Matthias Hinterndorfer

Affiliations

CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria.

Publications (12)

Discovery of a DCAF11-dependent cyanoacrylamide-containing covalent degrader of BET-proteins.

Bioorganic & medicinal chemistry letters

Avec: Gary Tin , Marko Cigler , Kevin D Dong , Hana Imrichova , Steven P Gygi , Georg E Winter

Discovery of a Drug-like, Natural Product-Inspired DCAF11 Ligand Chemotype.

Nature communications

Avec: Gang Xue , Jianing Xie , Marko Cigler , Lara Dötsch , Hana Imrichova , Philipp Lampe , Xiufen Cheng , Soheila Rezaei Adariani , Georg E Winter , Herbert Waldmann

Alkylamine-tethered molecules recruit FBXO22 for targeted protein degradation.

Nature communications

Avec: Chrysanthi Kagiou , Jose A Cisneros , Jakob Farnung , Joanna Liwocha , Fabian Offensperger , Kevin Dong , Ka Yang , Gary Tin , Christina S Horstmann , Joao A Paulo , Natalie S Scholes , Juan Sanchez Avila , Michaela Fellner , Florian Andersch , J Thomas Hannich , Johannes Zuber , Stefan Kubicek , Steven P Gygi , Brenda A Schulman , Georg E Winter

Integrative analysis of pooled CRISPR genetic screens using MAGeCKFlute.

Nature protocols

Avec: Binbin Wang , Mei Wang , Wubing Zhang , Tengfei Xiao , Chen-Hao Chen , Alexander Wu , Feizhen Wu , Nicole Traugh , Xiaoqing Wang , Ziyi Li , Shenglin Mei , Yingbo Cui , Sailing Shi , Jesse Jonathan Lipp , Johannes Zuber , Myles Brown , Wei Li , X Shirley Liu

AKIRIN2 controls the nuclear import of proteasomes in vertebrates.

Nature

Avec: Melanie de Almeida , Hanna Brunner , Irina Grishkovskaya , Kashish Singh , Alexander Schleiffer , Julian Jude , Sumit Deswal , Robert Kalis , Milica Vunjak , Thomas Lendl , Richard Imre , Elisabeth Roitinger , Tobias Neumann , Susanne Kandolf , Michael Schutzbier , Karl Mechtler , Gijs A Versteeg , David Haselbach , Johannes Zuber

SPOP targets the immune transcription factor IRF1 for proteasomal degradation.

eLife

Avec: Irene Schwartz , Milica Vunjak , Valentina Budroni , Adriana Cantoran García , Marialaura Mastrovito , Adrian Soderholm , Melanie de Almeida , Kathrin Hacker , Jingkui Wang , Kimon Froussios , Julian Jude , Thomas Decker , Johannes Zuber , Gijs A Versteeg

Multilayered VBC score predicts sgRNAs that efficiently generate loss-of-function alleles.

Nature methods

Avec: Georg Michlits , Julian Jude , Melanie de Almeida , Gintautas Vainorius , Maria Hubmann , Tobias Neumann , Alexander Schleiffer , Thomas Rainer Burkard , Michaela Fellner , Max Gijsbertsen , Anna Traunbauer , Johannes Zuber , Ulrich Elling

STAG1 vulnerabilities for exploiting cohesin synthetic lethality in STAG2-deficient cancers.

Life science alliance

Avec: Petra van der Lelij , Joseph A Newman , Simone Lieb , Julian Jude , Vittorio Katis , Thomas Hoffmann , Gerd Bader , Norbert Kraut , Mark A Pearson , Jan-Michael Peters , Johannes Zuber , Opher Gileadi , Mark Petronczki

Targeted protein degradation via intramolecular bivalent glues.

Nature

Avec: Oliver Hsia , Angus D Cowan , Kentaro Iso , Tasuku Ishida , Ramasubramanian Sundaramoorthy , Mark A Nakasone , Hana Imrichova , Caroline Schätz , Andrea Rukavina , Koraljka Husnjak , Martin Wegner , Alejandro Correa-Sáez , Conner Craigon , Ryan Casement , Chiara Maniaci , Andrea Testa , Manuel Kaulich , Ivan Dikic , Georg E Winter , Alessio Ciulli

Functional-genetic approaches to understanding drug response and resistance.

Current opinion in genetics & development

Avec: Johannes Zuber

Inducible knock-out of BCL6 in lymphoma cells results in tumor stasis.

Oncotarget

Avec: Stefanie Schlager , Carina Salomon , Sabine Olt , Christoph Albrecht , Anja Ebert , Oliver Bergner , Johannes Wachter , Francesca Trapani , Daniel Gerlach , Tilman Voss , Anna Traunbauer , Julian Jude , Martina Minnich , Norbert Schweifer , Sophia M Blake , Vittoria Zinzalla , Barbara Drobits , Darryl B McConnell , Norbert Kraut , Mark Pearson , Johannes Zuber , Manfred Koegl

Precision RNAi using synthetic shRNAmir target sites.

eLife

Avec: Thomas Hoffmann , Alexandra Hörmann , Maja Corcokovic , Jakub Zmajkovic , Jasko Salkanovic , Fiona Spreitzer , Anna Köferle , Katrin Gitschtaler , Alexandra Popa , Sarah Oberndorfer , Florian Andersch , Markus Schaefer , Michaela Fellner , Nicole Budano , Jan G Ruppert , Paolo Chetta , Melanie Wurm , Johannes Zuber , Ralph A Neumüller

Réseau de co-auteurs

Johannes Zuber 9 collaborations

Julian Jude 5 collaborations

Georg E Winter 4 collaborations

Hana Imrichova 3 collaborations

Michaela Fellner 3 collaborations

Melanie de Almeida 3 collaborations

Gary Tin 2 collaborations

Marko Cigler 2 collaborations

Steven P Gygi 2 collaborations

Florian Andersch 2 collaborations

Alexander Schleiffer 2 collaborations

Milica Vunjak 2 collaborations

Tobias Neumann 2 collaborations

Gijs A Versteeg 2 collaborations

Anna Traunbauer 2 collaborations

Thomas Hoffmann 2 collaborations

Norbert Kraut 2 collaborations

Kevin D Dong 1 collaboration

Gang Xue 1 collaboration

Jianing Xie 1 collaboration

Lara Dötsch 1 collaboration

Philipp Lampe 1 collaboration

Xiufen Cheng 1 collaboration

Soheila Rezaei Adariani 1 collaboration

Herbert Waldmann 1 collaboration

Chrysanthi Kagiou 1 collaboration

Jose A Cisneros 1 collaboration

Jakob Farnung 1 collaboration

Joanna Liwocha 1 collaboration

Fabian Offensperger 1 collaboration

Kevin Dong 1 collaboration

Ka Yang 1 collaboration

Christina S Horstmann 1 collaboration

Joao A Paulo 1 collaboration

Natalie S Scholes 1 collaboration

Juan Sanchez Avila 1 collaboration

J Thomas Hannich 1 collaboration

Stefan Kubicek 1 collaboration

Brenda A Schulman 1 collaboration

Binbin Wang 1 collaboration

Mei Wang 1 collaboration

Wubing Zhang 1 collaboration

Tengfei Xiao 1 collaboration

Chen-Hao Chen 1 collaboration

Alexander Wu 1 collaboration

Feizhen Wu 1 collaboration

Nicole Traugh 1 collaboration

Xiaoqing Wang 1 collaboration

Ziyi Li 1 collaboration

Shenglin Mei 1 collaboration

Yingbo Cui 1 collaboration

Sailing Shi 1 collaboration

Jesse Jonathan Lipp 1 collaboration

Myles Brown 1 collaboration

Wei Li 1 collaboration

X Shirley Liu 1 collaboration

Hanna Brunner 1 collaboration

Irina Grishkovskaya 1 collaboration

Kashish Singh 1 collaboration

Sumit Deswal 1 collaboration

Robert Kalis 1 collaboration

Thomas Lendl 1 collaboration

Richard Imre 1 collaboration

Elisabeth Roitinger 1 collaboration

Susanne Kandolf 1 collaboration

Michael Schutzbier 1 collaboration

Karl Mechtler 1 collaboration

David Haselbach 1 collaboration

Irene Schwartz 1 collaboration

Valentina Budroni 1 collaboration

Adriana Cantoran García 1 collaboration

Marialaura Mastrovito 1 collaboration

Adrian Soderholm 1 collaboration

Kathrin Hacker 1 collaboration

Jingkui Wang 1 collaboration

Kimon Froussios 1 collaboration

Thomas Decker 1 collaboration

Georg Michlits 1 collaboration

Gintautas Vainorius 1 collaboration

Maria Hubmann 1 collaboration

Thomas Rainer Burkard 1 collaboration

Max Gijsbertsen 1 collaboration

Ulrich Elling 1 collaboration

Petra van der Lelij 1 collaboration

Joseph A Newman 1 collaboration

Simone Lieb 1 collaboration

Vittorio Katis 1 collaboration

Gerd Bader 1 collaboration

Mark A Pearson 1 collaboration

Jan-Michael Peters 1 collaboration

Opher Gileadi 1 collaboration

Mark Petronczki 1 collaboration

Oliver Hsia 1 collaboration

Angus D Cowan 1 collaboration

Kentaro Iso 1 collaboration

Tasuku Ishida 1 collaboration

Ramasubramanian Sundaramoorthy 1 collaboration

Mark A Nakasone 1 collaboration

Caroline Schätz 1 collaboration

Andrea Rukavina 1 collaboration

Koraljka Husnjak 1 collaboration

Martin Wegner 1 collaboration

Alejandro Correa-Sáez 1 collaboration

Conner Craigon 1 collaboration

Ryan Casement 1 collaboration

Chiara Maniaci 1 collaboration

Andrea Testa 1 collaboration

Manuel Kaulich 1 collaboration

Ivan Dikic 1 collaboration

Alessio Ciulli 1 collaboration

Stefanie Schlager 1 collaboration

Carina Salomon 1 collaboration

Sabine Olt 1 collaboration

Christoph Albrecht 1 collaboration

Anja Ebert 1 collaboration

Oliver Bergner 1 collaboration

Johannes Wachter 1 collaboration

Francesca Trapani 1 collaboration

Daniel Gerlach 1 collaboration

Tilman Voss 1 collaboration

Martina Minnich 1 collaboration

Norbert Schweifer 1 collaboration

Sophia M Blake 1 collaboration

Vittoria Zinzalla 1 collaboration

Barbara Drobits 1 collaboration

Darryl B McConnell 1 collaboration

Mark Pearson 1 collaboration

Manfred Koegl 1 collaboration

Alexandra Hörmann 1 collaboration

Maja Corcokovic 1 collaboration

Jakub Zmajkovic 1 collaboration

Jasko Salkanovic 1 collaboration

Fiona Spreitzer 1 collaboration

Anna Köferle 1 collaboration

Katrin Gitschtaler 1 collaboration

Alexandra Popa 1 collaboration

Sarah Oberndorfer 1 collaboration

Markus Schaefer 1 collaboration

Nicole Budano 1 collaboration

Jan G Ruppert 1 collaboration

Paolo Chetta 1 collaboration

Melanie Wurm 1 collaboration

Ralph A Neumüller 1 collaboration