Roberta Bordone

Affiliations

Oncology Institute of Southern Switzerland, Bellinzona, Switzerland.

Publications (12)

Translational control of polyamine metabolism by CNBP is required for

eLife

Avec: Sonia Coni , Federica A Falconio , Marta Marzullo , Marzia Munafò , Benedetta Zuliani , Federica Mosti , Alessandro Fatica , Zaira Ianniello , Rosa Bordone , Alberto Macone , Enzo Agostinelli , Alessia Perna , Tanja Matkovic , Stephan Sigrist , Gabriella Silvestri , Gianluca Canettieri , Laura Ciapponi

The novel CD19-targeting antibody-drug conjugate huB4-DGN462 shows improved anti-tumor activity compared to SAR3419 in CD19-positive lymphoma and leukemia models.

Haematologica

Avec: Stuart W Hicks , Chiara Tarantelli , Alan Wilhem , Eugenio Gaudio , Min Li , Alberto J Arribas , Filippo Spriano , Luciano Cascione , Katharine C Lai , Qifeng Qiu , Monica Taborelli , Davide Rossi , Georg Stussi , Emanuele Zucca , Anastasios Stathis , Callum M Sloss , Francesco Bertoni

MYC upstream region orchestrates resistance to PI3K inhibitors in cancer cells through FOXO3a-mediated autophagic adaptation.

Oncogene

Avec: Rosa Bordone , Devon Michael Ivy , Rodrigo D'Amico , Martina Barba , Miriam Gaggianesi , Fiorella Di Pastena , Bianca Cesaro , Francesca Bufalieri , Alessio Balzerano , Enrico De Smaele , Giuseppe Giannini , Lucia Di Marcotullio , Alessandro Fatica , Giorgio Stassi , Laura Di Magno , Sonia Coni , Gianluca Canettieri

Targeting CD205 with the antibody drug conjugate MEN1309/OBT076 is an active new therapeutic strategy in lymphoma models.

Haematologica

Avec: Eugenio Gaudio , Chiara Tarantelli , Filippo Spriano , Francesca Guidetti , Giulio Sartori , Alberto J Arribas , Luciano Cascione , Mario Bigioni , Giuseppe Merlino , Alessio Fiascarelli , Alessandro Bressan , Afua Adjeiwaa Mensah , Gaetanina Golino , Renzo Lucchini , Elena Bernasconi , Davide Rossi , Emanuele Zucca , Georg Stussi , Anastasios Stathis , Robert S Boyd , Rachel L Dusek , Arnima Bisht , Nickolas Attanasio , Christian Rohlff , Andrea Pellacani , Monica Binaschi , Francesco Bertoni

Induction of Ferroptosis in Glioblastoma and Ovarian Cancers by a New Pyrrole Tubulin Assembly Inhibitor.

Journal of medicinal chemistry

Avec: Michela Puxeddu , Jianchao Wu , Ruoli Bai , Michele D'Ambrosio , Marianna Nalli , Antonio Coluccia , Simone Manetto , Alessia Ciogli , Domiziana Masci , Andrea Urbani , Cinzia Fionda , Sonia Coni , Rosa Bordone , Gianluca Canettieri , Chiara Bigogno , Giulio Dondio , Ernest Hamel , Te Liu , Romano Silvestri , Giuseppe La Regina

Partial Truncation of the C-Terminal Domain of PTCH1 in Cancer Enhances Autophagy and Metabolic Adaptability.

Cancers

Avec: Begoña Caballero-Ruiz , Danai S Gkotsi , Hattie Ollerton , Cintli C Morales-Alcala , Rosa Bordone , Georgia M L Jenkins , Laura Di Magno , Gianluca Canettieri , Natalia A Riobo-Del Galdo

Mitogen-activated kinase kinase kinase 1 inhibits hedgehog signaling and medulloblastoma growth through GLI1 phosphorylation.

International journal of oncology

Avec: Laura Antonucci , Laura Di Magno , Davide D'Amico , Simona Manni , Silvia Maria Serrao , Fiorella Di Pastena , Rosa Bordone , Zuleyha Nihan Yurtsever , Miriam Caimano , Marialaura Petroni , Alessandra Giorgi , Maria Eugenia Schininà , John R Yates Iii , Lucia Di Marcotullio , Enrico De Smaele , Saula Checquolo , Carlo Capalbo , Enzo Agostinelli , Marella Maroder , Sonia Coni , Gianluca Canettieri

Blockade of EIF5A hypusination limits colorectal cancer growth by inhibiting MYC elongation.

Cell death & disease

Avec: Sonia Coni , Silvia Maria Serrao , Zuleyha Nihan Yurtsever , Laura Di Magno , Rosa Bordone , Camilla Bertani , Valerio Licursi , Zaira Ianniello , Paola Infante , Marta Moretti , Marialaura Petroni , Francesca Guerrieri , Alessandro Fatica , Alberto Macone , Enrico De Smaele , Lucia Di Marcotullio , Giuseppe Giannini , Marella Maroder , Enzo Agostinelli , Gianluca Canettieri

4-(3-Phenyl-4-(3,4,5-trimethoxybenzoyl)-1

Journal of medicinal chemistry

Avec: Domiziana Masci , Michela Puxeddu , Laura Di Magno , Michele D'Ambrosio , Anastasia Parisi , Marianna Nalli , Ruoli Bai , Antonio Coluccia , Pietro Sciò , Viviana Orlando , Sara D'Angelo , Stefano Biagioni , Andrea Urbani , Ernest Hamel , Alessio Nocentini , Serena Filiberti , Marta Turati , Roberto Ronca , Joanna Kopecka , Chiara Riganti , Cinzia Fionda , Rosa Bordone , Giorgia Della Rocca , Gianluca Canettieri , Claudiu T Supuran , Romano Silvestri , Giuseppe La Regina

The Mechanism of Action of Biguanides: New Answers to a Complex Question.

Cancers

Avec: Laura Di Magno , Fiorella Di Pastena , Rosa Bordone , Sonia Coni , Gianluca Canettieri

Prophylaxis and hemophilia care in LATAM: Baring it all-Highlights from the CLAHT 2021 symposium.

EJHaem

Avec: Giovanni G DiMinno , Lida Milena Araujo Cabrera , Nancy Loayza Urcia , Raul Bordone , Carlos Martinez Murillo , Juan Carlos Beltran , Prasad Mathew

Combined inhibition of polyamine metabolism and eIF5A hypusination suppresses colorectal cancer growth through a converging effect on MYC translation.

Cancer letters

Avec: Sonia Coni , Rosa Bordone , Devon Michael Ivy , Zuleyha Nihan Yurtsever , Laura Di Magno , Rodrigo D'Amico , Bianca Cesaro , Alessandro Fatica , Francesca Belardinilli , Francesca Bufalieri , Marella Maroder , Enrico De Smaele , Lucia Di Marcotullio , Giuseppe Giannini , Enzo Agostinelli , Gianluca Canettieri

Réseau de co-auteurs

Rosa Bordone 9 collaborations

Gianluca Canettieri 9 collaborations

Sonia Coni 7 collaborations

Laura Di Magno 7 collaborations

Alessandro Fatica 4 collaborations

Enzo Agostinelli 4 collaborations

Enrico De Smaele 4 collaborations

Lucia Di Marcotullio 4 collaborations

Fiorella Di Pastena 3 collaborations

Giuseppe Giannini 3 collaborations

Zuleyha Nihan Yurtsever 3 collaborations

Marella Maroder 3 collaborations

Zaira Ianniello 2 collaborations

Alberto Macone 2 collaborations

Chiara Tarantelli 2 collaborations

Eugenio Gaudio 2 collaborations

Alberto J Arribas 2 collaborations

Filippo Spriano 2 collaborations

Luciano Cascione 2 collaborations

Davide Rossi 2 collaborations

Georg Stussi 2 collaborations

Emanuele Zucca 2 collaborations

Anastasios Stathis 2 collaborations

Francesco Bertoni 2 collaborations

Devon Michael Ivy 2 collaborations

Rodrigo D'Amico 2 collaborations

Bianca Cesaro 2 collaborations

Francesca Bufalieri 2 collaborations

Michela Puxeddu 2 collaborations

Ruoli Bai 2 collaborations

Michele D'Ambrosio 2 collaborations

Marianna Nalli 2 collaborations

Antonio Coluccia 2 collaborations

Domiziana Masci 2 collaborations

Andrea Urbani 2 collaborations

Cinzia Fionda 2 collaborations

Ernest Hamel 2 collaborations

Romano Silvestri 2 collaborations

Giuseppe La Regina 2 collaborations

Silvia Maria Serrao 2 collaborations

Marialaura Petroni 2 collaborations

Federica A Falconio 1 collaboration

Marta Marzullo 1 collaboration

Marzia Munafò 1 collaboration

Benedetta Zuliani 1 collaboration

Federica Mosti 1 collaboration

Alessia Perna 1 collaboration

Tanja Matkovic 1 collaboration

Stephan Sigrist 1 collaboration

Gabriella Silvestri 1 collaboration

Laura Ciapponi 1 collaboration

Stuart W Hicks 1 collaboration

Alan Wilhem 1 collaboration

Min Li 1 collaboration

Katharine C Lai 1 collaboration

Qifeng Qiu 1 collaboration

Monica Taborelli 1 collaboration

Callum M Sloss 1 collaboration

Martina Barba 1 collaboration

Miriam Gaggianesi 1 collaboration

Alessio Balzerano 1 collaboration

Giorgio Stassi 1 collaboration

Francesca Guidetti 1 collaboration

Giulio Sartori 1 collaboration

Mario Bigioni 1 collaboration

Giuseppe Merlino 1 collaboration

Alessio Fiascarelli 1 collaboration

Alessandro Bressan 1 collaboration

Afua Adjeiwaa Mensah 1 collaboration

Gaetanina Golino 1 collaboration

Renzo Lucchini 1 collaboration

Elena Bernasconi 1 collaboration

Robert S Boyd 1 collaboration

Rachel L Dusek 1 collaboration

Arnima Bisht 1 collaboration

Nickolas Attanasio 1 collaboration

Christian Rohlff 1 collaboration

Andrea Pellacani 1 collaboration

Monica Binaschi 1 collaboration

Jianchao Wu 1 collaboration

Simone Manetto 1 collaboration

Alessia Ciogli 1 collaboration

Chiara Bigogno 1 collaboration

Giulio Dondio 1 collaboration

Te Liu 1 collaboration

Begoña Caballero-Ruiz 1 collaboration

Danai S Gkotsi 1 collaboration

Hattie Ollerton 1 collaboration

Cintli C Morales-Alcala 1 collaboration

Georgia M L Jenkins 1 collaboration

Natalia A Riobo-Del Galdo 1 collaboration

Laura Antonucci 1 collaboration

Davide D'Amico 1 collaboration

Simona Manni 1 collaboration

Miriam Caimano 1 collaboration

Alessandra Giorgi 1 collaboration

Maria Eugenia Schininà 1 collaboration

John R Yates Iii 1 collaboration

Saula Checquolo 1 collaboration

Carlo Capalbo 1 collaboration

Camilla Bertani 1 collaboration

Valerio Licursi 1 collaboration

Paola Infante 1 collaboration

Marta Moretti 1 collaboration

Francesca Guerrieri 1 collaboration

Anastasia Parisi 1 collaboration

Pietro Sciò 1 collaboration

Viviana Orlando 1 collaboration

Sara D'Angelo 1 collaboration

Stefano Biagioni 1 collaboration

Alessio Nocentini 1 collaboration

Serena Filiberti 1 collaboration

Marta Turati 1 collaboration

Roberto Ronca 1 collaboration

Joanna Kopecka 1 collaboration

Chiara Riganti 1 collaboration

Giorgia Della Rocca 1 collaboration

Claudiu T Supuran 1 collaboration

Giovanni G DiMinno 1 collaboration

Lida Milena Araujo Cabrera 1 collaboration

Nancy Loayza Urcia 1 collaboration

Raul Bordone 1 collaboration

Carlos Martinez Murillo 1 collaboration

Juan Carlos Beltran 1 collaboration

Prasad Mathew 1 collaboration

Francesca Belardinilli 1 collaboration