Kimberly Lapham

Affiliations

Pfizer Worldwide Research and Development, Groton, Connecticut 06340, United States.

Publications (7)

Discovery of High-Affinity Small-Molecule Binders of the Epigenetic Reader YEATS4.

Journal of medicinal chemistry

Avec: Allyn T Londregan , Karlygash Aitmakhanova , James Bennett , Laura J Byrnes , Daniel P Canterbury , Xiayun Cheng , Thomas Christott , Jennifer Clemens , Steven B Coffey , João M Dias , Matthew S Dowling , Gillian Farnie , Oleg Fedorov , Kimberly F Fennell , Vicki Gamble , Carina Gileadi , Charline Giroud , Michael R Harris , Brett D Hollingshead , Kilian Huber , Magdalena Korczynska , Paula M Loria , Arjun Narayanan , Dafydd R Owen , Brigitt Raux , Parag V Sahasrabudhe , Roger B Ruggeri , Laura Díaz Sáez , Ingrid A Stock , Benjamin A Thuma , Andy Tsai , Alison E Varghese

Evaluation of Icotinib as a Potent and Selective Inhibitor of Aldehyde Oxidase for Reaction Phenotyping in Human Hepatocytes.

Drug metabolism and disposition: the biological fate of chemicals

Avec: Lloyd Wei Tat Tang , Ethan DaSilva , R Scott Obach

Drug metabolism and disposition: the biological fate of chemicals

Avec: Nicholas Ferguson , Mark Niosi , Theunis C Goosen

Evidence-based strategies for the characterisation of human drug and chemical glucuronidation in vitro and UDP-glucuronosyltransferase reaction phenotyping.

Pharmacology & therapeutics

Avec: John O Miners , Andrew Rowland , Jonathan J Novak , Theunis C Goosen

Global Portrait of Protein Targets of Metabolites of the Neurotoxic Compound BIA 10-2474.

ACS chemical biology

Avec: Zhen Huang , Daisuke Ogasawara , Uthpala I Seneviratne , Armand B Cognetta , Christopher W Am Ende , Deane M Nason , John Litchfield , Douglas S Johnson , Benjamin F Cravatt

In Vitro Characterization of Ertugliflozin Metabolism by UDP-Glucuronosyltransferase and Cytochrome P450 Enzymes.

Drug metabolism and disposition: the biological fate of chemicals

Avec: Ernesto Callegari , Julie Cianfrogna , Jian Lin , Mark Niosi , Christine C Orozco , Raman Sharma , Theunis C Goosen

UGT2B10 is the Major UDP-Glucuronosyltransferase 2B Isoform Involved in the Metabolism of Lamotrigine and is Implicated in the Drug-Drug Interaction with Valproic Acid.

The AAPS journal

Avec: Lloyd Wei Tat Tang , Theunis C Goosen

Réseau de co-auteurs

Theunis C Goosen 4 collaborations

Lloyd Wei Tat Tang 2 collaborations

Mark Niosi 2 collaborations

Allyn T Londregan 1 collaboration

Karlygash Aitmakhanova 1 collaboration

James Bennett 1 collaboration

Laura J Byrnes 1 collaboration

Daniel P Canterbury 1 collaboration

Xiayun Cheng 1 collaboration

Thomas Christott 1 collaboration

Jennifer Clemens 1 collaboration

Steven B Coffey 1 collaboration

João M Dias 1 collaboration

Matthew S Dowling 1 collaboration

Gillian Farnie 1 collaboration

Oleg Fedorov 1 collaboration

Kimberly F Fennell 1 collaboration

Vicki Gamble 1 collaboration

Carina Gileadi 1 collaboration

Charline Giroud 1 collaboration

Michael R Harris 1 collaboration

Brett D Hollingshead 1 collaboration

Kilian Huber 1 collaboration

Magdalena Korczynska 1 collaboration

Paula M Loria 1 collaboration

Arjun Narayanan 1 collaboration

Dafydd R Owen 1 collaboration

Brigitt Raux 1 collaboration

Parag V Sahasrabudhe 1 collaboration

Roger B Ruggeri 1 collaboration

Laura Díaz Sáez 1 collaboration

Ingrid A Stock 1 collaboration

Benjamin A Thuma 1 collaboration

Andy Tsai 1 collaboration

Alison E Varghese 1 collaboration

Ethan DaSilva 1 collaboration

R Scott Obach 1 collaboration

Nicholas Ferguson 1 collaboration

John O Miners 1 collaboration

Andrew Rowland 1 collaboration

Jonathan J Novak 1 collaboration

Zhen Huang 1 collaboration

Daisuke Ogasawara 1 collaboration

Uthpala I Seneviratne 1 collaboration

Armand B Cognetta 1 collaboration

Christopher W Am Ende 1 collaboration

Deane M Nason 1 collaboration

John Litchfield 1 collaboration

Douglas S Johnson 1 collaboration

Benjamin F Cravatt 1 collaboration

Ernesto Callegari 1 collaboration

Julie Cianfrogna 1 collaboration

Jian Lin 1 collaboration

Christine C Orozco 1 collaboration

Raman Sharma 1 collaboration