Mikhail Spivakov

Affiliations

Nuclear Dynamics Programme, Babraham Institute, Cambridge, UK. mikhail.spivakov@lms.mrc.ac.uk.
Functional Gene Control Group, MRC London Institute of Medical Sciences (LMS), London, UK. mikhail.spivakov@lms.mrc.ac.uk.
Institute of Clinical Sciences, Imperial College Faculty of Medicine, London, UK. mikhail.spivakov@lms.mrc.ac.uk.

ORCID: 0000-0002-0383-3943

Publications (13)

Genetic perturbation of PU.1 binding and chromatin looping at neutrophil enhancers associates with autoimmune disease.

Nature communications

Avec: Stephen Watt , Louella Vasquez , Klaudia Walter , Alice L Mann , Kousik Kundu , Lu Chen , Ying Sims , Simone Ecker , Frances Burden , Samantha Farrow , Ben Farr , Valentina Iotchkova , Heather Elding , Daniel Mead , Manuel Tardaguila , Hannes Ponstingl , David Richardson , Avik Datta , Paul Flicek , Laura Clarke , Kate Downes , Tomi Pastinen , Peter Fraser , Mattia Frontini , Biola-Maria Javierre , Nicole Soranzo

TOP1 inhibition therapy protects against SARS-CoV-2-induced lethal inflammation.

Cell

Avec: Jessica Sook Yuin Ho , Bobo Wing-Yee Mok , Laura Campisi , Tristan Jordan , Soner Yildiz , Sreeja Parameswaran , Joseph A Wayman , Natasha N Gaudreault , David A Meekins , Sabarish V Indran , Igor Morozov , Jessie D Trujillo , Yesai S Fstkchyan , Raveen Rathnasinghe , Zeyu Zhu , Simin Zheng , Nan Zhao , Kris White , Helen Ray-Jones , Valeriya Malysheva , Michiel J Thiecke , Siu-Ying Lau , Honglian Liu , Anna Junxia Zhang , Andrew Chak-Yiu Lee , Wen-Chun Liu , Sonia Jangra , Alba Escalera , Teresa Aydillo , Betsaida Salom Melo , Ernesto Guccione , Robert Sebra , Elaine Shum , Jan Bakker , David A Kaufman , Andre L Moreira , Mariano Carossino , Udeni B R Balasuriya , Minji Byun , Randy A Albrecht , Michael Schotsaert , Adolfo Garcia-Sastre , Sumit K Chanda , Emily R Miraldi , Anand D Jeyasekharan , Benjamin R TenOever , Matthew T Weirauch , Sven Heinz , Honglin Chen , Christopher Benner , Juergen A Richt , Ivan Marazzi

Cellular mechanisms of oligoclonal vascular smooth muscle cell expansion in cardiovascular disease.

Cardiovascular research

Avec: Matt D Worssam , Jordi Lambert , Sebnem Oc , James C K Taylor , Annabel L Taylor , Lina Dobnikar , Joel Chappell , Jennifer L Harman , Nichola L Figg , Alison Finigan , Kirsty Foote , Anna K Uryga , Martin R Bennett , Helle F Jørgensen

Cohesin-Dependent and -Independent Mechanisms Mediate Chromosomal Contacts between Promoters and Enhancers.

Cell reports

Avec: Michiel J Thiecke , Gordana Wutz , Matthias Muhar , Wen Tang , Stephen Bevan , Valeriya Malysheva , Roman Stocsits , Tobias Neumann , Johannes Zuber , Peter Fraser , Stefan Schoenfelder , Jan-Michael Peters ,

Detecting chromosomal interactions in Capture Hi-C data with CHiCAGO and companion tools.

Nature protocols

Avec: Paula Freire-Pritchett , Helen Ray-Jones , Monica Della Rosa , Chris Q Eijsbouts , William R Orchard , Steven W Wingett , Chris Wallace , Jonathan Cairns , Valeriya Malysheva

Brief encounters: The relationship between enhancer proximity and gene expression.

Developmental cell

Avec: Helen Ray-Jones ,

Prioritisation of Candidate Genes Underpinning COVID-19 Host Genetic Traits Based on High-Resolution 3D Chromosomal Topology.

Frontiers in genetics

Avec: Michiel J Thiecke , Emma J Yang , Oliver S Burren , Helen Ray-Jones ,

Network-based prioritization and validation of regulators of vascular smooth muscle cell proliferation in disease.

Nature cardiovascular research

Avec: Jordi Lambert , Sebnem Oc , Matthew D Worssam , Daniel Häußler , Charles U Solomon , Nichola L Figg , Ruby Baxter , Maria Imaz , James C K Taylor , Kirsty Foote , Alison Finigan , Krishnaa T Mahbubani , Tom R Webb , Shu Ye , Martin R Bennett , Achim Krüger , Helle F Jørgensen

Functional effects of variation in transcription factor binding highlight long-range gene regulation by epromoters.

Nucleic acids research

Avec: Joanna Mitchelmore , Nastasiya F Grinberg , Chris Wallace ,

Topoisomerase 1 inhibition therapy protects against SARS-CoV-2-induced inflammation and death in animal models.

bioRxiv : the preprint server for biology

Avec: Jessica Sook Yuin Ho , Bobo Wing-Yee Mok , Laura Campisi , Tristan Jordan , Soner Yildiz , Sreeja Parameswaran , Joseph A Wayman , Natasha N Gaudreault , David A Meekins , Sabarish V Indran , Igor Morozov , Jessie D Trujillo , Yesai S Fstkchyan , Raveen Rathnasinghe , Zeyu Zhu , Simin Zheng , Nan Zhao , Kris White , Helen Ray-Jones , Valeriya Malysheva , Michiel J Thiecke , Siu-Ying Lau , Honglian Liu , Anna Junxia Zhang , Andrew Chak-Yiu Lee , Wen-Chun Liu , Teresa Aydillo , Betsaida Salom Melo , Ernesto Guccione , Robert Sebra , Elaine Shum , Jan Bakker , David A Kaufman , Andre L Moreira , Mariano Carossino , Udeni B R Balasuriya , Minji Byun , Emily R Miraldi , Randy A Albrecht , Michael Schotsaert , Adolfo Garcia-Sastre , Sumit K Chanda , Anand D Jeyasekharan , Benjamin R TenOever , Matthew T Weirauch , Sven Heinz , Honglin Chen , Christopher Benner , Juergen A Richt , Ivan Marazzi

Network-based prioritization and validation of regulators of vascular smooth muscle cell proliferation in disease.

Nature cardiovascular research

Avec: Jordi Lambert , Sebnem Oc , Matthew D Worssam , Daniel Häußler , Charles U Solomon , Nichola L Figg , Ruby Baxter , Maria Imaz , James C K Taylor , Kirsty Foote , Alison Finigan , Krishnaa T Mahbubani , Tom R Webb , Shu Ye , Martin R Bennett , Achim Krüger , Helle F Jørgensen

Chicdiff: a computational pipeline for detecting differential chromosomal interactions in Capture Hi-C data.

Bioinformatics (Oxford, England)

Avec: Jonathan Cairns , William R Orchard , Valeriya Malysheva ,

Transcriptional enhancers and their communication with gene promoters.

Cellular and molecular life sciences : CMLS

Avec: Helen Ray-Jones ,

Réseau de co-auteurs

Helen Ray-Jones 6 collaborations

Valeriya Malysheva 5 collaborations

Michiel J Thiecke 4 collaborations

Jordi Lambert 3 collaborations

Sebnem Oc 3 collaborations

James C K Taylor 3 collaborations

Nichola L Figg 3 collaborations

Alison Finigan 3 collaborations

Kirsty Foote 3 collaborations

Martin R Bennett 3 collaborations

Helle F Jørgensen 3 collaborations

Peter Fraser 2 collaborations

Jessica Sook Yuin Ho 2 collaborations

Bobo Wing-Yee Mok 2 collaborations

Laura Campisi 2 collaborations

Tristan Jordan 2 collaborations

Soner Yildiz 2 collaborations

Sreeja Parameswaran 2 collaborations

Joseph A Wayman 2 collaborations

Natasha N Gaudreault 2 collaborations

David A Meekins 2 collaborations

Sabarish V Indran 2 collaborations

Igor Morozov 2 collaborations

Jessie D Trujillo 2 collaborations

Yesai S Fstkchyan 2 collaborations

Raveen Rathnasinghe 2 collaborations

Zeyu Zhu 2 collaborations

Simin Zheng 2 collaborations

Nan Zhao 2 collaborations

Kris White 2 collaborations

Siu-Ying Lau 2 collaborations

Honglian Liu 2 collaborations

Anna Junxia Zhang 2 collaborations

Andrew Chak-Yiu Lee 2 collaborations

Wen-Chun Liu 2 collaborations

Teresa Aydillo 2 collaborations

Betsaida Salom Melo 2 collaborations

Ernesto Guccione 2 collaborations

Robert Sebra 2 collaborations

Elaine Shum 2 collaborations

Jan Bakker 2 collaborations

David A Kaufman 2 collaborations

Andre L Moreira 2 collaborations

Mariano Carossino 2 collaborations

Udeni B R Balasuriya 2 collaborations

Minji Byun 2 collaborations

Randy A Albrecht 2 collaborations

Michael Schotsaert 2 collaborations

Adolfo Garcia-Sastre 2 collaborations

Sumit K Chanda 2 collaborations

Emily R Miraldi 2 collaborations

Anand D Jeyasekharan 2 collaborations

Benjamin R TenOever 2 collaborations

Matthew T Weirauch 2 collaborations

Sven Heinz 2 collaborations

Honglin Chen 2 collaborations

Christopher Benner 2 collaborations

Juergen A Richt 2 collaborations

Ivan Marazzi 2 collaborations

William R Orchard 2 collaborations

Chris Wallace 2 collaborations

Jonathan Cairns 2 collaborations

Matthew D Worssam 2 collaborations

Daniel Häußler 2 collaborations

Charles U Solomon 2 collaborations

Ruby Baxter 2 collaborations

Maria Imaz 2 collaborations

Krishnaa T Mahbubani 2 collaborations

Tom R Webb 2 collaborations

Shu Ye 2 collaborations

Achim Krüger 2 collaborations

Stephen Watt 1 collaboration

Louella Vasquez 1 collaboration

Klaudia Walter 1 collaboration

Alice L Mann 1 collaboration

Kousik Kundu 1 collaboration

Lu Chen 1 collaboration

Ying Sims 1 collaboration

Simone Ecker 1 collaboration

Frances Burden 1 collaboration

Samantha Farrow 1 collaboration

Ben Farr 1 collaboration

Valentina Iotchkova 1 collaboration

Heather Elding 1 collaboration

Daniel Mead 1 collaboration

Manuel Tardaguila 1 collaboration

Hannes Ponstingl 1 collaboration

David Richardson 1 collaboration

Avik Datta 1 collaboration

Paul Flicek 1 collaboration

Laura Clarke 1 collaboration

Kate Downes 1 collaboration

Tomi Pastinen 1 collaboration

Mattia Frontini 1 collaboration

Biola-Maria Javierre 1 collaboration

Nicole Soranzo 1 collaboration

Sonia Jangra 1 collaboration

Alba Escalera 1 collaboration

Matt D Worssam 1 collaboration

Annabel L Taylor 1 collaboration

Lina Dobnikar 1 collaboration

Joel Chappell 1 collaboration

Jennifer L Harman 1 collaboration

Anna K Uryga 1 collaboration

Gordana Wutz 1 collaboration

Matthias Muhar 1 collaboration

Wen Tang 1 collaboration

Stephen Bevan 1 collaboration

Roman Stocsits 1 collaboration

Tobias Neumann 1 collaboration

Johannes Zuber 1 collaboration

Stefan Schoenfelder 1 collaboration

Jan-Michael Peters 1 collaboration

Paula Freire-Pritchett 1 collaboration

Monica Della Rosa 1 collaboration

Chris Q Eijsbouts 1 collaboration

Steven W Wingett 1 collaboration

Emma J Yang 1 collaboration

Oliver S Burren 1 collaboration

Joanna Mitchelmore 1 collaboration

Nastasiya F Grinberg 1 collaboration