S J Matkovich

Affiliations

Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA.

Publications (15)

Multiomic approaches to delineate the pathogenesis of cardiac disease.

Current opinion in cardiology

Avec: Scot J Matkovich

Simple nutrients bypass the requirement for HLH-30 in coupling lysosomal nutrient sensing to survival.

PLoS biology

Avec: John T Murphy , Haiyan Liu , Xiucui Ma , Alex Shaver , Brian M Egan , Clara Oh , Alexander Boyko , Travis Mazer , Samuel Ang , Rohan Khopkar , Ali Javaheri , Sandeep Kumar , Xuntian Jiang , Daniel Ory , Kartik Mani , Scot J Matkovich , Kerry Kornfeld , Abhinav Diwan

Necrotic cardiac myocytes skew macrophage polarization towards a classically activated phenotype.

PloS one

Avec: Wenlong Jiang , Luigi Adamo , Kenji Lim , Scot J Matkovich , Sarah Evans , Cibele Rocha-Resende , Douglas L Mann

Development of a long-acting relaxin analogue, LY3540378, for treatment of chronic heart failure.

British journal of pharmacology

Avec: Petra Verdino , Stacey L Lee , Fariba N Cooper , Steven R Cottle , Patrick F Grealish , Charlie C Hu , Catalina M Meyer , Joanne Lin , Victoria Copeland , Gina Porter , Richard L Schroeder , Tyran D Thompson , Leah L Porras , Asim Dey , Hong Y Zhang , Emily C Beebe , Scot J Matkovich , Tamer Coskun , Aldona M Balciunas , Andrea Ferrante , Robert Siegel , Laurent Malherbe , Nicoletta Bivi , Chad D Paavola , Ryan J Hansen , Matthew M Abernathy , Sylvia O Nwosu , Molly C Carr , Josef G Heuer , Xiaojun Wang

Selective sweep for an enhancer involucrin allele identifies skin barrier adaptation out of Africa.

Nature communications

Avec: Mary Elizabeth Mathyer , Erin A Brettmann , Alina D Schmidt , Zane A Goodwin , Inez Y Oh , Ashley M Quiggle , Eric Tycksen , Natasha Ramakrishnan , Scot J Matkovich , Emma Guttman-Yassky , John R Edwards , Cristina de Guzman Strong

Characterization of a robust mouse model of heart failure with preserved ejection fraction.

American journal of physiology. Heart and circulatory physiology

Avec: Dzmitry Matsiukevich , Attila Kovacs , Tiandao Li , Kristen Kokkonen-Simon , Scot J Matkovich , Sunday S Oladipupo , David M Ornitz

BET bromodomain inhibition attenuates cardiac phenotype in myocyte-specific lamin A/C-deficient mice.

The Journal of clinical investigation

Avec: Gaelle Auguste , Leila Rouhi , Scot J Matkovich , Cristian Coarfa , Matthew J Robertson , Grazyna Czernuszewicz , Priyatansh Gurha , Ali J Marian

Identification of Genes and Pathways Regulated by Lamin A in Heart.

Journal of the American Heart Association

Avec: Jordi Coste Pradas , Gaelle Auguste , Scot J Matkovich , Raffaella Lombardi , Suet Nee Chen , Tyrone Garnett , Kyle Chamberlain , Jalish Mahmud Riyad , Thomas Weber , Sanjay K Singh , Matthew J Robertson , Cristian Coarfa , Ali J Marian , Priyatansh Gurha

Genomic Reorganization of Lamin-Associated Domains in Cardiac Myocytes Is Associated With Differential Gene Expression and DNA Methylation in Human Dilated Cardiomyopathy.

Circulation research

Avec: Sirisha M Cheedipudi , Scot J Matkovich , Cristian Coarfa , Xin Hu , Matthew J Robertson , Mary Sweet , Matthew Taylor , Luisa Mestroni , Joseph Cleveland , James T Willerson , Priyatansh Gurha , Ali J Marian

Transcriptomic and Functional Analyses of Mitochondrial Dysfunction in Pressure Overload-Induced Right Ventricular Failure.

Journal of the American Heart Association

Avec: HyunTae V Hwang , Nefthi Sandeep , Ramesh V Nair , Dong-Qing Hu , Mingming Zhao , Ingrid S Lan , Giovanni Fajardo , Scot J Matkovich , Daniel Bernstein , Sushma Reddy

Immunomodulatory role of non-neuronal cholinergic signaling in myocardial injury.

JCI insight

Avec: Cibele Rocha-Resende , Carla Weinheimer , Geetika Bajpai , Luigi Adamo , Scot J Matkovich , Joel Schilling , Philip M Barger , Kory J Lavine , Douglas L Mann

TFEB activation in macrophages attenuates postmyocardial infarction ventricular dysfunction independently of ATG5-mediated autophagy.

JCI insight

Avec: Ali Javaheri , Geetika Bajpai , Antonino Picataggi , Smrithi Mani , Layla Foroughi , Hosannah Evie , Attila Kovacs , Carla J Weinheimer , Krzystztof Hyrc , Qingli Xiao , Andrea Ballabio , Jin-Moo Lee , Scot J Matkovich , Babak Razani , Joel D Schilling , Kory J Lavine , Abhinav Diwan

Loss of lipin 1-mediated phosphatidic acid phosphohydrolase activity in muscle leads to skeletal myopathy in mice.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Avec: George G Schweitzer , Sara L Collier , Zhouji Chen , Kyle S McCommis , Sara K Pittman , Jun Yoshino , Scot J Matkovich , Fong-Fu Hsu , Roman Chrast , James M Eaton , Thurl E Harris , Conrad C Weihl , Brian N Finck

The Mechanism of High-Output Cardiac Hypertrophy Arising From Potassium Channel Gain-of-Function in Cantú Syndrome.

Function (Oxford, England)

Avec: Conor McClenaghan , Yan Huang , Scot J Matkovich , Attila Kovacs , Carla J Weinheimer , Ron Perez , Thomas J Broekelmann , Theresa M Harter , Jin-Moo Lee , Maria S Remedi , Colin G Nichols

Macrophage secretion of miR-106b-5p causes renin-dependent hypertension.

Nature communications

Avec: J Oh , A E Riek , S M Bindom , J S Shao , R D Head , R A Barve , M S Sands , G Carmeliet , P Osei-Owusu , R H Knutsen , H Zhang , K J Blumer , C G Nichols , R P Mecham , Á Baldán , B A Benitez , M L Sequeira-Lopez , R A Gomez , C Bernal-Mizrachi

Réseau de co-auteurs

Scot J Matkovich 14 collaborations

Attila Kovacs 3 collaborations

Cristian Coarfa 3 collaborations

Matthew J Robertson 3 collaborations

Priyatansh Gurha 3 collaborations

Ali J Marian 3 collaborations

Ali Javaheri 2 collaborations

Abhinav Diwan 2 collaborations

Luigi Adamo 2 collaborations

Cibele Rocha-Resende 2 collaborations

Douglas L Mann 2 collaborations

Gaelle Auguste 2 collaborations

Geetika Bajpai 2 collaborations

Kory J Lavine 2 collaborations

Carla J Weinheimer 2 collaborations

Jin-Moo Lee 2 collaborations

John T Murphy 1 collaboration

Haiyan Liu 1 collaboration

Xiucui Ma 1 collaboration

Alex Shaver 1 collaboration

Brian M Egan 1 collaboration

Clara Oh 1 collaboration

Alexander Boyko 1 collaboration

Travis Mazer 1 collaboration

Samuel Ang 1 collaboration

Rohan Khopkar 1 collaboration

Sandeep Kumar 1 collaboration

Xuntian Jiang 1 collaboration

Daniel Ory 1 collaboration

Kartik Mani 1 collaboration

Kerry Kornfeld 1 collaboration

Wenlong Jiang 1 collaboration

Kenji Lim 1 collaboration

Sarah Evans 1 collaboration

Petra Verdino 1 collaboration

Stacey L Lee 1 collaboration

Fariba N Cooper 1 collaboration

Steven R Cottle 1 collaboration

Patrick F Grealish 1 collaboration

Charlie C Hu 1 collaboration

Catalina M Meyer 1 collaboration

Joanne Lin 1 collaboration

Victoria Copeland 1 collaboration

Gina Porter 1 collaboration

Richard L Schroeder 1 collaboration

Tyran D Thompson 1 collaboration

Leah L Porras 1 collaboration

Asim Dey 1 collaboration

Hong Y Zhang 1 collaboration

Emily C Beebe 1 collaboration

Tamer Coskun 1 collaboration

Aldona M Balciunas 1 collaboration

Andrea Ferrante 1 collaboration

Robert Siegel 1 collaboration

Laurent Malherbe 1 collaboration

Nicoletta Bivi 1 collaboration

Chad D Paavola 1 collaboration

Ryan J Hansen 1 collaboration

Matthew M Abernathy 1 collaboration

Sylvia O Nwosu 1 collaboration

Molly C Carr 1 collaboration

Josef G Heuer 1 collaboration

Xiaojun Wang 1 collaboration

Mary Elizabeth Mathyer 1 collaboration

Erin A Brettmann 1 collaboration

Alina D Schmidt 1 collaboration

Zane A Goodwin 1 collaboration

Inez Y Oh 1 collaboration

Ashley M Quiggle 1 collaboration

Eric Tycksen 1 collaboration

Natasha Ramakrishnan 1 collaboration

Emma Guttman-Yassky 1 collaboration

John R Edwards 1 collaboration

Cristina de Guzman Strong 1 collaboration

Dzmitry Matsiukevich 1 collaboration

Tiandao Li 1 collaboration

Kristen Kokkonen-Simon 1 collaboration

Sunday S Oladipupo 1 collaboration

David M Ornitz 1 collaboration

Leila Rouhi 1 collaboration

Grazyna Czernuszewicz 1 collaboration

Jordi Coste Pradas 1 collaboration

Raffaella Lombardi 1 collaboration

Suet Nee Chen 1 collaboration

Tyrone Garnett 1 collaboration

Kyle Chamberlain 1 collaboration

Jalish Mahmud Riyad 1 collaboration

Thomas Weber 1 collaboration

Sanjay K Singh 1 collaboration

Sirisha M Cheedipudi 1 collaboration

Xin Hu 1 collaboration

Mary Sweet 1 collaboration

Matthew Taylor 1 collaboration

Luisa Mestroni 1 collaboration

Joseph Cleveland 1 collaboration

James T Willerson 1 collaboration

HyunTae V Hwang 1 collaboration

Nefthi Sandeep 1 collaboration

Ramesh V Nair 1 collaboration

Dong-Qing Hu 1 collaboration

Mingming Zhao 1 collaboration

Ingrid S Lan 1 collaboration

Giovanni Fajardo 1 collaboration

Daniel Bernstein 1 collaboration

Sushma Reddy 1 collaboration

Carla Weinheimer 1 collaboration

Joel Schilling 1 collaboration

Philip M Barger 1 collaboration

Antonino Picataggi 1 collaboration

Smrithi Mani 1 collaboration

Layla Foroughi 1 collaboration

Hosannah Evie 1 collaboration

Krzystztof Hyrc 1 collaboration

Qingli Xiao 1 collaboration

Andrea Ballabio 1 collaboration

Babak Razani 1 collaboration

Joel D Schilling 1 collaboration

George G Schweitzer 1 collaboration

Sara L Collier 1 collaboration

Zhouji Chen 1 collaboration

Kyle S McCommis 1 collaboration

Sara K Pittman 1 collaboration

Jun Yoshino 1 collaboration

Fong-Fu Hsu 1 collaboration

Roman Chrast 1 collaboration

James M Eaton 1 collaboration

Thurl E Harris 1 collaboration

Conrad C Weihl 1 collaboration

Brian N Finck 1 collaboration

Conor McClenaghan 1 collaboration

Yan Huang 1 collaboration

Ron Perez 1 collaboration

Thomas J Broekelmann 1 collaboration

Theresa M Harter 1 collaboration

Maria S Remedi 1 collaboration

Colin G Nichols 1 collaboration

J Oh 1 collaboration

A E Riek 1 collaboration

S M Bindom 1 collaboration

J S Shao 1 collaboration

R D Head 1 collaboration

R A Barve 1 collaboration

M S Sands 1 collaboration

G Carmeliet 1 collaboration

P Osei-Owusu 1 collaboration

R H Knutsen 1 collaboration

H Zhang 1 collaboration

K J Blumer 1 collaboration

C G Nichols 1 collaboration

R P Mecham 1 collaboration

Á Baldán 1 collaboration

B A Benitez 1 collaboration

M L Sequeira-Lopez 1 collaboration

R A Gomez 1 collaboration

C Bernal-Mizrachi 1 collaboration