Accueil
Jennifer E Klomp
Jennifer E Klomp
Affiliations
Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
ORCID: 0000-0003-1781-648X
Publications (13)
Defining the KRAS- and ERK-dependent transcriptome in KRAS-mutant cancers.
Science (New York, N.Y.)
Avec:
Jeffrey A Klomp
,
Clint A Stalnecker
,
Kirsten L Bryant
,
A Cole Edwards
,
Kristina Drizyte-Miller
,
Priya S Hibshman
,
J Nathaniel Diehl
,
Ye S Lee
,
Alexis J Morales
,
Khalilah E Taylor
,
Sen Peng
,
Nhan L Tran
,
Laura E Herring
,
Alex W Prevatte
,
Natalie K Barker
,
Laura D Hover
,
Jill Hallin
,
Saikat Chowdhury
,
Oluwadara Coker
,
Hey Min Lee
,
Craig M Goodwin
,
Prson Gautam
,
Peter Olson
,
James G Christensen
,
John P Shen
,
Scott Kopetz
,
Lee M Graves
,
Kian-Huat Lim
,
Andrea Wang-Gillam
,
Krister Wennerberg
,
Adrienne D Cox
,
Channing J Der
Time-Variant SRC Kinase Activation Determines Endothelial Permeability Response.
Cell chemical biology
Avec:
Mark Shaaya
,
Jacob Matsche
,
Rima Rebiai
,
Jesse S Aaron
,
Kerrie B Collins
,
Vincent Huyot
,
Annette M Gonzalez
,
William A Muller
,
Teng-Leong Chew
,
Asrar B Malik
,
Andrei V Karginov
Atypical KRAS
Cancer discovery
Avec:
G Aaron Hobbs
,
Nicole M Baker
,
Anne M Miermont
,
Ryan D Thurman
,
Mariaelena Pierobon
,
Timothy H Tran
,
Andrew O Anderson
,
Andrew M Waters
,
J Nathaniel Diehl
,
Bjoern Papke
,
Richard G Hodge
,
Craig M Goodwin
,
Jonathan M DeLiberty
,
Junning Wang
,
Raymond W S Ng
,
Prson Gautam
,
Kirsten L Bryant
,
Dominic Esposito
,
Sharon L Campbell
,
Emanuel F Petricoin
,
Dhirendra K Simanshu
,
Andrew J Aguirre
,
Brian M Wolpin
,
Krister Wennerberg
,
Udo Rudloff
,
Adrienne D Cox
,
Channing J Der
Author Correction: Combination of ERK and autophagy inhibition as a treatment approach for pancreatic cancer.
Nature medicine
Avec:
Kirsten L Bryant
,
Clint A Stalnecker
,
Daniel Zeitouni
,
Sen Peng
,
Andrey P Tikunov
,
Venugopal Gunda
,
Mariaelena Pierobon
,
Andrew M Waters
,
Samuel D George
,
Garima Tomar
,
Björn Papke
,
G Aaron Hobbs
,
Liang Yan
,
Tikvah K Hayes
,
J Nathaniel Diehl
,
Gennifer D Goode
,
Nina V Chaika
,
Yingxue Wang
,
Guo-Fang Zhang
,
Agnieszka K Witkiewicz
,
Erik S Knudsen
,
Emanuel F Petricoin
,
Pankaj K Singh
,
Jeffrey M Macdonald
,
Nhan L Tran
,
Costas A Lyssiotis
,
Haoqiang Ying
,
Alec C Kimmelman
,
Adrienne D Cox
,
Channing J Der
Concurrent inhibition of oncogenic and wild-type RAS-GTP for cancer therapy.
Nature
Avec:
Matthew Holderfield
,
Bianca J Lee
,
Jingjing Jiang
,
Aidan Tomlinson
,
Kyle J Seamon
,
Alessia Mira
,
Enrico Patrucco
,
Grace Goodhart
,
Julien Dilly
,
Yevgeniy Gindin
,
Nuntana Dinglasan
,
Yingyun Wang
,
Lick Pui Lai
,
Shurui Cai
,
Lingyan Jiang
,
Nicole Nasholm
,
Nataliya Shifrin
,
Cristina Blaj
,
Harshit Shah
,
James W Evans
,
Nilufar Montazer
,
Oliver Lai
,
Jade Shi
,
Ethan Ahler
,
Elsa Quintana
,
Stephanie Chang
,
Anthony Salvador
,
Abby Marquez
,
Jim Cregg
,
Yang Liu
,
Anthony Milin
,
Anqi Chen
,
Tamar Bar Ziv
,
Dylan Parsons
,
John E Knox
,
Jennifer Roth
,
Matthew Rees
,
Melissa Ronan
,
Antonio Cuevas-Navarro
,
Feng Hu
,
Piro Lito
,
David Santamaria
,
Andrew J Aguirre
,
Andrew M Waters
,
Channing J Der
,
Chiara Ambrogio
,
Zhengping Wang
,
Adrian L Gill
,
Elena S Koltun
,
Jacqueline A M Smith
,
David Wildes
,
Mallika Singh
The KRAS-regulated kinome identifies WEE1 and ERK coinhibition as a potential therapeutic strategy in KRAS-mutant pancreatic cancer.
The Journal of biological chemistry
Avec:
J Nathaniel Diehl
,
Kayla R Snare
,
Priya S Hibshman
,
Devon R Blake
,
Zane D Kaiser
,
Thomas S K Gilbert
,
Elisa Baldelli
,
Mariaelena Pierobon
,
Björn Papke
,
Runying Yang
,
Richard G Hodge
,
Naim U Rashid
,
Emanuel F Petricoin
,
Laura E Herring
,
Lee M Graves
,
Adrienne D Cox
,
Channing J Der
Combination Therapies with CDK4/6 Inhibitors to Treat KRAS-Mutant Pancreatic Cancer.
Cancer research
Avec:
Craig M Goodwin
,
Andrew M Waters
,
Sehrish Javaid
,
Kirsten L Bryant
,
Clint A Stalnecker
,
Kristina Drizyte-Miller
,
Bjoern Papke
,
Runying Yang
,
Amber M Amparo
,
Irem Ozkan-Dagliyan
,
Elisa Baldelli
,
Valerie Calvert
,
Mariaelena Pierobon
,
Jessica A Sorrentino
,
Andrew P Beelen
,
Natalie Bublitz
,
Mareen Lüthen
,
Kris C Wood
,
Emanuel F Petricoin
,
Christine Sers
,
Autumn J McRee
,
Adrienne D Cox
,
Channing J Der
VCP/p97, a pleiotropic protein regulator of the DNA damage response and proteostasis, is a potential therapeutic target in
Genes & cancer
Avec:
Ye S Lee
,
Clint A Stalnecker
,
Craig M Goodwin
,
Yanzhe Gao
,
Gaith N Droby
,
Cyrus Vaziri
,
Kirsten L Bryant
,
Channing J Der
,
Adrienne D Cox
Determining the ERK-regulated phosphoproteome driving KRAS-mutant cancer.
Science (New York, N.Y.)
Avec:
J Nathaniel Diehl
,
Jeffrey A Klomp
,
A Cole Edwards
,
Runying Yang
,
Alexis J Morales
,
Khalilah E Taylor
,
Kristina Drizyte-Miller
,
Kirsten L Bryant
,
Antje Schaefer
,
Jared L Johnson
,
Emily M Huntsman
,
Tomer M Yaron
,
Mariaelena Pierobon
,
Elisa Baldelli
,
Alex W Prevatte
,
Natalie K Barker
,
Laura E Herring
,
Emanuel F Petricoin
,
Lee M Graves
,
Lewis C Cantley
,
Adrienne D Cox
,
Channing J Der
,
Clint A Stalnecker
Comprehensive transcriptomic profiling reveals SOX7 as an early regulator of angiogenesis in hypoxic human endothelial cells.
The Journal of biological chemistry
Avec:
Jeff Klomp
,
James Hyun
,
Kostandin Pajcini
,
Jalees Rehman
,
Asrar B Malik
CHK1 protects oncogenic KRAS-expressing cells from DNA damage and is a target for pancreatic cancer treatment.
Cell reports
Avec:
Ye S Lee
,
Craig M Goodwin
,
Björn Papke
,
Jeff A Klomp
,
Andrew M Waters
,
Clint A Stalnecker
,
Jonathan M DeLiberty
,
Kristina Drizyte-Miller
,
Runying Yang
,
J Nathaniel Diehl
,
Hongwei H Yin
,
Mariaelena Pierobon
,
Elisa Baldelli
,
Meagan B Ryan
,
Siqi Li
,
Jackson Peterson
,
Amber R Smith
,
James T Neal
,
Aaron K McCormick
,
Calvin J Kuo
,
Christopher M Counter
,
Emanuel F Petricoin
,
Adrienne D Cox
,
Kirsten L Bryant
,
Channing J Der
Targeting p130Cas- and microtubule-dependent MYC regulation sensitizes pancreatic cancer to ERK MAPK inhibition.
Cell reports
Avec:
Andrew M Waters
,
Tala O Khatib
,
Bjoern Papke
,
Craig M Goodwin
,
G Aaron Hobbs
,
J Nathaniel Diehl
,
Runying Yang
,
A Cole Edwards
,
Katherine H Walsh
,
Rita Sulahian
,
James M McFarland
,
Kevin S Kapner
,
Thomas S K Gilbert
,
Clint A Stalnecker
,
Sehrish Javaid
,
Anna Barkovskaya
,
Kajal R Grover
,
Priya S Hibshman
,
Devon R Blake
,
Antje Schaefer
,
Katherine M Nowak
,
Tikvah K Hayes
,
Michelle Kassner
,
Nanyun Tang
,
Olga Tanaseichuk
,
Kaisheng Chen
,
Yingyao Zhou
,
Manpreet Kalkat
,
Laura E Herring
,
Lee M Graves
,
Linda Z Penn
,
Hongwei H Yin
,
Andrew J Aguirre
,
William C Hahn
,
Adrienne D Cox
,
Channing J Der
TEAD Inhibition Overcomes YAP1/TAZ-driven Primary and Acquired Resistance to KRASG12C Inhibitors.
Cancer research
Avec:
A Cole Edwards
,
Clint A Stalnecker
,
Alexis Jean Morales
,
Khalilah E Taylor
,
Jeffrey A Klomp
,
Andrew M Waters
,
Niranjan Sudhakar
,
Jill Hallin
,
Tracy T Tang
,
Peter Olson
,
Leonard Post
,
James G Christensen
,
Adrienne D Cox
,
Channing J Der
Réseau de co-auteurs
Channing J Der
11 collaborations
Adrienne D Cox
10 collaborations
Clint A Stalnecker
8 collaborations
Kirsten L Bryant
7 collaborations
J Nathaniel Diehl
7 collaborations
Andrew M Waters
7 collaborations
Craig M Goodwin
6 collaborations
Mariaelena Pierobon
6 collaborations
Emanuel F Petricoin
6 collaborations
Runying Yang
5 collaborations
A Cole Edwards
4 collaborations
Kristina Drizyte-Miller
4 collaborations
Laura E Herring
4 collaborations
Lee M Graves
4 collaborations
Elisa Baldelli
4 collaborations
Jeffrey A Klomp
3 collaborations
Priya S Hibshman
3 collaborations
Ye S Lee
3 collaborations
Khalilah E Taylor
3 collaborations
G Aaron Hobbs
3 collaborations
Bjoern Papke
3 collaborations
Andrew J Aguirre
3 collaborations
Björn Papke
3 collaborations
Alexis J Morales
2 collaborations
Sen Peng
2 collaborations
Nhan L Tran
2 collaborations
Alex W Prevatte
2 collaborations
Natalie K Barker
2 collaborations
Jill Hallin
2 collaborations
Prson Gautam
2 collaborations
Peter Olson
2 collaborations
James G Christensen
2 collaborations
Krister Wennerberg
2 collaborations
Asrar B Malik
2 collaborations
Richard G Hodge
2 collaborations
Jonathan M DeLiberty
2 collaborations
Tikvah K Hayes
2 collaborations
Devon R Blake
2 collaborations
Thomas S K Gilbert
2 collaborations
Sehrish Javaid
2 collaborations
Antje Schaefer
2 collaborations
Hongwei H Yin
2 collaborations
Laura D Hover
1 collaboration
Saikat Chowdhury
1 collaboration
Oluwadara Coker
1 collaboration
Hey Min Lee
1 collaboration
John P Shen
1 collaboration
Scott Kopetz
1 collaboration
Kian-Huat Lim
1 collaboration
Andrea Wang-Gillam
1 collaboration
Mark Shaaya
1 collaboration
Jacob Matsche
1 collaboration
Rima Rebiai
1 collaboration
Jesse S Aaron
1 collaboration
Kerrie B Collins
1 collaboration
Vincent Huyot
1 collaboration
Annette M Gonzalez
1 collaboration
William A Muller
1 collaboration
Teng-Leong Chew
1 collaboration
Andrei V Karginov
1 collaboration
Nicole M Baker
1 collaboration
Anne M Miermont
1 collaboration
Ryan D Thurman
1 collaboration
Timothy H Tran
1 collaboration
Andrew O Anderson
1 collaboration
Junning Wang
1 collaboration
Raymond W S Ng
1 collaboration
Dominic Esposito
1 collaboration
Sharon L Campbell
1 collaboration
Dhirendra K Simanshu
1 collaboration
Brian M Wolpin
1 collaboration
Udo Rudloff
1 collaboration
Daniel Zeitouni
1 collaboration
Andrey P Tikunov
1 collaboration
Venugopal Gunda
1 collaboration
Samuel D George
1 collaboration
Garima Tomar
1 collaboration
Liang Yan
1 collaboration
Gennifer D Goode
1 collaboration
Nina V Chaika
1 collaboration
Yingxue Wang
1 collaboration
Guo-Fang Zhang
1 collaboration
Agnieszka K Witkiewicz
1 collaboration
Erik S Knudsen
1 collaboration
Pankaj K Singh
1 collaboration
Jeffrey M Macdonald
1 collaboration
Costas A Lyssiotis
1 collaboration
Haoqiang Ying
1 collaboration
Alec C Kimmelman
1 collaboration
Matthew Holderfield
1 collaboration
Bianca J Lee
1 collaboration
Jingjing Jiang
1 collaboration
Aidan Tomlinson
1 collaboration
Kyle J Seamon
1 collaboration
Alessia Mira
1 collaboration
Enrico Patrucco
1 collaboration
Grace Goodhart
1 collaboration
Julien Dilly
1 collaboration
Yevgeniy Gindin
1 collaboration
Nuntana Dinglasan
1 collaboration
Yingyun Wang
1 collaboration
Lick Pui Lai
1 collaboration
Shurui Cai
1 collaboration
Lingyan Jiang
1 collaboration
Nicole Nasholm
1 collaboration
Nataliya Shifrin
1 collaboration
Cristina Blaj
1 collaboration
Harshit Shah
1 collaboration
James W Evans
1 collaboration
Nilufar Montazer
1 collaboration
Oliver Lai
1 collaboration
Jade Shi
1 collaboration
Ethan Ahler
1 collaboration
Elsa Quintana
1 collaboration
Stephanie Chang
1 collaboration
Anthony Salvador
1 collaboration
Abby Marquez
1 collaboration
Jim Cregg
1 collaboration
Yang Liu
1 collaboration
Anthony Milin
1 collaboration
Anqi Chen
1 collaboration
Tamar Bar Ziv
1 collaboration
Dylan Parsons
1 collaboration
John E Knox
1 collaboration
Jennifer Roth
1 collaboration
Matthew Rees
1 collaboration
Melissa Ronan
1 collaboration
Antonio Cuevas-Navarro
1 collaboration
Feng Hu
1 collaboration
Piro Lito
1 collaboration
David Santamaria
1 collaboration
Chiara Ambrogio
1 collaboration
Zhengping Wang
1 collaboration
Adrian L Gill
1 collaboration
Elena S Koltun
1 collaboration
Jacqueline A M Smith
1 collaboration
David Wildes
1 collaboration
Mallika Singh
1 collaboration
Kayla R Snare
1 collaboration
Zane D Kaiser
1 collaboration
Naim U Rashid
1 collaboration
Amber M Amparo
1 collaboration
Irem Ozkan-Dagliyan
1 collaboration
Valerie Calvert
1 collaboration
Jessica A Sorrentino
1 collaboration
Andrew P Beelen
1 collaboration
Natalie Bublitz
1 collaboration
Mareen Lüthen
1 collaboration
Kris C Wood
1 collaboration
Christine Sers
1 collaboration
Autumn J McRee
1 collaboration
Yanzhe Gao
1 collaboration
Gaith N Droby
1 collaboration
Cyrus Vaziri
1 collaboration
Jared L Johnson
1 collaboration
Emily M Huntsman
1 collaboration
Tomer M Yaron
1 collaboration
Lewis C Cantley
1 collaboration
Jeff Klomp
1 collaboration
James Hyun
1 collaboration
Kostandin Pajcini
1 collaboration
Jalees Rehman
1 collaboration
Jeff A Klomp
1 collaboration
Meagan B Ryan
1 collaboration
Siqi Li
1 collaboration
Jackson Peterson
1 collaboration
Amber R Smith
1 collaboration
James T Neal
1 collaboration
Aaron K McCormick
1 collaboration
Calvin J Kuo
1 collaboration
Christopher M Counter
1 collaboration
Tala O Khatib
1 collaboration
Katherine H Walsh
1 collaboration
Rita Sulahian
1 collaboration
James M McFarland
1 collaboration
Kevin S Kapner
1 collaboration
Anna Barkovskaya
1 collaboration
Kajal R Grover
1 collaboration
Katherine M Nowak
1 collaboration
Michelle Kassner
1 collaboration
Nanyun Tang
1 collaboration
Olga Tanaseichuk
1 collaboration
Kaisheng Chen
1 collaboration
Yingyao Zhou
1 collaboration
Manpreet Kalkat
1 collaboration
Linda Z Penn
1 collaboration
William C Hahn
1 collaboration
Alexis Jean Morales
1 collaboration
Niranjan Sudhakar
1 collaboration
Tracy T Tang
1 collaboration
Leonard Post
1 collaboration