Laura Baranello

Affiliations

Department of Cell Molecular Biology, Karolinska Institute, Stockholm, Sweden.

Publications (14)

Spatial Chromosome Folding and Active Transcription Drive DNA Fragility and Formation of Oncogenic MLL Translocations.

Molecular cell

Avec: Henrike Johanna Gothe , Britta Annika Maria Bouwman , Eduardo Gade Gusmao , Rossana Piccinno , Giuseppe Petrosino , Sergi Sayols , Oliver Drechsel , Vera Minneker , Natasa Josipovic , Athanasia Mizi , Christian Friberg Nielsen , Eva-Maria Wagner , Shunichi Takeda , Hiroyuki Sasanuma , Damien Francis Hudson , Thomas Kindler , Argyris Papantonis , Nicola Crosetto , Vassilis Roukos

MYC assembles and stimulates topoisomerases 1 and 2 in a "topoisome".

Molecular cell

Avec: Subhendu K Das , Vladislav Kuzin , Donald P Cameron , Suzanne Sanford , Rajiv Kumar Jha , Zuqin Nie , Marta Trullols Rosello , Ronald Holewinski , Thorkell Andresson , Jan Wisniewski , Toyoaki Natsume , David H Price , Brian A Lewis , Fedor Kouzine , David Levens ,

MYCMI-7: A Small MYC-Binding Compound that Inhibits MYC: MAX Interaction and Tumor Growth in a MYC-Dependent Manner.

Cancer research communications

Avec: Alina Castell , Qinzi Yan , Karin Fawkner , Wesam Bazzar , Fan Zhang , Malin Wickström , Mohammad Alzrigat , Marcela Franco , Cecilia Krona , Donald P Cameron , Cecilia Dyberg , Thale Kristin Olsen , Vasiliki Verschut , Linnéa Schmidt , Sheryl Y Lim , Loay Mahmoud , Per Hydbring , Sören Lehmann , Sven Nelander , John Inge Johnsen , Lars-Gunnar Larsson

MYC protein stability is negatively regulated by BRD4.

Proceedings of the National Academy of Sciences of the United States of America

Avec: Ballachanda N Devaiah , Jie Mu , Ben Akman , Sheetal Uppal , Jocelyn D Weissman , Dan Cheng , Zuqin Nie , David Levens , Dinah S Singer

The Epstein-Barr virus deubiquitinating enzyme BPLF1 regulates the activity of topoisomerase II during productive infection.

PLoS pathogens

Avec: Jinlin Li , Noemi Nagy , Jiangnan Liu , Soham Gupta , Teresa Frisan , Thomas Hennig , Donald P Cameron , Maria G Masucci

Topoisomerase 1 activity during mitotic transcription favors the transition from mitosis to G1.

Molecular cell

Avec: Anika Wiegard , Vladislav Kuzin , Donald P Cameron , Jan Grosser , Michele Ceribelli , Rashid Mehmood , Roberto Ballarino , Francesco Valant , Radosław Grochowski , Ivana Karabogdan , Nicola Crosetto , Arne Lindqvist , Anna Helene Bizard , Fedor Kouzine , Toyoaki Natsume ,

Deficiency of Polη in Saccharomyces cerevisiae reveals the impact of transcription on damage-induced cohesion.

PLoS genetics

Avec: Pei-Shang Wu , Jan Grosser , Donald P Cameron , Lena Ström

Control of protein synthesis through mRNA pseudouridylation by dyskerin.

Science advances

Avec: Chiara Pederiva , Davide M Trevisan , Dimitra Peirasmaki , Shan Chen , Sharon A Savage , Ola Larsson , Jernej Ule , Federico Agostini , Marianne Farnebo

Epigenetic control of Topoisomerase 1 activity presents a cancer vulnerability.

bioRxiv : the preprint server for biology

Avec: Tae-Hee Lee , Colina X Qiao , Vladislav Kuzin , Yuepeng Shi , Vijayalalitha Ramanaranayan , Tongyu Wu , Xianzhen Zhou , David Corujo , Marcus Buschbeck , Philipp Oberdoerffer

Analysis of Myc Chromatin Binding by Calibrated ChIP-Seq Approach.

Methods in molecular biology (Clifton, N.J.)

Avec: Donald P Cameron , Vladislav Kuzin ,

TOP1 CAD-seq: A protocol to map catalytically engaged topoisomerase 1 in human cells.

STAR protocols

Avec: Vladislav Kuzin , Anika Wiegard , Donald P Cameron ,

Coinhibition of topoisomerase 1 and BRD4-mediated pause release selectively kills pancreatic cancer via readthrough transcription.

Science advances

Avec: Donald P Cameron , Jan Grosser , Swetlana Ladigan , Vladislav Kuzin , Evanthia Iliopoulou , Anika Wiegard , Hajar Benredjem , Kathryn Jackson , Sven T Liffers , Smiths Lueong , Phyllis F Cheung , Deepak Vangala , Michael Pohl , Richard Viebahn , Christian Teschendorf , Heiner Wolters , Selami Usta , Keyi Geng , Claudia Kutter , Marie Arsenian-Henriksson , Jens T Siveke , Andrea Tannapfel , Wolff Schmiegel , Stephan A Hahn ,

Cyclin A2 localises in the cytoplasm at the S/G2 transition to activate PLK1.

Life science alliance

Avec: Helena Silva Cascales , Kamila Burdova , Anna Middleton , Vladislav Kuzin , Erik Müllers , Henriette Stoy , Libor Macurek , Arne Lindqvist

NEDDylated Cullin 3 mediates the adaptive response to topoisomerase 1 inhibitors.

Science advances

Avec: Alice Meroni , Jan Grosser , Sumedha Agashe , Natasha Ramakrishnan , Jessica Jackson , Priyanka Verma , Alessandro Vindigni

Réseau de co-auteurs

Donald P Cameron 8 collaborations

Vladislav Kuzin 7 collaborations

Jan Grosser 4 collaborations

Anika Wiegard 3 collaborations

Nicola Crosetto 2 collaborations

Zuqin Nie 2 collaborations

Toyoaki Natsume 2 collaborations

Fedor Kouzine 2 collaborations

David Levens 2 collaborations

Arne Lindqvist 2 collaborations

Henrike Johanna Gothe 1 collaboration

Britta Annika Maria Bouwman 1 collaboration

Eduardo Gade Gusmao 1 collaboration

Rossana Piccinno 1 collaboration

Giuseppe Petrosino 1 collaboration

Sergi Sayols 1 collaboration

Oliver Drechsel 1 collaboration

Vera Minneker 1 collaboration

Natasa Josipovic 1 collaboration

Athanasia Mizi 1 collaboration

Christian Friberg Nielsen 1 collaboration

Eva-Maria Wagner 1 collaboration

Shunichi Takeda 1 collaboration

Hiroyuki Sasanuma 1 collaboration

Damien Francis Hudson 1 collaboration

Thomas Kindler 1 collaboration

Argyris Papantonis 1 collaboration

Vassilis Roukos 1 collaboration

Subhendu K Das 1 collaboration

Suzanne Sanford 1 collaboration

Rajiv Kumar Jha 1 collaboration

Marta Trullols Rosello 1 collaboration

Ronald Holewinski 1 collaboration

Thorkell Andresson 1 collaboration

Jan Wisniewski 1 collaboration

David H Price 1 collaboration

Brian A Lewis 1 collaboration

Alina Castell 1 collaboration

Qinzi Yan 1 collaboration

Karin Fawkner 1 collaboration

Wesam Bazzar 1 collaboration

Fan Zhang 1 collaboration

Malin Wickström 1 collaboration

Mohammad Alzrigat 1 collaboration

Marcela Franco 1 collaboration

Cecilia Krona 1 collaboration

Cecilia Dyberg 1 collaboration

Thale Kristin Olsen 1 collaboration

Vasiliki Verschut 1 collaboration

Linnéa Schmidt 1 collaboration

Sheryl Y Lim 1 collaboration

Loay Mahmoud 1 collaboration

Per Hydbring 1 collaboration

Sören Lehmann 1 collaboration

Sven Nelander 1 collaboration

John Inge Johnsen 1 collaboration

Lars-Gunnar Larsson 1 collaboration

Ballachanda N Devaiah 1 collaboration

Jie Mu 1 collaboration

Ben Akman 1 collaboration

Sheetal Uppal 1 collaboration

Jocelyn D Weissman 1 collaboration

Dan Cheng 1 collaboration

Dinah S Singer 1 collaboration

Jinlin Li 1 collaboration

Noemi Nagy 1 collaboration

Jiangnan Liu 1 collaboration

Soham Gupta 1 collaboration

Teresa Frisan 1 collaboration

Thomas Hennig 1 collaboration

Maria G Masucci 1 collaboration

Michele Ceribelli 1 collaboration

Rashid Mehmood 1 collaboration

Roberto Ballarino 1 collaboration

Francesco Valant 1 collaboration

Radosław Grochowski 1 collaboration

Ivana Karabogdan 1 collaboration

Anna Helene Bizard 1 collaboration

Pei-Shang Wu 1 collaboration

Lena Ström 1 collaboration

Chiara Pederiva 1 collaboration

Davide M Trevisan 1 collaboration

Dimitra Peirasmaki 1 collaboration

Shan Chen 1 collaboration

Sharon A Savage 1 collaboration

Ola Larsson 1 collaboration

Jernej Ule 1 collaboration

Federico Agostini 1 collaboration

Marianne Farnebo 1 collaboration

Tae-Hee Lee 1 collaboration

Colina X Qiao 1 collaboration

Yuepeng Shi 1 collaboration

Vijayalalitha Ramanaranayan 1 collaboration

Tongyu Wu 1 collaboration

Xianzhen Zhou 1 collaboration

David Corujo 1 collaboration

Marcus Buschbeck 1 collaboration

Philipp Oberdoerffer 1 collaboration

Swetlana Ladigan 1 collaboration

Evanthia Iliopoulou 1 collaboration

Hajar Benredjem 1 collaboration

Kathryn Jackson 1 collaboration

Sven T Liffers 1 collaboration

Smiths Lueong 1 collaboration

Phyllis F Cheung 1 collaboration

Deepak Vangala 1 collaboration

Michael Pohl 1 collaboration

Richard Viebahn 1 collaboration

Christian Teschendorf 1 collaboration

Heiner Wolters 1 collaboration

Selami Usta 1 collaboration

Keyi Geng 1 collaboration

Claudia Kutter 1 collaboration

Marie Arsenian-Henriksson 1 collaboration

Jens T Siveke 1 collaboration

Andrea Tannapfel 1 collaboration

Wolff Schmiegel 1 collaboration

Stephan A Hahn 1 collaboration

Helena Silva Cascales 1 collaboration

Kamila Burdova 1 collaboration

Anna Middleton 1 collaboration

Erik Müllers 1 collaboration

Henriette Stoy 1 collaboration

Libor Macurek 1 collaboration

Alice Meroni 1 collaboration

Sumedha Agashe 1 collaboration

Natasha Ramakrishnan 1 collaboration

Jessica Jackson 1 collaboration

Priyanka Verma 1 collaboration

Alessandro Vindigni 1 collaboration