Lauren Gentles

Affiliations

Department of Microbiology, University of Washington, Seattle, WA, 98195, USA.
Division of Basic Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, 98109, USA.

Publications (8)

Evaluating the potential of kinase inhibitors to suppress DNA repair and sensitise ovarian cancer cells to PARP inhibitors.

Biochemical pharmacology

Avec: Asima Mukhopadhyay , Yvette Drew , Elizabeth Matheson , Mo Salehan , Lucy Gentles , Jonathan A Pachter , Nicola J Curtin

Exploring the Frequency of Homologous Recombination DNA Repair Dysfunction in Multiple Cancer Types.

Cancers

Avec: Lucy Gentles , Bojidar Goranov , Elizabeth Matheson , Ashleigh Herriott , Angelika Kaufmann , Sally Hall , Asima Mukhopadhyay , Yvette Drew , Nicola J Curtin , Rachel L O'Donnell

Kappa chain maturation helps drive rapid development of an infant HIV-1 broadly neutralizing antibody lineage.

Nature communications

Avec: Cassandra A Simonich , Laura Doepker , Duncan Ralph , James A Williams , Amrit Dhar , Zak Yaffe , Christopher T Small , Brian Oliver , Vladimir Vigdorovich , Vidya Mangala Prasad , Ruth Nduati , D Noah Sather , Kelly K Lee , Frederick A Matsen Iv , Julie Overbaugh

Broadly neutralizing antibodies target a haemagglutinin anchor epitope.

Nature

Avec: Jenna J Guthmiller , Julianna Han , Henry A Utset , Lei Li , Linda Yu-Ling Lan , Carole Henry , Christopher T Stamper , Meagan McMahon , George O'Dell , Monica L Fernández-Quintero , Alec W Freyn , Fatima Amanat , Olivia Stovicek , Sara T Richey , Alba Torrents de la Peña , Victoria Rosado , Haley L Dugan , Nai-Ying Zheng , Micah E Tepora , Dalia J Bitar , Siriruk Changrob , Shirin Strohmeier , Min Huang , Adolfo García-Sastre , Klaus R Liedl , Jesse D Bloom , Raffael Nachbagauer , Peter Palese , Florian Krammer , Lynda Coughlan , Andrew B Ward , Patrick C Wilson

Integration of computer-aided automated analysis algorithms in the development and validation of immunohistochemistry biomarkers in ovarian cancer.

Journal of clinical pathology

Avec: Lucy Gentles , Rachel Howarth , Won Ji Lee , Sweta Sharma-Saha , Angela Ralte , Nicola Curtin , Yvette Drew , Rachel Louise O'Donnell

Genomic, Transcriptomic, and Functional Alterations in DNA Damage Response Pathways as Putative Biomarkers of Chemotherapy Response in Ovarian Cancer.

Cancers

Avec: Sweta Sharma Saha , Lucy Gentles , Alice Bradbury , Dominik Brecht , Rebecca Robinson , Rachel O'Donnell , Nicola J Curtin , Yvette Drew

The kinetics and durability of antibody and T-cell responses to SARS-CoV-2 in children.

The Journal of infectious diseases

Avec: Megan A Files , Leanne Kehoe , Amanda Adler , Kirsten Lacombe , Jane A Dickerson , Alexander Greninger , Alpana Waghmare , Tarayn Fairlie , Kimberly Pringle , Claire M Midgley , Melissa Briggs Hagen , Janet A Englund , Chetan Seshadri

Deep Mutational Scan of the Highly Conserved Influenza A Virus M1 Matrix Protein Reveals Substantial Intrinsic Mutational Tolerance.

Journal of virology

Avec: Nancy Hom , Jesse D Bloom , Kelly K Lee

Réseau de co-auteurs

Yvette Drew 4 collaborations

Lucy Gentles 4 collaborations

Nicola J Curtin 3 collaborations

Asima Mukhopadhyay 2 collaborations

Elizabeth Matheson 2 collaborations

Kelly K Lee 2 collaborations

Jesse D Bloom 2 collaborations

Mo Salehan 1 collaboration

Jonathan A Pachter 1 collaboration

Bojidar Goranov 1 collaboration

Ashleigh Herriott 1 collaboration

Angelika Kaufmann 1 collaboration

Sally Hall 1 collaboration

Rachel L O'Donnell 1 collaboration

Cassandra A Simonich 1 collaboration

Laura Doepker 1 collaboration

Duncan Ralph 1 collaboration

James A Williams 1 collaboration

Amrit Dhar 1 collaboration

Zak Yaffe 1 collaboration

Christopher T Small 1 collaboration

Brian Oliver 1 collaboration

Vladimir Vigdorovich 1 collaboration

Vidya Mangala Prasad 1 collaboration

Ruth Nduati 1 collaboration

D Noah Sather 1 collaboration

Frederick A Matsen Iv 1 collaboration

Julie Overbaugh 1 collaboration

Jenna J Guthmiller 1 collaboration

Julianna Han 1 collaboration

Henry A Utset 1 collaboration

Lei Li 1 collaboration

Linda Yu-Ling Lan 1 collaboration

Carole Henry 1 collaboration

Christopher T Stamper 1 collaboration

Meagan McMahon 1 collaboration

George O'Dell 1 collaboration

Monica L Fernández-Quintero 1 collaboration

Alec W Freyn 1 collaboration

Fatima Amanat 1 collaboration

Olivia Stovicek 1 collaboration

Sara T Richey 1 collaboration

Alba Torrents de la Peña 1 collaboration

Victoria Rosado 1 collaboration

Haley L Dugan 1 collaboration

Nai-Ying Zheng 1 collaboration

Micah E Tepora 1 collaboration

Dalia J Bitar 1 collaboration

Siriruk Changrob 1 collaboration

Shirin Strohmeier 1 collaboration

Min Huang 1 collaboration

Adolfo García-Sastre 1 collaboration

Klaus R Liedl 1 collaboration

Raffael Nachbagauer 1 collaboration

Peter Palese 1 collaboration

Florian Krammer 1 collaboration

Lynda Coughlan 1 collaboration

Andrew B Ward 1 collaboration

Patrick C Wilson 1 collaboration

Rachel Howarth 1 collaboration

Won Ji Lee 1 collaboration

Sweta Sharma-Saha 1 collaboration

Angela Ralte 1 collaboration

Nicola Curtin 1 collaboration

Rachel Louise O'Donnell 1 collaboration

Sweta Sharma Saha 1 collaboration

Alice Bradbury 1 collaboration

Dominik Brecht 1 collaboration

Rebecca Robinson 1 collaboration

Rachel O'Donnell 1 collaboration

Megan A Files 1 collaboration

Leanne Kehoe 1 collaboration

Amanda Adler 1 collaboration

Kirsten Lacombe 1 collaboration

Jane A Dickerson 1 collaboration

Alexander Greninger 1 collaboration

Alpana Waghmare 1 collaboration

Tarayn Fairlie 1 collaboration

Kimberly Pringle 1 collaboration

Claire M Midgley 1 collaboration

Melissa Briggs Hagen 1 collaboration

Janet A Englund 1 collaboration

Chetan Seshadri 1 collaboration

Nancy Hom 1 collaboration