Oliver Politz

Affiliations

Bayer AG, Preclinical Research Oncology, Berlin, Germany.

ORCID: 0000-0002-0272-6249

Publications (11)

Preclinical Activity of PI3K Inhibitor Copanlisib in Gastrointestinal Stromal Tumor.

Molecular cancer therapeutics

Avec: Alfonso García-Valverde , Jordi Rosell , Garazi Serna , Claudia Valverde , Joan Carles , Paolo Nuciforo , Jonathan A Fletcher , Joaquín Arribas , César Serrano

Copanlisib synergizes with conventional and targeted agents including venetoclax in B- and T-cell lymphoma models.

Blood advances

Avec: Chiara Tarantelli , Martin Lange , Eugenio Gaudio , Luciano Cascione , Filippo Spriano , Ivo Kwee , Alberto J Arribas , Andrea Rinaldi , Thibaud Jourdan , Melanie Berthold , Andrea Sturz , Carolyn Sperl , Francesco Margheriti , Lorenzo Scalise , Giuseppe Gritti , Davide Rossi , Anastasios Stathis , Ningshu Liu , Emanuele Zucca , Francesco Bertoni

Sorafenib/MEK inhibitor combination inhibits tumor growth and the Wnt/β‑catenin pathway in xenograft models of hepatocellular carcinoma.

International journal of oncology

Avec: Hung Huynh , Richard Ong , Kah Yong Goh , Liek Yeow Lee , Florian Puehler , Arne Scholz , Dominik Mumberg , Karl Ziegelbauer

A Targeted Thorium-227 Conjugate Demonstrates Efficacy in Preclinical Models of Acquired Drug Resistance and Combination Potential with Chemotherapeutics and Antiangiogenic Therapies.

Molecular cancer therapeutics

Avec: Sabine Zitzmann-Kolbe , Alexander Kristian , Dieter Zopf , Claudia Kamfenkel , Christine Ellingsen , Jochen Hilbig , Mark U Juul , Jesper Fonslet , Carsten H Nielsen , Christoph A Schatz , Roger M Bjerke , Alan S Cuthbertson , Dominik Mumberg , Urs B Hagemann

The ATR inhibitor elimusertib exhibits anti-lymphoma activity and synergizes with the PI3K inhibitor copanlisib.

British journal of haematology

Avec: Giulio Sartori , Chiara Tarantelli , Filippo Spriano , Eugenio Gaudio , Luciano Cascione , Michele Mascia , Marilia Barreca , Alberto J Arribas , Luca Licenziato , Gaetanina Golino , Adele Ferragamo , Stefano Pileri , Giovanna Damia , Emanuele Zucca , Anastasios Stathis , Antje M Wengner , Francesco Bertoni

Rogaratinib: A potent and selective pan-FGFR inhibitor with broad antitumor activity in FGFR-overexpressing preclinical cancer models.

International journal of cancer

Avec: Sylvia Grünewald , Sebastian Bender , Mélanie Héroult , Klemens Lustig , Uwe Thuss , Christoph Kneip , Charlotte Kopitz , Dieter Zopf , Marie-Pierre Collin , Ulf Boemer , Stuart Ince , Peter Ellinghaus , Dominik Mumberg , Holger Hess-Stumpp , Karl Ziegelbauer

Combination of copanlisib with cetuximab improves tumor response in cetuximab-resistant patient-derived xenografts of head and neck cancer.

Oncotarget

Avec: Konrad Klinghammer , Theresa Eder , Raik Otto , Jan-Dirk Raguse , Andreas Albers , Andreas Kaufmann , Ingeborg Tinhofer , Jens Hoffmann , Ulrich Keller , Ulrich Keilholz

Pan-PI3K inhibition with copanlisib overcomes Treg- and M2-TAM-mediated immune suppression and promotes anti-tumor immune responses.

Clinical and experimental medicine

Avec: Simon Heller , Sarah Glaeske , Katja Gluske , Juliane Paul , Annika Böhme , Andreas Janzer , Helge Gottfried Roider , Anna Montebaur , Barbara Nicke , Ralf Lesche , Oliver von Ahsen , Ningshu Liu , Mátyás Gorjánácz

Evaluation of the PIK3 pathway in peripheral T-cell lymphoma and NK/T-cell lymphoma.

British journal of haematology

Avec: Dachuan Huang , Tammy Linlin Song , Maarja-Liisa Nairismägi , Yurike Laurensia , Wan-Lu Pang , Daryl Cheah Ming Zhe , Esther Kam Yin Wong , Giovani Giovani-Clarest Wijaya , Jing Tan , Sze Huey Tan , Jing-Quan Lim , Burton Kuan Hui Chia , Jason Yongsheng Chan , Tiffany Pooi Ling Tang , Nagavalli Somasundaram , Chee Leong Cheng , Ningshu Liu , Soon Thye Lim , Choon Kiat Ong

Addressing the Reciprocal Crosstalk between the AR and the PI3K/AKT/mTOR Signaling Pathways for Prostate Cancer Treatment.

International journal of molecular sciences

Avec: Fabio Raith , Daniel H O'Donovan , Clara Lemos , Bernard Haendler

Dual targeting of the androgen receptor and PI3K/AKT/mTOR pathways in prostate cancer models improves antitumor efficacy and promotes cell apoptosis.

Molecular oncology

Avec: Tatsuo Sugawara , Ekaterina Nevedomskaya , Simon Heller , Annika Böhme , Ralf Lesche , Oliver von Ahsen , Sylvia Grünewald , Holly M Nguyen , Eva Corey , Simon J Baumgart , Victoria Georgi , Vera Pütter , Amaury Fernández-Montalván , James D Vasta , Matthew B Robers , Dominik Mumberg , Bernard Haendler

Réseau de co-auteurs

Dominik Mumberg 4 collaborations

Ningshu Liu 3 collaborations

Chiara Tarantelli 2 collaborations

Eugenio Gaudio 2 collaborations

Luciano Cascione 2 collaborations

Filippo Spriano 2 collaborations

Alberto J Arribas 2 collaborations

Anastasios Stathis 2 collaborations

Emanuele Zucca 2 collaborations

Francesco Bertoni 2 collaborations

Karl Ziegelbauer 2 collaborations

Dieter Zopf 2 collaborations

Sylvia Grünewald 2 collaborations

Simon Heller 2 collaborations

Annika Böhme 2 collaborations

Ralf Lesche 2 collaborations

Oliver von Ahsen 2 collaborations

Bernard Haendler 2 collaborations

Alfonso García-Valverde 1 collaboration

Jordi Rosell 1 collaboration

Garazi Serna 1 collaboration

Claudia Valverde 1 collaboration

Joan Carles 1 collaboration

Paolo Nuciforo 1 collaboration

Jonathan A Fletcher 1 collaboration

Joaquín Arribas 1 collaboration

César Serrano 1 collaboration

Martin Lange 1 collaboration

Ivo Kwee 1 collaboration

Andrea Rinaldi 1 collaboration

Thibaud Jourdan 1 collaboration

Melanie Berthold 1 collaboration

Andrea Sturz 1 collaboration

Carolyn Sperl 1 collaboration

Francesco Margheriti 1 collaboration

Lorenzo Scalise 1 collaboration

Giuseppe Gritti 1 collaboration

Davide Rossi 1 collaboration

Hung Huynh 1 collaboration

Richard Ong 1 collaboration

Kah Yong Goh 1 collaboration

Liek Yeow Lee 1 collaboration

Florian Puehler 1 collaboration

Arne Scholz 1 collaboration

Sabine Zitzmann-Kolbe 1 collaboration

Alexander Kristian 1 collaboration

Claudia Kamfenkel 1 collaboration

Christine Ellingsen 1 collaboration

Jochen Hilbig 1 collaboration

Mark U Juul 1 collaboration

Jesper Fonslet 1 collaboration

Carsten H Nielsen 1 collaboration

Christoph A Schatz 1 collaboration

Roger M Bjerke 1 collaboration

Alan S Cuthbertson 1 collaboration

Urs B Hagemann 1 collaboration

Giulio Sartori 1 collaboration

Michele Mascia 1 collaboration

Marilia Barreca 1 collaboration

Luca Licenziato 1 collaboration

Gaetanina Golino 1 collaboration

Adele Ferragamo 1 collaboration

Stefano Pileri 1 collaboration

Giovanna Damia 1 collaboration

Antje M Wengner 1 collaboration

Sebastian Bender 1 collaboration

Mélanie Héroult 1 collaboration

Klemens Lustig 1 collaboration

Uwe Thuss 1 collaboration

Christoph Kneip 1 collaboration

Charlotte Kopitz 1 collaboration

Marie-Pierre Collin 1 collaboration

Ulf Boemer 1 collaboration

Stuart Ince 1 collaboration

Peter Ellinghaus 1 collaboration

Holger Hess-Stumpp 1 collaboration

Konrad Klinghammer 1 collaboration

Theresa Eder 1 collaboration

Raik Otto 1 collaboration

Jan-Dirk Raguse 1 collaboration

Andreas Albers 1 collaboration

Andreas Kaufmann 1 collaboration

Ingeborg Tinhofer 1 collaboration

Jens Hoffmann 1 collaboration

Ulrich Keller 1 collaboration

Ulrich Keilholz 1 collaboration

Sarah Glaeske 1 collaboration

Katja Gluske 1 collaboration

Juliane Paul 1 collaboration

Andreas Janzer 1 collaboration

Helge Gottfried Roider 1 collaboration

Anna Montebaur 1 collaboration

Barbara Nicke 1 collaboration

Mátyás Gorjánácz 1 collaboration

Dachuan Huang 1 collaboration

Tammy Linlin Song 1 collaboration

Maarja-Liisa Nairismägi 1 collaboration

Yurike Laurensia 1 collaboration

Wan-Lu Pang 1 collaboration

Daryl Cheah Ming Zhe 1 collaboration

Esther Kam Yin Wong 1 collaboration

Giovani Giovani-Clarest Wijaya 1 collaboration

Jing Tan 1 collaboration

Sze Huey Tan 1 collaboration

Jing-Quan Lim 1 collaboration

Burton Kuan Hui Chia 1 collaboration

Jason Yongsheng Chan 1 collaboration

Tiffany Pooi Ling Tang 1 collaboration

Nagavalli Somasundaram 1 collaboration

Chee Leong Cheng 1 collaboration

Soon Thye Lim 1 collaboration

Choon Kiat Ong 1 collaboration

Fabio Raith 1 collaboration

Daniel H O'Donovan 1 collaboration

Clara Lemos 1 collaboration

Tatsuo Sugawara 1 collaboration

Ekaterina Nevedomskaya 1 collaboration

Holly M Nguyen 1 collaboration

Eva Corey 1 collaboration

Simon J Baumgart 1 collaboration

Victoria Georgi 1 collaboration

Vera Pütter 1 collaboration

Amaury Fernández-Montalván 1 collaboration

James D Vasta 1 collaboration

Matthew B Robers 1 collaboration