaborations

Cristian M Lamaizon 2 collaborations

Nancy Leal 2 collaborations

Catalina de la Fuente 2 collaborations

María José Yañez 2 collaborations

Noel Southall 2 collaborations

Jonathan Lagos 2 collaborations

Claudia Parra-Ruiz 2 collaborations

Juan Esteban Oyarzún 2 collaborations

María Isabel Yuseff 2 collaborations

Pablo J Tapia 2 collaborations

América Chandía-Cristi 2 collaborations

Alejandra R Álvarez 2 collaborations

M J Yañez 2 collaborations

T Marín 2 collaborations

A D Klein 2 collaborations

A R Alvarez 2 collaborations

S Zanlungo 2 collaborations

Pablo S Contreras 2 collaborations

Dominic Winter 2 collaborations

Anyelo Durán 2 collaborations

David A Priestman 2 collaborations

Juan F Calderón 2 collaborations

Fabien Llambi 1 collaboration

Patrick Fitzgerald 1 collaboration

Cliff Guy 1 collaboration

Marcin M Kamiński 1 collaboration

Nibaldo C Inestrosa 1 collaboration

Brigitte van Zundert 1 collaboration

Claudio Hetz 1 collaboration

Douglas R Green 1 collaboration

Fabián Campos 1 collaboration

Mariana Acuña 1 collaboration

Cristian Cortez 1 collaboration

David W McGrath 1 collaboration

Pablo J Sáez 1 collaboration

Kirill Gorshkov 1 collaboration

Wei Zheng 1 collaboration

Maria Carmo-Fonseca 1 collaboration

Juan Marugán 1 collaboration

Sara Sagadiev 1 collaboration

Jheimmy Diaz 1 collaboration

Juan Pablo Bozo 1 collaboration

Fanny Guzman 1 collaboration

Caroline Stefani 1 collaboration

Mridu Acharya 1 collaboration

Maria Isabel Yuseff 1 collaboration

Faride Saud 1 collaboration

Marjorie de la Fuente 1 collaboration

Glauben Landskron 1 collaboration

Mary Carmen Vázquez 1 collaboration

Catalina De la Fuente 1 collaboration

Graciela Argüello 1 collaboration

Pamela Mattar 1 collaboration

Rodrigo Pulgar 1 collaboration

Marcelo Lara 1 collaboration

Lina Vargas 1 collaboration

Yi-Han Lin 1 collaboration

Pablo Jimenez-Muñoz 1 collaboration

Gabriela Larenas 1 collaboration

Xin Xu 1 collaboration

Amy Wang 1 collaboration

Ashley Owens 1 collaboration

Christopher Dextras 1 collaboration

YuChi Chen 1 collaboration

Hugo Almarza-Salazar 1 collaboration

Keryma Acevedo 1 collaboration

Xin Hu 1 collaboration

Patricio Rojas 1 collaboration

Marc Ferrer 1 collaboration

Mark J Henderson 1 collaboration

Alejandra Álvarez R 1 collaboration

María José Yáñez 1 collaboration

E Balboa 1 collaboration

Robert Hardt 1 collaboration

Thea van den Bosch 1 collaboration

Andres D Klein 1 collaboration

Valeria Olguín 1 collaboration

Jaime Gutiérrez 1 collaboration

Rilda León 1 collaboration

Cristian Morales 1 collaboration

Cristóbal Riquelme 1 collaboration

Bastián I Cortés 1 collaboration

Adrián González-Martin 1 collaboration

David Chamorro 1 collaboration

Nelson Espinosa 1 collaboration

Pablo Fuentealba 1 collaboration

Alejandra Álvarez Rojas 1 collaboration

Benjamín Szenfeld 1 collaboration

Rami A Ballout 1 collaboration

Emanuele Buratti 1 collaboration

Andrea Dardis 1 collaboration

Lila González-Hódar 1 collaboration

Ivana Peluso 1 collaboration

Chiara Soldati 1 collaboration

Gennaro Napolitano 1 collaboration

Maria Matarese 1 collaboration

Andrzej Sobota 1 collaboration

Diego L Medina 1 collaboration

Andrea Ballabio 1 collaboration

F Campos 1 collaboration

A H Futerman 1 collaboration

Elsa Meneses-Salas 1 collaboration

Marta Garcia-Forn 1 collaboration

Carla Castany-Pladevall 1 collaboration

Albert Lu 1 collaboration

Alba Fajardo 1 collaboration

Jaimy Jose 1 collaboration

Mohamed Wahba 1 collaboration

Marta Bosch 1 collaboration

Albert Pol 1 collaboration

Francesc Tebar 1 collaboration

Esther Pérez-Navarro 1 collaboration

Thomas Grewal 1 collaboration

Carlos Enrich 1 collaboration

Carles Rentero 1 collaboration

Javier González de la Vega 1 collaboration

Valeria Olguin 1 collaboration

Marcelo Rojas-Herrera 1 collaboration

Fernanda Cabrera-Reyes 1 collaboration

Nohela B Arévalo 1 collaboration

Viviana A Cavieres 1 collaboration

Patricia V Burgos 1 collaboration

María J Yañez 1 collaboration