Michael S Malamas

Affiliations

Center for Drug Discovery and Department of Chemistry and Chemical Biology and Pharmaceutical Sciences, Northeastern University, Boston, MA 02155, USA. Electronic address: m.malamas@northeastern.edu.

Publications (13)

Piperidine and piperazine inhibitors of fatty acid amide hydrolase targeting excitotoxic pathology.

Bioorganic & medicinal chemistry

Avec: Manjunath Lamani , Shrouq I Farah , Vidyanand G Shukla , Michael F Almeida , Catherine M Weerts , Joseph Anderson , JodiAnne T Wood , Karen L G Farizatto , Ben A Bahr , Alexandros Makriyannis

N-Acylethanolamine Acid Amidase Inhibition Potentiates Morphine Analgesia and Delays the Development of Tolerance.

Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics

Avec: Mauro Congiu , Laura Micheli , Michele Santoni , Claudia Sagheddu , Anna Lisa Muntoni , Alexandros Makriyannis , Carla Ghelardini , Lorenzo Di Cesare Mannelli , Marco Pistis

Synthesis and evaluation of potent and selective MGL inhibitors as a glaucoma treatment.

Bioorganic & medicinal chemistry

Avec: Shakiru O Alapafuja , Vidyanand Shukla , Alexander Zvonok , Sally Miller , Laura Daily , Girija Rajarshi , Christina Yume Miyabe , Honrao Chandrashekhar , JodiAnne Wood , Sergiy Tyukhtenko , Alex Straiker , Alexandros Makriyannis

Inhibition of N-acylethanolamine acid amidase reduces nicotine-induced dopamine activation and reward.

Neuropharmacology

Avec: Claudia Sagheddu , Maria Scherma , Mauro Congiu , Paola Fadda , Gianfranca Carta , Sebastiano Banni , JodiAnne T Wood , Alexandros Makriyannis , Marco Pistis

The endocannabinoid 2-arachidonoylglycerol and dual ABHD6/MAGL enzyme inhibitors display neuroprotective and anti-inflammatory actions in the in vivo retinal model of AMPA excitotoxicity.

Neuropharmacology

Avec: Despina Kokona , Dimitris Spyridakos , Manolis Tzatzarakis , Sofia Papadogkonaki , Eirini Filidou , Konstantinos I Arvanitidis , George Kolios , Manjunath Lamani , Alexandros Makriyannis , Kyriaki Thermos

Design and Synthesis of Highly Potent and Specific ABHD6 Inhibitors.

ChemMedChem

Avec: Manjunath Lamani , Shrouq I Farah , Khadijah A Mohammad , Christina Yume Miyabe , Girija Rajarshi , Simiao Wu , Nikolai Zvonok , Honrao Chandrashekhar , JodiAnne Wood , Alexandros Makriyannis

The novel cannabinoid CB

British journal of pharmacology

Avec: Sean B Ogden , Alexandros Makriyannis , Lisa A Eckel

N-acylethanolamine-hydrolysing acid amidase: A new potential target to treat paclitaxel-induced neuropathy.

European journal of pain (London, England)

Avec: Wisam Toma , Martial Caillaud , Nipa H Patel , Tammy H Tran , Giulia Donvito , Jane Roberts , Deniz Bagdas , Asti Jackson , Aron Lichtman , David A Gewirtz , Alexandros Makriyannis , M Imad Damaj

Inhibition of triple negative breast cancer-associated inflammation, tumor growth and brain colonization by targeting monoacylglycerol lipase.

Scientific reports

Avec: Othman Benchama , Sergiy Tyukhtenko , Mark K Williams , Alexandros Makriyannis , Hava Karsenty Avraham

Investigating the Effects of Exogenous and Endogenous 2-Arachidonoylglycerol on Retinal CB1 Cannabinoid Receptors and Reactive Microglia in Naive and Diseased Retina.

International journal of molecular sciences

Avec: Sofia Papadogkonaki , Dimitris Spyridakos , Emmanouela Lapokonstantaki , Nikos Chaniotakis , Alexandros Makriyannis , Kyriaki Thermos

Endocannabinoid metabolism and transport as targets to regulate intraocular pressure.

Experimental eye research

Avec: Sally Miller , Laura Daily , Vijai Dharla , Juerg Gertsch , Iwao Ojima , Martin Kaczocha , Daisuke Ogasawara , Alex Straiker

Design and synthesis of cyanamides as potent and selective N-acylethanolamine acid amidase inhibitors.

Bioorganic & medicinal chemistry

Avec: Shrouq I Farah , Manjunath Lamani , Dimitrios N Pelekoudas , Nicholas Thomas Perry , Girija Rajarshi , Christina Yume Miyabe , Honrao Chandrashekhar , Jay West , Spiro Pavlopoulos , Alexandros Makriyannis

Inhibition of triple negative breast cancer-associated inflammation and progression by N- acylethanolamine acid amide hydrolase (NAAA).

Scientific reports

Avec: Othman Benchama , Kulkarni Praveen , Elizabeth C Ethier , Mark K Williams , Alexandros Makriyannis , Hava Karsenty Avraham

Réseau de co-auteurs

Alexandros Makriyannis 12 collaborations

Manjunath Lamani 4 collaborations

Shrouq I Farah 3 collaborations

Girija Rajarshi 3 collaborations

Christina Yume Miyabe 3 collaborations

Honrao Chandrashekhar 3 collaborations

JodiAnne T Wood 2 collaborations

Mauro Congiu 2 collaborations

Claudia Sagheddu 2 collaborations

Marco Pistis 2 collaborations

Sally Miller 2 collaborations

Laura Daily 2 collaborations

JodiAnne Wood 2 collaborations

Sergiy Tyukhtenko 2 collaborations

Alex Straiker 2 collaborations

Dimitris Spyridakos 2 collaborations

Sofia Papadogkonaki 2 collaborations

Kyriaki Thermos 2 collaborations

Othman Benchama 2 collaborations

Mark K Williams 2 collaborations

Hava Karsenty Avraham 2 collaborations

Vidyanand G Shukla 1 collaboration

Michael F Almeida 1 collaboration

Catherine M Weerts 1 collaboration

Joseph Anderson 1 collaboration

Karen L G Farizatto 1 collaboration

Ben A Bahr 1 collaboration

Laura Micheli 1 collaboration

Michele Santoni 1 collaboration

Anna Lisa Muntoni 1 collaboration

Carla Ghelardini 1 collaboration

Lorenzo Di Cesare Mannelli 1 collaboration

Shakiru O Alapafuja 1 collaboration

Vidyanand Shukla 1 collaboration

Alexander Zvonok 1 collaboration

Maria Scherma 1 collaboration

Paola Fadda 1 collaboration

Gianfranca Carta 1 collaboration

Sebastiano Banni 1 collaboration

Despina Kokona 1 collaboration

Manolis Tzatzarakis 1 collaboration

Eirini Filidou 1 collaboration

Konstantinos I Arvanitidis 1 collaboration

George Kolios 1 collaboration

Khadijah A Mohammad 1 collaboration

Simiao Wu 1 collaboration

Nikolai Zvonok 1 collaboration

Sean B Ogden 1 collaboration

Lisa A Eckel 1 collaboration

Wisam Toma 1 collaboration

Martial Caillaud 1 collaboration

Nipa H Patel 1 collaboration

Tammy H Tran 1 collaboration

Giulia Donvito 1 collaboration

Jane Roberts 1 collaboration

Deniz Bagdas 1 collaboration

Asti Jackson 1 collaboration

Aron Lichtman 1 collaboration

David A Gewirtz 1 collaboration

M Imad Damaj 1 collaboration

Emmanouela Lapokonstantaki 1 collaboration

Nikos Chaniotakis 1 collaboration

Vijai Dharla 1 collaboration

Juerg Gertsch 1 collaboration

Iwao Ojima 1 collaboration

Martin Kaczocha 1 collaboration

Daisuke Ogasawara 1 collaboration

Dimitrios N Pelekoudas 1 collaboration

Nicholas Thomas Perry 1 collaboration

Jay West 1 collaboration

Spiro Pavlopoulos 1 collaboration

Kulkarni Praveen 1 collaboration

Elizabeth C Ethier 1 collaboration