Sarah Melov

Affiliations

Reproduction and Perinatal Centre, Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia.
Westmead Institute for Maternal & Fetal Medicine, Westmead Hospital, Westmead, New South Wales, Australia.

Publications (22)

Superoxide produced by mitochondrial site I

Free radical biology & medicine

Avec: Hoi-Shan Wong , Vojtech Mezera , Pratiksha Dighe , Simon Melov , Akos A Gerencser , Ramzi F Sweis , Marina Pliushchev , Zhi Wang , Tim Esbenshade , Bryan McKibben , Stephan Riedmaier , Martin D Brand

Aging impairs the osteocytic regulation of collagen integrity and bone quality.

Bone research

Avec: Charles A Schurman , Serra Kaya , Neha Dole , Nadja M Maldonado Luna , Natalia Castillo , Ryan Potter , Jacob P Rose , Joanna Bons , Christina D King , Jordan B Burton , Birgit Schilling , Simon Melov , Simon Tang , Eric Schaible , Tamara Alliston

Single-cell analysis identifies conserved features of immune dysfunction in simulated microgravity and spaceflight.

Nature communications

Avec: Fei Wu , Huixun Du , Eliah Overbey , JangKeun Kim , Priya Makhijani , Nicolas Martin , Chad A Lerner , Khiem Nguyen , Jordan Baechle , Taylor R Valentino , Matias Fuentealba , Juliet M Bartleson , Heather Halaweh , Shawn Winer , Cem Meydan , Francine Garrett-Bakelman , Nazish Sayed , Simon Melov , Masafumi Muratani , Akos A Gerencser , Herbert G Kasler , Afshin Beheshti , Christopher E Mason , David Furman , Daniel A Winer

Characterizing phenotypic data of Peromyscus leucopus compared to C57BL/6J Mus musculus and diversity outbred (DO) Mus musculus.

GeroScience

Avec: Lauren A Wimer , Asia Davis-Castillo , Sofiya Galkina , Serban Ciotlos , Cavan Patterson , Leandro Prado , Maria Castro Munoz , Nicolas Martin , Sharon Epstein , Nicholas Schaum , Simon Melov

Accelerated aging of the brain transcriptome by the common chemotherapeutic doxorubicin.

Experimental gerontology

Avec: Alyssa N Cavalier , Zachary S Clayton , David A Hutton , Devin Wahl , Daniel S Lark , Julie A Reisz , Simon Melov , Judith Campisi , Douglas R Seals , Thomas J LaRocca

Senolysis induced by 25-hydroxycholesterol targets CRYAB in multiple cell types.

iScience

Avec: Chandani Limbad , Ryosuke Doi , Julia McGirr , Serban Ciotlos , Kevin Perez , Zachary S Clayton , Radha Daya , Douglas R Seals , Judith Campisi , Simon Melov

Role of the Senescence-Associated Factor Dipeptidyl Peptidase 4 in the Pathogenesis of SARS-CoV-2 Infection.

Aging and disease

Avec: Stefanie Deinhardt-Emmer , Sharvari Deshpande , Koji Kitazawa , Allison B Herman , Joanna Bons , Jacob P Rose , Prasanna Ashok Kumar , Carlos Anerillas , Francesco Neri , Serban Ciotlos , Kevin Perez , Nilay Köse-Vogel , Antje Häder , Kotb Abdelmohsen , Bettina Löffler , Myriam Gorospe , Pierre-Yves Desprez , Simon Melov , David Furman , Birgit Schilling , Judith Campisi

Pregnancy outcomes in women with gestational diabetes mellitus by models of care: a retrospective cohort study.

BMJ open

Avec: Jackson Harrison , Adrienne C Kirby , Neil Athayde , Araz Boghossian , Wah Cheung , Emma Inglis , Kavita Maravar , Suja Padmanabhan , Melissa Luig , Monica Hook , Dharmintra Pasupathy

Antiretroviral protease inhibitors induce features of cellular senescence that are reversible upon drug removal.

Aging cell

Avec: Chisaka Kuehnemann , Jun-Wei B Hughes , Pierre-Yves Desprez , Simon Melov , Christopher D Wiley , Judith Campisi

Cellular Senescence Contributes to Large Elastic Artery Stiffening and Endothelial Dysfunction With Aging: Amelioration With Senolytic Treatment.

Hypertension (Dallas, Tex. : 1979)

Avec: Zachary S Clayton , Matthew J Rossman , Sophia A Mahoney , Ravinandan Venkatasubramanian , Grace S Maurer , David A Hutton , Nicholas S VanDongen , Nathan T Greenberg , Abigail G Longtine , Katelyn R Ludwig , Vienna E Brunt , Thomas J LaRocca , Judith Campisi , Simon Melov , Douglas R Seals

Apigenin restores endothelial function by ameliorating oxidative stress, reverses aortic stiffening, and mitigates vascular inflammation with aging.

American journal of physiology. Heart and circulatory physiology

Avec: Zachary S Clayton , David A Hutton , Vienna E Brunt , Nicholas S VanDongen , Brian P Ziemba , Abigail G Casso , Nathan T Greenberg , Amanda N Mercer , Matthew J Rossman , Judith Campisi , Simon Melov , Douglas R Seals

Organ Mapping Antibody Panels: a community resource for standardized multiplexed tissue imaging.

Nature methods

Avec: Ellen M Quardokus , Diane C Saunders , Elizabeth McDonough , John W Hickey , Christopher Werlein , Christine Surrette , Presha Rajbhandari , Anna Martinez Casals , Hua Tian , Lisa Lowery , Elizabeth K Neumann , Frida Björklund , Taruna V Neelakantan , Josh Croteau , Anne E Wiblin , Jeremy Fisher , April J Livengood , Karen G Dowell , Jonathan C Silverstein , Jeffrey M Spraggins , Gloria S Pryhuber , Gail Deutsch , Fiona Ginty , Garry P Nolan , Simon Melov , Danny Jonigk , Michael A Caldwell , Ioannis S Vlachos , Werner Muller , Nils Gehlenborg , Brent R Stockwell , Emma Lundberg , Michael P Snyder , Ronald N Germain , Jeannie M Camarillo , Neil L Kelleher , Katy Börner , Andrea J Radtke

Intermittent supplementation with fisetin improves arterial function in old mice by decreasing cellular senescence.

Aging cell

Avec: Sophia A Mahoney , Ravinandan Venkatasubramanian , Mary A Darrah , Katelyn R Ludwig , Nicholas S VanDongen , Nathan T Greenberg , Abigail G Longtine , David A Hutton , Vienna E Brunt , Judith Campisi , Simon Melov , Douglas R Seals , Matthew J Rossman , Zachary S Clayton

From discoveries in ageing research to therapeutics for healthy ageing.

Nature

Avec: Judith Campisi , Pankaj Kapahi , Gordon J Lithgow , Simon Melov , John C Newman , Eric Verdin

Tumor Necrosis Factor Alpha-Mediated Inflammation and Remodeling of the Extracellular Matrix Underlies Aortic Stiffening Induced by the Common Chemotherapeutic Agent Doxorubicin.

Hypertension (Dallas, Tex. : 1979)

Avec: Zachary S Clayton , Vienna E Brunt , David A Hutton , Abigail G Casso , Brian P Ziemba , Simon Melov , Judith Campisi , Douglas R Seals

Effectiveness of a customised mobile phone text messaging intervention supported by data from activity monitors for improving lifestyle factors related to the risk of type 2 diabetes among women after gestational diabetes: protocol for a multicentre randomised controlled trial (SMART MUMS with smart phones 2).

BMJ open

Avec: Simone Marschner , Clara Chow , Aravinda Thiagalingam , David Simmons , Mark McClean , Dharmintra Pasupathy , Ben J Smith , Victoria Flood , Suja Padmanabhan , Cellina Ching , N Wah Cheung

Senescent and disease-associated microglia are modifiable features of aged brain white matter.

Research square

Avec: Chase M Carver , Paul T Gomez , Sonia L Rodriguez , Jennifer M Kachergus , Yi Liu , Ji Shi , Tommy Tran , Liguo Wang , Simon Melov , E Aubrey Thompson , Marissa J Schafer

Single nuclei profiling identifies cell specific markers of skeletal muscle aging, frailty, and senescence.

Aging

Avec: Kevin Perez , Serban Ciotlos , Julia McGirr , Chandani Limbad , Ryosuke Doi , Joshua P Nederveen , Mats I Nilsson , Daniel A Winer , William Evans , Mark Tarnopolsky , Judith Campisi , Simon Melov

Longitudinal Functional Study of Murine Aging: A Resource for Future Study Designs.

JBMR plus

Avec: Daniel S Evans , Monique N O'Leary , Ryan Murphy , Minna Schmidt , Kristin Koenig , Michael Presley , Brittany Garrett , Ha-Neui Kim , Li Han , Emmeline C Academia , Matt J Laye , Daniel Edgar , Christopher A Zambataro , Tracey Barhydt , Colleen M Dewey , Jarrott Mayfield , Joy Wilson , Silvestre Alavez , Mark Lucanic , Brian K Kennedy , Maria Almeida , Julie K Andersen , Pankaj Kapahi , Gordon J Lithgow , Simon Melov

Dietary restriction and the transcription factor clock delay eye aging to extend lifespan in Drosophila Melanogaster.

Nature communications

Avec: Brian A Hodge , Geoffrey T Meyerhof , Subhash D Katewa , Ting Lian , Charles Lau , Sudipta Bar , Nicole Y Leung , Menglin Li , David Li-Kroeger , Simon Melov , Birgit Schilling , Craig Montell , Pankaj Kapahi

COVID-19 vaccine acceptance among pregnant women and the reasons for hesitancy: A multi-centre cross-sectional survey.

The Australian & New Zealand journal of obstetrics & gynaecology

Avec: Monica Rikard-Bell , James Elhindi , Justin Lam , Sean Seeho , Kirsten Black , Greg Jenkins , Justin McNab , Kerrie Wiley , Dharmintra Pasupathy

The D

Aging cell

Avec: Lauren Wimer , Elena Goncharova , Sofiya Galkina , Edna Nyangau , Mahalakshmi Shankaran , Asia Davis , Leandro Prado , Maria Castro Munoz , Sharon Epstein , Cavan Patterson , Nicholas Shaum , Mark Hellerstein , William Evans , Simon Melov

Réseau de co-auteurs

Simon Melov 19 collaborations

Judith Campisi 10 collaborations

Zachary S Clayton 6 collaborations

Douglas R Seals 6 collaborations

David A Hutton 5 collaborations

Serban Ciotlos 4 collaborations

Vienna E Brunt 4 collaborations

Birgit Schilling 3 collaborations

Kevin Perez 3 collaborations

Dharmintra Pasupathy 3 collaborations

Matthew J Rossman 3 collaborations

Nicholas S VanDongen 3 collaborations

Nathan T Greenberg 3 collaborations

Pankaj Kapahi 3 collaborations

Akos A Gerencser 2 collaborations

Jacob P Rose 2 collaborations

Joanna Bons 2 collaborations

Nicolas Martin 2 collaborations

David Furman 2 collaborations

Daniel A Winer 2 collaborations

Sofiya Galkina 2 collaborations

Cavan Patterson 2 collaborations

Leandro Prado 2 collaborations

Maria Castro Munoz 2 collaborations

Sharon Epstein 2 collaborations

Thomas J LaRocca 2 collaborations

Chandani Limbad 2 collaborations

Ryosuke Doi 2 collaborations

Julia McGirr 2 collaborations

Pierre-Yves Desprez 2 collaborations

Suja Padmanabhan 2 collaborations

Sophia A Mahoney 2 collaborations

Ravinandan Venkatasubramanian 2 collaborations

Abigail G Longtine 2 collaborations

Katelyn R Ludwig 2 collaborations

Brian P Ziemba 2 collaborations

Abigail G Casso 2 collaborations

Gordon J Lithgow 2 collaborations

William Evans 2 collaborations

Hoi-Shan Wong 1 collaboration

Vojtech Mezera 1 collaboration

Pratiksha Dighe 1 collaboration

Ramzi F Sweis 1 collaboration

Marina Pliushchev 1 collaboration

Zhi Wang 1 collaboration

Tim Esbenshade 1 collaboration

Bryan McKibben 1 collaboration

Stephan Riedmaier 1 collaboration

Martin D Brand 1 collaboration

Charles A Schurman 1 collaboration

Serra Kaya 1 collaboration

Neha Dole 1 collaboration

Nadja M Maldonado Luna 1 collaboration

Natalia Castillo 1 collaboration

Ryan Potter 1 collaboration

Christina D King 1 collaboration

Jordan B Burton 1 collaboration

Simon Tang 1 collaboration

Eric Schaible 1 collaboration

Tamara Alliston 1 collaboration

Fei Wu 1 collaboration

Huixun Du 1 collaboration

Eliah Overbey 1 collaboration

JangKeun Kim 1 collaboration

Priya Makhijani 1 collaboration

Chad A Lerner 1 collaboration

Khiem Nguyen 1 collaboration

Jordan Baechle 1 collaboration

Taylor R Valentino 1 collaboration

Matias Fuentealba 1 collaboration

Juliet M Bartleson 1 collaboration

Heather Halaweh 1 collaboration

Shawn Winer 1 collaboration

Cem Meydan 1 collaboration

Francine Garrett-Bakelman 1 collaboration

Nazish Sayed 1 collaboration

Masafumi Muratani 1 collaboration

Herbert G Kasler 1 collaboration

Afshin Beheshti 1 collaboration

Christopher E Mason 1 collaboration

Lauren A Wimer 1 collaboration

Asia Davis-Castillo 1 collaboration

Nicholas Schaum 1 collaboration

Alyssa N Cavalier 1 collaboration

Devin Wahl 1 collaboration

Daniel S Lark 1 collaboration

Julie A Reisz 1 collaboration

Radha Daya 1 collaboration

Stefanie Deinhardt-Emmer 1 collaboration

Sharvari Deshpande 1 collaboration

Koji Kitazawa 1 collaboration

Allison B Herman 1 collaboration

Prasanna Ashok Kumar 1 collaboration

Carlos Anerillas 1 collaboration

Francesco Neri 1 collaboration

Nilay Köse-Vogel 1 collaboration

Antje Häder 1 collaboration

Kotb Abdelmohsen 1 collaboration

Bettina Löffler 1 collaboration

Myriam Gorospe 1 collaboration

Jackson Harrison 1 collaboration

Adrienne C Kirby 1 collaboration

Neil Athayde 1 collaboration

Araz Boghossian 1 collaboration

Wah Cheung 1 collaboration

Emma Inglis 1 collaboration

Kavita Maravar 1 collaboration

Melissa Luig 1 collaboration

Monica Hook 1 collaboration

Chisaka Kuehnemann 1 collaboration

Jun-Wei B Hughes 1 collaboration

Christopher D Wiley 1 collaboration

Grace S Maurer 1 collaboration

Amanda N Mercer 1 collaboration

Ellen M Quardokus 1 collaboration

Diane C Saunders 1 collaboration

Elizabeth McDonough 1 collaboration

John W Hickey 1 collaboration

Christopher Werlein 1 collaboration

Christine Surrette 1 collaboration

Presha Rajbhandari 1 collaboration

Anna Martinez Casals 1 collaboration

Hua Tian 1 collaboration

Lisa Lowery 1 collaboration

Elizabeth K Neumann 1 collaboration

Frida Björklund 1 collaboration

Taruna V Neelakantan 1 collaboration

Josh Croteau 1 collaboration

Anne E Wiblin 1 collaboration

Jeremy Fisher 1 collaboration

April J Livengood 1 collaboration

Karen G Dowell 1 collaboration

Jonathan C Silverstein 1 collaboration

Jeffrey M Spraggins 1 collaboration

Gloria S Pryhuber 1 collaboration

Gail Deutsch 1 collaboration

Fiona Ginty 1 collaboration

Garry P Nolan 1 collaboration

Danny Jonigk 1 collaboration

Michael A Caldwell 1 collaboration

Ioannis S Vlachos 1 collaboration

Werner Muller 1 collaboration

Nils Gehlenborg 1 collaboration

Brent R Stockwell 1 collaboration

Emma Lundberg 1 collaboration

Michael P Snyder 1 collaboration

Ronald N Germain 1 collaboration

Jeannie M Camarillo 1 collaboration

Neil L Kelleher 1 collaboration

Katy Börner 1 collaboration

Andrea J Radtke 1 collaboration

Mary A Darrah 1 collaboration

John C Newman 1 collaboration

Eric Verdin 1 collaboration

Simone Marschner 1 collaboration

Clara Chow 1 collaboration

Aravinda Thiagalingam 1 collaboration

David Simmons 1 collaboration

Mark McClean 1 collaboration

Ben J Smith 1 collaboration

Victoria Flood 1 collaboration

Cellina Ching 1 collaboration

N Wah Cheung 1 collaboration

Chase M Carver 1 collaboration

Paul T Gomez 1 collaboration

Sonia L Rodriguez 1 collaboration

Jennifer M Kachergus 1 collaboration

Yi Liu 1 collaboration

Ji Shi 1 collaboration

Tommy Tran 1 collaboration

Liguo Wang 1 collaboration

E Aubrey Thompson 1 collaboration

Marissa J Schafer 1 collaboration

Joshua P Nederveen 1 collaboration

Mats I Nilsson 1 collaboration

Mark Tarnopolsky 1 collaboration

Daniel S Evans 1 collaboration

Monique N O'Leary 1 collaboration

Ryan Murphy 1 collaboration

Minna Schmidt 1 collaboration

Kristin Koenig 1 collaboration

Michael Presley 1 collaboration

Brittany Garrett 1 collaboration

Ha-Neui Kim 1 collaboration

Li Han 1 collaboration

Emmeline C Academia 1 collaboration

Matt J Laye 1 collaboration

Daniel Edgar 1 collaboration

Christopher A Zambataro 1 collaboration

Tracey Barhydt 1 collaboration

Colleen M Dewey 1 collaboration

Jarrott Mayfield 1 collaboration

Joy Wilson 1 collaboration

Silvestre Alavez 1 collaboration

Mark Lucanic 1 collaboration

Brian K Kennedy 1 collaboration

Maria Almeida 1 collaboration

Julie K Andersen 1 collaboration

Brian A Hodge 1 collaboration

Geoffrey T Meyerhof 1 collaboration

Subhash D Katewa 1 collaboration

Ting Lian 1 collaboration

Charles Lau 1 collaboration

Sudipta Bar 1 collaboration

Nicole Y Leung 1 collaboration

Menglin Li 1 collaboration

David Li-Kroeger 1 collaboration

Craig Montell 1 collaboration

Monica Rikard-Bell 1 collaboration

James Elhindi 1 collaboration

Justin Lam 1 collaboration

Sean Seeho 1 collaboration

Kirsten Black 1 collaboration

Greg Jenkins 1 collaboration

Justin McNab 1 collaboration

Kerrie Wiley 1 collaboration

Lauren Wimer 1 collaboration

Elena Goncharova 1 collaboration

Edna Nyangau 1 collaboration

Mahalakshmi Shankaran 1 collaboration

Asia Davis 1 collaboration

Nicholas Shaum 1 collaboration

Mark Hellerstein 1 collaboration