Lars Viktrup

Affiliations

Eli Lilly & Company, Indianapolis, IN, United States.

Publications (42)

Tanezumab for chronic low back pain: a randomized, double-blind, placebo- and active-controlled, phase 3 study of efficacy and safety.

Pain

Avec: John D Markman , Robert B Bolash , Timothy E McAlindon , Alan J Kivitz , Manuel Pombo-Suarez , Seiji Ohtori , Frank W Roemer , David J Li , Candace Bramson , Christine R West , Kenneth M Verburg

Are pain severity and current pharmacotherapies associated with quality of life, work productivity, and healthcare utilisation for people with osteoarthritis in five large European countries?

Clinical and experimental rheumatology

Avec: Philip G Conaghan , Michael J Doane , Dena Hirschfield Jaffe , Erika Dragon , Lucy Abraham , Andrew G Bushmakin , Joseph C Cappelleri , Serge Perrot

Long-Term Safety and Efficacy of Subcutaneous Tanezumab Versus Nonsteroidal Antiinflammatory Drugs for Hip or Knee Osteoarthritis: A Randomized Trial.

Arthritis & rheumatology (Hoboken, N.J.)

Avec: Marc C Hochberg , John A Carrino , Thomas J Schnitzer , Ali Guermazi , David A Walsh , Alexander White , Satoru Nakajo , Robert J Fountaine , Anne Hickman , Glenn Pixton , Mark T Brown , Christine R West , Kenneth M Verburg

Single and Composite Endpoints of Within-Patient Improvement in Symptoms: Pooled Tanezumab Data in Patients with Osteoarthritis.

Rheumatology and therapy

Avec: Thomas J Schnitzer , Francis Berenbaum , Philip G Conaghan , Robert H Dworkin , Davide Gatti , Ruoyong Yang , Isabelle Davignon , Christine R West , Kenneth M Verburg

Satisfaction with Medications Prescribed for Osteoarthritis: A Cross-Sectional Survey of Patients and Their Physicians in the United States.

Pain and therapy

Avec: Rebecca L Robinson , Thomas J Schnitzer , Sophie Barlow , Mia Berry , Andrew G Bushmakin , Joseph C Cappelleri , Leslie Tive , Jessica Jackson , James Jackson ,

Observed efficacy and clinically important improvements in participants with osteoarthritis treated with subcutaneous tanezumab: results from a 56-week randomized NSAID-controlled study.

Arthritis research & therapy

Avec: Tuhina Neogi , David J Hunter , Melvin Churchill , Ivan Shirinsky , Alexander White , Ali Guermazi , Masanari Omata , Robert J Fountaine , Glenn Pixton , Mark T Brown , Christine R West , Kenneth M Verburg

WOMAC Meaningful Within-patient Change: Results From 3 Studies of Tanezumab in Patients With Moderate-to-severe Osteoarthritis of the Hip or Knee.

The Journal of rheumatology

Avec: Philip G Conaghan , Robert H Dworkin , Thomas J Schnitzer , Francis Berenbaum , Andrew G Bushmakin , Joseph C Cappelleri , Lucy Abraham

Burden of chronic low back pain: Association with pain severity and prescription medication use in five large European countries.

Pain practice : the official journal of World Institute of Pain

Avec: Serge Perrot , Michael J Doane , Dena H Jaffe , Erika Dragon , Lucy Abraham , Andrew G Bushmakin , Joseph C Cappelleri , Philip G Conaghan

Subcutaneous tanezumab for osteoarthritis: Is the early improvement in pain and function meaningful and sustained?

European journal of pain (London, England)

Avec: Francis Berenbaum , Richard Langford , Serge Perrot , Kenji Miki , Francisco J Blanco , Takaharu Yamabe , Naoki Isogawa , Rod Junor , William Carey , Christine R West , Mark T Brown , Kenneth M Verburg

Neurological safety of subcutaneous tanezumab versus NSAID in patients with osteoarthritis.

Journal of the neurological sciences

Avec: Mark T Brown , Paola Sandroni , Phillip A Low , Kenneth C Gorson , David J Hunter , Glenn C Pixton , Robert J Fountaine , Christine R West , Kenneth M Verburg

Effect size varies based on calculation method and may affect interpretation of treatment effect: an illustration using randomised clinical trials in osteoarthritis.

Advances in rheumatology (London, England)

Avec: Thomas J Schnitzer , Philip G Conaghan , Francis Berenbaum , Lucy Abraham , Joseph C Cappelleri , Andrew G Bushmakin , Ruoyong Yang , Mark T Brown

The not so hidden impact of interictal burden in migraine: A narrative review.

Frontiers in neurology

Avec: Maurice Vincent , Robert A Nicholson , Michael H Ossipov , Bert B Vargas

Opioid Prescribing for Osteoarthritis: Cross-Sectional Survey among Primary Care Physicians, Rheumatologists, and Orthopaedic Surgeons.

Journal of clinical medicine

Avec: Thomas J Schnitzer , Rebecca L Robinson , Joseph C Cappelleri , Andrew G Bushmakin , Leslie Tive , Mia Berry , Chloe Walker , James Jackson

Patients' Experiences During the Long Journey Before Initiating Migraine Prevention with a Calcitonin Gene-Related Peptide (CGRP) Monoclonal Antibody (mAb).

Pain and therapy

Avec: Elizabeth Seng , Christian Lampl , William R Lenderking , Hayley Karn , Margaret Hoyt , Gilwan Kim , Dustin Ruff , Michael H Ossipov , Maurice Vincent

Onset and maintenance of efficacy of subcutaneous tanezumab in patients with moderate to severe osteoarthritis of the knee or hip: A 16-week dose-titration study.

Seminars in arthritis and rheumatism

Avec: Thomas J Schnitzer , Arifulla Khan , Louis Bessette , Isabelle Davignon , Mark T Brown , Glenn Pixton , William R Prucka , Leslie Tive , Christine R West

Nerve Growth Factor Signaling and Its Contribution to Pain.

Journal of pain research

Avec: Philip A Barker , Patrick Mantyh , Lars Arendt-Nielsen , Leslie Tive

Efficacy and safety of tadalafil 5 mg once-daily in Asian men with both lower urinary tract symptoms associated with benign prostatic hyperplasia and erectile dysfunction: A phase 3, randomized, double-blind, parallel, placebo- and tamsulosin-controlled study.

International journal of urology : official journal of the Japanese Urological Association

Avec: Zhichao Zhang , Hanzhong Li , Xiaodong Zhang , Yutian Dai , Hyun Jun Park , Bang-Ping Jiann , Peng Li , Ying Lou , Zhangqun Ye ,

Factors associated with physician-reported treatment status of patients with osteoarthritis pain.

BMC musculoskeletal disorders

Avec: Thomas J Schnitzer , Rebecca L Robinson , Leslie Tive , Joseph C Cappelleri , Andrew G Bushmakin , James Jackson , Mia Berry , Sophie Barlow , Chloe Walker ,

Reliability of Wearable Sensors for Assessing Gait and Chair Stand Function at Home in People With Knee Osteoarthritis.

Arthritis care & research

Avec: Michael J Rose , Tuhina Neogi , Brian Friscia , Kaveh A Torabian , Michael P LaValley , Mary Gheller , Lukas Adamowicz , Pirinka Georgiev , Charmaine Demanuele , Paul W Wacnik , Deepak Kumar

Predicting Treatment Responses in Patients With Osteoarthritis: Results From Two Phase III Tanezumab Randomized Clinical Trials.

Clinical pharmacology and therapeutics

Avec: Luana Colloca , Robert H Dworkin , John T Farrar , Leslie Tive , Jiyue Yang , Gorana Dasic , Christine R West , Ed Whalen , Mark T Brown , Steven A Gilbert , Kenneth M Verburg

Treatment patterns of galcanezumab versus standard of care preventive migraine medications over 24 months: a US retrospective claims study.

Current medical research and opinion

Avec: Oralee J Varnado , Michelle Vu , Erin K Buysman , Gilwan Kim , Gayle Allenback , Margaret Hoyt , Helen Trenz , Feng Cao ,

A 3-year follow-up study of outcomes associated with patterns of traditional acute and preventive migraine treatment: An administrative claims-based cohort study in the United States.

Headache

Avec: Shivang Joshi , Andrew Spargo , Margaret Hoyt , Tommaso Panni , Gilwan Kim , Anthony Hasan , Yan Yun Liu , Armen Zakharyan

Subcutaneous tanezumab for osteoarthritis of the hip or knee: efficacy and safety results from a 24-week randomised phase III study with a 24-week follow-up period.

Annals of the rheumatic diseases

Avec: Francis Berenbaum , Francisco J Blanco , Ali Guermazi , Kenji Miki , Takaharu Yamabe , Rod Junor , William Carey , Mark T Brown , Christine R West , Kenneth M Verburg

Patient preferences for osteoarthritis pain and chronic low back pain treatments in the United States: a discrete-choice experiment.

Osteoarthritis and cartilage

Avec: D Turk , M Boeri , L Abraham , J Atkinson , A G Bushmakin , J C Cappelleri , B Hauber , K Klein , L Russo , L Viktrup , D Walsh

Effect of Tanezumab on Joint Pain, Physical Function, and Patient Global Assessment of Osteoarthritis Among Patients With Osteoarthritis of the Hip or Knee: A Randomized Clinical Trial.

JAMA

Avec: Thomas J Schnitzer , Richard Easton , Shirley Pang , Dennis J Levinson , Glenn Pixton , Isabelle Davignon , Mark T Brown , Christine R West , Kenneth M Verburg

Multimodal Treatment Patterns for Osteoarthritis and Their Relationship to Patient-Reported Pain Severity: A Cross-Sectional Survey in the United States.

Journal of pain research

Avec: Srinivas R Nalamachu , Rebecca L Robinson , Joseph C Cappelleri , Andrew G Bushmakin , Leslie Tive , Jennifer Mellor , Niall Hatchell , James Jackson

General Safety and Tolerability of Subcutaneous Tanezumab for Osteoarthritis: A Pooled Analysis of Three Randomized, Placebo-Controlled Trials.

Arthritis care & research

Avec: Francis Berenbaum , Thomas J Schnitzer , Alan J Kivitz , Anne Hickman , Glenn Pixton , Mark T Brown , Isabelle Davignon , Christine R West

Impact of osteoarthritis disease severity on treatment patterns and healthcare resource use: analysis of real-world data.

Scandinavian journal of rheumatology

Avec: P G Conaghan , L Abraham , L Viktrup , J C Cappelleri , C Beck , A G Bushmakin , M Berry , J Jackson

Treating osteoarthritis pain: mechanisms of action of acetaminophen, nonsteroidal anti-inflammatory drugs, opioids, and nerve growth factor antibodies.

Postgraduate medicine

Avec: Yvonne D'Arcy , Patrick Mantyh , Tony Yaksh , Sean Donevan , Jerry Hall , Mojgan Sadrarhami ,

Opioids for Osteoarthritis: Cross-Sectional Survey of Patient Perspectives and Satisfaction.

Journal of clinical medicine

Avec: Thomas J Schnitzer , Rebecca L Robinson , Joseph C Cappelleri , Andrew G Bushmakin , Leslie Tive , Mia Berry , Chloe Walker , James Jackson

Health care resource utilization and direct costs incurred over 24 months after initiating galcanezumab or standard-of-care preventive migraine treatments in the United States.

Journal of managed care & specialty pharmacy

Avec: Oralee J Varnado , Michelle Vu , Erin Buysman , Gilwan Kim , Gayle Allenback , Margaret Hoyt , Helen Trenz , Feng Cao ,

Nerve growth factor antibody for the treatment of osteoarthritis pain and chronic low-back pain: mechanism of action in the context of efficacy and safety.

Pain

Avec: Martin Schmelz , Patrick Mantyh , Anne-Marie Malfait , John Farrar , Tony Yaksh , Leslie Tive ,

Pain severity and healthcare resource utilization in patients with osteoarthritis in the United States.

Postgraduate medicine

Avec: Sri Nalamachu , Rebecca L Robinson , Joseph C Cappelleri , Andrew G Bushmakin , Leslie Tive , Jennifer Mellor , Niall Hatchell , James Jackson

Gender, age, disease severity, body mass index and diabetes may not affect response to subcutaneous tanezumab in patients with osteoarthritis after 16 weeks of treatment. A subgroup analysis of placebo-controlled trials.

International journal of clinical practice

Avec: Francis Berenbaum , Thomas Schnitzer , Alan Kivitz , Elizabeth Johnston , Ruoyong Yang , Ed Whalen , Leslie Tive , David Semel

Postoperative Outcome of Patients Who Underwent Total Joint Replacement During the Tanezumab Phase 3 Osteoarthritis Development Program: A 24-Week Observational Study.

Surgical technology international

Avec: Michael A Mont , John A Carrino , Mary Anne Nemeth , Aimee Burr , Takaharu Yamabe , Mark T Brown , Christine R West , Kenneth M Verburg

Exploring patient preference heterogeneity for pharmacological treatments for chronic pain: A latent class analysis.

European journal of pain (London, England)

Avec: David A Walsh , Marco Boeri , Lucy Abraham , Jo Atkinson , Andrew G Bushmakin , Joseph C Cappelleri , Brett Hauber , Kathleen Klein , Leo Russo , Dennis Turk

Impact of tanezumab on health status, non-work activities and work productivity in adults with moderate-to-severe osteoarthritis.

BMC musculoskeletal disorders

Avec: Philip G Conaghan , Lucy Abraham , Paul Cislo

Characterizing 16-Week Responder Profiles Using Group-Based Trajectory Modeling in Over 4300 Clinical Trial Participants Receiving Pharmaceutical Treatment for Moderate to Severe Osteoarthritis.

Advances in therapy

Avec: Thomas J Schnitzer , Gianluca Bonfanti , Joanna Atkinson , Sean Donevan , Joana Barroso , Edward Whalen , Roger A Edwards

Clinical Meaningfulness of Response to Tanezumab in Patients with Chronic Low Back Pain: Analysis From a 56-Week, Randomized, Placebo- and Tramadol-Controlled, Phase 3 Trial.

Pain and therapy

Avec: John D Markman , Thomas J Schnitzer , Serge Perrot , Said R Beydoun , Seiji Ohtori , Ruoyong Yang , Candace Bramson , Christine R West , Kenneth M Verburg

Characterization of adverse joint outcomes in patients with osteoarthritis treated with subcutaneous tanezumab.

Osteoarthritis and cartilage

Avec: John A Carrino , Timothy E McAlindon , Tom J Schnitzer , Ali Guermazi , Marc C Hochberg , Philip G Conaghan , Mark T Brown , Aimee Burr , Robert J Fountaine , Glenn C Pixton , Kenneth M Verburg , Christine R West

Peripheral Nerve Safety of Nerve Growth Factor Inhibition by Tanezumab: Pooled Analyses of Phase III Clinical Studies in Over 5000 Patients with Osteoarthritis.

Clinical drug investigation

Avec: Mark T Brown , David R Cornblath , Martin Koltzenburg , Kenneth C Gorson , Anne Hickman , Glenn C Pixton , Puneet Gaitonde , Christine R West

A Randomized Placebo-Controlled Trial of the Anti-Nerve Growth Factor Antibody Tanezumab in Subjects With Cancer Pain Due to Bone Metastasis.

The oncologist

Avec: Marie Fallon , Maciej Sopata , Erika Dragon , Mark T Brown , Christine R West , Weihang Bao , Alex Agyemang

Réseau de co-auteurs

Christine R West 16 collaborations

Mark T Brown 14 collaborations

Thomas J Schnitzer 13 collaborations

Kenneth M Verburg 12 collaborations

Andrew G Bushmakin 11 collaborations

Joseph C Cappelleri 11 collaborations

Leslie Tive 11 collaborations

Philip G Conaghan 7 collaborations

Francis Berenbaum 7 collaborations

Lucy Abraham 6 collaborations

Rebecca L Robinson 6 collaborations

James Jackson 6 collaborations

Glenn Pixton 5 collaborations

Serge Perrot 4 collaborations

Ali Guermazi 4 collaborations

Robert J Fountaine 4 collaborations

Ruoyong Yang 4 collaborations

Isabelle Davignon 4 collaborations

Mia Berry 4 collaborations

Margaret Hoyt 4 collaborations

Gilwan Kim 4 collaborations

Erika Dragon 3 collaborations

John A Carrino 3 collaborations

Anne Hickman 3 collaborations

Robert H Dworkin 3 collaborations

Takaharu Yamabe 3 collaborations

Glenn C Pixton 3 collaborations

Chloe Walker 3 collaborations

Patrick Mantyh 3 collaborations

John D Markman 2 collaborations

Timothy E McAlindon 2 collaborations

Alan J Kivitz 2 collaborations

Seiji Ohtori 2 collaborations

Candace Bramson 2 collaborations

Michael J Doane 2 collaborations

Marc C Hochberg 2 collaborations

David A Walsh 2 collaborations

Alexander White 2 collaborations

Sophie Barlow 2 collaborations

Tuhina Neogi 2 collaborations

David J Hunter 2 collaborations

Kenji Miki 2 collaborations

Francisco J Blanco 2 collaborations

Rod Junor 2 collaborations

William Carey 2 collaborations

Kenneth C Gorson 2 collaborations

Maurice Vincent 2 collaborations

Michael H Ossipov 2 collaborations

Ed Whalen 2 collaborations

Oralee J Varnado 2 collaborations

Michelle Vu 2 collaborations

Gayle Allenback 2 collaborations

Helen Trenz 2 collaborations

Feng Cao 2 collaborations

L Abraham 2 collaborations

A G Bushmakin 2 collaborations

J C Cappelleri 2 collaborations

L Viktrup 2 collaborations

Jennifer Mellor 2 collaborations

Niall Hatchell 2 collaborations

Tony Yaksh 2 collaborations

Sean Donevan 2 collaborations

Aimee Burr 2 collaborations

Robert B Bolash 1 collaboration

Manuel Pombo-Suarez 1 collaboration

Frank W Roemer 1 collaboration

David J Li 1 collaboration

Dena Hirschfield Jaffe 1 collaboration

Satoru Nakajo 1 collaboration

Davide Gatti 1 collaboration

Jessica Jackson 1 collaboration

Melvin Churchill 1 collaboration

Ivan Shirinsky 1 collaboration

Masanari Omata 1 collaboration

Dena H Jaffe 1 collaboration

Richard Langford 1 collaboration

Naoki Isogawa 1 collaboration

Paola Sandroni 1 collaboration

Phillip A Low 1 collaboration

Robert A Nicholson 1 collaboration

Bert B Vargas 1 collaboration

Elizabeth Seng 1 collaboration

Christian Lampl 1 collaboration

William R Lenderking 1 collaboration

Hayley Karn 1 collaboration

Dustin Ruff 1 collaboration

Arifulla Khan 1 collaboration

Louis Bessette 1 collaboration

William R Prucka 1 collaboration

Philip A Barker 1 collaboration

Lars Arendt-Nielsen 1 collaboration

Zhichao Zhang 1 collaboration

Hanzhong Li 1 collaboration

Xiaodong Zhang 1 collaboration

Yutian Dai 1 collaboration

Hyun Jun Park 1 collaboration

Bang-Ping Jiann 1 collaboration

Peng Li 1 collaboration

Ying Lou 1 collaboration

Zhangqun Ye 1 collaboration

Michael J Rose 1 collaboration

Brian Friscia 1 collaboration

Kaveh A Torabian 1 collaboration

Michael P LaValley 1 collaboration

Mary Gheller 1 collaboration

Lukas Adamowicz 1 collaboration

Pirinka Georgiev 1 collaboration

Charmaine Demanuele 1 collaboration

Paul W Wacnik 1 collaboration

Deepak Kumar 1 collaboration

Luana Colloca 1 collaboration

John T Farrar 1 collaboration

Jiyue Yang 1 collaboration

Gorana Dasic 1 collaboration

Steven A Gilbert 1 collaboration

Erin K Buysman 1 collaboration

Shivang Joshi 1 collaboration

Andrew Spargo 1 collaboration

Tommaso Panni 1 collaboration

Anthony Hasan 1 collaboration

Yan Yun Liu 1 collaboration

Armen Zakharyan 1 collaboration

D Turk 1 collaboration

M Boeri 1 collaboration

J Atkinson 1 collaboration

B Hauber 1 collaboration

K Klein 1 collaboration

L Russo 1 collaboration

D Walsh 1 collaboration

Richard Easton 1 collaboration

Shirley Pang 1 collaboration

Dennis J Levinson 1 collaboration

Srinivas R Nalamachu 1 collaboration

P G Conaghan 1 collaboration

C Beck 1 collaboration

M Berry 1 collaboration

J Jackson 1 collaboration

Yvonne D'Arcy 1 collaboration

Jerry Hall 1 collaboration

Mojgan Sadrarhami 1 collaboration

Erin Buysman 1 collaboration

Martin Schmelz 1 collaboration

Anne-Marie Malfait 1 collaboration

John Farrar 1 collaboration

Sri Nalamachu 1 collaboration

Thomas Schnitzer 1 collaboration

Alan Kivitz 1 collaboration

Elizabeth Johnston 1 collaboration

David Semel 1 collaboration

Michael A Mont 1 collaboration

Mary Anne Nemeth 1 collaboration

Marco Boeri 1 collaboration

Jo Atkinson 1 collaboration

Brett Hauber 1 collaboration

Kathleen Klein 1 collaboration

Leo Russo 1 collaboration

Dennis Turk 1 collaboration

Paul Cislo 1 collaboration

Gianluca Bonfanti 1 collaboration

Joanna Atkinson 1 collaboration

Joana Barroso 1 collaboration

Edward Whalen 1 collaboration

Roger A Edwards 1 collaboration

Said R Beydoun 1 collaboration

Tom J Schnitzer 1 collaboration

David R Cornblath 1 collaboration

Martin Koltzenburg 1 collaboration

Puneet Gaitonde 1 collaboration

Marie Fallon 1 collaboration

Maciej Sopata 1 collaboration

Weihang Bao 1 collaboration

Alex Agyemang 1 collaboration