Matthew Lindon

Affiliations

Epigenetics Discovery Performance Unit, GlaxoSmithKline, Medicines Research Centre, Stevenage, Hertfordshire SG1 2NY, U.K.

Publications (5)

Design and Synthesis of a Highly Selective and

Journal of medicinal chemistry

Avec: Alex Preston , Stephen Atkinson , Paul Bamborough , Chun-Wa Chung , Peter D Craggs , Laurie Gordon , Paola Grandi , James R J Gray , Emma J Jones , Anne-Marie Michon , Darren J Mitchell , Rab K Prinjha , Francesco Rianjongdee , Inmaculada Rioja , Jonathan Seal , Simon Taylor , Ian Wall , Robert J Watson , James Woolven , Emmanuel H Demont

Selective targeting of BD1 and BD2 of the BET proteins in cancer and immunoinflammation.

Science (New York, N.Y.)

Avec: Omer Gilan , Inmaculada Rioja , Kathy Knezevic , Matthew J Bell , Miriam M Yeung , Nicola R Harker , Enid Y N Lam , Chun-Wa Chung , Paul Bamborough , Massimo Petretich , Marjeta Urh , Stephen J Atkinson , Anna K Bassil , Emma J Roberts , Dane Vassiliadis , Marian L Burr , Alex G S Preston , Christopher Wellaway , Thilo Werner , James R Gray , Anne-Marie Michon , Thomas Gobbetti , Vinod Kumar , Peter E Soden , Andrea Haynes , Johanna Vappiani , David F Tough , Simon Taylor , Sarah-Jane Dawson , Marcus Bantscheff , Gerard Drewes , Emmanuel H Demont , Danette L Daniels , Paola Grandi , Rab K Prinjha , Mark A Dawson

The Optimization of a Novel, Weak Bromo and Extra Terminal Domain (BET) Bromodomain Fragment Ligand to a Potent and Selective Second Bromodomain (BD2) Inhibitor.

Journal of medicinal chemistry

Avec: Jonathan T Seal , Stephen J Atkinson , Helen Aylott , Paul Bamborough , Chun-Wa Chung , Royston C B Copley , Laurie Gordon , Paola Grandi , James R J Gray , Lee A Harrison , Thomas G Hayhow , Cassie Messenger , Anne-Marie Michon , Darren Mitchell , Alex Preston , Rab K Prinjha , Inmaculada Rioja , Simon Taylor , Ian D Wall , Robert J Watson , James M Woolven , Emmanuel H Demont

Structure-based optimisation of orally active & reversible MetAP-2 inhibitors maintaining a tight 'molecular budget'.

Bioorganic & medicinal chemistry letters

Avec: David J Hirst , Martin Brandt , Gordon Bruton , Erica Christodoulou , Leanne Cutler , Nigel Deeks , Jonathan D Goodacre , Torquil Jack , Afjal Miah , Kevin Page , Nigel Parr , Lena Shukla , Martin Sims , Pamela Thomas , James Thorpe , Duncan S Holmes

Application of Atypical Acetyl-lysine Methyl Mimetics in the Development of Selective Inhibitors of the Bromodomain-Containing Protein 7 (BRD7)/Bromodomain-Containing Protein 9 (BRD9) Bromodomains.

Journal of medicinal chemistry

Avec: Michael A Clegg , Paul Bamborough , Chun-Wa Chung , Peter D Craggs , Laurie Gordon , Paola Grandi , Melanie Leveridge , Gemma M Liwicki , Anne-Marie Michon , Judit Molnar , Inmaculada Rioja , Peter E Soden , Natalie H Theodoulou , Thilo Werner , Nicholas C O Tomkinson , Rab K Prinjha , Philip G Humphreys

Réseau de co-auteurs

Paul Bamborough 4 collaborations

Chun-Wa Chung 4 collaborations

Paola Grandi 4 collaborations

Anne-Marie Michon 4 collaborations

Rab K Prinjha 4 collaborations

Inmaculada Rioja 4 collaborations

Laurie Gordon 3 collaborations

Simon Taylor 3 collaborations

Emmanuel H Demont 3 collaborations

Alex Preston 2 collaborations

Peter D Craggs 2 collaborations

James R J Gray 2 collaborations

Robert J Watson 2 collaborations

Stephen J Atkinson 2 collaborations

Thilo Werner 2 collaborations

Peter E Soden 2 collaborations

Stephen Atkinson 1 collaboration

Emma J Jones 1 collaboration

Darren J Mitchell 1 collaboration

Francesco Rianjongdee 1 collaboration

Jonathan Seal 1 collaboration

Ian Wall 1 collaboration

James Woolven 1 collaboration

Omer Gilan 1 collaboration

Kathy Knezevic 1 collaboration

Matthew J Bell 1 collaboration

Miriam M Yeung 1 collaboration

Nicola R Harker 1 collaboration

Enid Y N Lam 1 collaboration

Massimo Petretich 1 collaboration

Marjeta Urh 1 collaboration

Anna K Bassil 1 collaboration

Emma J Roberts 1 collaboration

Dane Vassiliadis 1 collaboration

Marian L Burr 1 collaboration

Alex G S Preston 1 collaboration

Christopher Wellaway 1 collaboration

James R Gray 1 collaboration

Thomas Gobbetti 1 collaboration

Vinod Kumar 1 collaboration

Andrea Haynes 1 collaboration

Johanna Vappiani 1 collaboration

David F Tough 1 collaboration

Sarah-Jane Dawson 1 collaboration

Marcus Bantscheff 1 collaboration

Gerard Drewes 1 collaboration

Danette L Daniels 1 collaboration

Mark A Dawson 1 collaboration

Jonathan T Seal 1 collaboration

Helen Aylott 1 collaboration

Royston C B Copley 1 collaboration

Lee A Harrison 1 collaboration

Thomas G Hayhow 1 collaboration

Cassie Messenger 1 collaboration

Darren Mitchell 1 collaboration

Ian D Wall 1 collaboration

James M Woolven 1 collaboration

David J Hirst 1 collaboration

Martin Brandt 1 collaboration

Gordon Bruton 1 collaboration

Erica Christodoulou 1 collaboration

Leanne Cutler 1 collaboration

Nigel Deeks 1 collaboration

Jonathan D Goodacre 1 collaboration

Torquil Jack 1 collaboration

Afjal Miah 1 collaboration

Kevin Page 1 collaboration

Nigel Parr 1 collaboration

Lena Shukla 1 collaboration

Martin Sims 1 collaboration

Pamela Thomas 1 collaboration

James Thorpe 1 collaboration

Duncan S Holmes 1 collaboration

Michael A Clegg 1 collaboration

Melanie Leveridge 1 collaboration

Gemma M Liwicki 1 collaboration

Judit Molnar 1 collaboration

Natalie H Theodoulou 1 collaboration

Nicholas C O Tomkinson 1 collaboration

Philip G Humphreys 1 collaboration