Kari Wilder-Romans

Affiliations

Department of Radiation Oncology, University of Michigan, Ann Arbor, Michigan.

Publications (22)

Expression of the Androgen Receptor Governs Radiation Resistance in a Subset of Glioblastomas Vulnerable to Antiandrogen Therapy.

Molecular cancer therapeutics

Avec: Christian K Werner , Uchechi J Nna , Hanshi Sun , Joseph Dresser , Ayesha U Kothari , Weihua Zhou , Yangyang Yao , Arvind Rao , Stefanie Stallard , Carl Koschmann , Tarik Bor , Waldemar Debinski , Alexander M Hegedus , Meredith A Morgan , Sriram Venneti , Edwina Baskin-Bey , Daniel E Spratt , Howard Colman , Jann N Sarkaria , Arul M Chinnaiyan , Joel R Eisner , Corey Speers , Theodore S Lawrence , Roy E Strowd , Daniel R Wahl

Purine metabolism regulates DNA repair and therapy resistance in glioblastoma.

Nature communications

Avec: Weihua Zhou , Yangyang Yao , Andrew J Scott , Joseph J Dresser , Christian K Werner , Hanshi Sun , Drew Pratt , Peter Sajjakulnukit , Shuang G Zhao , Mary Davis , Barbara S Nelson , Christopher J Halbrook , Li Zhang , Francesco Gatto , Yoshie Umemura , Angela K Walker , Maureen Kachman , Jann N Sarkaria , Jianping Xiong , Meredith A Morgan , Alnawaz Rehemtualla , Maria G Castro , Pedro Lowenstein , Sriram Chandrasekaran , Theodore S Lawrence , Costas A Lyssiotis , Daniel R Wahl

Rewiring of cortical glucose metabolism fuels human brain cancer growth.

medRxiv : the preprint server for health sciences

Avec: Andrew J Scott , Anjali Mittal , Baharan Meghdadi , Sravya Palavalasa , Abhinav Achreja , Alexandra O'Brien , Ayesha U Kothari , Weihua Zhou , Jie Xu , Angelica Lin , Donna M Edwards , Zhe Wu , Jiane Feng , Anthony C Andren , Li Zhang , Vijay Tarnal , Kimberly A Redic , Nathan Qi , Joshua Fischer , Ethan Yang , Michael S Regan , Sylwia A Stopka , Gerard Baquer , Theodore S Lawrence , Sriram Venneti , Nathalie Y R Agar , Costas A Lyssiotis , Wajd N Al-Holou , Deepak Nagrath , Daniel R Wahl

Functional and Mechanistic Interrogation of BET Bromodomain Degraders for the Treatment of Metastatic Castration-resistant Prostate Cancer.

Clinical cancer research : an official journal of the American Association for Cancer Research

Avec: Steven Kregel , Rohit Malik , Irfan A Asangani , Thekkelnaycke Rajendiran , Lanbo Xiao , Josh N Vo , Tanu Soni , Marcin Cieslik , Ester Fernadez-Salas , Bing Zhou , Xuhong Cao , Corey Speers , Shaomeng Wang , Arul M Chinnaiyan

TTK inhibition radiosensitizes basal-like breast cancer through impaired homologous recombination.

The Journal of clinical investigation

Avec: Benjamin C Chandler , Leah Moubadder , Cassandra L Ritter , Meilan Liu , Meleah Cameron , Amanda Zhang , Andrea M Pesch , Anna R Michmerhuizen , Nicole Hirsh , Marlie Androsiglio , Tanner Ward , Eric Olsen , Yashar S Niknafs , Sofia Merajver , Dafydd G Thomas , Powel H Brown , Theodore S Lawrence , Shyam Nyati , Lori J Pierce , Arul Chinnaiyan , Corey Speers

Androgen and oestrogen receptor co-expression determines the efficacy of hormone receptor-mediated radiosensitisation in breast cancer.

British journal of cancer

Avec: Anna R Michmerhuizen , Lynn M Lerner , Connor Ward , Andrea M Pesch , Amanda Zhang , Rachel Schwartz , Joel R Eisner , James M Rae , Lori J Pierce , Corey W Speers

Tissue of origin dictates GOT1 dependence and confers synthetic lethality to radiotherapy.

Cancer & metabolism

Avec: Barbara S Nelson , Lin Lin , Daniel M Kremer , Cristovão M Sousa , Cecilia Cotta-Ramusino , Amy Myers , Johanna Ramos , Tina Gao , Ilya Kovalenko , Joseph Dresser , Mary Davis , Ho-Joon Lee , Zeribe C Nwosu , Scott Campit , Oksana Mashadova , Brandon N Nicolay , Zachary P Tolstyka , Christopher J Halbrook , Sriram Chandrasekaran , John M Asara , Howard C Crawford , Lewis C Cantley , Alec C Kimmelman , Daniel R Wahl , Costas A Lyssiotis

A Signature That May Be Predictive of Early Versus Late Recurrence After Radiation Treatment for Breast Cancer That May Inform the Biology of Early, Aggressive Recurrences.

International journal of radiation oncology, biology, physics

Avec: Corey Speers , S Laura Chang , Andrea Pesch , Cassandra Ritter , Eric Olsen , Ben Chandler , Leah Moubadder , Meilan Liu , Meleah Cameron , Anna Michmerhuizen , Shuang G Zhao , Shyam Nyati , Harry Bartelink , Felix Y Feng , Lori J Pierce

DNA-Dependent Protein Kinase Drives Prostate Cancer Progression through Transcriptional Regulation of the Wnt Signaling Pathway.

Clinical cancer research : an official journal of the American Association for Cancer Research

Avec: Vishal Kothari , Jonathan F Goodwin , Shuang G Zhao , Justin M Drake , Yi Yin , S Laura Chang , Joseph R Evans , Kristina Gabbara , Emanuela Dylgjeri , Jonathan Chou , Grace Sun , Scott A Tomlins , Rohit Mehra , Kristen Hege , Ellen H Filvaroff , Edward M Schaeffer , R Jeffrey Karnes , David A Quigley , Dana E Rathkopf , Housheng H He , Corey Speers , Daniel E Spratt , Luke A Gilbert , Alan Ashworth , Arul M Chinnaiyan , Ganesh V Raj , Karen E Knudsen , Felix Y Feng

Identification of TP53RK-Binding Protein (TPRKB) Dependency in

Molecular cancer research : MCR

Avec: Moloy T Goswami , Kelly R VanDenBerg , Sumin Han , Lei Lucy Wang , Bhavneet Singh , Travis Weiss , Myles Barlow , Steven Kamberov , Daniel R Rhodes , Felix Y Feng , Scott A Tomlins

Estrogen receptor inhibition mediates radiosensitization of ER-positive breast cancer models.

NPJ breast cancer

Avec: Anna R Michmerhuizen , Lynn M Lerner , Andrea M Pesch , Connor Ward , Rachel Schwartz , Meilan Liu , Charles Nino , Kassidy Jungles , Ruth Azaria , Alexa Jelley , Nicole Zambrana Garcia , Alexis Harold , Amanda Zhang , Bryan Wharram , Daniel F Hayes , James M Rae , Lori J Pierce , Corey W Speers

Seviteronel, a Novel CYP17 Lyase Inhibitor and Androgen Receptor Antagonist, Radiosensitizes AR-Positive Triple Negative Breast Cancer Cells.

Frontiers in endocrinology

Avec: Anna R Michmerhuizen , Benjamin Chandler , Eric Olsen , Leah Moubadder , Meilan Liu , Andrea M Pesch , Amanda Zhang , Cassandra Ritter , S Tanner Ward , Alyssa Santola , Shyam Nyati , James M Rae , Daniel Hayes , Felix Y Feng , Daniel Spratt , Daniel Wahl , Joel Eisner , Lori J Pierce , Corey Speers

Androgen receptor degraders overcome common resistance mechanisms developed during prostate cancer treatment.

Neoplasia (New York, N.Y.)

Avec: Steven Kregel , Chao Wang , Xin Han , Lanbo Xiao , Ester Fernandez-Salas , Pushpinder Bawa , Brooke L McCollum , Ingrid J Apel , Xuhong Cao , Corey Speers , Shaomeng Wang , Arul M Chinnaiyan

Short-term CDK4/6 Inhibition Radiosensitizes Estrogen Receptor-Positive Breast Cancers.

Clinical cancer research : an official journal of the American Association for Cancer Research

Avec: Andrea M Pesch , Nicole H Hirsh , Benjamin C Chandler , Anna R Michmerhuizen , Cassandra L Ritter , Marlie P Androsiglio , Meilan Liu , Christina L Gersch , José M Larios , Lori J Pierce , James M Rae , Corey W Speers

Bcl-xL inhibition radiosensitizes

Cancer research communications

Avec: Andrea M Pesch , Benjamin C Chandler , Anna R Michmerhuizen , Hannah M Carter , Nicole H Hirsh , Meilan Liu , Tanner Ward , Cassandra L Ritter , Charles A Nino , Kassidy M Jungles , Lori J Pierce , James M Rae , Corey W Speers

Adaptive rewiring of purine metabolism promotes treatment resistance in H3K27M-mutant diffuse midline glioma.

Research square

Avec: Erik R Peterson , Peter Sajjakulnukit , Andrew J Scott , Caleb Heaslip , Anthony Andren , Weihua Zhou , Sravya Palavalasa , Navyateja Korimerla , Angelica Lin , Alexandra Obrien , Ayesha Kothari , Zitong Zhao , Li Zhang , Meredith A Morgan , Sriram Venneti , Carl Koschmann , Nada Jabado , Costas A Lyssiotis , Maria G Castro , Daniel R Wahl

PARP1 Inhibition Radiosensitizes Models of Inflammatory Breast Cancer to Ionizing Radiation.

Molecular cancer therapeutics

Avec: Anna R Michmerhuizen , Andrea M Pesch , Leah Moubadder , Benjamin C Chandler , Meleah Cameron , Eric Olsen , Dafydd G Thomas , Amanda Zhang , Nicole Hirsh , Cassandra L Ritter , Meilan Liu , Shyam Nyati , Lori J Pierce , Reshma Jagsi , Corey Speers

Neddylation inactivation represses androgen receptor transcription and inhibits growth, survival and invasion of prostate cancer cells.

Neoplasia (New York, N.Y.)

Avec: Xiaochen Zhou , Sumin Han , Grace Y Sun , Hong Zhu , Xiaoqiang Liu , Mingjia Tan , Gongxian Wang , Felix Y Feng , Yi Sun

Epigenetically defined therapeutic targeting in H3.3G34R/V high-grade gliomas.

Science translational medicine

Avec: Stefan R Sweha , Chan Chung , Siva Kumar Natarajan , Pooja Panwalkar , Matthew Pun , Amer Ghali , Jill Bayliss , Drew Pratt , Anand Shankar , Visweswaran Ravikumar , Arvind Rao , Marcin Cieslik , Andrew J Scott , Daniel R Wahl , Selin Jessa , Claudia L Kleinman , Nada Jabado , Alan Mackay , Chris Jones , Daniel Martinez , Mariarita Santi , Alexander R Judkins , Viveka Nand Yadav , Tingting Qin , Timothy N Phoenix , Carl J Koschmann , Suzanne J Baker , Arul M Chinnaiyan , Sriram Venneti

RB expression confers sensitivity to CDK4/6 inhibitor-mediated radiosensitization across breast cancer subtypes.

JCI insight

Avec: Andrea M Pesch , Nicole H Hirsh , Anna R Michmerhuizen , Kassidy M Jungles , Benjamin C Chandler , Meilan Liu , Lynn M Lerner , Charles A Nino , Connor Ward , Erin F Cobain , Theodore S Lawrence , Lori J Pierce , James M Rae , Corey W Speers

Purine salvage promotes treatment resistance in H3K27M-mutant diffuse midline glioma.

Cancer & metabolism

Avec: Erik R Peterson , Peter Sajjakulnukit , Andrew J Scott , Caleb Heaslip , Anthony Andren , Weihua Zhou , Sravya Palavalasa , Navyateja Korimerla , Angelica Lin , Alexandra O'Brien , Ayesha Kothari , Zitong Zhao , Li Zhang , Meredith A Morgan , Sriram Venneti , Carl Koschmann , Nada Jabado , Costas A Lyssiotis , Maria G Castro , Daniel R Wahl

GTP signaling links metabolism, DNA repair, and responses to genotoxic stress.

Cancer discovery

Avec: Weihua Zhou , Zitong Zhao , Angelica Lin , John Z Yang , Jie Xu , Annabel Yang , Jing Li , Sumeet Solanki , Jennifer M Speth , Natalie Walker , Andrew J Scott , Lu Wang , Bo Wen , Anthony Andren , Li Zhang , Ayesha U Kothari , Yangyang Yao , Erik R Peterson , Navyateja Korimerla , Christian K Werner , Alexander Ullrich , Jessica Liang , Janna Jacobson , Sravya Palavalasa , Alexandra M O'Brien , Ameer L Elaimy , Sean P Ferris , Shuang G Zhao , Jann N Sarkaria , Balazs Gyorffy , Shuqun Zhang , Wajd N Al-Holou , Yoshie Umemura , Meredith A Morgan , Theodore S Lawrence , Costas A Lyssiotis , Marc Peters-Golden , Yatrik M Shah , Daniel R Wahl

Réseau de co-auteurs

Lori J Pierce 9 collaborations

Corey Speers 8 collaborations

Daniel R Wahl 8 collaborations

Meilan Liu 8 collaborations

Andrea M Pesch 8 collaborations

Anna R Michmerhuizen 8 collaborations

Weihua Zhou 6 collaborations

Theodore S Lawrence 6 collaborations

Andrew J Scott 6 collaborations

Costas A Lyssiotis 6 collaborations

James M Rae 6 collaborations

Meredith A Morgan 5 collaborations

Sriram Venneti 5 collaborations

Arul M Chinnaiyan 5 collaborations

Li Zhang 5 collaborations

Benjamin C Chandler 5 collaborations

Amanda Zhang 5 collaborations

Corey W Speers 5 collaborations

Felix Y Feng 5 collaborations

Shuang G Zhao 4 collaborations

Sravya Palavalasa 4 collaborations

Angelica Lin 4 collaborations

Leah Moubadder 4 collaborations

Cassandra L Ritter 4 collaborations

Eric Olsen 4 collaborations

Shyam Nyati 4 collaborations

Christian K Werner 3 collaborations

Ayesha U Kothari 3 collaborations

Yangyang Yao 3 collaborations

Carl Koschmann 3 collaborations

Jann N Sarkaria 3 collaborations

Peter Sajjakulnukit 3 collaborations

Maria G Castro 3 collaborations

Meleah Cameron 3 collaborations

Lynn M Lerner 3 collaborations

Connor Ward 3 collaborations

Nicole H Hirsh 3 collaborations

Erik R Peterson 3 collaborations

Anthony Andren 3 collaborations

Navyateja Korimerla 3 collaborations

Zitong Zhao 3 collaborations

Nada Jabado 3 collaborations

Hanshi Sun 2 collaborations

Joseph Dresser 2 collaborations

Arvind Rao 2 collaborations

Daniel E Spratt 2 collaborations

Joel R Eisner 2 collaborations

Drew Pratt 2 collaborations

Mary Davis 2 collaborations

Barbara S Nelson 2 collaborations

Christopher J Halbrook 2 collaborations

Yoshie Umemura 2 collaborations

Sriram Chandrasekaran 2 collaborations

Alexandra O'Brien 2 collaborations

Jie Xu 2 collaborations

Wajd N Al-Holou 2 collaborations

Steven Kregel 2 collaborations

Lanbo Xiao 2 collaborations

Marcin Cieslik 2 collaborations

Xuhong Cao 2 collaborations

Shaomeng Wang 2 collaborations

Nicole Hirsh 2 collaborations

Tanner Ward 2 collaborations

Dafydd G Thomas 2 collaborations

Rachel Schwartz 2 collaborations

S Laura Chang 2 collaborations

Cassandra Ritter 2 collaborations

Scott A Tomlins 2 collaborations

Sumin Han 2 collaborations

Charles A Nino 2 collaborations

Kassidy M Jungles 2 collaborations

Caleb Heaslip 2 collaborations

Ayesha Kothari 2 collaborations

Uchechi J Nna 1 collaboration

Stefanie Stallard 1 collaboration

Tarik Bor 1 collaboration

Waldemar Debinski 1 collaboration

Alexander M Hegedus 1 collaboration

Edwina Baskin-Bey 1 collaboration

Howard Colman 1 collaboration

Roy E Strowd 1 collaboration

Joseph J Dresser 1 collaboration

Francesco Gatto 1 collaboration

Angela K Walker 1 collaboration

Maureen Kachman 1 collaboration

Jianping Xiong 1 collaboration

Alnawaz Rehemtualla 1 collaboration

Pedro Lowenstein 1 collaboration

Anjali Mittal 1 collaboration

Baharan Meghdadi 1 collaboration

Abhinav Achreja 1 collaboration

Donna M Edwards 1 collaboration

Zhe Wu 1 collaboration

Jiane Feng 1 collaboration

Anthony C Andren 1 collaboration

Vijay Tarnal 1 collaboration

Kimberly A Redic 1 collaboration

Nathan Qi 1 collaboration

Joshua Fischer 1 collaboration

Ethan Yang 1 collaboration

Michael S Regan 1 collaboration

Sylwia A Stopka 1 collaboration

Gerard Baquer 1 collaboration

Nathalie Y R Agar 1 collaboration

Deepak Nagrath 1 collaboration

Rohit Malik 1 collaboration

Irfan A Asangani 1 collaboration

Thekkelnaycke Rajendiran 1 collaboration

Josh N Vo 1 collaboration

Tanu Soni 1 collaboration

Ester Fernadez-Salas 1 collaboration

Bing Zhou 1 collaboration

Marlie Androsiglio 1 collaboration

Yashar S Niknafs 1 collaboration

Sofia Merajver 1 collaboration

Powel H Brown 1 collaboration

Arul Chinnaiyan 1 collaboration

Lin Lin 1 collaboration

Daniel M Kremer 1 collaboration

Cristovão M Sousa 1 collaboration

Cecilia Cotta-Ramusino 1 collaboration

Amy Myers 1 collaboration

Johanna Ramos 1 collaboration

Tina Gao 1 collaboration

Ilya Kovalenko 1 collaboration

Ho-Joon Lee 1 collaboration

Zeribe C Nwosu 1 collaboration

Scott Campit 1 collaboration

Oksana Mashadova 1 collaboration

Brandon N Nicolay 1 collaboration

Zachary P Tolstyka 1 collaboration

John M Asara 1 collaboration

Howard C Crawford 1 collaboration

Lewis C Cantley 1 collaboration

Alec C Kimmelman 1 collaboration

Andrea Pesch 1 collaboration

Ben Chandler 1 collaboration

Anna Michmerhuizen 1 collaboration

Harry Bartelink 1 collaboration

Vishal Kothari 1 collaboration

Jonathan F Goodwin 1 collaboration

Justin M Drake 1 collaboration

Yi Yin 1 collaboration

Joseph R Evans 1 collaboration

Kristina Gabbara 1 collaboration

Emanuela Dylgjeri 1 collaboration

Jonathan Chou 1 collaboration

Grace Sun 1 collaboration

Rohit Mehra 1 collaboration

Kristen Hege 1 collaboration

Ellen H Filvaroff 1 collaboration

Edward M Schaeffer 1 collaboration

R Jeffrey Karnes 1 collaboration

David A Quigley 1 collaboration

Dana E Rathkopf 1 collaboration

Housheng H He 1 collaboration

Luke A Gilbert 1 collaboration

Alan Ashworth 1 collaboration

Ganesh V Raj 1 collaboration

Karen E Knudsen 1 collaboration

Moloy T Goswami 1 collaboration

Kelly R VanDenBerg 1 collaboration

Lei Lucy Wang 1 collaboration

Bhavneet Singh 1 collaboration

Travis Weiss 1 collaboration

Myles Barlow 1 collaboration

Steven Kamberov 1 collaboration

Daniel R Rhodes 1 collaboration

Charles Nino 1 collaboration

Kassidy Jungles 1 collaboration

Ruth Azaria 1 collaboration

Alexa Jelley 1 collaboration

Nicole Zambrana Garcia 1 collaboration

Alexis Harold 1 collaboration

Bryan Wharram 1 collaboration

Daniel F Hayes 1 collaboration

Benjamin Chandler 1 collaboration

S Tanner Ward 1 collaboration

Alyssa Santola 1 collaboration

Daniel Hayes 1 collaboration

Daniel Spratt 1 collaboration

Daniel Wahl 1 collaboration

Joel Eisner 1 collaboration

Chao Wang 1 collaboration

Xin Han 1 collaboration

Ester Fernandez-Salas 1 collaboration

Pushpinder Bawa 1 collaboration

Brooke L McCollum 1 collaboration

Ingrid J Apel 1 collaboration

Marlie P Androsiglio 1 collaboration

Christina L Gersch 1 collaboration

José M Larios 1 collaboration

Hannah M Carter 1 collaboration

Alexandra Obrien 1 collaboration

Reshma Jagsi 1 collaboration

Xiaochen Zhou 1 collaboration

Grace Y Sun 1 collaboration

Hong Zhu 1 collaboration

Xiaoqiang Liu 1 collaboration

Mingjia Tan 1 collaboration

Gongxian Wang 1 collaboration

Yi Sun 1 collaboration

Stefan R Sweha 1 collaboration

Chan Chung 1 collaboration

Siva Kumar Natarajan 1 collaboration

Pooja Panwalkar 1 collaboration

Matthew Pun 1 collaboration

Amer Ghali 1 collaboration

Jill Bayliss 1 collaboration

Anand Shankar 1 collaboration

Visweswaran Ravikumar 1 collaboration

Selin Jessa 1 collaboration

Claudia L Kleinman 1 collaboration

Alan Mackay 1 collaboration

Chris Jones 1 collaboration

Daniel Martinez 1 collaboration

Mariarita Santi 1 collaboration

Alexander R Judkins 1 collaboration

Viveka Nand Yadav 1 collaboration

Tingting Qin 1 collaboration

Timothy N Phoenix 1 collaboration

Carl J Koschmann 1 collaboration

Suzanne J Baker 1 collaboration

Erin F Cobain 1 collaboration

John Z Yang 1 collaboration

Annabel Yang 1 collaboration

Jing Li 1 collaboration

Sumeet Solanki 1 collaboration

Jennifer M Speth 1 collaboration

Natalie Walker 1 collaboration

Lu Wang 1 collaboration

Bo Wen 1 collaboration

Alexander Ullrich 1 collaboration

Jessica Liang 1 collaboration

Janna Jacobson 1 collaboration

Alexandra M O'Brien 1 collaboration

Ameer L Elaimy 1 collaboration

Sean P Ferris 1 collaboration

Balazs Gyorffy 1 collaboration

Shuqun Zhang 1 collaboration

Marc Peters-Golden 1 collaboration

Yatrik M Shah 1 collaboration