K Ziqubu

Publications (35)

Isoorientin ameliorates lipid accumulation by regulating fat browning in palmitate-exposed 3T3-L1 adipocytes.

Metabolism open

Avec: Sithandiwe E Mazibuko-Mbeje , Khanyisani Ziqubu , Phiwayinkosi V Dludla , Luca Tiano , Sonia Silvestri , Patrick Orlando , Thembeka A Nyawo , Johan Louw , Abidemi P Kappo , Christo J F Muller

The Potential Role of Polyphenols in Modulating Mitochondrial Bioenergetics within the Skeletal Muscle: A Systematic Review of Preclinical Models.

Molecules (Basel, Switzerland)

Avec: Sinenhlanhla X H Mthembu , Phiwayinkosi V Dludla , Khanyisani Ziqubu , Tawanda M Nyambuya , Abidemi P Kappo , Evelyn Madoroba , Thembeka A Nyawo , Bongani B Nkambule , Sonia Silvestri , Christo J F Muller , Sithandiwe E Mazibuko-Mbeje

Impact of physical exercise and caloric restriction in patients with type 2 diabetes: Skeletal muscle insulin resistance and mitochondrial dysfunction as ideal therapeutic targets.

Life sciences

Avec: Sinenhlanhla X H Mthembu , Sithandiwe E Mazibuko-Mbeje , Khanyisani Ziqubu , Thembeka A Nyawo , Nnini Obonye , Tawanda M Nyambuya , Bongani B Nkambule , Sonia Silvestri , Luca Tiano , Christo J F Muller , Phiwayinkosi V Dludla

Methylenetetrahydrofolate Reductase Polymorphism (rs1801133) and the Risk of Hypertension among African Populations: A Narrative Synthesis of Literature.

Genes

Avec: Sihle E Mabhida , Babu Muhamed , Jyoti R Sharma , Teke Apalata , Sibusiso Nomatshila , Lawrence Mabasa , Mongi Benjeddou , Charity Masilela , Khanyisani Ziqubu , Samukelisiwe Shabalala , Rabia Johnson

Brown adipose tissue-derived metabolites and their role in regulating metabolism.

Metabolism: clinical and experimental

Avec: Khanyisani Ziqubu , Phiwayinkosi V Dludla , Sihle E Mabhida , Babalwa U Jack , Susanne Keipert , Martin Jastroch , Sithandiwe E Mazibuko-Mbeje

Sarcopenia in a type 2 diabetic state: Reviewing literature on the pathological consequences of oxidative stress and inflammation beyond the neutralizing effect of intracellular antioxidants.

Life sciences

Avec: Ndivhuwo Muvhulawa , Sithandiwe E Mazibuko-Mbeje , Duduzile Ndwandwe , Sonia Silvestri , Khanyisani Ziqubu , Marakiya T Moetlediwa , Sinenhlanhla X H Mthembu , Jeanine L Marnewick , Francois H Van der Westhuizen , Bongani B Nkambule , Albertus K Basson , Luca Tiano , Phiwayinkosi V Dludla

Drug-Induced Liver Injury: Clinical Evidence of N-Acetyl Cysteine Protective Effects.

Oxidative medicine and cellular longevity

Avec: Yonela Ntamo , Khanyisani Ziqubu , Nireshni Chellan , Bongani B Nkambule , Tawanda M Nyambuya , Sithandiwe E Mazibuko-Mbeje , Kwazikwakhe B Gabuza , Fabio Marcheggiani , Luca Tiano , Phiwayinkosi V Dludla

Capsaicin, its clinical significance in patients with painful diabetic neuropathy.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Avec: Phiwayinkosi V Dludla , Bongani B Nkambule , Ilenia Cirilli , Fabio Marcheggiani , Sihle E Mabhida , Khanyisani Ziqubu , Yonela Ntamo , Babalwa Jack , Tawanda M Nyambuya , Sidney Hanser , Sithandiwe E Mazibuko-Mbeje

Detrimental Effects of Lipid Peroxidation in Type 2 Diabetes: Exploring the Neutralizing Influence of Antioxidants.

Antioxidants (Basel, Switzerland)

Avec: Samukelisiwe C Shabalala , Rabia Johnson , Albertus K Basson , Khanyisani Ziqubu , Nokulunga Hlengwa , Sinenhlanhla X H Mthembu , Sihle E Mabhida , Sithandiwe E Mazibuko-Mbeje , Sidney Hanser , Ilenia Cirilli , Luca Tiano , Phiwayinkosi V Dludla

Corrigendum: A review on the antidiabetic properties of

Frontiers in pharmacology

Avec: Fikile T Mthiyane , Phiwayinkosi V Dludla , Khanyisani Ziqubu , Sinenhlanhla X H Mthembu , Ndivhuwo Muvhulawa , Nokulunga Hlengwa , Bongani B Nkambule , Sithandiwe E Mazibuko-Mbeje

An insight into brown/beige adipose tissue whitening, a metabolic complication of obesity with the multifactorial origin.

Frontiers in endocrinology

Avec: Khanyisani Ziqubu , Phiwayinkosi V Dludla , Sinenhlanhla X H Mthembu , Bongani B Nkambule , Sihle E Mabhida , Babalwa U Jack , Tawanda M Nyambuya , Sithandiwe E Mazibuko-Mbeje

Adipokines as a therapeutic target by metformin to improve metabolic function: A systematic review of randomized controlled trials.

Pharmacological research

Avec: Phiwayinkosi V Dludla , Bongani B Nkambule , Sithandiwe E Mazibuko-Mbeje , Tawanda M Nyambuya , Vuyolwethu Mxinwa , Kabelo Mokgalaboni , Khanyisani Ziqubu , Ilenia Cirilli , Fabio Marcheggiani , Johan Louw , Luca Tiano

Orientin Improves Substrate Utilization and the Expression of Major Genes Involved in Insulin Signaling and Energy Regulation in Cultured Insulin-Resistant Liver Cells.

Molecules (Basel, Switzerland)

Avec: Sithandiwe E Mazibuko-Mbeje , Sinenhlanhla X H Mthembu , Andani Tshiitamune , Ndivhuwo Muvhulawa , Fikile T Mthiyane , Khanyisani Ziqubu , Christo J F Muller , Phiwayinkosi V Dludla

Curcumin supplementation improves biomarkers of oxidative stress and inflammation in conditions of obesity, type 2 diabetes and NAFLD: updating the status of clinical evidence.

Food & function

Avec: Kabelo Mokgalaboni , Yonela Ntamo , Khanyisani Ziqubu , Tawanda M Nyambuya , Bongani B Nkambule , Sithandiwe E Mazibuko-Mbeje , Kwazikwakhe B Gabuza , Nireshni Chellan , Luca Tiano , Phiwayinkosi V Dludla

Clinical use of N-acetyl cysteine during liver transplantation: Implications of oxidative stress and inflammation as therapeutic targets.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Avec: Yonela Ntamo , Khanyisani Ziqubu , Nireshni Chellan , Bongani B Nkambule , Tawanda M Nyambuya , Sithandiwe E Mazibuko-Mbeje , Kwazikwakhe B Gabuza , Patrick Orlando , Luca Tiano , Phiwayinkosi V Dludla

Impact of dyslipidemia in the development of cardiovascular complications: Delineating the potential therapeutic role of coenzyme Q

Biochimie

Avec: Sinenhlanhla X H Mthembu , Patrick Orlando , Sonia Silvestri , Khanyisani Ziqubu , Sithandiwe E Mazibuko-Mbeje , Sihle E Mabhida , Tawanda M Nyambuya , Bongani B Nkambule , Christo J F Muller , Albertus K Basson , Luca Tiano , Phiwayinkosi V Dludla

High-sensitivity C-reactive protein among people living with HIV on highly active antiretroviral therapy: a systemic review and meta-analysis.

BMC infectious diseases

Avec: Sihle E Mabhida , Zandile J Mchiza , Kabelo Mokgalaboni , Sidney Hanser , Joel Choshi , Haskly Mokoena , Khanyisani Ziqubu , Charity Masilela , Bongani B Nkambule , Duduzile E Ndwandwe , André P Kengne , Phiwayinkosi V Dludla

Impact of Isoorientin on Metabolic Activity and Lipid Accumulation in Differentiated Adipocytes.

Molecules (Basel, Switzerland)

Avec: Khanyisani Ziqubu , Christo J F Muller , Phiwayinkosi V Dludla , Sinenhlanhla X H Mthembu , Nnini Obonye , Johan Louw , Abidemi P Kappo , Sonia Silvestri , Patrick Orlando , Luca Tiano , Sithandiwe E Mazibuko-Mbeje

Experimental models of lipid overload and their relevance in understanding skeletal muscle insulin resistance and pathological changes in mitochondrial oxidative capacity.

Biochimie

Avec: Sinenhlanhla X H Mthembu , Phiwayinkosi V Dludla , Tawanda M Nyambuya , Abidemi P Kappo , Evelyn Madoroba , Khanyisani Ziqubu , Thembeka A Nyawo , Bongani B Nkambule , Sonia Silvestri , Christo J F Muller , Sithandiwe E Mazibuko-Mbeje

Vitamin K: A vital micronutrient with the cardioprotective potential against diabetes-associated complications.

Life sciences

Avec: Kabelo Mokgalaboni , Bongani B Nkambule , Yonela Ntamo , Khanyisani Ziqubu , Tawanda M Nyambuya , Sithandiwe E Mazibuko-Mbeje , Kwazikwakhe B Gabuza , Nireshni Chellan , Ilenia Cirilli , Luca Tiano , Phiwayinkosi V Dludla

Activated monocytes as a therapeutic target to attenuate vascular inflammation and lower cardiovascular disease-risk in patients with type 2 diabetes: A systematic review of preclinical and clinical studies.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Avec: Siphamandla R Ngcobo , Bongani B Nkambule , Tawanda M Nyambuya , Kabelo Mokgalaboni , Aviwe Ntsethe , Vuyolwethu Mxinwa , Khanyisani Ziqubu , Yonela Ntamo , Thembeka A Nyawo , Phiwayinkosi V Dludla

Anti-Obesity Effects of Metformin: A Scoping Review Evaluating the Feasibility of Brown Adipose Tissue as a Therapeutic Target.

International journal of molecular sciences

Avec: Khanyisani Ziqubu , Sithandiwe E Mazibuko-Mbeje , Sinenhlanhla X H Mthembu , Sihle E Mabhida , Babalwa U Jack , Tawanda M Nyambuya , Bongani B Nkambule , Albertus K Basson , Luca Tiano , Phiwayinkosi V Dludla

Disease progression promotes changes in adipose tissue signatures in type 2 diabetic (db/db) mice: The potential pathophysiological role of batokines.

Life sciences

Avec: Khanyisani Ziqubu , Phiwayinkosi V Dludla , Marakiya T Moetlediwa , Thembeka A Nyawo , Carmen Pheiffer , Babalwa U Jack , Bongani Nkambule , Sithandiwe E Mazibuko-Mbeje

Dietary Supplements Potentially Target Plasma Glutathione Levels to Improve Cardiometabolic Health in Patients with Diabetes Mellitus: A Systematic Review of Randomized Clinical Trials.

Nutrients

Avec: Phiwayinkosi V Dludla , Khanyisani Ziqubu , Sihle E Mabhida , Sithandiwe E Mazibuko-Mbeje , Sidney Hanser , Bongani B Nkambule , Albertus K Basson , Carmen Pheiffer , Luca Tiano , André P Kengne

Vitamin C intake potentially lowers total cholesterol to improve endothelial function in diabetic patients at increased risk of cardiovascular disease: A systematic review of randomized controlled trials.

Frontiers in nutrition

Avec: Phiwayinkosi V Dludla , Bongani B Nkambule , Tawanda M Nyambuya , Khanyisani Ziqubu , Sihle E Mabhida , Vuyolwethu Mxinwa , Kabelo Mokgalaboni , Fransina Ndevahoma , Sidney Hanser , Sithandiwe E Mazibuko-Mbeje , Albertus K Basson , Jacopo Sabbatinelli , Luca Tiano

Aspalathin, a natural product with the potential to reverse hepatic insulin resistance by improving energy metabolism and mitochondrial respiration.

PloS one

Avec: Sithandiwe E Mazibuko-Mbeje , Phiwayinkosi V Dludla , Rabia Johnson , Elizabeth Joubert , Johan Louw , Khanyisani Ziqubu , Luca Tiano , Sonia Silvestri , Patrick Orlando , Andy R Opoku , Christo J F Muller

Isoorientin: A dietary flavone with the potential to ameliorate diverse metabolic complications.

Pharmacological research

Avec: Khanyisani Ziqubu , Phiwayinkosi V Dludla , Elizabeth Joubert , Christo J F Muller , Johan Louw , Luca Tiano , Bongani B Nkambule , Abidemi P Kappo , Sithandiwe E Mazibuko-Mbeje

N-Acetyl Cysteine Targets Hepatic Lipid Accumulation to Curb Oxidative Stress and Inflammation in NAFLD: A Comprehensive Analysis of the Literature.

Antioxidants (Basel, Switzerland)

Avec: Phiwayinkosi V Dludla , Bongani B Nkambule , Sithandiwe E Mazibuko-Mbeje , Tawanda M Nyambuya , Fabio Marcheggiani , Ilenia Cirilli , Khanyisani Ziqubu , Samukelisiwe C Shabalala , Rabia Johnson , Johan Louw , Elisabetta Damiani , Luca Tiano

Tea consumption and its effects on primary and secondary prevention of coronary artery disease: Qualitative synthesis of evidence from randomized controlled trials.

Clinical nutrition ESPEN

Avec: Phiwayinkosi V Dludla , Bongani B Nkambule , Sithandiwe E Mazibuko-Mbeje , Tawanda M Nyambuya , Patrick Orlando , Sonia Silvestri , Fabio Marcheggiani , Ilenia Cirilli , Khanyisani Ziqubu , Fransina Ndevahoma , Vuyolwethu Mxinwa , Kabelo Mokgalaboni , Jacopo Sabbatinelli , Johan Louw , Luca Tiano

Rutin ameliorates inflammation and improves metabolic function: A comprehensive analysis of scientific literature.

Pharmacological research

Avec: Ndivhuwo Muvhulawa , Phiwayinkosi V Dludla , Khanyisani Ziqubu , Sinenhlanhla X H Mthembu , Fikile Mthiyane , Bongani B Nkambule , Sithandiwe E Mazibuko-Mbeje

Epigallocatechin gallate as a nutraceutical to potentially target the metabolic syndrome: novel insights into therapeutic effects beyond its antioxidant and anti-inflammatory properties.

Critical reviews in food science and nutrition

Avec: Yonela Ntamo , Babalwa Jack , Khanyisani Ziqubu , Sithandiwe E Mazibuko-Mbeje , Bongani B Nkambule , Tawanda M Nyambuya , Sihle E Mabhida , Sidney Hanser , Patrick Orlando , Luca Tiano , Phiwayinkosi V Dludla

Aspalathin alleviates skeletal muscle insulin resistance and mitochondrial dysfunction.

Physiological research

Avec: S E Mazibuko-Mbeje , S Xh Mthembu , C Jf Muller , N Muvhulawa , R V Modibedi , L Tiano , P V Dludla

Pancreatic β-cell dysfunction in type 2 diabetes: Implications of inflammation and oxidative stress.

World journal of diabetes

Avec: Phiwayinkosi V Dludla , Sihle E Mabhida , Khanyisani Ziqubu , Bongani B Nkambule , Sithandiwe E Mazibuko-Mbeje , Sidney Hanser , Albert Kotze Basson , Carmen Pheiffer , Andre Pascal Kengne

Potential regulatory role of PGC-1α within the skeletal muscle during metabolic adaptations in response to high-fat diet feeding in animal models.

Pflugers Archiv : European journal of physiology

Avec: Sinenhlanhla X H Mthembu , Sithandiwe E Mazibuko-Mbeje , Khanyisani Ziqubu , Ndivhuwo Muvhulawa , Fabio Marcheggiani , Ilenia Cirilli , Bongani B Nkambule , Christo J F Muller , Albertus K Basson , Luca Tiano , Phiwayinkosi V Dludla

Low circulating levels of neuregulin 4 as a potential biomarker associated with the severity and prognosis of obesity-related metabolic diseases: a systematic review.

Adipocyte

Avec: Khanyisani Ziqubu , Phiwayinkosi V Dludla , Sinenhlanhla X H Mthembu , Bongani Nkambule , Sithandiwe E Mazibuko-Mbeje

Réseau de co-auteurs

Khanyisani Ziqubu 34 collaborations

Phiwayinkosi V Dludla 33 collaborations

Sithandiwe E Mazibuko-Mbeje 31 collaborations

Bongani B Nkambule 25 collaborations

Luca Tiano 20 collaborations

Tawanda M Nyambuya 17 collaborations

Sinenhlanhla X H Mthembu 14 collaborations

Sihle E Mabhida 12 collaborations

Christo J F Muller 10 collaborations

Sonia Silvestri 9 collaborations

Patrick Orlando 7 collaborations

Johan Louw 7 collaborations

Albertus K Basson 7 collaborations

Yonela Ntamo 7 collaborations

Ilenia Cirilli 7 collaborations

Sidney Hanser 7 collaborations

Kabelo Mokgalaboni 7 collaborations

Thembeka A Nyawo 6 collaborations

Fabio Marcheggiani 6 collaborations

Abidemi P Kappo 5 collaborations

Ndivhuwo Muvhulawa 5 collaborations

Rabia Johnson 4 collaborations

Babalwa U Jack 4 collaborations

Nireshni Chellan 4 collaborations

Kwazikwakhe B Gabuza 4 collaborations

Vuyolwethu Mxinwa 4 collaborations

Carmen Pheiffer 3 collaborations

Evelyn Madoroba 2 collaborations

Nnini Obonye 2 collaborations

Charity Masilela 2 collaborations

Marakiya T Moetlediwa 2 collaborations

Babalwa Jack 2 collaborations

Samukelisiwe C Shabalala 2 collaborations

Nokulunga Hlengwa 2 collaborations

Fikile T Mthiyane 2 collaborations

André P Kengne 2 collaborations

Bongani Nkambule 2 collaborations

Fransina Ndevahoma 2 collaborations

Jacopo Sabbatinelli 2 collaborations

Elizabeth Joubert 2 collaborations

Babu Muhamed 1 collaboration

Jyoti R Sharma 1 collaboration

Teke Apalata 1 collaboration

Sibusiso Nomatshila 1 collaboration

Lawrence Mabasa 1 collaboration

Mongi Benjeddou 1 collaboration

Samukelisiwe Shabalala 1 collaboration

Susanne Keipert 1 collaboration

Martin Jastroch 1 collaboration

Duduzile Ndwandwe 1 collaboration

Jeanine L Marnewick 1 collaboration

Francois H Van der Westhuizen 1 collaboration

Andani Tshiitamune 1 collaboration

Zandile J Mchiza 1 collaboration

Joel Choshi 1 collaboration

Haskly Mokoena 1 collaboration

Duduzile E Ndwandwe 1 collaboration

Siphamandla R Ngcobo 1 collaboration

Aviwe Ntsethe 1 collaboration

Andy R Opoku 1 collaboration

Elisabetta Damiani 1 collaboration

Fikile Mthiyane 1 collaboration

S E Mazibuko-Mbeje 1 collaboration

S Xh Mthembu 1 collaboration

C Jf Muller 1 collaboration

N Muvhulawa 1 collaboration

R V Modibedi 1 collaboration

L Tiano 1 collaboration

P V Dludla 1 collaboration

Albert Kotze Basson 1 collaboration

Andre Pascal Kengne 1 collaboration