Nicol Birsa

Affiliations

Department of Neuromuscular Diseases, UCL Queen Square Institute of Neurology, University College London, London WC1N 3BG, UK.
UK Dementia Research Institute.

Publications (10)

FUS ALS-causative mutations impair FUS autoregulation and splicing factor networks through intron retention.

Nucleic acids research

Avec: Jack Humphrey , Carmelo Milioto , Martha McLaughlin , Agnieszka M Ule , David Robaldo , Andrea B Eberle , Rahel Kräuchi , Matthew Bentham , Anna-Leigh Brown , Seth Jarvis , Cristian Bodo , Maria G Garone , Anny Devoy , Gianni Soraru , Alessandro Rosa , Irene Bozzoni , Elizabeth M C Fisher , Oliver Mühlemann , Giampietro Schiavo , Marc-David Ruepp , Adrian M Isaacs , Vincent Plagnol , Pietro Fratta

Cytoplasmic functions of TDP-43 and FUS and their role in ALS.

Seminars in cell & developmental biology

Avec: Matthew Peter Bentham , Pietro Fratta

TDP-43 loss induces extensive cryptic polyadenylation in ALS/FTD.

bioRxiv : the preprint server for biology

Avec: Sam Bryce-Smith , Anna-Leigh Brown , Puja R Mehta , Francesca Mattedi , Alla Mikheenko , Simone Barattucci , Matteo Zanovello , Dario Dattilo , Matthew Yome , Sarah E Hill , Yue A Qi , Oscar G Wilkins , Kai Sun , Eugeni Ryadnov , Yixuan Wan , Auteur inconnu , Jose Norberto S Vargas , Towfique Raj , Jack Humphrey , Matthew Keuss , Michael Ward , Maria Secrier , Pietro Fratta

C9orf72 arginine-rich dipeptide proteins interact with ribosomal proteins in vivo to induce a toxic translational arrest that is rescued by eIF1A.

Acta neuropathologica

Avec: Thomas G Moens , Teresa Niccoli , Katherine M Wilson , Magda L Atilano , Lauren M Gittings , Benedikt V Holbling , Miranda C Dyson , Annora Thoeng , Jacob Neeves , Idoia Glaria , Lu Yu , Julia Bussmann , Erik Storkebaum , Mercedes Pardo , Jyoti S Choudhary , Pietro Fratta , Linda Partridge , Adrian M Isaacs

FUS-ALS mutants alter FMRP phase separation equilibrium and impair protein translation.

Science advances

Avec: Agnieszka M Ule , Maria Giovanna Garone , Brian Tsang , Francesca Mattedi , P Andrew Chong , Jack Humphrey , Seth Jarvis , Melis Pisiren , Oscar G Wilkins , Micheal L Nosella , Anny Devoy , Cristian Bodo , Rafaela Fernandez de la Fuente , Elizabeth M C Fisher , Alessandro Rosa , Gabriella Viero , Julie D Forman-Kay , Giampietro Schiavo , Pietro Fratta

Loss of neuronal Miro1 disrupts mitophagy and induces hyperactivation of the integrated stress response.

The EMBO journal

Avec: Guillermo López-Doménech , Jack H Howden , Christian Covill-Cooke , Corinne Morfill , Jigna V Patel , Roland Bürli , Damian Crowther , Nicholas J Brandon , Josef T Kittler

Peroxisomal fission is modulated by the mitochondrial Rho-GTPases, Miro1 and Miro2.

EMBO reports

Avec: Christian Covill-Cooke , Viktoriya S Toncheva , James Drew , Guillermo López-Doménech , Josef T Kittler

Travelling Together: A Unifying Pathomechanism for ALS.

Trends in neurosciences

Avec: Pietro Fratta , Andrew P Tosolini , Giampietro Schiavo

A Comparison of Low Read Depth QuantSeq 3' Sequencing to Total RNA-Seq in FUS Mutant Mice.

Frontiers in genetics

Avec: Seth Jarvis , Maria Secrier , Pietro Fratta , Vincent Plagnol

ALS-related FUS mutations alter axon growth in motoneurons and affect HuD/ELAVL4 and FMRP activity.

Communications biology

Avec: Maria Giovanna Garone , Maria Rosito , Federico Salaris , Michela Mochi , Valeria de Turris , Remya R Nair , Thomas J Cunningham , Elizabeth M C Fisher , Mariangela Morlando , Pietro Fratta , Alessandro Rosa

Réseau de co-auteurs

Pietro Fratta 8 collaborations

Jack Humphrey 3 collaborations

Seth Jarvis 3 collaborations

Alessandro Rosa 3 collaborations

Elizabeth M C Fisher 3 collaborations

Giampietro Schiavo 3 collaborations

Agnieszka M Ule 2 collaborations

Anna-Leigh Brown 2 collaborations

Cristian Bodo 2 collaborations

Anny Devoy 2 collaborations

Adrian M Isaacs 2 collaborations

Vincent Plagnol 2 collaborations

Francesca Mattedi 2 collaborations

Oscar G Wilkins 2 collaborations

Maria Secrier 2 collaborations

Maria Giovanna Garone 2 collaborations

Guillermo López-Doménech 2 collaborations

Christian Covill-Cooke 2 collaborations

Josef T Kittler 2 collaborations

Carmelo Milioto 1 collaboration

Martha McLaughlin 1 collaboration

David Robaldo 1 collaboration

Andrea B Eberle 1 collaboration

Rahel Kräuchi 1 collaboration

Matthew Bentham 1 collaboration

Maria G Garone 1 collaboration

Gianni Soraru 1 collaboration

Irene Bozzoni 1 collaboration

Oliver Mühlemann 1 collaboration

Marc-David Ruepp 1 collaboration

Matthew Peter Bentham 1 collaboration

Sam Bryce-Smith 1 collaboration

Puja R Mehta 1 collaboration

Alla Mikheenko 1 collaboration

Simone Barattucci 1 collaboration

Matteo Zanovello 1 collaboration

Dario Dattilo 1 collaboration

Matthew Yome 1 collaboration

Sarah E Hill 1 collaboration

Yue A Qi 1 collaboration

Kai Sun 1 collaboration

Eugeni Ryadnov 1 collaboration

Yixuan Wan 1 collaboration

None None 1 collaboration

Jose Norberto S Vargas 1 collaboration

Towfique Raj 1 collaboration

Matthew Keuss 1 collaboration

Michael Ward 1 collaboration

Thomas G Moens 1 collaboration

Teresa Niccoli 1 collaboration

Katherine M Wilson 1 collaboration

Magda L Atilano 1 collaboration

Lauren M Gittings 1 collaboration

Benedikt V Holbling 1 collaboration

Miranda C Dyson 1 collaboration

Annora Thoeng 1 collaboration

Jacob Neeves 1 collaboration

Idoia Glaria 1 collaboration

Lu Yu 1 collaboration

Julia Bussmann 1 collaboration

Erik Storkebaum 1 collaboration

Mercedes Pardo 1 collaboration

Jyoti S Choudhary 1 collaboration

Linda Partridge 1 collaboration

Brian Tsang 1 collaboration

P Andrew Chong 1 collaboration

Melis Pisiren 1 collaboration

Micheal L Nosella 1 collaboration

Rafaela Fernandez de la Fuente 1 collaboration

Gabriella Viero 1 collaboration

Julie D Forman-Kay 1 collaboration

Jack H Howden 1 collaboration

Corinne Morfill 1 collaboration

Jigna V Patel 1 collaboration

Roland Bürli 1 collaboration

Damian Crowther 1 collaboration

Nicholas J Brandon 1 collaboration

Viktoriya S Toncheva 1 collaboration

James Drew 1 collaboration

Andrew P Tosolini 1 collaboration

Maria Rosito 1 collaboration

Federico Salaris 1 collaboration

Michela Mochi 1 collaboration

Valeria de Turris 1 collaboration

Remya R Nair 1 collaboration

Thomas J Cunningham 1 collaboration

Mariangela Morlando 1 collaboration