Léa N C Rochet

Affiliations

University College London, Chemistry, UNITED KINGDOM.

Publications (10)

Macrocyclic Dual-Locked "Turn-On" Drug for Selective and Traceless Release in Cancer Cells.

Angewandte Chemie (International ed. in English)

Avec: Dominik Schauenburg , Bingjie Gao , Darijan Schüler , Jaime A S Coelho , David Y W Ng , Vijay Chudasama , Seah Ling Kuan , Tanja Weil

Hydrogel Cross-Linking via Thiol-Reactive Pyridazinediones.

Biomacromolecules

Avec: Calise Bahou , Richard J Spears , Angela M Ramírez Rosales , Lydia J Barber , Ksenia S Stankevich , Juliana F Miranda , Tobias C Butcher , Adam M Kerrigan , Vlado K Lazarov , William Grey , Vijay Chudasama , Christopher D Spicer

A novel thiol-labile cysteine protecting group for peptide synthesis based on a pyridazinedione (PD) scaffold.

Chemical communications (Cambridge, England)

Avec: Richard J Spears , Clíona McMahon , Monika Shamsabadi , Calise Bahou , Ioanna A Thanasi , Nafsika Forte , Fabien Thoreau , James R Baker , Vijay Chudasama

Modular Synthesis of Semiconducting Graft Copolymers to Achieve "Clickable" Fluorescent Nanoparticles with Long Circulation and Specific Cancer Targeting.

Advanced materials (Deerfield Beach, Fla.)

Avec: Adam Creamer , Alessandra Lo Fiego , Alice Agliano , Lino Prados-Martin , Håkon Høgset , Adrian Najer , Daniel A Richards , Jonathan P Wojciechowski , James E J Foote , Nayoung Kim , Amy Monahan , Jiaqing Tang , André Shamsabadi , Ioanna A Thanasi , Laura R de la Ballina , Charlotte L Rapley , Stephen Turnock , Elizabeth A Love , Laurence Bugeon , Margaret J Dallman , Martin Heeney , Gabriela Kramer-Marek , Vijay Chudasama , Federico Fenaroli , Molly M Stevens

Glutamine-walking: Creating reactive substrates for transglutaminase-mediated protein labeling.

Methods in enzymology

Avec: Lukas Deweid , Adem Hadjabdelhafid-Parisien , Kiana Lafontaine , Harald Kolmar , Joelle N Pelletier

Rapid Access to Potent Bispecific T Cell Engagers Using Biogenic Tyrosine Click Chemistry.

Bioconjugate chemistry

Avec: Irene Shajan , Shannon R Tracey , Bianka Jackowska , Rania Benazza , Oscar Hernandez-Alba , Sarah Cianférani , Christopher J Scott , Floris L van Delft , Vijay Chudasama , Bauke Albada

Enabling the formation of native mAb, Fab' and Fc-conjugates using a bis-disulfide bridging reagent to achieve tunable payload-to-antibody ratios (PARs).

Chemical science

Avec: Fabien Thoreau , James R Baker , Vijay Chudasama

Modular Chemical Construction of IgG-like Mono- and Bispecific Synthetic Antibodies (SynAbs).

ACS central science

Avec: Fabien Thoreau , Peter A Szijj , Michelle K Greene , Ioanna A Thanasi , Jaine K Blayney , Antoine Maruani , James R Baker , Christopher J Scott , Vijay Chudasama

Use of pyridazinediones for tuneable and reversible covalent cysteine modification applied to peptides, proteins and hydrogels.

Chemical science

Avec: Calise Bahou , Jonathan P Wojciechowski , Ilias Koutsopetras , Phyllida Britton , Richard J Spears , Ioanna A Thanasi , Baihao Shao , Lisha Zhong , Dejan-Krešimir Bučar , Abil E Aliev , Michael J Porter , Molly M Stevens , James R Baker , Vijay Chudasama

Modular Semisynthetic Approach to Generate T Cell-Dependent Bispecific Constructs from Recombinant IgG1 Antibodies.

Bioconjugate chemistry

Avec: Irene Shajan , Shannon R Tracey , Rania Benazza , Bianka Jackowska , Oscar Hernandez-Alba , Sarah Cianférani , Christopher J Scott , Floris L van Delft , Vijay Chudasama , Bauke Albada

Réseau de co-auteurs

Vijay Chudasama 9 collaborations

Ioanna A Thanasi 4 collaborations

James R Baker 4 collaborations

Calise Bahou 3 collaborations

Richard J Spears 3 collaborations

Fabien Thoreau 3 collaborations

Christopher J Scott 3 collaborations

Jonathan P Wojciechowski 2 collaborations

Molly M Stevens 2 collaborations

Irene Shajan 2 collaborations

Shannon R Tracey 2 collaborations

Bianka Jackowska 2 collaborations

Rania Benazza 2 collaborations

Oscar Hernandez-Alba 2 collaborations

Sarah Cianférani 2 collaborations

Floris L van Delft 2 collaborations

Bauke Albada 2 collaborations

Dominik Schauenburg 1 collaboration

Bingjie Gao 1 collaboration

Darijan Schüler 1 collaboration

Jaime A S Coelho 1 collaboration

David Y W Ng 1 collaboration

Seah Ling Kuan 1 collaboration

Tanja Weil 1 collaboration

Angela M Ramírez Rosales 1 collaboration

Lydia J Barber 1 collaboration

Ksenia S Stankevich 1 collaboration

Juliana F Miranda 1 collaboration

Tobias C Butcher 1 collaboration

Adam M Kerrigan 1 collaboration

Vlado K Lazarov 1 collaboration

William Grey 1 collaboration

Christopher D Spicer 1 collaboration

Clíona McMahon 1 collaboration

Monika Shamsabadi 1 collaboration

Nafsika Forte 1 collaboration

Adam Creamer 1 collaboration

Alessandra Lo Fiego 1 collaboration

Alice Agliano 1 collaboration

Lino Prados-Martin 1 collaboration

Håkon Høgset 1 collaboration

Adrian Najer 1 collaboration

Daniel A Richards 1 collaboration

James E J Foote 1 collaboration

Nayoung Kim 1 collaboration

Amy Monahan 1 collaboration

Jiaqing Tang 1 collaboration

André Shamsabadi 1 collaboration

Laura R de la Ballina 1 collaboration

Charlotte L Rapley 1 collaboration

Stephen Turnock 1 collaboration

Elizabeth A Love 1 collaboration

Laurence Bugeon 1 collaboration

Margaret J Dallman 1 collaboration

Martin Heeney 1 collaboration

Gabriela Kramer-Marek 1 collaboration

Federico Fenaroli 1 collaboration

Lukas Deweid 1 collaboration

Adem Hadjabdelhafid-Parisien 1 collaboration

Kiana Lafontaine 1 collaboration

Harald Kolmar 1 collaboration

Joelle N Pelletier 1 collaboration

Peter A Szijj 1 collaboration

Michelle K Greene 1 collaboration

Jaine K Blayney 1 collaboration

Antoine Maruani 1 collaboration

Ilias Koutsopetras 1 collaboration

Phyllida Britton 1 collaboration

Baihao Shao 1 collaboration

Lisha Zhong 1 collaboration

Dejan-Krešimir Bučar 1 collaboration

Abil E Aliev 1 collaboration

Michael J Porter 1 collaboration