Michael J Delves

Affiliations

London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK.

Publications (14)

The antimalarial screening landscape-looking beyond the asexual blood stage.

Current opinion in chemical biology

Avec: Sabrina Yahiya , Ainoa Rueda-Zubiaurre , Matthew J Fuchter , Jake Baum

A novel class of sulphonamides potently block malaria transmission by targeting a Plasmodium vacuole membrane protein.

Disease models & mechanisms

Avec: Sabrina Yahiya , Charlie N Saunders , Sarah Hassan , Ursula Straschil , Oliver J Fischer , Ainoa Rueda-Zubiaurre , Silvia Haase , Gema Vizcay-Barrena , Mufuliat Toyin Famodimu , Sarah Jordan , Edward W Tate , Anna Barnard , Matthew J Fuchter , Jake Baum

A Pyridyl-Furan Series Developed from the Open Global Health Library Block Red Blood Cell Invasion and Protein Trafficking in

ACS infectious diseases

Avec: Dawson B Ling , William Nguyen , Oliver Looker , Zahra Razook , Kirsty McCann , Alyssa E Barry , Christian Scheurer , Sergio Wittlin , Mufuliat Toyin Famodimu , Hayley E Bullen , Brendan S Crabb , Brad E Sleebs , Paul R Gilson

Optimisation-based modelling for explainable lead discovery in malaria.

Artificial intelligence in medicine

Avec: Yutong Li , Jonathan Cardoso-Silva , John M Kelly , Nicholas Furnham , Lazaros G Papageorgiou , Sophia Tsoka

Screen of traditional soup broths with reported antipyretic activity towards the discovery of potential antimalarials.

Archives of disease in childhood

Avec: Auteur inconnu , Ursula Straschil , Kathrin Witmer , Stephen D Marks , Jake Baum

The Novel bis-1,2,4-Triazine MIPS-0004373 Demonstrates Rapid and Potent Activity against All Blood Stages of the Malaria Parasite.

Antimicrobial agents and chemotherapy

Avec: Katherine M Ellis , Leonardo Lucantoni , Marina Chavchich , Matthew Abraham , Amanda De Paoli , Madeline R Luth , Anne-Marie Zeeman , Fernando Sánchez-Román Terán , Ursula Straschil , Jake Baum , Clemens H M Kocken , Stuart A Ralph , Elizabeth A Winzeler , Vicky M Avery , Michael D Edstein , Jonathan B Baell , Darren J Creek

Aryl amino acetamides prevent Plasmodium falciparum ring development via targeting the lipid-transfer protein PfSTART1.

Nature communications

Avec: Madeline G Dans , Coralie Boulet , Gabrielle M Watson , William Nguyen , Jerzy M Dziekan , Cindy Evelyn , Kitsanapong Reaksudsan , Somya Mehra , Zahra Razook , Niall D Geoghegan , Michael J Mlodzianoski , Christopher Dean Goodman , Dawson B Ling , Thorey K Jonsdottir , Joshua Tong , Mufuliat Toyin Famodimu , Mojca Kristan , Harry Pollard , Lindsay B Stewart , Luke Brandner-Garrod , Colin J Sutherland , Geoffrey I McFadden , Alyssa E Barry , Brendan S Crabb , Tania F de Koning-Ward , Kelly L Rogers , Alan F Cowman , Wai-Hong Tham , Brad E Sleebs , Paul R Gilson

Exploration and characterization of the antimalarial activity of cyclopropyl carboxamides that target the mitochondrial protein, cytochrome b.

European journal of medicinal chemistry

Avec: Jon Kyle Awalt , Wenyin Su , William Nguyen , Katie Loi , Kate E Jarman , Jocelyn S Penington , Saishyam Ramesh , Kate J Fairhurst , Tomas Yeo , Heekuk Park , Anne-Catrin Uhlemann , Bikash Chandra Maity , Nirupam De , Partha Mukherjee , Arnish Chakraborty , Alisje Churchyard , Mufuliat T Famodimu , Jake Baum , Nimisha Mittal , Elizabeth A Winzeler , Anthony T Papenfuss , Mrittika Chowdury , Tania F de Koning-Ward , Alexander G Maier , Giel G van Dooren , Delphine Baud , Stephen Brand , David A Fidock , Paul F Jackson , Alan F Cowman , Madeline G Dans , Brad E Sleebs

Transmission of Artemisinin-Resistant Malaria Parasites to Mosquitoes under Antimalarial Drug Pressure.

Antimicrobial agents and chemotherapy

Avec: Kathrin Witmer , Farah A Dahalan , Sabrina Yahiya , Oliver J Watson , Ursula Straschil , Darunee Chiwcharoen , Boodtee Sornboon , Sasithon Pukrittayakamee , Richard D Pearson , Virginia M Howick , Mara K N Lawniczak , Nicholas J White , Arjen M Dondorp , Lucy C Okell , Kesinee Chotivanich , Andrea Ruecker , Jake Baum

The antimalarial efficacy and mechanism of resistance of the novel chemotype DDD01034957.

Scientific reports

Avec: Celia Miguel-Blanco , James M Murithi , Ernest Diez Benavente , Fiona Angrisano , Katarzyna A Sala , Donelly A van Schalkwyk , Manu Vanaerschot , Frank Schwach , Matthew J Fuchter , Oliver Billker , Colin J Sutherland , Susana G Campino , Taane G Clark , Andrew M Blagborough , David A Fidock , Esperanza Herreros , Francisco Javier Gamo , Jake Baum ,

Structure-Activity Relationship Studies of a Novel Class of Transmission Blocking Antimalarials Targeting Male Gametes.

Journal of medicinal chemistry

Avec: Ainoa Rueda-Zubiaurre , Sabrina Yahiya , Oliver J Fischer , Xiaojun Hu , Charlie N Saunders , Sachi Sharma , Ursula Straschil , Junting Shen , Edward W Tate , Jake Baum , Anna Barnard , Matthew J Fuchter

Property and Activity Refinement of Dihydroquinazolinone-3-carboxamides as Orally Efficacious Antimalarials that Target PfATP4.

Journal of medicinal chemistry

Avec: Trent D Ashton , Petar P S Calic , Madeline G Dans , Zi Kang Ooi , Qingmiao Zhou , Josephine Palandri , Katie Loi , Kate E Jarman , Deyun Qiu , Adele M Lehane , Bikash Chandra Maity , Nirupam De , Carlo Giannangelo , Christopher A MacRaild , Darren J Creek , Emma Y Mao , Maria R Gancheva , Danny W Wilson , Mrittika Chowdury , Tania F de Koning-Ward , Mufuliat T Famodimu , Harry Pollard , Colin J Sutherland , Delphine Baud , Stephen Brand , Paul F Jackson , Alan F Cowman , Brad E Sleebs

Lactam Truncation Yields a Dihydroquinazolinone Scaffold with Potent Antimalarial Activity that Targets PfATP4.

ChemMedChem

Avec: Trent D Ashton , Petar P S Calic , Madeline G Dans , Zi Kang Ooi , Qingmiao Zhou , Katie Loi , Kate E Jarman , Josephine Palandri , Deyun Qiu , Adele M Lehane , Bikash Maity , Nirupam De , Mufuliat T Famodimu , Emma Y Mao , Maria R Gancheva , Danny W Wilson , Mrittika Chowdury , Tania F de Koning-Ward , Delphine Baud , Stephen Brand , Paul F Jackson , Alan F Cowman , Brad E Sleebs

Machine learning-based phenotypic imaging to characterise the targetable biology of Plasmodium falciparum male gametocytes for the development of transmission-blocking antimalarials.

PLoS pathogens

Avec: Oleksiy Tsebriy , Andrii Khomiak , Celia Miguel-Blanco , Penny C Sparkes , Maurizio Gioli , Marco Santelli , Edgar Whitley , Francisco-Javier Gamo ,

Réseau de co-auteurs

Jake Baum 8 collaborations

Ursula Straschil 5 collaborations

Brad E Sleebs 5 collaborations

Sabrina Yahiya 4 collaborations

Matthew J Fuchter 4 collaborations

Madeline G Dans 4 collaborations

Tania F de Koning-Ward 4 collaborations

Alan F Cowman 4 collaborations

Ainoa Rueda-Zubiaurre 3 collaborations

Mufuliat Toyin Famodimu 3 collaborations

William Nguyen 3 collaborations

Colin J Sutherland 3 collaborations

Katie Loi 3 collaborations

Kate E Jarman 3 collaborations

Nirupam De 3 collaborations

Mufuliat T Famodimu 3 collaborations

Mrittika Chowdury 3 collaborations

Delphine Baud 3 collaborations

Stephen Brand 3 collaborations

Paul F Jackson 3 collaborations

Charlie N Saunders 2 collaborations

Oliver J Fischer 2 collaborations

Edward W Tate 2 collaborations

Anna Barnard 2 collaborations

Dawson B Ling 2 collaborations

Zahra Razook 2 collaborations

Alyssa E Barry 2 collaborations

Brendan S Crabb 2 collaborations

Paul R Gilson 2 collaborations

Kathrin Witmer 2 collaborations

Elizabeth A Winzeler 2 collaborations

Darren J Creek 2 collaborations

Harry Pollard 2 collaborations

Bikash Chandra Maity 2 collaborations

David A Fidock 2 collaborations

Celia Miguel-Blanco 2 collaborations

Trent D Ashton 2 collaborations

Petar P S Calic 2 collaborations

Zi Kang Ooi 2 collaborations

Qingmiao Zhou 2 collaborations

Josephine Palandri 2 collaborations

Deyun Qiu 2 collaborations

Adele M Lehane 2 collaborations

Emma Y Mao 2 collaborations

Maria R Gancheva 2 collaborations

Danny W Wilson 2 collaborations

Sarah Hassan 1 collaboration

Silvia Haase 1 collaboration

Gema Vizcay-Barrena 1 collaboration

Sarah Jordan 1 collaboration

Oliver Looker 1 collaboration

Kirsty McCann 1 collaboration

Christian Scheurer 1 collaboration

Sergio Wittlin 1 collaboration

Hayley E Bullen 1 collaboration

Yutong Li 1 collaboration

Jonathan Cardoso-Silva 1 collaboration

John M Kelly 1 collaboration

Nicholas Furnham 1 collaboration

Lazaros G Papageorgiou 1 collaboration

Sophia Tsoka 1 collaboration

None None 1 collaboration

Stephen D Marks 1 collaboration

Katherine M Ellis 1 collaboration

Leonardo Lucantoni 1 collaboration

Marina Chavchich 1 collaboration

Matthew Abraham 1 collaboration

Amanda De Paoli 1 collaboration

Madeline R Luth 1 collaboration

Anne-Marie Zeeman 1 collaboration

Fernando Sánchez-Román Terán 1 collaboration

Clemens H M Kocken 1 collaboration

Stuart A Ralph 1 collaboration

Vicky M Avery 1 collaboration

Michael D Edstein 1 collaboration

Jonathan B Baell 1 collaboration

Coralie Boulet 1 collaboration

Gabrielle M Watson 1 collaboration

Jerzy M Dziekan 1 collaboration

Cindy Evelyn 1 collaboration

Kitsanapong Reaksudsan 1 collaboration

Somya Mehra 1 collaboration

Niall D Geoghegan 1 collaboration

Michael J Mlodzianoski 1 collaboration

Christopher Dean Goodman 1 collaboration

Thorey K Jonsdottir 1 collaboration

Joshua Tong 1 collaboration

Mojca Kristan 1 collaboration

Lindsay B Stewart 1 collaboration

Luke Brandner-Garrod 1 collaboration

Geoffrey I McFadden 1 collaboration

Kelly L Rogers 1 collaboration

Wai-Hong Tham 1 collaboration

Jon Kyle Awalt 1 collaboration

Wenyin Su 1 collaboration

Jocelyn S Penington 1 collaboration

Saishyam Ramesh 1 collaboration

Kate J Fairhurst 1 collaboration

Tomas Yeo 1 collaboration

Heekuk Park 1 collaboration

Anne-Catrin Uhlemann 1 collaboration

Partha Mukherjee 1 collaboration

Arnish Chakraborty 1 collaboration

Alisje Churchyard 1 collaboration

Nimisha Mittal 1 collaboration

Anthony T Papenfuss 1 collaboration

Alexander G Maier 1 collaboration

Giel G van Dooren 1 collaboration

Farah A Dahalan 1 collaboration

Oliver J Watson 1 collaboration

Darunee Chiwcharoen 1 collaboration

Boodtee Sornboon 1 collaboration

Sasithon Pukrittayakamee 1 collaboration

Richard D Pearson 1 collaboration

Virginia M Howick 1 collaboration

Mara K N Lawniczak 1 collaboration

Nicholas J White 1 collaboration

Arjen M Dondorp 1 collaboration

Lucy C Okell 1 collaboration

Kesinee Chotivanich 1 collaboration

Andrea Ruecker 1 collaboration

James M Murithi 1 collaboration

Ernest Diez Benavente 1 collaboration

Fiona Angrisano 1 collaboration

Katarzyna A Sala 1 collaboration

Donelly A van Schalkwyk 1 collaboration

Manu Vanaerschot 1 collaboration

Frank Schwach 1 collaboration

Oliver Billker 1 collaboration

Susana G Campino 1 collaboration

Taane G Clark 1 collaboration

Andrew M Blagborough 1 collaboration

Esperanza Herreros 1 collaboration

Francisco Javier Gamo 1 collaboration

Xiaojun Hu 1 collaboration

Sachi Sharma 1 collaboration

Junting Shen 1 collaboration

Carlo Giannangelo 1 collaboration

Christopher A MacRaild 1 collaboration

Bikash Maity 1 collaboration

Oleksiy Tsebriy 1 collaboration

Andrii Khomiak 1 collaboration

Penny C Sparkes 1 collaboration

Maurizio Gioli 1 collaboration

Marco Santelli 1 collaboration

Edgar Whitley 1 collaboration

Francisco-Javier Gamo 1 collaboration