Marieke Erica Ijsselsteijn

Affiliations

Department of Pathology, Leiden University Medical Center, 2333ZA, Leiden, The Netherlands.

Publications (23)

Neoantigen-specific immunity in low mutation burden colorectal cancers of the consensus molecular subtype 4.

Genome medicine

Avec: Jitske van den Bulk , Els M E Verdegaal , Dina Ruano , Marieke E Ijsselsteijn , Marten Visser , Ruud van der Breggen , Thomas Duhen , Manon van der Ploeg , Natasja L de Vries , Jan Oosting , Koen C M J Peeters , Andrew D Weinberg , Arantza Farina-Sarasqueta , Sjoerd H van der Burg , Noel F C C de Miranda

Discordant prognosis of mismatch repair deficiency in colorectal and endometrial cancer reflects variation in antitumour immune response and immune escape.

The Journal of pathology

Avec: Mark A Glaire , Neil Aj Ryan , Marieke E Ijsselsteijn , Katarzyna Kedzierska , Sofia Obolenski , Reem Ali , Emma J Crosbie , Tjalling Bosse , Noel Fcc de Miranda , David N Church

VISTA Expression on Cancer-Associated Endothelium Selectively Prevents T-cell Extravasation.

Cancer immunology research

Avec: Sietse J Luk , Rouven Schoppmeyer , Marieke E Ijsselsteijn , Antonios Somarakis , Ibtissam Acem , Dennis F G Remst , Daan T Cox , Cornelis A M van Bergen , Inge Briaire-de Bruijn , Max L B Grönloh , Werner J van der Meer , Lukas J A C Hawinkels , Roman I Koning , Erik Bos , Judith V M G Bovée , Noel F C C de Miranda , Karoly Szuhai , Jaap D van Buul , J H Frederik Falkenburg , Mirjam H M Heemskerk

Transcriptomic and immunophenotypic profiling reveals molecular and immunological hallmarks of colorectal cancer tumourigenesis.

Gut

Avec: Jessica Roelands , Manon van der Ploeg , Marieke E Ijsselsteijn , Hao Dang , Jurjen J Boonstra , James C H Hardwick , Lukas J A C Hawinkels , Hans Morreau , Noel F C C de Miranda

Revisiting immune escape in colorectal cancer in the era of immunotherapy.

British journal of cancer

Avec: Florent Petitprez , Laetitia Lacroix , Dina Ruano , Ruud van der Breggen , Catherine Julie , Hans Morreau , Catherine Sautès-Fridman , Wolf Herman Fridman , Noel Filipe da Cunha Carvalho de Miranda

γδ T cells are effectors of immunotherapy in cancers with HLA class I defects.

Nature

Avec: Natasja L de Vries , Joris van de Haar , Vivien Veninga , Myriam Chalabi , Marieke E Ijsselsteijn , Manon van der Ploeg , Jitske van den Bulk , Dina Ruano , Jose G van den Berg , John B Haanen , Laurien J Zeverijn , Birgit S Geurts , Gijs F de Wit , Thomas W Battaglia , Hans Gelderblom , Henk M W Verheul , Ton N Schumacher , Lodewyk F A Wessels , Frits Koning , Noel F C C de Miranda , Emile E Voest

CD103 and CD39 coexpression identifies neoantigen-specific cytotoxic T cells in colorectal cancers with low mutation burden.

Journal for immunotherapy of cancer

Avec: Jitske van den Bulk , Manon van der Ploeg , Marieke E Ijsselsteijn , Dina Ruano , Ruud van der Breggen , Rebekka Duhen , Koen C M J Peeters , Arantza Fariña-Sarasqueta , Els M E Verdegaal , Sjoerd H van der Burg , Thomas Duhen , Noel F C C de Miranda

Multimodal profiling of chordoma immunity reveals distinct immune contextures.

Journal for immunotherapy of cancer

Avec: Siddh van Oost , Debora M Meijer , Marieke E Ijsselsteijn , Jessica P Roelands , Brendy E M W van den Akker , Ruud van der Breggen , Inge H Briaire-de Bruijn , Manon van der Ploeg , Pauline M Wijers-Koster , Samuel B Polak , Wilco C Peul , Robert J P van der Wal , Noel F C C de Miranda , Judith V M G Bovee

Identification of a unique intervillous cellular signature in chronic histiocytic intervillositis.

Placenta

Avec: Juliette Krop , Lotte E van der Meeren , Marie-Louise P van der Hoorn , Marieke E Ijsselsteijn , Kyra L Dijkstra , H Kapsenberg , C van der Keur , Emily F Cornish , Peter G J Nikkels , Frits Koning , Frans H J Claas , Sebastiaan Heidt , Michael Eikmans , Manon Bos

Location matters: spatial dynamics of tumor-infiltrating T cell subsets is prognostic in colon cancer.

Frontiers in immunology

Avec: Hehuan Zhu , Jessica Roelands , Eiman I Ahmed , Imke Stouten , Rachel Hoorntje , Ronald L P van Vlierberghe , Marieke E Ijsselsteijn , Xin Lei , Noel F C C de Miranda , Rob A E M Tollenaar , Alexander L Vahrmeijer , Davide Bedognetti , Wouter R L Hendrickx , Peter J K Kuppen

Integration of mass cytometry and mass spectrometry imaging for spatially resolved single-cell metabolic profiling.

Nature methods

Avec: Joana B Nunes , Marieke E Ijsselsteijn , Tamim Abdelaal , Rick Ursem , Manon van der Ploeg , Martin Giera , Bart Everts , Ahmed Mahfouz , Bram Heijs , Noel F C C de Miranda

Visual cohort comparison for spatial single-cell omics-data.

IEEE transactions on visualization and computer graphics

Avec: Antonios Somarakis , Marieke E Ijsselsteijn , Sietse J Luk , Boyd Kenkhuis , Noel F C C de Miranda , Boudewijn P F Lelieveldt , Thomas Hollt

Immunophenotype of Gastric Tumors Unveils a Pleiotropic Role of Regulatory T Cells in Tumor Development.

Cancers

Avec: Sara Rocha , Afonso P Basto , Marieke E Ijsselsteijn , Sara P Teles , Maria M Azevedo , Gilza Gonçalves , Irene Gullo , Gabriela M Almeida , Joaquín J Maqueda , Marta I Oliveira , Fátima Carneiro , João T Barata , Luís Graça , Noel F C C de Miranda , Joana Carvalho , Carla Oliveira

Cancer immunophenotyping by seven-colour multispectral imaging without tyramide signal amplification.

The journal of pathology. Clinical research

Avec: Marieke E Ijsselsteijn , Thomas P Brouwer , Ziena Abdulrahman , Eileen Reidy , Ana Ramalheiro , A Marijne Heeren , Alexander Vahrmeijer , Ekaterina S Jordanova , Noel Fcc de Miranda

A 34-Marker Panel for Imaging Mass Cytometric Analysis of Human Snap-Frozen Tissue.

Frontiers in immunology

Avec: Nannan Guo , Vincent van Unen , Marieke E Ijsselsteijn , Laura F Ouboter , Andrea E van der Meulen , Susana M Chuva de Sousa Lopes , Noel F C C de Miranda , Frits Koning , Na Li

Semi-automated background removal limits data loss and normalizes imaging mass cytometry data.

Cytometry. Part A : the journal of the International Society for Analytical Cytology

Avec: Marieke E Ijsselsteijn , Antonios Somarakis , Boudewijn P F Lelieveldt , Thomas Höllt , Noel F C C de Miranda

Imaging mass cytometry reveals the prominent role of myeloid cells at the maternal-fetal interface.

iScience

Avec: Juliette Krop , Anita van der Zwan , Marieke E Ijsselsteijn , Hanneke Kapsenberg , Sietse J Luk , Sanne H Hendriks , Carin van der Keur , Lotte J Verleng , Antonis Somarakis , Lotte van der Meeren , Geert Haasnoot , Manon Bos , Noel F C C de Miranda , Susana M Chuva de Sousa Lopes , Marie-Louise P van der Hoorn , Frits Koning , Frans H J Claas , Sebastiaan Heidt , Michael Eikmans

Neoantigen Targetability in Progressive Advanced Melanoma.

Clinical cancer research : an official journal of the American Association for Cancer Research

Avec: Jitske van den Bulk , Els M E Verdegaal , Manon van der Ploeg , Marten Visser , Joana B Nunes , Arnoud H de Ru , Rayman T N Tjokrodirijo , Marieke E Ijsselsteijn , Natasja I Janssen , Ruud van der Breggen , Linda de Bruin , Pita de Kok , George M C Janssen , Dina Ruano , Ellen H W Kapiteijn , Peter A van Veelen , Noel F C C de Miranda , Sjoerd H van der Burg

A 40-Marker Panel for High Dimensional Characterization of Cancer Immune Microenvironments by Imaging Mass Cytometry.

Frontiers in immunology

Avec: Marieke E Ijsselsteijn , Ruud van der Breggen , Arantza Farina Sarasqueta , Frits Koning , Noel F C C de Miranda

High-dimensional cytometric analysis of colorectal cancer reveals novel mediators of antitumour immunity.

Gut

Avec: Natasja L de Vries , Vincent van Unen , Marieke E Ijsselsteijn , Tamim Abdelaal , Ruud van der Breggen , Arantza Farina Sarasqueta , Ahmed Mahfouz , Koen C M J Peeters , Thomas Höllt , Boudewijn P F Lelieveldt , Frits Koning , Noel F C C de Miranda

Tumor-specific T cells support chemokine-driven spatial organization of intratumoral immune microaggregates needed for long survival.

Journal for immunotherapy of cancer

Avec: Ziena Abdulrahman , Saskia J Santegoets , Gregor Sturm , Pornpimol Charoentong , Marieke E Ijsselsteijn , Antonios Somarakis , Thomas Höllt , Francesca Finotello , Zlatko Trajanoski , Sylvia L van Egmond , Dana A M Mustafa , Marij J P Welters , Noel F C C de Miranda , Sjoerd H van der Burg

The C-type lectin DCIR contributes to the immune response and pathogenesis of colorectal cancer.

Scientific reports

Avec: Giulia Trimaglio , Tamara Sneperger , Benjamin B A Raymond , Nelly Gilles , Emmanuelle Näser , Marie Locard-Paulet , Marieke E Ijsselsteijn , Thomas P Brouwer , Romain Ecalard , Jessica Roelands , Naoki Matsumoto , André Colom , Myriam Habch , Noel F C C de Miranda , Nathalie Vergnolle , Christel Devaud , Olivier Neyrolles , Yoann Rombouts

An imaging mass cytometry immunophenotyping panel for non-human primate tissues.

Frontiers in immunology

Avec: Paula Niewold , Marieke E Ijsselsteijn , Frank A W Verreck , Tom H M Ottenhoff , Simone A Joosten

Réseau de co-auteurs

Marieke E Ijsselsteijn 22 collaborations

Noel F C C de Miranda 18 collaborations

Ruud van der Breggen 7 collaborations

Manon van der Ploeg 7 collaborations

Frits Koning 6 collaborations

Dina Ruano 5 collaborations

Jitske van den Bulk 4 collaborations

Sjoerd H van der Burg 4 collaborations

Antonios Somarakis 4 collaborations

Els M E Verdegaal 3 collaborations

Natasja L de Vries 3 collaborations

Koen C M J Peeters 3 collaborations

Sietse J Luk 3 collaborations

Jessica Roelands 3 collaborations

Boudewijn P F Lelieveldt 3 collaborations

Thomas Höllt 3 collaborations

Marten Visser 2 collaborations

Thomas Duhen 2 collaborations

Noel Fcc de Miranda 2 collaborations

Lukas J A C Hawinkels 2 collaborations

Hans Morreau 2 collaborations

Juliette Krop 2 collaborations

Marie-Louise P van der Hoorn 2 collaborations

Frans H J Claas 2 collaborations

Sebastiaan Heidt 2 collaborations

Michael Eikmans 2 collaborations

Manon Bos 2 collaborations

Joana B Nunes 2 collaborations

Tamim Abdelaal 2 collaborations

Ahmed Mahfouz 2 collaborations

Thomas P Brouwer 2 collaborations

Ziena Abdulrahman 2 collaborations

Vincent van Unen 2 collaborations

Susana M Chuva de Sousa Lopes 2 collaborations

Arantza Farina Sarasqueta 2 collaborations

Jan Oosting 1 collaboration

Andrew D Weinberg 1 collaboration

Arantza Farina-Sarasqueta 1 collaboration

Mark A Glaire 1 collaboration

Neil Aj Ryan 1 collaboration

Katarzyna Kedzierska 1 collaboration

Sofia Obolenski 1 collaboration

Reem Ali 1 collaboration

Emma J Crosbie 1 collaboration

Tjalling Bosse 1 collaboration

David N Church 1 collaboration

Rouven Schoppmeyer 1 collaboration

Ibtissam Acem 1 collaboration

Dennis F G Remst 1 collaboration

Daan T Cox 1 collaboration

Cornelis A M van Bergen 1 collaboration

Inge Briaire-de Bruijn 1 collaboration

Max L B Grönloh 1 collaboration

Werner J van der Meer 1 collaboration

Roman I Koning 1 collaboration

Erik Bos 1 collaboration

Judith V M G Bovée 1 collaboration

Karoly Szuhai 1 collaboration

Jaap D van Buul 1 collaboration

J H Frederik Falkenburg 1 collaboration

Mirjam H M Heemskerk 1 collaboration

Hao Dang 1 collaboration

Jurjen J Boonstra 1 collaboration

James C H Hardwick 1 collaboration

Florent Petitprez 1 collaboration

Laetitia Lacroix 1 collaboration

Catherine Julie 1 collaboration

Catherine Sautès-Fridman 1 collaboration

Wolf Herman Fridman 1 collaboration

Noel Filipe da Cunha Carvalho de Miranda 1 collaboration

Joris van de Haar 1 collaboration

Vivien Veninga 1 collaboration

Myriam Chalabi 1 collaboration

Jose G van den Berg 1 collaboration

John B Haanen 1 collaboration

Laurien J Zeverijn 1 collaboration

Birgit S Geurts 1 collaboration

Gijs F de Wit 1 collaboration

Thomas W Battaglia 1 collaboration

Hans Gelderblom 1 collaboration

Henk M W Verheul 1 collaboration

Ton N Schumacher 1 collaboration

Lodewyk F A Wessels 1 collaboration

Emile E Voest 1 collaboration

Rebekka Duhen 1 collaboration

Arantza Fariña-Sarasqueta 1 collaboration

Siddh van Oost 1 collaboration

Debora M Meijer 1 collaboration

Jessica P Roelands 1 collaboration

Brendy E M W van den Akker 1 collaboration

Inge H Briaire-de Bruijn 1 collaboration

Pauline M Wijers-Koster 1 collaboration

Samuel B Polak 1 collaboration

Wilco C Peul 1 collaboration

Robert J P van der Wal 1 collaboration

Judith V M G Bovee 1 collaboration

Lotte E van der Meeren 1 collaboration

Kyra L Dijkstra 1 collaboration

H Kapsenberg 1 collaboration

C van der Keur 1 collaboration

Emily F Cornish 1 collaboration

Peter G J Nikkels 1 collaboration

Hehuan Zhu 1 collaboration

Eiman I Ahmed 1 collaboration

Imke Stouten 1 collaboration

Rachel Hoorntje 1 collaboration

Ronald L P van Vlierberghe 1 collaboration

Xin Lei 1 collaboration

Rob A E M Tollenaar 1 collaboration

Alexander L Vahrmeijer 1 collaboration

Davide Bedognetti 1 collaboration

Wouter R L Hendrickx 1 collaboration

Peter J K Kuppen 1 collaboration

Rick Ursem 1 collaboration

Martin Giera 1 collaboration

Bart Everts 1 collaboration

Bram Heijs 1 collaboration

Boyd Kenkhuis 1 collaboration

Thomas Hollt 1 collaboration

Sara Rocha 1 collaboration

Afonso P Basto 1 collaboration

Sara P Teles 1 collaboration

Maria M Azevedo 1 collaboration

Gilza Gonçalves 1 collaboration

Irene Gullo 1 collaboration

Gabriela M Almeida 1 collaboration

Joaquín J Maqueda 1 collaboration

Marta I Oliveira 1 collaboration

Fátima Carneiro 1 collaboration

João T Barata 1 collaboration

Luís Graça 1 collaboration

Joana Carvalho 1 collaboration

Carla Oliveira 1 collaboration

Eileen Reidy 1 collaboration

Ana Ramalheiro 1 collaboration

A Marijne Heeren 1 collaboration

Alexander Vahrmeijer 1 collaboration

Ekaterina S Jordanova 1 collaboration

Nannan Guo 1 collaboration

Laura F Ouboter 1 collaboration

Andrea E van der Meulen 1 collaboration

Na Li 1 collaboration

Anita van der Zwan 1 collaboration

Hanneke Kapsenberg 1 collaboration

Sanne H Hendriks 1 collaboration

Carin van der Keur 1 collaboration

Lotte J Verleng 1 collaboration

Antonis Somarakis 1 collaboration

Lotte van der Meeren 1 collaboration

Geert Haasnoot 1 collaboration

Arnoud H de Ru 1 collaboration

Rayman T N Tjokrodirijo 1 collaboration

Natasja I Janssen 1 collaboration

Linda de Bruin 1 collaboration

Pita de Kok 1 collaboration

George M C Janssen 1 collaboration

Ellen H W Kapiteijn 1 collaboration

Peter A van Veelen 1 collaboration

Saskia J Santegoets 1 collaboration

Gregor Sturm 1 collaboration

Pornpimol Charoentong 1 collaboration

Francesca Finotello 1 collaboration

Zlatko Trajanoski 1 collaboration

Sylvia L van Egmond 1 collaboration

Dana A M Mustafa 1 collaboration

Marij J P Welters 1 collaboration

Giulia Trimaglio 1 collaboration

Tamara Sneperger 1 collaboration

Benjamin B A Raymond 1 collaboration

Nelly Gilles 1 collaboration

Emmanuelle Näser 1 collaboration

Marie Locard-Paulet 1 collaboration

Romain Ecalard 1 collaboration

Naoki Matsumoto 1 collaboration

André Colom 1 collaboration

Myriam Habch 1 collaboration

Nathalie Vergnolle 1 collaboration

Christel Devaud 1 collaboration

Olivier Neyrolles 1 collaboration

Yoann Rombouts 1 collaboration

Paula Niewold 1 collaboration

Frank A W Verreck 1 collaboration

Tom H M Ottenhoff 1 collaboration

Simone A Joosten 1 collaboration