Pierre-André Gilormini

Affiliations

Department of Chemistry and Simon Fraser University, Burnaby, British Columbia, Canada. dvocadlo@sfu.ca.

Publications (11)

Rational design of cell active C2-modified DGJ analogues for the inhibition of human α-galactosidase A (GALA).

Organic & biomolecular chemistry

Avec: Roger A Ashmus , Yang Wang , Manuel González-Cuesta , Dustin T King , Ben Tiet , José M García Fernández , Carmen Ortiz Mellet , Robert Britton , David J Vocadlo

Quantifying lysosomal glycosidase activity within cells using bis-acetal substrates.

Nature chemical biology

Avec: Samy Cecioni , Roger A Ashmus , Sha Zhu , Xi Chen , Xiaoyang Shan , Christina Gros , Matthew C Deen , Yang Wang , Robert Britton , David J Vocadlo

Strategies for quantifying the enzymatic activities of glycoside hydrolases within cells and in vivo.

Current opinion in chemical biology

Avec: Matthew C Deen , David J Vocadlo

Direct and indirect regulation of β-glucocerebrosidase by the transcription factors USF2 and ONECUT2.

NPJ Parkinson's disease

Avec: Kathi Ging , Lukas Frick , Johannes Schlachetzki , Andrea Armani , Yanping Zhu , Ashutosh Dhingra , Desirée Böck , Ana Marques , Matthew Deen , Xi Chen , Tetiana Serdiuk , Chiara Trevisan , Stefano Sellitto , Claudio Pisano , Christopher K Glass , Peter Heutink , Jiang-An Yin , David J Vocadlo , Adriano Aguzzi

Amino Acids Bearing Aromatic or Heteroaromatic Substituents as a New Class of Ligands for the Lysosomal Sialic Acid Transporter Sialin.

Journal of medicinal chemistry

Avec: Lilian Dubois , Nicolas Pietrancosta , Alexandre Cabaye , Isabelle Fanget , Cécile Debacker , Patrick M Dansette , Julien Dairou , Christophe Biot , Roseline Froissart , Anne Goupil-Lamy , Hugues-Olivier Bertrand , Francine C Acher , Isabelle McCort-Tranchepain , Bruno Gasnier , Christine Anne

A novel C-domain-dependent inhibition of the rainbow trout CMP-sialic acid synthetase activity by CMP-deaminoneuraminic acid.

Biochemical and biophysical research communications

Avec: Di Wu , Sakura Toda , Christophe Biot , Cédric Lion , Yann Guérardel , Chihiro Sato , Ken Kitajima

A versatile fluorescence-quenched substrate for quantitative measurement of glucocerebrosidase activity within live cells.

Proceedings of the National Academy of Sciences of the United States of America

Avec: Matthew C Deen , Yanping Zhu , Christina Gros , Na Na , David L Shen , Sandeep Bhosale , Nadia Anastasi , RuiQi Wang , Xiaoyang Shan , Eva Harde , Ravi Jagasia , Francis C Lynn , David J Vocadlo

Novel Zebrafish Mono-α2,8-sialyltransferase (ST8Sia VIII): An Evolutionary Perspective of α2,8-Sialylation.

International journal of molecular sciences

Avec: Lan-Yi Chang , Elin Teppa , Maxence Noel , Mathieu Decloquement , Cédric Lion , Christophe Biot , Anne-Marie Mir , Virginie Cogez , Philippe Delannoy , Kay Hooi Khoo , Daniel Petit , Yann Guérardel , Anne Harduin-Lepers

A Fixable Fluorescence-Quenched Substrate for Quantitation of Lysosomal Glucocerebrosidase Activity in Both Live and Fixed Cells.

Angewandte Chemie (International ed. in English)

Avec: Sha Zhu , Matthew C Deen , Yanping Zhu , Xi Chen , Oliver B Davis , Marcus Y Chin , Anastasia G Henry , David J Vocadlo

A metabolic inhibitor blocks cellular fucosylation and enables production of afucosylated antibodies.

Proceedings of the National Academy of Sciences of the United States of America

Avec: V Narasimharao Thota , Anthony Fers-Lidou , Roger A Ashmus , Matthew Nodwell , Jacob Brockerman , Chu-Wei Kuo , Yang Wang , Taylor E Gray , Nitin , Anthony W McDonagh , Shih-Yun Guu , Nursah Ertunc , Dominick Yeo , Wesley F Zandberg , Kay-Hooi Khoo , Robert Britton , David J Vocadlo

Development of Tunable Mechanism-Based Carbasugar Ligands that Stabilize Glycoside Hydrolases through the Formation of Transient Covalent Intermediates.

ACS catalysis

Avec: Sandeep Bhosale , Sachin Kandalkar , Oluwafemi Akintola , Rhianna Rowland , Pal John Pal Adabala , Dustin King , Matthew C Deen , Xi Chen , Gideon J Davies , David J Vocadlo , Andrew J Bennet

Réseau de co-auteurs

David J Vocadlo 8 collaborations

Matthew C Deen 5 collaborations

Xi Chen 4 collaborations

Roger A Ashmus 3 collaborations

Yang Wang 3 collaborations

Robert Britton 3 collaborations

Yanping Zhu 3 collaborations

Christophe Biot 3 collaborations

Sha Zhu 2 collaborations

Xiaoyang Shan 2 collaborations

Christina Gros 2 collaborations

Cédric Lion 2 collaborations

Yann Guérardel 2 collaborations

Sandeep Bhosale 2 collaborations

Manuel González-Cuesta 1 collaboration

Dustin T King 1 collaboration

Ben Tiet 1 collaboration

José M García Fernández 1 collaboration

Carmen Ortiz Mellet 1 collaboration

Samy Cecioni 1 collaboration

Kathi Ging 1 collaboration

Lukas Frick 1 collaboration

Johannes Schlachetzki 1 collaboration

Andrea Armani 1 collaboration

Ashutosh Dhingra 1 collaboration

Desirée Böck 1 collaboration

Ana Marques 1 collaboration

Matthew Deen 1 collaboration

Tetiana Serdiuk 1 collaboration

Chiara Trevisan 1 collaboration

Stefano Sellitto 1 collaboration

Claudio Pisano 1 collaboration

Christopher K Glass 1 collaboration

Peter Heutink 1 collaboration

Jiang-An Yin 1 collaboration

Adriano Aguzzi 1 collaboration

Lilian Dubois 1 collaboration

Nicolas Pietrancosta 1 collaboration

Alexandre Cabaye 1 collaboration

Isabelle Fanget 1 collaboration

Cécile Debacker 1 collaboration

Patrick M Dansette 1 collaboration

Julien Dairou 1 collaboration

Roseline Froissart 1 collaboration

Anne Goupil-Lamy 1 collaboration

Hugues-Olivier Bertrand 1 collaboration

Francine C Acher 1 collaboration

Isabelle McCort-Tranchepain 1 collaboration

Bruno Gasnier 1 collaboration

Christine Anne 1 collaboration

Di Wu 1 collaboration

Sakura Toda 1 collaboration

Chihiro Sato 1 collaboration

Ken Kitajima 1 collaboration

Na Na 1 collaboration

David L Shen 1 collaboration

Nadia Anastasi 1 collaboration

RuiQi Wang 1 collaboration

Eva Harde 1 collaboration

Ravi Jagasia 1 collaboration

Francis C Lynn 1 collaboration

Lan-Yi Chang 1 collaboration

Elin Teppa 1 collaboration

Maxence Noel 1 collaboration

Mathieu Decloquement 1 collaboration

Anne-Marie Mir 1 collaboration

Virginie Cogez 1 collaboration

Philippe Delannoy 1 collaboration

Kay Hooi Khoo 1 collaboration

Daniel Petit 1 collaboration

Anne Harduin-Lepers 1 collaboration

Oliver B Davis 1 collaboration

Marcus Y Chin 1 collaboration

Anastasia G Henry 1 collaboration

V Narasimharao Thota 1 collaboration

Anthony Fers-Lidou 1 collaboration

Matthew Nodwell 1 collaboration

Jacob Brockerman 1 collaboration

Chu-Wei Kuo 1 collaboration

Taylor E Gray 1 collaboration

None Nitin 1 collaboration

Anthony W McDonagh 1 collaboration

Shih-Yun Guu 1 collaboration

Nursah Ertunc 1 collaboration

Dominick Yeo 1 collaboration

Wesley F Zandberg 1 collaboration

Kay-Hooi Khoo 1 collaboration

Sachin Kandalkar 1 collaboration

Oluwafemi Akintola 1 collaboration

Rhianna Rowland 1 collaboration

Pal John Pal Adabala 1 collaboration

Dustin King 1 collaboration

Gideon J Davies 1 collaboration

Andrew J Bennet 1 collaboration