Ken Grime

Affiliations

Drug Metabolism and Pharmacokinetics, Research and Early Development, Respiratory, Inflammation and Autoimmune (RIA), BioPharmaceuticals R&D, AstraZeneca, 431 83 Gothenburg, Sweden.

Publications (7)

Pulmonary Metabolism of Substrates for Key Drug-Metabolizing Enzymes by Human Alveolar Type II Cells, Human and Rat Lung Microsomes, and the Isolated Perfused Rat Lung Model.

Pharmaceutics

Avec: Katarina Rubin , Pär Ewing , Erica Bäckström , Anna Abrahamsson , Britta Bonn , Satoshi Kamata ,

Improving the Accuracy of Predicted Human Pharmacokinetics: Lessons Learned from the AstraZeneca Drug Pipeline Over Two Decades.

Trends in pharmacological sciences

Avec: Michael Davies , Rhys D O Jones , Rasmus Jansson-Löfmark , Adrian J Fretland , Susanne Winiwarter , Paul Morgan , Dermot F McGinnity

Possible Extraction of Drugs from Lung Tissue During Broncho-alveolar Lavage Suggest Uncertainty in the Procedure's Utility for Quantitative Assessment of Airway Drug Exposure.

Journal of pharmaceutical sciences

Avec: E Bäckström , T Erngren , B-M Fihn , M W Sadiq , W Lindberg , M Fridén , K Grime

Epithelial senescence in idiopathic pulmonary fibrosis is propagated by small extracellular vesicles.

Respiratory research

Avec: Sabha Asghar , Susan Monkley , David J F Smith , Richard J Hewitt , Lynne A Murray , Catherine L Overed-Sayer , Philip L Molyneaux

Proof of lung muscarinic receptor occupancy by tiotropium: Translational Positron Emission Tomography studies in non-human primates and humans.

Frontiers in nuclear medicine (Lausanne, Switzerland)

Avec: Zsolt Cselényi , Aurelija Jucaite , Pär Ewing , Per Stenkrona , Cecilia Kristensson , Peter Johnström , Magnus Schou , Martin Bolin , Christer Halldin , Bengt Larsson , Ulf G Eriksson , Lars Farde

Quantification and reliability of [

EJNMMI research

Avec: Zsolt Cselényi , Aurelija Jucaite , Cecilia Kristensson , Per Stenkrona , Pär Ewing , Andrea Varrone , Peter Johnström , Magnus Schou , Ana Vazquez-Romero , Mohammad Mahdi Moein , Martin Bolin , Jonathan Siikanen , Pär Grybäck , Bengt Larsson , Christer Halldin , Ulf G Eriksson , Lars Farde

Plasma Protein Binding as an Optimizable Parameter for Acidic Drugs.

Drug metabolism and disposition: the biological fate of chemicals

Avec: Philip Gardiner , Rhona J Cox ,

Réseau de co-auteurs

Pär Ewing 3 collaborations

Zsolt Cselényi 2 collaborations

Aurelija Jucaite 2 collaborations

Per Stenkrona 2 collaborations

Cecilia Kristensson 2 collaborations

Peter Johnström 2 collaborations

Magnus Schou 2 collaborations

Martin Bolin 2 collaborations

Christer Halldin 2 collaborations

Bengt Larsson 2 collaborations

Ulf G Eriksson 2 collaborations

Lars Farde 2 collaborations

Katarina Rubin 1 collaboration

Erica Bäckström 1 collaboration

Anna Abrahamsson 1 collaboration

Britta Bonn 1 collaboration

Satoshi Kamata 1 collaboration

Michael Davies 1 collaboration

Rhys D O Jones 1 collaboration

Rasmus Jansson-Löfmark 1 collaboration

Adrian J Fretland 1 collaboration

Susanne Winiwarter 1 collaboration

Paul Morgan 1 collaboration

Dermot F McGinnity 1 collaboration

E Bäckström 1 collaboration

T Erngren 1 collaboration

B-M Fihn 1 collaboration

M W Sadiq 1 collaboration

W Lindberg 1 collaboration

M Fridén 1 collaboration

K Grime 1 collaboration

Sabha Asghar 1 collaboration

Susan Monkley 1 collaboration

David J F Smith 1 collaboration

Richard J Hewitt 1 collaboration

Lynne A Murray 1 collaboration

Catherine L Overed-Sayer 1 collaboration

Philip L Molyneaux 1 collaboration

Andrea Varrone 1 collaboration

Ana Vazquez-Romero 1 collaboration

Mohammad Mahdi Moein 1 collaboration

Jonathan Siikanen 1 collaboration

Pär Grybäck 1 collaboration

Philip Gardiner 1 collaboration

Rhona J Cox 1 collaboration