Martina Molgora

Affiliations

Department of Pathology and Immunology, Washington University School of Medicine, St Louis, MO, 63110, USA.

Publications (21)

Turning enemies into allies-reprogramming tumor-associated macrophages for cancer therapy.

Med (New York, N.Y.)

Avec: Marco Colonna

TREM2 Modulation Remodels the Tumor Myeloid Landscape Enhancing Anti-PD-1 Immunotherapy.

Cell

Avec: Ekaterina Esaulova , William Vermi , Jinchao Hou , Yun Chen , Jingqin Luo , Simone Brioschi , Mattia Bugatti , Andrea Salvatore Omodei , Biancamaria Ricci , Catrina Fronick , Santosh K Panda , Yoshiko Takeuchi , Matthew M Gubin , Roberta Faccio , Marina Cella , Susan Gilfillan , Emil R Unanue , Maxim N Artyomov , Robert D Schreiber , Marco Colonna

TREM2 deficiency reprograms intestinal macrophages and microbiota to enhance anti-PD-1 tumor immunotherapy.

Science immunology

Avec: Blanda Di Luccia , Darya Khantakova , Natalia Jaeger , Hao-Wei Chang , Rafael S Czepielewski , Beth A Helmink , Emily J Onufer , José L Fachi , Bishan Bhattarai , Tihana Trsan , Patrick F Rodrigues , JinChao Hou , Jennifer K Bando , Cristiane Sécca da Silva , Marina Cella , Susan Gilfillan , Robert D Schreiber , Jeffrey I Gordon , Marco Colonna

TREM2 macrophages drive NK cell paucity and dysfunction in lung cancer.

Nature immunology

Avec: Matthew D Park , Ivan Reyes-Torres , Jessica LeBerichel , Pauline Hamon , Nelson M LaMarche , Samarth Hegde , Meriem Belabed , Leanna Troncoso , John A Grout , Assaf Magen , Etienne Humblin , Achuth Nair , Jinchao Hou , Jenna H Newman , Adam M Farkas , Andrew M Leader , Travis Dawson , Darwin D'Souza , Steven Hamel , Alfonso Rodriguez Sanchez-Paulete , Barbara Maier , Nina Bhardwaj , Jerome C Martin , Alice O Kamphorst , Ephraim Kenigsberg , Maria Casanova-Acebes , Amir Horowitz , Brian D Brown , Lucas Ferrari De Andrade , Marco Colonna , Thomas U Marron , Miriam Merad

TREM2: A new player in the tumor microenvironment.

Seminars in immunology

Avec: Yizhou A Liu , Marco Colonna , Marina Cella

The macrophage tetraspan MS4A4A enhances dectin-1-dependent NK cell-mediated resistance to metastasis.

Nature immunology

Avec: Irene Mattiola , Federica Tomay , Maria De Pizzol , Rita Silva-Gomes , Benedetta Savino , Tamara Gulic , Andrea Doni , Silvia Lonardi , Marie Astrid Boutet , Alessandra Nerviani , Roberta Carriero , Matteo Stravalaci , Diego Morone , Irina N Shalova , Yunquin Lee , Subhra K Biswas , Giovanna Mantovani , Marina Sironi , Costantino Pitzalis , William Vermi , Barbara Bottazzi , Alberto Mantovani , Massimo Locati

Single-Cell Sequencing of Mouse Heart Immune Infiltrate in Pressure Overload-Driven Heart Failure Reveals Extent of Immune Activation.

Circulation

Avec: Elisa Martini , Paolo Kunderfranco , Clelia Peano , Pierluigi Carullo , Marco Cremonesi , Tilo Schorn , Roberta Carriero , Alberto Termanini , Federico Simone Colombo , Elena Jachetti , Cristina Panico , Giuseppe Faggian , Andrea Fumero , Lucia Torracca , Javier Cibella , Christina Pagiatakis , Jolanda Brummelman , Giorgia Alvisi , Emilia Maria Cristina Mazza , Mario Paolo Colombo , Enrico Lugli , Gianluigi Condorelli , Marinos Kallikourdis

Comparing neoantigen cancer vaccines and immune checkpoint therapy unveils an effective vaccine and anti-TREM2 macrophage-targeting dual therapy.

Cell reports

Avec: Sunita Keshari , Alexander S Shavkunov , Qi Miao , Akata Saha , Tomoyuki Minowa , Charmelle D Williams , Mehdi Chaib , Anna M Highsmith , Josué E Pineda , Sayan Alekseev , Elise Alspach , Kenneth H Hu , Marco Colonna , Kristen E Pauken , Ken Chen , Matthew M Gubin

Pentraxin 3 deficiency protects from the metabolic inflammation associated to diet-induced obesity.

Cardiovascular research

Avec: Fabrizia Bonacina , Annalisa Moregola , Rémi Porte , Andrea Baragetti , Eduardo Bonavita , Alice Salatin , Liliana Grigore , Fabio Pellegatta , Marina Sironi , Elisa Barbati , Alberto Mantovani , Barbara Bottazzi , Alberico Luigi Catapano , Cecilia Garlanda , Giuseppe Danilo Norata

Interleukin-1 and Related Cytokines in the Regulation of Inflammation and Immunity.

Immunity

Avec: Alberto Mantovani , Charles A Dinarello , Cecilia Garlanda

Weight Bias Internalization and Eating Disorder Psychopathology in Treatment-Seeking Patients with Obesity.

Nutrients

Avec: Simona Calugi , Barbara Segattini , Gianmatteo Cattaneo , Mirko Chimini , Anna Dalle Grave , Laura Dametti , Manuela Molgora , Riccardo Dalle Grave

Amplification of autoimmune organ damage by NKp46-activated ILC1.

Nature

Avec: Stylianos-Iason Biniaris-Georgallis , Tom Aschman , Katerina Stergioula , Frauke Schreiber , Vajiheh Jafari , Anna Taranko , Tejal Karmalkar , Ana Kasapi , Tihana Lenac Rovis , Vedrana Jelencic , David A Bejarano , Lea Fabry , Michail Papacharalampous , Irene Mattiola , Jinchao Hou , Karolin W Hublitz , Frederik Heinrich , Gabriela Maria Guerra , Pawel Durek , Giannino Patone , Eric Lars-Helge Lindberg , Henrike Maatz , Oliver Hölsken , Gerhard Krönke , Arthur Mortha , Reinhard E Voll , Alexander J Clarke , Anja E Hauser , Marco Colonna , Kevin Thurley , Andreas Schlitzer , Christoph Schneider , Efstathios G Stamatiades , Mir-Farzin Mashreghi , Stipan Jonjic , Norbert Hübner , Andreas Diefenbach , Masatoshi Kanda , Antigoni Triantafyllopoulou

At the interface of tumor-associated macrophages and fibroblasts: immune-suppressive networks and emerging exploitable targets.

Clinical cancer research : an official journal of the American Association for Cancer Research

Avec: Eleonora Timperi , Hugo Croizer , Darya Khantakova , Mhaidly Rana , Jennifer L Guerriero , Fatima Mechta-Grigoriou , Emanuela Romano

Neutrophils Driving Unconventional T Cells Mediate Resistance against Murine Sarcomas and Selected Human Tumors.

Cell

Avec: Andrea Ponzetta , Roberta Carriero , Silvia Carnevale , Marialuisa Barbagallo , Chiara Perucchini , Elena Magrini , Francesca Gianni , Paolo Kunderfranco , Nadia Polentarutti , Fabio Pasqualini , Sabrina Di Marco , Domenico Supino , Clelia Peano , Ferdinando Cananzi , Piergiuseppe Colombo , Silvana Pilotti , Suliman Yousef Alomar , Eduardo Bonavita , Maria Rosaria Galdiero , Cecilia Garlanda , Alberto Mantovani , Sebastien Jaillon

The Fibronectin-ILT3 Interaction Functions as a Stromal Checkpoint that Suppresses Myeloid Cells.

Cancer immunology research

Avec: Kevin J Paavola , Julie M Roda , Vicky Y Lin , Peirong Chen , Kyle P O'Hollaren , Richard Ventura , Suzanne C Crawley , Betty Li , Hung-I H Chen , Seth Malmersjö , Nikolai A Sharkov , Geoffrey Horner , Wei Guo , Alan K Kutach , Kalyani Mondal , Zhen Zhang , Joshua S Lichtman , Christina Song , Lee B Rivera , Wenhui Liu , Jian Luo , Yan Wang , Mark J Solloway , Bernard B Allan , Avantika Kekatpure , Shelley R Starck , Raj Haldankar , Bin Fan , Chun Chu , Jie Tang , Marco Colonna , Daniel D Kaplan , Jer-Yuan Hsu

Killing the Invaders: NK Cell Impact in Tumors and Anti-Tumor Therapy.

Cancers

Avec: Victor S Cortez , Marco Colonna

Inositol phosphatase INPP4B sustains ILC1s and intratumoral NK cells through an AKT-driven pathway.

The Journal of experimental medicine

Avec: Vincent Peng , Tihana Trsan , Raki Sudan , Bishan Bhattarai , Victor S Cortez , Jean Vacher , Marco Colonna

Lipid-Associated Macrophages Are Induced by Cancer-Associated Fibroblasts and Mediate Immune Suppression in Breast Cancer.

Cancer research

Avec: Eleonora Timperi , Paul Gueguen , Ilaria Magagna , Yann Kieffer , Silvia Lopez-Lastra , Philemon Sirven , Laura G Baudrin , Sylvain Baulande , André Nicolas , Gabriel Champenois , Didier Meseure , Anne Vincent-Salomon , Anne Tardivon , Enora Laas , Vassili Soumelis , Marco Colonna , Fatima Mechta-Grigoriou , Sebastian Amigorena , Emanuela Romano

Innate-like T cells: A promising asset in anti-cancer immunity.

Cancer cell

Avec: Marco Colonna

Exploring the Impact of TREM2 in Tumor-Associated Macrophages.

Vaccines

Avec: Darya Khantakova , Simone Brioschi ,

A Cre-deleter specific for embryo-derived brain macrophages reveals distinct features of microglia and border macrophages.

Immunity

Avec: Simone Brioschi , Julia A Belk , Vincent Peng , Patrick Fernandes Rodrigues , Khai M Nguyen , Shoutang Wang , Siling Du , Wei-Le Wang , Gary E Grajales-Reyes , Jennifer M Ponce , Carla M Yuede , Qingyun Li , John M Baer , David G DeNardo , Susan Gilfillan , Marina Cella , Ansuman T Satpathy , Marco Colonna

Réseau de co-auteurs

Marco Colonna 13 collaborations

Marina Cella 4 collaborations

Alberto Mantovani 4 collaborations

Jinchao Hou 3 collaborations

Simone Brioschi 3 collaborations

Susan Gilfillan 3 collaborations

Darya Khantakova 3 collaborations

Roberta Carriero 3 collaborations

Cecilia Garlanda 3 collaborations

William Vermi 2 collaborations

Matthew M Gubin 2 collaborations

Robert D Schreiber 2 collaborations

Bishan Bhattarai 2 collaborations

Tihana Trsan 2 collaborations

Irene Mattiola 2 collaborations

Marina Sironi 2 collaborations

Barbara Bottazzi 2 collaborations

Paolo Kunderfranco 2 collaborations

Clelia Peano 2 collaborations

Eduardo Bonavita 2 collaborations

Eleonora Timperi 2 collaborations

Fatima Mechta-Grigoriou 2 collaborations

Emanuela Romano 2 collaborations

Victor S Cortez 2 collaborations

Vincent Peng 2 collaborations

Ekaterina Esaulova 1 collaboration

Yun Chen 1 collaboration

Jingqin Luo 1 collaboration

Mattia Bugatti 1 collaboration

Andrea Salvatore Omodei 1 collaboration

Biancamaria Ricci 1 collaboration

Catrina Fronick 1 collaboration

Santosh K Panda 1 collaboration

Yoshiko Takeuchi 1 collaboration

Roberta Faccio 1 collaboration

Emil R Unanue 1 collaboration

Maxim N Artyomov 1 collaboration

Blanda Di Luccia 1 collaboration

Natalia Jaeger 1 collaboration

Hao-Wei Chang 1 collaboration

Rafael S Czepielewski 1 collaboration

Beth A Helmink 1 collaboration

Emily J Onufer 1 collaboration

José L Fachi 1 collaboration

Patrick F Rodrigues 1 collaboration

JinChao Hou 1 collaboration

Jennifer K Bando 1 collaboration

Cristiane Sécca da Silva 1 collaboration

Jeffrey I Gordon 1 collaboration

Matthew D Park 1 collaboration

Ivan Reyes-Torres 1 collaboration

Jessica LeBerichel 1 collaboration

Pauline Hamon 1 collaboration

Nelson M LaMarche 1 collaboration

Samarth Hegde 1 collaboration

Meriem Belabed 1 collaboration

Leanna Troncoso 1 collaboration

John A Grout 1 collaboration

Assaf Magen 1 collaboration

Etienne Humblin 1 collaboration

Achuth Nair 1 collaboration

Jenna H Newman 1 collaboration

Adam M Farkas 1 collaboration

Andrew M Leader 1 collaboration

Travis Dawson 1 collaboration

Darwin D'Souza 1 collaboration

Steven Hamel 1 collaboration

Alfonso Rodriguez Sanchez-Paulete 1 collaboration

Barbara Maier 1 collaboration

Nina Bhardwaj 1 collaboration

Jerome C Martin 1 collaboration

Alice O Kamphorst 1 collaboration

Ephraim Kenigsberg 1 collaboration

Maria Casanova-Acebes 1 collaboration

Amir Horowitz 1 collaboration

Brian D Brown 1 collaboration

Lucas Ferrari De Andrade 1 collaboration

Thomas U Marron 1 collaboration

Miriam Merad 1 collaboration

Yizhou A Liu 1 collaboration

Federica Tomay 1 collaboration

Maria De Pizzol 1 collaboration

Rita Silva-Gomes 1 collaboration

Benedetta Savino 1 collaboration

Tamara Gulic 1 collaboration

Andrea Doni 1 collaboration

Silvia Lonardi 1 collaboration

Marie Astrid Boutet 1 collaboration

Alessandra Nerviani 1 collaboration

Matteo Stravalaci 1 collaboration

Diego Morone 1 collaboration

Irina N Shalova 1 collaboration

Yunquin Lee 1 collaboration

Subhra K Biswas 1 collaboration

Giovanna Mantovani 1 collaboration

Costantino Pitzalis 1 collaboration

Massimo Locati 1 collaboration

Elisa Martini 1 collaboration

Pierluigi Carullo 1 collaboration

Marco Cremonesi 1 collaboration

Tilo Schorn 1 collaboration

Alberto Termanini 1 collaboration

Federico Simone Colombo 1 collaboration

Elena Jachetti 1 collaboration

Cristina Panico 1 collaboration

Giuseppe Faggian 1 collaboration

Andrea Fumero 1 collaboration

Lucia Torracca 1 collaboration

Javier Cibella 1 collaboration

Christina Pagiatakis 1 collaboration

Jolanda Brummelman 1 collaboration

Giorgia Alvisi 1 collaboration

Emilia Maria Cristina Mazza 1 collaboration

Mario Paolo Colombo 1 collaboration

Enrico Lugli 1 collaboration

Gianluigi Condorelli 1 collaboration

Marinos Kallikourdis 1 collaboration

Sunita Keshari 1 collaboration

Alexander S Shavkunov 1 collaboration

Qi Miao 1 collaboration

Akata Saha 1 collaboration

Tomoyuki Minowa 1 collaboration

Charmelle D Williams 1 collaboration

Mehdi Chaib 1 collaboration

Anna M Highsmith 1 collaboration

Josué E Pineda 1 collaboration

Sayan Alekseev 1 collaboration

Elise Alspach 1 collaboration

Kenneth H Hu 1 collaboration

Kristen E Pauken 1 collaboration

Ken Chen 1 collaboration

Fabrizia Bonacina 1 collaboration

Annalisa Moregola 1 collaboration

Rémi Porte 1 collaboration

Andrea Baragetti 1 collaboration

Alice Salatin 1 collaboration

Liliana Grigore 1 collaboration

Fabio Pellegatta 1 collaboration

Elisa Barbati 1 collaboration

Alberico Luigi Catapano 1 collaboration

Giuseppe Danilo Norata 1 collaboration

Charles A Dinarello 1 collaboration

Simona Calugi 1 collaboration

Barbara Segattini 1 collaboration

Gianmatteo Cattaneo 1 collaboration

Mirko Chimini 1 collaboration

Anna Dalle Grave 1 collaboration

Laura Dametti 1 collaboration

Manuela Molgora 1 collaboration

Riccardo Dalle Grave 1 collaboration

Stylianos-Iason Biniaris-Georgallis 1 collaboration

Tom Aschman 1 collaboration

Katerina Stergioula 1 collaboration

Frauke Schreiber 1 collaboration

Vajiheh Jafari 1 collaboration

Anna Taranko 1 collaboration

Tejal Karmalkar 1 collaboration

Ana Kasapi 1 collaboration

Tihana Lenac Rovis 1 collaboration

Vedrana Jelencic 1 collaboration

David A Bejarano 1 collaboration

Lea Fabry 1 collaboration

Michail Papacharalampous 1 collaboration

Karolin W Hublitz 1 collaboration

Frederik Heinrich 1 collaboration

Gabriela Maria Guerra 1 collaboration

Pawel Durek 1 collaboration

Giannino Patone 1 collaboration

Eric Lars-Helge Lindberg 1 collaboration

Henrike Maatz 1 collaboration

Oliver Hölsken 1 collaboration

Gerhard Krönke 1 collaboration

Arthur Mortha 1 collaboration

Reinhard E Voll 1 collaboration

Alexander J Clarke 1 collaboration

Anja E Hauser 1 collaboration

Kevin Thurley 1 collaboration

Andreas Schlitzer 1 collaboration

Christoph Schneider 1 collaboration

Efstathios G Stamatiades 1 collaboration

Mir-Farzin Mashreghi 1 collaboration

Stipan Jonjic 1 collaboration

Norbert Hübner 1 collaboration

Andreas Diefenbach 1 collaboration

Masatoshi Kanda 1 collaboration

Antigoni Triantafyllopoulou 1 collaboration

Hugo Croizer 1 collaboration

Mhaidly Rana 1 collaboration

Jennifer L Guerriero 1 collaboration

Andrea Ponzetta 1 collaboration

Silvia Carnevale 1 collaboration

Marialuisa Barbagallo 1 collaboration

Chiara Perucchini 1 collaboration

Elena Magrini 1 collaboration

Francesca Gianni 1 collaboration

Nadia Polentarutti 1 collaboration

Fabio Pasqualini 1 collaboration

Sabrina Di Marco 1 collaboration

Domenico Supino 1 collaboration

Ferdinando Cananzi 1 collaboration

Piergiuseppe Colombo 1 collaboration

Silvana Pilotti 1 collaboration

Suliman Yousef Alomar 1 collaboration

Maria Rosaria Galdiero 1 collaboration

Sebastien Jaillon 1 collaboration

Kevin J Paavola 1 collaboration

Julie M Roda 1 collaboration

Vicky Y Lin 1 collaboration

Peirong Chen 1 collaboration

Kyle P O'Hollaren 1 collaboration

Richard Ventura 1 collaboration

Suzanne C Crawley 1 collaboration

Betty Li 1 collaboration

Hung-I H Chen 1 collaboration

Seth Malmersjö 1 collaboration

Nikolai A Sharkov 1 collaboration

Geoffrey Horner 1 collaboration

Wei Guo 1 collaboration

Alan K Kutach 1 collaboration

Kalyani Mondal 1 collaboration

Zhen Zhang 1 collaboration

Joshua S Lichtman 1 collaboration

Christina Song 1 collaboration

Lee B Rivera 1 collaboration

Wenhui Liu 1 collaboration

Jian Luo 1 collaboration

Yan Wang 1 collaboration

Mark J Solloway 1 collaboration

Bernard B Allan 1 collaboration

Avantika Kekatpure 1 collaboration

Shelley R Starck 1 collaboration

Raj Haldankar 1 collaboration

Bin Fan 1 collaboration

Chun Chu 1 collaboration

Jie Tang 1 collaboration

Daniel D Kaplan 1 collaboration

Jer-Yuan Hsu 1 collaboration

Raki Sudan 1 collaboration

Jean Vacher 1 collaboration

Paul Gueguen 1 collaboration

Ilaria Magagna 1 collaboration

Yann Kieffer 1 collaboration

Silvia Lopez-Lastra 1 collaboration

Philemon Sirven 1 collaboration

Laura G Baudrin 1 collaboration

Sylvain Baulande 1 collaboration

André Nicolas 1 collaboration

Gabriel Champenois 1 collaboration

Didier Meseure 1 collaboration

Anne Vincent-Salomon 1 collaboration

Anne Tardivon 1 collaboration

Enora Laas 1 collaboration

Vassili Soumelis 1 collaboration

Sebastian Amigorena 1 collaboration

Julia A Belk 1 collaboration

Patrick Fernandes Rodrigues 1 collaboration

Khai M Nguyen 1 collaboration

Shoutang Wang 1 collaboration

Siling Du 1 collaboration

Wei-Le Wang 1 collaboration

Gary E Grajales-Reyes 1 collaboration

Jennifer M Ponce 1 collaboration

Carla M Yuede 1 collaboration

Qingyun Li 1 collaboration

John M Baer 1 collaboration

David G DeNardo 1 collaboration

Ansuman T Satpathy 1 collaboration