Randall S MacGill

Affiliations

PATH Center for Vaccine Innovation and Access, Washington DC, USA.

ORCID: http://orcid.org/0000-0002-4566-1481

Publications (15)

A candidate antibody drug for prevention of malaria.

Nature medicine

Avec: Katherine L Williams , Steve Guerrero , Yevel Flores-Garcia , Dongkyoon Kim , Kevin S Williamson , Christine Siska , Pauline Smidt , Sofia Z Jepson , Kan Li , S Moses Dennison , Shamika Mathis-Torres , Xiaomu Chen , Ulrike Wille-Reece , Michael Walker , Erik Jongert , C Richter King , Christian Ockenhouse , Jacob Glanville , James E Moon , Jason A Regules , Yann Chong Tan , Guy Cavet , Shaun M Lippow , William H Robinson , Sheetij Dutta , Georgia D Tomaras , Fidel Zavala , Randal R Ketchem , Daniel E Emerling

Vaccination with synthetic long peptide formulated with CpG in an oil-in-water emulsion induces robust E7-specific CD8 T cell responses and TC-1 tumor eradication.

BMC cancer

Avec: Sean K Maynard , Jason D Marshall , Li Yu , Jennifer A Cann , Lily I Cheng , Michael P McCarthy , Corinne Cayatte , Scott H Robbins

Multiplex serological assay for establishing serological profiles of polymorphic, closely related peptide antigens.

MethodsX

Avec: Jessica Bolton , Sidhartha Chaudhury , Angela M Early , C Richter King , Emily Locke , Daniel E Neafsey , Elke S Bergmann-Leitner

Establishing RTS,S/AS01 as a benchmark for comparison to next-generation malaria vaccines in a mouse model.

NPJ vaccines

Avec: Emily Locke , Yevel Flores-Garcia , Bryan T Mayer , Bhavesh Borate , Berenice Salgado-Jimenez , Monica W Gerber , Shamika Mathis-Torres , Sarah Shapiro , C Richter King , Fidel Zavala

Analysis of the diverse antigenic landscape of the malaria protein RH5 identifies a potent vaccine-induced human public antibody clonotype.

Cell

Avec: Jordan R Barrett , Dimitra Pipini , Nathan D Wright , Andrew J R Cooper , Giacomo Gorini , Doris Quinkert , Amelia M Lias , Hannah Davies , Cassandra A Rigby , Maya Aleshnick , Barnabas G Williams , William J Bradshaw , Neil G Paterson , Thomas Martinson , Payton Kirtley , Luc Picard , Christine D Wiggins , Francesca R Donnellan , Lloyd D W King , Lawrence T Wang , Jonathan F Popplewell , Sarah E Silk , Jed de Ruiter Swain , Katherine Skinner , Vinayaka Kotraiah , Amy R Noe , C Richter King , Ashley J Birkett , Lorraine A Soisson , Angela M Minassian , Douglas A Lauffenburger , Kazutoyo Miura , Carole A Long , Brandon K Wilder , Lizbé Koekemoer , Joshua Tan , Carolyn M Nielsen , Kirsty McHugh , Simon J Draper

Breadth of humoral immune responses to the C-terminus of the circumsporozoite protein is associated with protective efficacy induced by the RTS,S malaria vaccine.

Vaccine

Avec: Sidhartha Chaudhury , Angela M Early , Jessica S Bolton , C Richter King , Emily Locke , Tony Pierson , Dyann F Wirth , Daniel E Neafsey , Elke S Bergmann-Leitner

A novel CSP C-terminal epitope targeted by an antibody with protective activity against Plasmodium falciparum.

PLoS pathogens

Avec: Nathan Beutler , Tossapol Pholcharee , David Oyen , Yevel Flores-Garcia , Elijah Garcia , Jaeson Calla , Mara Parren , Linlin Yang , Wayne Volkmuth , Emily Locke , Jason A Regules , Sheetij Dutta , Daniel Emerling , Angela M Early , Daniel E Neafsey , Elizabeth A Winzeler , C Richter King , Fidel Zavala , Dennis R Burton , Ian A Wilson , Thomas F Rogers

Affinity-matured homotypic interactions induce spectrum of PfCSP structures that influence protection from malaria infection.

Nature communications

Avec: Gregory M Martin , Jonathan L Torres , Tossapol Pholcharee , David Oyen , Yevel Flores-Garcia , Grace Gibson , Re'em Moskovitz , Nathan Beutler , Diana D Jung , Jeffrey Copps , Wen-Hsin Lee , Gonzalo Gonzalez-Paez , Daniel Emerling , Emily Locke , C Richter King , Fidel Zavala , Ian A Wilson , Andrew B Ward

Novel antibody competition binding assay identifies distinct serological profiles associated with protection.

Frontiers in immunology

Avec: Jessica S Bolton , Emily Locke , Jason A Regules , Elke S Bergmann-Leitner

Vaccination with a structure-based stabilized version of malarial antigen Pfs48/45 elicits ultra-potent transmission-blocking antibody responses.

Immunity

Avec: Brandon McLeod , Moustafa T Mabrouk , Kazutoyo Miura , Rashmi Ravichandran , Sally Kephart , Sophia Hailemariam , Thao P Pham , Anthony Semesi , Iga Kucharska , Prasun Kundu , Wei-Chiao Huang , Max Johnson , Alyssa Blackstone , Deleah Pettie , Michael Murphy , John C Kraft , Elizabeth M Leaf , Yang Jiao , Marga van de Vegte-Bolmer , Geert-Jan van Gemert , Jordache Ramjith , C Richter King , Yimin Wu , Kelly K Lee , Matthijs M Jore , Neil P King , Jonathan F Lovell , Jean-Philippe Julien

Highly potent, naturally acquired human monoclonal antibodies against Pfs48/45 block Plasmodium falciparum transmission to mosquitoes.

Immunity

Avec: Amanda Fabra-García , Sophia Hailemariam , Roos M de Jong , Kirsten Janssen , Karina Teelen , Marga van de Vegte-Bolmer , Geert-Jan van Gemert , Danton Ivanochko , Anthony Semesi , Brandon McLeod , Martijn W Vos , Marloes H C de Bruijni , Judith M Bolscher , Marta Szabat , Stefanie Vogt , Lucas Kraft , Sherie Duncan , Moses R Kamya , Margaret E Feeney , Prasanna Jagannathan , Bryan Greenhouse , Koen J Dechering , Robert W Sauerwein , C Richter King , Teun Bousema , Jean-Philippe Julien , Matthijs M Jore

Target-agnostic identification of human antibodies to

bioRxiv : the preprint server for biology

Avec: Axelle Amen , Randy Yoo , Amanda Fabra-García , Judith Bolscher , William J R Stone , Isabelle Bally , Sebastián Dergan-Dylon , Iga Kucharska , Roos M de Jong , Marloes de Bruijni , Teun Bousema , C Richter King , Robert W Sauerwein , Jean-Philippe Julien , Pascal Poignard , Matthijs M Jore

Potent transmission-blocking monoclonal antibodies from naturally exposed individuals target a conserved epitope on Plasmodium falciparum Pfs230.

Immunity

Avec: Danton Ivanochko , Amanda Fabra-García , Karina Teelen , Marga van de Vegte-Bolmer , Geert-Jan van Gemert , Jocelyn Newton , Anthony Semesi , Marloes de Bruijni , Judith Bolscher , Jordache Ramjith , Marta Szabat , Stefanie Vogt , Lucas Kraft , Sherie Duncan , Shwu-Maan Lee , Moses R Kamya , Margaret E Feeney , Prasanna Jagannathan , Bryan Greenhouse , Robert W Sauerwein , C Richter King , Teun Bousema , Matthijs M Jore , Jean-Philippe Julien

Development of an improved blood-stage malaria vaccine targeting the essential RH5-CyRPA-RIPR invasion complex.

Nature communications

Avec: Barnabas G Williams , Lloyd D W King , David Pulido , Doris Quinkert , Amelia M Lias , Sarah E Silk , Robert J Ragotte , Hannah Davies , Jordan R Barrett , Kirsty McHugh , Cassandra A Rigby , Daniel G W Alanine , Lea Barfod , Michael W Shea , Li An Cowley , Rebecca A Dabbs , David J Pattinson , Alexander D Douglas , Oliver R Lyth , Joseph J Illingworth , Jing Jin , Cecilia Carnrot , Vinayaka Kotraiah , Jayne M Christen , Amy R Noe , C Richter King , Ashley J Birkett , Lorraine A Soisson , Katherine Skinner , Kazutoyo Miura , Carole A Long , Matthew K Higgins , Simon J Draper

Preclinical development of a stabilized RH5 virus-like particle vaccine that induces improved antimalarial antibodies.

Cell reports. Medicine

Avec: Lloyd D W King , David Pulido , Jordan R Barrett , Hannah Davies , Doris Quinkert , Amelia M Lias , Sarah E Silk , David J Pattinson , Ababacar Diouf , Barnabas G Williams , Kirsty McHugh , Ana Rodrigues , Cassandra A Rigby , Veronica Strazza , Jonathan Suurbaar , Chloe Rees-Spear , Rebecca A Dabbs , Andrew S Ishizuka , Yu Zhou , Gaurav Gupta , Jing Jin , Yuanyuan Li , Cecilia Carnrot , Angela M Minassian , Ivan Campeotto , Sarel J Fleishman , Amy R Noe , C Richter King , Ashley J Birkett , Lorraine A Soisson , Carole A Long , Kazutoyo Miura , Rebecca Ashfield , Katherine Skinner , Mark R Howarth , Sumi Biswas , Simon J Draper

Réseau de co-auteurs

C Richter King 13 collaborations

Emily Locke 6 collaborations

Yevel Flores-Garcia 4 collaborations

Fidel Zavala 4 collaborations

Kazutoyo Miura 4 collaborations

Matthijs M Jore 4 collaborations

Jean-Philippe Julien 4 collaborations

Jason A Regules 3 collaborations

Angela M Early 3 collaborations

Daniel E Neafsey 3 collaborations

Elke S Bergmann-Leitner 3 collaborations

Jordan R Barrett 3 collaborations

Doris Quinkert 3 collaborations

Amelia M Lias 3 collaborations

Hannah Davies 3 collaborations

Cassandra A Rigby 3 collaborations

Barnabas G Williams 3 collaborations

Lloyd D W King 3 collaborations

Sarah E Silk 3 collaborations

Katherine Skinner 3 collaborations

Amy R Noe 3 collaborations

Ashley J Birkett 3 collaborations

Lorraine A Soisson 3 collaborations

Carole A Long 3 collaborations

Kirsty McHugh 3 collaborations

Simon J Draper 3 collaborations

Anthony Semesi 3 collaborations

Marga van de Vegte-Bolmer 3 collaborations

Geert-Jan van Gemert 3 collaborations

Amanda Fabra-García 3 collaborations

Robert W Sauerwein 3 collaborations

Teun Bousema 3 collaborations

Shamika Mathis-Torres 2 collaborations

Sheetij Dutta 2 collaborations

Sidhartha Chaudhury 2 collaborations

Vinayaka Kotraiah 2 collaborations

Angela M Minassian 2 collaborations

Jessica S Bolton 2 collaborations

Nathan Beutler 2 collaborations

Tossapol Pholcharee 2 collaborations

David Oyen 2 collaborations

Daniel Emerling 2 collaborations

Ian A Wilson 2 collaborations

Brandon McLeod 2 collaborations

Sophia Hailemariam 2 collaborations

Iga Kucharska 2 collaborations

Jordache Ramjith 2 collaborations

Roos M de Jong 2 collaborations

Karina Teelen 2 collaborations

Danton Ivanochko 2 collaborations

Marta Szabat 2 collaborations

Stefanie Vogt 2 collaborations

Lucas Kraft 2 collaborations

Sherie Duncan 2 collaborations

Moses R Kamya 2 collaborations

Margaret E Feeney 2 collaborations

Prasanna Jagannathan 2 collaborations

Bryan Greenhouse 2 collaborations

Judith Bolscher 2 collaborations

Marloes de Bruijni 2 collaborations

David Pulido 2 collaborations

Rebecca A Dabbs 2 collaborations

David J Pattinson 2 collaborations

Jing Jin 2 collaborations

Cecilia Carnrot 2 collaborations

Katherine L Williams 1 collaboration

Steve Guerrero 1 collaboration

Dongkyoon Kim 1 collaboration

Kevin S Williamson 1 collaboration

Christine Siska 1 collaboration

Pauline Smidt 1 collaboration

Sofia Z Jepson 1 collaboration

Kan Li 1 collaboration

S Moses Dennison 1 collaboration

Xiaomu Chen 1 collaboration

Ulrike Wille-Reece 1 collaboration

Michael Walker 1 collaboration

Erik Jongert 1 collaboration

Christian Ockenhouse 1 collaboration

Jacob Glanville 1 collaboration

James E Moon 1 collaboration

Yann Chong Tan 1 collaboration

Guy Cavet 1 collaboration

Shaun M Lippow 1 collaboration

William H Robinson 1 collaboration

Georgia D Tomaras 1 collaboration

Randal R Ketchem 1 collaboration

Daniel E Emerling 1 collaboration

Sean K Maynard 1 collaboration

Jason D Marshall 1 collaboration

Li Yu 1 collaboration

Jennifer A Cann 1 collaboration

Lily I Cheng 1 collaboration

Michael P McCarthy 1 collaboration

Corinne Cayatte 1 collaboration

Scott H Robbins 1 collaboration

Jessica Bolton 1 collaboration

Bryan T Mayer 1 collaboration

Bhavesh Borate 1 collaboration

Berenice Salgado-Jimenez 1 collaboration

Monica W Gerber 1 collaboration

Sarah Shapiro 1 collaboration

Dimitra Pipini 1 collaboration

Nathan D Wright 1 collaboration

Andrew J R Cooper 1 collaboration

Giacomo Gorini 1 collaboration

Maya Aleshnick 1 collaboration

William J Bradshaw 1 collaboration

Neil G Paterson 1 collaboration

Thomas Martinson 1 collaboration

Payton Kirtley 1 collaboration

Luc Picard 1 collaboration

Christine D Wiggins 1 collaboration

Francesca R Donnellan 1 collaboration

Lawrence T Wang 1 collaboration

Jonathan F Popplewell 1 collaboration

Jed de Ruiter Swain 1 collaboration

Douglas A Lauffenburger 1 collaboration

Brandon K Wilder 1 collaboration

Lizbé Koekemoer 1 collaboration

Joshua Tan 1 collaboration

Carolyn M Nielsen 1 collaboration

Tony Pierson 1 collaboration

Dyann F Wirth 1 collaboration

Elijah Garcia 1 collaboration

Jaeson Calla 1 collaboration

Mara Parren 1 collaboration

Linlin Yang 1 collaboration

Wayne Volkmuth 1 collaboration

Elizabeth A Winzeler 1 collaboration

Dennis R Burton 1 collaboration

Thomas F Rogers 1 collaboration

Gregory M Martin 1 collaboration

Jonathan L Torres 1 collaboration

Grace Gibson 1 collaboration

Re'em Moskovitz 1 collaboration

Diana D Jung 1 collaboration

Jeffrey Copps 1 collaboration

Wen-Hsin Lee 1 collaboration

Gonzalo Gonzalez-Paez 1 collaboration

Andrew B Ward 1 collaboration

Moustafa T Mabrouk 1 collaboration

Rashmi Ravichandran 1 collaboration

Sally Kephart 1 collaboration

Thao P Pham 1 collaboration

Prasun Kundu 1 collaboration

Wei-Chiao Huang 1 collaboration

Max Johnson 1 collaboration

Alyssa Blackstone 1 collaboration

Deleah Pettie 1 collaboration

Michael Murphy 1 collaboration

John C Kraft 1 collaboration

Elizabeth M Leaf 1 collaboration

Yang Jiao 1 collaboration

Yimin Wu 1 collaboration

Kelly K Lee 1 collaboration

Neil P King 1 collaboration

Jonathan F Lovell 1 collaboration

Kirsten Janssen 1 collaboration

Martijn W Vos 1 collaboration

Marloes H C de Bruijni 1 collaboration

Judith M Bolscher 1 collaboration

Koen J Dechering 1 collaboration

Axelle Amen 1 collaboration

Randy Yoo 1 collaboration

William J R Stone 1 collaboration

Isabelle Bally 1 collaboration

Sebastián Dergan-Dylon 1 collaboration

Pascal Poignard 1 collaboration

Jocelyn Newton 1 collaboration

Shwu-Maan Lee 1 collaboration

Robert J Ragotte 1 collaboration

Daniel G W Alanine 1 collaboration

Lea Barfod 1 collaboration

Michael W Shea 1 collaboration

Li An Cowley 1 collaboration

Alexander D Douglas 1 collaboration

Oliver R Lyth 1 collaboration

Joseph J Illingworth 1 collaboration

Jayne M Christen 1 collaboration

Matthew K Higgins 1 collaboration

Ababacar Diouf 1 collaboration

Ana Rodrigues 1 collaboration

Veronica Strazza 1 collaboration

Jonathan Suurbaar 1 collaboration

Chloe Rees-Spear 1 collaboration

Andrew S Ishizuka 1 collaboration

Yu Zhou 1 collaboration

Gaurav Gupta 1 collaboration

Yuanyuan Li 1 collaboration

Ivan Campeotto 1 collaboration

Sarel J Fleishman 1 collaboration

Rebecca Ashfield 1 collaboration

Mark R Howarth 1 collaboration

Sumi Biswas 1 collaboration