R Wireman

Affiliations

Department of Pediatrics and Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, IN, USA.

Publications (5)

Combined inhibition of Ref-1 and STAT3 leads to synergistic tumour inhibition in multiple cancers using 3D and in vivo tumour co-culture models.

Journal of cellular and molecular medicine

Avec: Rachel A Caston , Fenil Shah , Colton L Starcher , Randall Wireman , Olivia Babb , Michelle Grimard , Jack McGeown , Lee Armstrong , Yan Tong , Roberto Pili , Joseph Rupert , Teresa A Zimmers , Adily N Elmi , Karen E Pollok , Edward A Motea , Mark R Kelley , Melissa L Fishel

New Ref-1/APE1 targeted inhibitors demonstrating improved potency for clinical applications in multiple cancer types.

Pharmacological research

Avec: Silpa Gampala , Hye-Ran Moon , Randall Wireman , Jacqueline Peil , Sonia Kiran , Dana K Mitchell , Kylee Brewster , Henry Mang , Andi Masters , Christine Bach , Whitney Smith-Kinnamen , Emma H Doud , Ratan Rai , Amber L Mosley , Sara K Quinney , D Wade Clapp , Chafiq Hamdouchi , James Wikel , Chi Zhang , Bumsoo Han , Millie M Georgiadis , Mark R Kelley , Melissa L Fishel

RelA Is an Essential Target for Enhancing Cellular Responses to the DNA Repair/Ref-1 Redox Signaling Protein and Restoring Perturbated Cellular Redox Homeostasis in Mouse PDAC Cells.

Frontiers in oncology

Avec: Mahmut Mijit , Randall Wireman , Lee Armstrong , Silpa Gampala , Zonera Hassan , Christian Schneeweis , Guenter Schneider , Chi Zhang , Melissa L Fishel , Mark R Kelley

Discovery of Macrocyclic Inhibitors of Apurinic/Apyrimidinic Endonuclease 1.

Journal of medicinal chemistry

Avec: Richard Trilles , Dmitri Beglov , Qiujia Chen , Hongzhen He , Randall Wireman , April Reed , Spandan Chennamadhavuni , James S Panek , Lauren E Brown , Sandor Vajda , John A Porco , Mark R Kelley , Millie M Georgiadis

In vitro and In vivo evidence demonstrating chronic absence of Ref-1 Cysteine 65 impacts Ref-1 folding configuration, redox signaling, proliferation and metastasis in pancreatic cancer.

Redox biology

Avec: M Mijit , E Kpenu , N N Chowdhury , S Gampala , S Liu , O Babb , M M Georgiadis , J Wan , M L Fishel , M R Kelley

Réseau de co-auteurs

Randall Wireman 4 collaborations

Mark R Kelley 4 collaborations

Melissa L Fishel 3 collaborations

Lee Armstrong 2 collaborations

Silpa Gampala 2 collaborations

Chi Zhang 2 collaborations

Millie M Georgiadis 2 collaborations

Rachel A Caston 1 collaboration

Fenil Shah 1 collaboration

Colton L Starcher 1 collaboration

Olivia Babb 1 collaboration

Michelle Grimard 1 collaboration

Jack McGeown 1 collaboration

Yan Tong 1 collaboration

Roberto Pili 1 collaboration

Joseph Rupert 1 collaboration

Teresa A Zimmers 1 collaboration

Adily N Elmi 1 collaboration

Karen E Pollok 1 collaboration

Edward A Motea 1 collaboration

Hye-Ran Moon 1 collaboration

Jacqueline Peil 1 collaboration

Sonia Kiran 1 collaboration

Dana K Mitchell 1 collaboration

Kylee Brewster 1 collaboration

Henry Mang 1 collaboration

Andi Masters 1 collaboration

Christine Bach 1 collaboration

Whitney Smith-Kinnamen 1 collaboration

Emma H Doud 1 collaboration

Ratan Rai 1 collaboration

Amber L Mosley 1 collaboration

Sara K Quinney 1 collaboration

D Wade Clapp 1 collaboration

Chafiq Hamdouchi 1 collaboration

James Wikel 1 collaboration

Bumsoo Han 1 collaboration

Mahmut Mijit 1 collaboration

Zonera Hassan 1 collaboration

Christian Schneeweis 1 collaboration

Guenter Schneider 1 collaboration

Richard Trilles 1 collaboration

Dmitri Beglov 1 collaboration

Qiujia Chen 1 collaboration

Hongzhen He 1 collaboration

April Reed 1 collaboration

Spandan Chennamadhavuni 1 collaboration

James S Panek 1 collaboration

Lauren E Brown 1 collaboration

Sandor Vajda 1 collaboration

John A Porco 1 collaboration

M Mijit 1 collaboration

E Kpenu 1 collaboration

N N Chowdhury 1 collaboration

S Gampala 1 collaboration

S Liu 1 collaboration

O Babb 1 collaboration

M M Georgiadis 1 collaboration

J Wan 1 collaboration

M L Fishel 1 collaboration

M R Kelley 1 collaboration